Profilaxis antimicrobiana sistémica para la gastrostomía endoscópica percutánea
Información
- DOI:
- https://doi.org/10.1002/14651858.CD005571.pub3Copiar DOI
- Base de datos:
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- Cochrane Database of Systematic Reviews
- Versión publicada:
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- 14 noviembre 2013see what's new
- Tipo:
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- Intervention
- Etapa:
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- Review
- Grupo Editorial Cochrane:
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Grupo Cochrane de Heridas
- Copyright:
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- Copyright © 2013 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Cifras del artículo
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Autores
Contributions of authors
AL took the lead in writing the protocol and the review, provided overall methodological expertise, entered data into RevMan, contacted authors, was involved in selecting trials for the review, performed independent data extraction and quality assessment of included studies.
GL assisted in writing the protocol and the review, provided clinical expertise, contacted specialist organisations, was involved in selecting trials for the review, performed independent data extraction and quality assessment of included trials.
Both authors revised the manuscript after peer review and read and approved the final version. Both authors contributed equally to all updates.
Contributions of editorial base:
Nicky Cullum: edited the review, advised on methodology, interpretation and review content. Approved the final review and review update prior to submission.
Sally Bell‐Syer: coordinated the editorial process. Advised on methodology, interpretation and content. Edited the review and the updated review.
Ruth Foxlee: designed the search strategy, ran the searches and edited the search methods section for the update.
Sources of support
Internal sources
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Faculty of Health, Sport and Science, University of Glamorgan, UK.
External sources
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NIHR/Department of Health (England), (Cochrane Wounds Group), UK.
Declarations of interest
None known.
Acknowledgements
The authors would like to thank their employer, the University of Glamorgan, for allowing them the time and resources to undertake the review.
The authors would like to thank the following referees for their comments on the review: Cochrane Wounds Group Editors (Michelle Briggs, Nicky Cullum, Gill Cranny, David Margolis); Referees (Zoe Hodges, Ernst Kuipers, David Leaper, Caroline Main, Barbara Postle) and Copy Editor, Elizabeth Royle.
Version history
| Published | Title | Stage | Authors | Version |
| 2013 Nov 14 | Systemic antimicrobial prophylaxis for percutaneous endoscopic gastrostomy | Review | Allyson Lipp, Gail Lusardi | |
| 2006 Oct 18 | Systemic antimicrobial prophylaxis for percutaneous endoscopic gastrostomy | Review | Allyson Lipp, Gail Lusardi | |
| 2006 Jan 25 | Systemic antimicrobial prophylaxis for percutaneous endoscopic gastrostomy | Protocol | Allyson Lipp, Gail Lusardi | |
Keywords
MeSH
Medical Subject Headings (MeSH) Keywords
Medical Subject Headings Check Words
Humans;
PICO
Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
Methodological quality summary: review authors' judgements about each methodological quality item for each included study.
Comparison 1 Systemic antibiotic (IV) compared with placebo, Outcome 1 Peristomal infection.
Comparison 2 Systemic antibiotic (IV) compared with no intervention, Outcome 1 Peristomal infection.
Comparison 3 Systemic antibiotic (IV) compared with placebo/no intervention/skin antiseptic, Outcome 1 Peristomal infection.
Comparison 3 Systemic antibiotic (IV) compared with placebo/no intervention/skin antiseptic, Outcome 2 Allocation concealment.
Comparison 3 Systemic antibiotic (IV) compared with placebo/no intervention/skin antiseptic, Outcome 3 Sponsorship.
Comparison 4 Systemic antibiotic compared with systemic antibiotic, Outcome 1 Systemic antibiotic (IV) compared with systemic antibiotic (IV).
Comparison 4 Systemic antibiotic compared with systemic antibiotic, Outcome 2 Systemic antibiotic (PEG) compared with systemic antibiotic (IV).
Comparison 5 Systemic antibiotic (IV) compared with systemic antibiotic (IV) and skin antiseptic, Outcome 1 Peristomal infection.
Comparison 6 Skin antiseptic compared with systemic antibiotic (IV) and skin antiseptic, Outcome 1 Peristomal infection.
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 Peristomal infection Show forest plot | 8 | 586 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.34 [0.22, 0.53] |
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 Peristomal infection Show forest plot | 3 | 623 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.30 [0.17, 0.53] |
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 Peristomal infection Show forest plot | 12 | 1271 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.36 [0.26, 0.50] |
| 2 Allocation concealment Show forest plot | 12 | 1271 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.47 [0.34, 0.65] |
| 2.1 adequate allocation concealment | 8 | 554 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.58 [0.38, 0.88] |
| 2.2 unclear/inadequate concealment | 4 | 717 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.34 [0.21, 0.58] |
| 3 Sponsorship Show forest plot | 12 | 1271 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.36 [0.26, 0.50] |
| 3.1 Trials with no sponsorship | 10 | 962 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.38 [0.25, 0.56] |
| 3.2 Trials with sponsorship | 2 | 309 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.32 [0.18, 0.58] |
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 Systemic antibiotic (IV) compared with systemic antibiotic (IV) Show forest plot | 1 | Odds Ratio (M‐H, Fixed, 95% CI) | Totals not selected | |
| 1.1 Peristomal infection | 1 | Odds Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] | |
| 2 Systemic antibiotic (PEG) compared with systemic antibiotic (IV) Show forest plot | 1 | Odds Ratio (M‐H, Fixed, 95% CI) | Totals not selected | |
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 Peristomal infection Show forest plot | 1 | 68 | Odds Ratio (M‐H, Fixed, 95% CI) | 15.78 [1.90, 130.86] |
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 Peristomal infection Show forest plot | 1 | 62 | Odds Ratio (M‐H, Fixed, 95% CI) | 15.63 [1.84, 133.09] |
