Graduated compression stockings for prevention of deep vein thrombosis
Información
- DOI:
- https://doi.org/10.1002/14651858.CD001484.pub3Copiar DOI
- Base de datos:
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- Cochrane Database of Systematic Reviews
- Versión publicada:
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- 17 diciembre 2014see what's new
- Tipo:
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- Intervention
- Etapa:
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- Review
- Grupo Editorial Cochrane:
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Grupo Cochrane de Vascular
- Copyright:
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- Copyright © 2015 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Cifras del artículo
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Autores
Contributions of authors
2014 update
Ashwin Sachdeva (AS): selected trials for inclusion; assessed quality of trials; extracted data; updated review
Mark Dalton (MJD): selected trials for inclusion; cross‐checked and authenticated data extraction; assessed quality of trials; updated review
Sachi Amaragiri (SVA): rechecked and authenticated the selected trials for inclusion; checked the updated review
Timothy Lees (TAL): rechecked and authenticated the selected trials for inclusion; checked the updated review
Previous review updates
Ashwin Sachdeva (AS): selected trials for inclusion; assessed quality of trials; extracted data; updated review
Mark Dalton (MJD): selected trials for inclusion; assessed quality of trials; updated review
Sachi Amaragiri (SVA): selected trials for inclusion; assessed quality of trials; checked the updated review
Timothy Lees (TAL): rechecked and authenticated the selected trials for inclusion; assessed quality of trials; cross‐checked data; checked the updated review
Sources of support
Internal sources
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No sources of support supplied
External sources
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Chief Scientist Office, Scottish Government Health Directorates, The Scottish Government, UK.
The PVD Group editorial base is supported by the Chief Scientist Office
Declarations of interest
None known
Acknowledgements
The authors would like to thank Dr Karen Welch and Dr Cathryn Broderick for their support in updating this review.
Version history
| Published | Title | Stage | Authors | Version |
| 2018 Nov 03 | Graduated compression stockings for prevention of deep vein thrombosis | Review | Ashwin Sachdeva, Mark Dalton, Timothy Lees | |
| 2014 Dec 17 | Graduated compression stockings for prevention of deep vein thrombosis | Review | Ashwin Sachdeva, Mark Dalton, Sachiendra V Amaragiri, Timothy Lees | |
| 2010 Jul 07 | Elastic compression stockings for prevention of deep vein thrombosis | Review | Ashwin Sachdeva, Mark Dalton, Sachiendra V Amaragiri, Timothy Lees | |
| 2000 Jan 24 | Elastic compression stockings for prevention of deep vein thrombosis | Review | Sachiendra V Amaragiri, Timothy Lees | |
Differences between protocol and review
Two trials including stroke patients (CLOTS 2009; Muir 2000) were excluded from this review as they are the subject of another review undertaken by the Cochrane Stroke group (Naccarato 2010).
Previous versions of this review divided trials into two groups: GCS as sole method of thromboprophylaxis (that is those which compared GCS alone versus no thromboprophylaxis) and GCS as adjuvant method of thromboprophylaxis (that is those which compared GCS over a background of method of thromboprophylaxis versus background method of thromboprophylaxis alone). Since both these groups of trials test the same treatment effect (that is with stockings versus without stockings), all trials were merged in the 2014 update to increase the power of the review.
Keywords
MeSH
Medical Subject Headings (MeSH) Keywords
Medical Subject Headings Check Words
Humans;
PICO
Study flow diagram.
Methodological quality summary: review authors' judgements about each methodological quality item for each included study.
Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.
Funnel plot of comparison: Incidence of DVT with stockings and without stockings (all specialties).
Pie chart depicting the number of participants from each specialty included in the meta‐analysis.
Funnel plot of comparison: Incidence of proximal DVT with stockings and without stockings (all specialties).
Funnel plot of comparison: Incidence of PE with stockings and without stockings (all specialties).
Comparison 1 Incidence of DVT with stockings and without stockings, Outcome 1 All Specialties.
Comparison 2 Incidence of proximal DVT with stockings and without stockings, Outcome 1 All Specialties.
Comparison 3 Incidence of PE with stockings and without stockings, Outcome 1 All Specialties.
Comparison 4 Sensitivity analysis, Outcome 1 Method of randomisation.
Comparison 4 Sensitivity analysis, Outcome 2 Unit of Analysis for randomisation.
Comparison 4 Sensitivity analysis, Outcome 3 Use of background method of thromboprophylaxis.
Comparison 4 Sensitivity analysis, Outcome 4 Method of diagnosis.
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 All Specialties Show forest plot | 19 | 2745 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.33 [0.26, 0.41] |
| 1.1 General Surgery | 9 | 1378 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.27 [0.20, 0.38] |
| 1.2 Orthopaedic Surgery | 6 | 598 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.47 [0.32, 0.68] |
| 1.3 Other Specialties | 4 | 769 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.28 [0.16, 0.48] |
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 All Specialties Show forest plot | 8 | 1035 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.26 [0.13, 0.53] |
| 1.1 General Surgery | 2 | 316 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.14 [0.00, 6.82] |
| 1.2 Orthopaedic Surgery | 4 | 398 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.25 [0.12, 0.53] |
| 1.3 Other Specialties | 2 | 321 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.52 [0.05, 5.03] |
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 All Specialties Show forest plot | 5 | 569 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.38 [0.15, 0.96] |
| 1.1 General Surgery | 2 | 271 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.33 [0.09, 1.24] |
| 1.2 Orthopaedic Surgery | 3 | 298 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.44 [0.12, 1.58] |
| 1.3 Other Specialties | 0 | 0 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 Method of randomisation Show forest plot | 19 | 2745 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.33 [0.26, 0.41] |
| 1.1 Method of randomisation inappropriate or not reported | 11 | 1457 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.31 [0.23, 0.42] |
| 1.2 Appropriate method of randomisation | 8 | 1288 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.36 [0.26, 0.50] |
| 2 Unit of Analysis for randomisation Show forest plot | 19 | 2745 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.33 [0.26, 0.41] |
| 2.1 Individual patients | 13 | 1681 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.38 [0.29, 0.49] |
| 2.2 Individual legs | 6 | 1064 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.23 [0.15, 0.35] |
| 3 Use of background method of thromboprophylaxis Show forest plot | 19 | 2745 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.33 [0.26, 0.41] |
| 3.1 Trials without background thromboprophylaxis | 9 | 1497 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.38 [0.29, 0.50] |
| 3.2 Trials with background thromboprophylaxis | 10 | 1248 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.25 [0.17, 0.36] |
| 4 Method of diagnosis Show forest plot | 19 | 2745 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.33 [0.26, 0.41] |
| 4.1 Fibrogen uptake test alone | 7 | 1101 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.27 [0.18, 0.39] |
| 4.2 Fibrinogen uptake test & phlebography | 6 | 1013 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.29 [0.19, 0.43] |
| 4.3 Ultrasonography | 2 | 238 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.48 [0.25, 0.94] |
| 4.4 Phlebography | 4 | 393 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.47 [0.29, 0.75] |
