Scolaris Content Display Scolaris Content Display

Comparison 1 Short‐term: nocturnal ventilation versus no ventilation, Outcome 1 No improvement of hypoventilation symptoms.
Figuras y tablas -
Analysis 1.1

Comparison 1 Short‐term: nocturnal ventilation versus no ventilation, Outcome 1 No improvement of hypoventilation symptoms.

Comparison 1 Short‐term: nocturnal ventilation versus no ventilation, Outcome 2 No improvement of daytime hypercapnia.
Figuras y tablas -
Analysis 1.2

Comparison 1 Short‐term: nocturnal ventilation versus no ventilation, Outcome 2 No improvement of daytime hypercapnia.

Comparison 1 Short‐term: nocturnal ventilation versus no ventilation, Outcome 3 Daytime PaCO2.
Figuras y tablas -
Analysis 1.3

Comparison 1 Short‐term: nocturnal ventilation versus no ventilation, Outcome 3 Daytime PaCO2.

Comparison 1 Short‐term: nocturnal ventilation versus no ventilation, Outcome 4 Mean nocturnal SaO2.
Figuras y tablas -
Analysis 1.4

Comparison 1 Short‐term: nocturnal ventilation versus no ventilation, Outcome 4 Mean nocturnal SaO2.

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 1 Unplanned admission to hospital.
Figuras y tablas -
Analysis 2.1

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 1 Unplanned admission to hospital.

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 2 Death.
Figuras y tablas -
Analysis 2.2

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 2 Death.

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 3 No improvement of hypoventilation symptoms.
Figuras y tablas -
Analysis 2.3

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 3 No improvement of hypoventilation symptoms.

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 4 No improvement of daytime hypercapnia.
Figuras y tablas -
Analysis 2.4

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 4 No improvement of daytime hypercapnia.

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 5 Daytime PaCO2.
Figuras y tablas -
Analysis 2.5

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 5 Daytime PaCO2.

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 6 Forced vital capacity.
Figuras y tablas -
Analysis 2.6

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 6 Forced vital capacity.

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 7 Respiratory muscle strength.
Figuras y tablas -
Analysis 2.7

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 7 Respiratory muscle strength.

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 8 Mean nocturnal SaO2.
Figuras y tablas -
Analysis 2.8

Comparison 2 Long‐term: nocturnal ventilation versus no ventilation, Outcome 8 Mean nocturnal SaO2.

Comparison 3 Short‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 1 No improvement of hypoventilation symptoms.
Figuras y tablas -
Analysis 3.1

Comparison 3 Short‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 1 No improvement of hypoventilation symptoms.

Comparison 3 Short‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 2 No improvement of daytime hypercapnia.
Figuras y tablas -
Analysis 3.2

Comparison 3 Short‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 2 No improvement of daytime hypercapnia.

Comparison 3 Short‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 3 Daytime PaCO2.
Figuras y tablas -
Analysis 3.3

Comparison 3 Short‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 3 Daytime PaCO2.

Comparison 3 Short‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 4 Mean nocturnal SaO2.
Figuras y tablas -
Analysis 3.4

Comparison 3 Short‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 4 Mean nocturnal SaO2.

Comparison 4 Long‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 1 No improvement of daytime hypercapnia.
Figuras y tablas -
Analysis 4.1

Comparison 4 Long‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 1 No improvement of daytime hypercapnia.

Comparison 4 Long‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 2 Daytime PaCO2.
Figuras y tablas -
Analysis 4.2

Comparison 4 Long‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 2 Daytime PaCO2.

Comparison 4 Long‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 3 Apnea‐hypopnea index.
Figuras y tablas -
Analysis 4.3

Comparison 4 Long‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 3 Apnea‐hypopnea index.

Comparison 4 Long‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 4 Mean nocturnal SaO2.
Figuras y tablas -
Analysis 4.4

Comparison 4 Long‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 4 Mean nocturnal SaO2.

Comparison 4 Long‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 5 Time spent with an SaO2 below 90%.
Figuras y tablas -
Analysis 4.5

Comparison 4 Long‐term: volume‐cycled ventilation versus pressure‐cycled ventilation, Outcome 5 Time spent with an SaO2 below 90%.

Table 1. Methodological quality of included studies

Study ID

Allocation
Concealment

Observer
blinding

Explicit
diagnostic
criteria

Explicit
outcome
criteria

Baseline
differences

Completeness
of follow‐up

Ellis 1987

C

C

B

A

B

A

Pinto 1995

C

C

A

A

A

A

Raphaël 1994

A

C

A

A

A

A

Restrick 1993

A

C

B

B

A

A

Laserna 2003

C

C

A

A

A

A

Wilson 2004

C

C

A

A

A

A

Ward 2005

C

C

A

A

A

B

Bourke 2006

A

C

A

A

A

A

Figuras y tablas -
Table 1. Methodological quality of included studies
Comparison 1. Short‐term: nocturnal ventilation versus no ventilation

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 No improvement of hypoventilation symptoms Show forest plot

1

10

Risk Ratio (M‐H, Fixed, 95% CI)

0.09 [0.01, 1.31]

2 No improvement of daytime hypercapnia Show forest plot

3

43

Risk Ratio (M‐H, Fixed, 95% CI)

0.37 [0.20, 0.65]

3 Daytime PaCO2 Show forest plot

2

24

Mean Difference (IV, Fixed, 95% CI)

‐0.32 [‐0.84, 0.20]

4 Mean nocturnal SaO2 Show forest plot

2

24

Mean Difference (IV, Fixed, 95% CI)

5.45 [1.47, 9.44]

Figuras y tablas -
Comparison 1. Short‐term: nocturnal ventilation versus no ventilation
Comparison 2. Long‐term: nocturnal ventilation versus no ventilation

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Unplanned admission to hospital Show forest plot

1

19

Risk Ratio (M‐H, Fixed, 95% CI)

0.13 [0.01, 2.22]

2 Death Show forest plot

3

80

Risk Ratio (M‐H, Fixed, 95% CI)

0.62 [0.42, 0.91]

3 No improvement of hypoventilation symptoms Show forest plot

1

19

Risk Ratio (M‐H, Fixed, 95% CI)

0.51 [0.22, 1.19]

4 No improvement of daytime hypercapnia Show forest plot

1

20

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

5 Daytime PaCO2 Show forest plot

3

60

Mean Difference (IV, Fixed, 95% CI)

‐0.26 [‐0.61, 0.09]

6 Forced vital capacity Show forest plot

2

28

Mean Difference (IV, Fixed, 95% CI)

158.50 [‐84.43, 401.43]

7 Respiratory muscle strength Show forest plot

1

28

Mean Difference (IV, Fixed, 95% CI)

‐5.72 [‐13.87, 2.43]

7.1 mean improvement in maximal inspiratory pressure

1

2

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

7.2 mean improvement in SNIP

1

26

Mean Difference (IV, Fixed, 95% CI)

‐5.72 [‐13.87, 2.43]

8 Mean nocturnal SaO2 Show forest plot

1

26

Mean Difference (IV, Fixed, 95% CI)

3.00 [1.85, 4.15]

Figuras y tablas -
Comparison 2. Long‐term: nocturnal ventilation versus no ventilation
Comparison 3. Short‐term: volume‐cycled ventilation versus pressure‐cycled ventilation

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 No improvement of hypoventilation symptoms Show forest plot

1

14

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

2 No improvement of daytime hypercapnia Show forest plot

1

14

Risk Ratio (M‐H, Fixed, 95% CI)

1.33 [0.46, 3.88]

3 Daytime PaCO2 Show forest plot

1

14

Mean Difference (IV, Fixed, 95% CI)

0.24 [‐0.38, 0.86]

4 Mean nocturnal SaO2 Show forest plot

1

14

Mean Difference (IV, Fixed, 95% CI)

‐0.49 [‐3.28, 2.30]

Figuras y tablas -
Comparison 3. Short‐term: volume‐cycled ventilation versus pressure‐cycled ventilation
Comparison 4. Long‐term: volume‐cycled ventilation versus pressure‐cycled ventilation

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 No improvement of daytime hypercapnia Show forest plot

1

20

Risk Ratio (M‐H, Fixed, 95% CI)

1.0 [0.49, 2.05]

2 Daytime PaCO2 Show forest plot

1

20

Mean Difference (IV, Fixed, 95% CI)

‐0.21 [‐0.69, 0.27]

3 Apnea‐hypopnea index Show forest plot

1

20

Mean Difference (IV, Fixed, 95% CI)

2.5 [‐0.60, 5.60]

4 Mean nocturnal SaO2 Show forest plot

1

2

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

5 Time spent with an SaO2 below 90% Show forest plot

1

20

Mean Difference (IV, Fixed, 95% CI)

2.0 [‐42.74, 46.74]

Figuras y tablas -
Comparison 4. Long‐term: volume‐cycled ventilation versus pressure‐cycled ventilation