Probióticos para la prevención de la infección urinaria en pacientes con vejiga neuropática
Información
- DOI:
- https://doi.org/10.1002/14651858.CD010723.pub2Copiar DOI
- Base de datos:
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- Cochrane Database of Systematic Reviews
- Versión publicada:
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- 08 septiembre 2017see what's new
- Tipo:
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- Intervention
- Etapa:
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- Review
- Grupo Editorial Cochrane:
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Grupo Cochrane de Riñón y trasplante
- Copyright:
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- Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Cifras del artículo
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Autores
Contributions of authors
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Draft the protocol: CBR, ST
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Study selection: CBR, ST
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Extract data from studies: CBR, ST
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Enter data into RevMan: CBR, ST
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Carry out the analysis: CBR, ST
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Interpret the analysis: CBR, ST, JMS, KC
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Draft the final review: CBR, ST, KC
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Disagreement resolution: BL
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Update the review: CBR, ST
Sources of support
Internal sources
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No sources of support supplied
External sources
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NHMRC, Australia.
Project Grant Application: 630448
Declarations of interest
Dr Lee is the lead investigator of NHMRC Project Grant Application: 630448 Probiotic Prophylaxis of Spinal Cord Injury Urinary Tract‐Infection TherapeUtic‐Trial (ProSCIUTTU), which is an Australian government‐sponsored study looking at the effectiveness of Probiotic therapy in preventing urinary tract infection and multidrug resistance. Dr Toh is completing a PhD looking at whether probiotics can prevent UTI in patients with spinal cord injury and neurogenic bladders. Dr Toh and Dr Boswell‐Ruys are also assisting in the ProSCIUTTU trial. No other authors had any declarations of interest.
Acknowledgements
We would like to acknowledge Cochrane Kidney and Transplant for their assistance with this review. We are also grateful for comments and feedback from the peer referees during preparation of the review. Also Professor Wullt for providing further data and clarification.
Version history
| Published | Title | Stage | Authors | Version |
| 2017 Sep 08 | Probiotics for preventing urinary tract infection in people with neuropathic bladder | Review | Swee‐Ling Toh, Claire L Boswell‐Ruys, Bon San B Lee, Judy M Simpson, Kate R Clezy | |
| 2013 Sep 03 | Probiotics for preventing urinary tract infection in people with neuropathic bladder | Protocol | Claire L Boswell‐Ruys, Swee‐Ling Toh, Bon San B Lee, Judy M Simpson, Kate R Clezy | |
Differences between protocol and review
Summary of findings table has been incorporated.
Keywords
MeSH
Medical Subject Headings (MeSH) Keywords
Medical Subject Headings Check Words
Adult; Child; Female; Humans; Male;
PICO
Study flow diagram.
Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
Comparison 1 Intravesical bacterial interference, Outcome 1 Symptomatic UTI.
| Intravesical bacterial interference versus placebo for preventing urinary tract infection in people with neuropathic bladder | |||||
| Patient or population: people with neuropathic bladder | |||||
| Outcomes | Anticipated absolute effects* (95% CI) | Relative effect | No. of participants (studies) | Quality of the evidence | |
| Risk with placebo | Risk with intravesical bacterial interference | ||||
| Symptomatic UTI | 613 per 1,000 | 196 per 1,000 | RR 0.32 | 110 (3) | ⊕⊝⊝⊝1 |
| GRADE Working Group grades of evidence | |||||
| 1Risk of bias was assessed at high in most domains, with heterogeneity and small studies, suggesting that results overestimate intravesical bacterial interference versus placebo | |||||
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 Symptomatic UTI Show forest plot | 3 | 110 | Risk Ratio (M‐H, Random, 95% CI) | 0.32 [0.08, 1.19] |
