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'Risk of bias' summary: review authors' judgements about allocation concealment for each included study.

Figuras y tablas -
Figure 1

'Risk of bias' summary: review authors' judgements about allocation concealment for each included study.

Comparison 1: House dust mite reduction versus control, Outcome 1: Numbers improved

Figuras y tablas -
Analysis 1.1

Comparison 1: House dust mite reduction versus control, Outcome 1: Numbers improved

Comparison 1: House dust mite reduction versus control, Outcome 2: Asthma symptoms score

Figuras y tablas -
Analysis 1.2

Comparison 1: House dust mite reduction versus control, Outcome 2: Asthma symptoms score

Comparison 1: House dust mite reduction versus control, Outcome 3: Medication usage

Figuras y tablas -
Analysis 1.3

Comparison 1: House dust mite reduction versus control, Outcome 3: Medication usage

Comparison 1: House dust mite reduction versus control, Outcome 4: FEV1 (forced expiratory volume in one second)

Figuras y tablas -
Analysis 1.4

Comparison 1: House dust mite reduction versus control, Outcome 4: FEV1 (forced expiratory volume in one second)

Comparison 1: House dust mite reduction versus control, Outcome 5: PEFR morning (Peak Expiratory Flow Rate)

Figuras y tablas -
Analysis 1.5

Comparison 1: House dust mite reduction versus control, Outcome 5: PEFR morning (Peak Expiratory Flow Rate)

Comparison 1: House dust mite reduction versus control, Outcome 6: PEFR evening (Peak Expiratory Flow Rate)

Figuras y tablas -
Analysis 1.6

Comparison 1: House dust mite reduction versus control, Outcome 6: PEFR evening (Peak Expiratory Flow Rate)

Comparison 1: House dust mite reduction versus control, Outcome 7: PC20 (provocative concentration for 20% fall in FEV1)

Figuras y tablas -
Analysis 1.7

Comparison 1: House dust mite reduction versus control, Outcome 7: PC20 (provocative concentration for 20% fall in FEV1)

Comparison 1. House dust mite reduction versus control

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1.1 Numbers improved Show forest plot

7

338

Risk Ratio (M‐H, Fixed, 95% CI)

1.01 [0.80, 1.27]

1.1.1 Chemical methods

3

138

Risk Ratio (M‐H, Fixed, 95% CI)

0.94 [0.72, 1.24]

1.1.2 Physical methods ‐ parallel‐group studies

1

53

Risk Ratio (M‐H, Fixed, 95% CI)

1.11 [0.70, 1.74]

1.1.3 Physical methods ‐ cross‐over studies

2

98

Risk Ratio (M‐H, Fixed, 95% CI)

1.20 [0.57, 2.54]

1.1.4 Combination methods

1

49

Risk Ratio (M‐H, Fixed, 95% CI)

0.85 [0.21, 3.40]

1.2 Asthma symptoms score Show forest plot

20

1485

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.06 [‐0.16, 0.05]

1.2.1 Chemical methods

4

125

Std. Mean Difference (IV, Fixed, 95% CI)

0.39 [0.04, 0.75]

1.2.2 Physical methods ‐ parallel‐group studies

11

1098

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.09 [‐0.21, 0.03]

1.2.3 Physical methods ‐ cross‐over studies

3

70

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.48 [‐0.97, 0.01]

1.2.4 Combination methods

2

192

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.01 [‐0.29, 0.28]

1.3 Medication usage Show forest plot

11

1115

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.05 [‐0.17, 0.07]

1.3.1 Chemical methods

1

23

Std. Mean Difference (IV, Fixed, 95% CI)

0.89 [0.02, 1.75]

1.3.2 Physical methods ‐ parallel‐group studies

7

1020

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.06 [‐0.19, 0.06]

1.3.3 Physical methods ‐ cross‐over studies

3

72

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.17 [‐0.64, 0.29]

1.4 FEV1 (forced expiratory volume in one second) Show forest plot

15

675

Std. Mean Difference (IV, Fixed, 95% CI)

0.13 [‐0.02, 0.28]

1.4.1 Chemical methods

4

125

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.05 [‐0.41, 0.30]

1.4.2 Physical methods ‐ parallel‐group studies

5

249

Std. Mean Difference (IV, Fixed, 95% CI)

0.25 [‐0.00, 0.51]

1.4.3 Physical methods ‐ cross‐over studies

2

42

Std. Mean Difference (IV, Fixed, 95% CI)

0.07 [‐0.53, 0.68]

1.4.4 Combination methods

4

259

Std. Mean Difference (IV, Fixed, 95% CI)

0.12 [‐0.12, 0.36]

1.5 PEFR morning (Peak Expiratory Flow Rate) Show forest plot

24

1665

Std. Mean Difference (IV, Fixed, 95% CI)

0.01 [‐0.08, 0.11]

1.5.1 Chemical methods

4

125

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.21 [‐0.56, 0.15]

1.5.2 Physical methods ‐ parallel‐group studies

12

1162

Std. Mean Difference (IV, Fixed, 95% CI)

0.02 [‐0.10, 0.13]

1.5.3 Physical methods ‐ cross‐over studies

5

154

Std. Mean Difference (IV, Fixed, 95% CI)

0.06 [‐0.26, 0.37]

1.5.4 Combination methods

3

224

Std. Mean Difference (IV, Fixed, 95% CI)

0.09 [‐0.18, 0.35]

1.6 PEFR evening (Peak Expiratory Flow Rate) Show forest plot

13

467

Std. Mean Difference (IV, Fixed, 95% CI)

0.06 [‐0.13, 0.24]

1.6.1 Chemical methods

2

53

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.49 [‐1.05, 0.07]

1.6.2 Physical methods ‐ parallel‐group studies

6

306

Std. Mean Difference (IV, Fixed, 95% CI)

0.15 [‐0.08, 0.37]

1.6.3 Physical methods ‐ cross‐over studies

4

90

Std. Mean Difference (IV, Fixed, 95% CI)

0.06 [‐0.35, 0.47]

1.6.4 Combination methods

1

18

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.03 [‐0.96, 0.89]

1.7 PC20 (provocative concentration for 20% fall in FEV1) Show forest plot

13

493

Std. Mean Difference (IV, Fixed, 95% CI)

0.05 [‐0.13, 0.22]

1.7.1 Chemical methods

5

147

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.10 [‐0.43, 0.23]

1.7.2 Physical methods, parallel‐group studies

4

130

Std. Mean Difference (IV, Fixed, 95% CI)

0.08 [‐0.27, 0.43]

1.7.3 Physical methods ‐ cross‐over studies

1

18

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.12 [‐1.05, 0.80]

1.7.4 Combination methods

4

198

Std. Mean Difference (IV, Fixed, 95% CI)

0.15 [‐0.13, 0.43]

Figuras y tablas -
Comparison 1. House dust mite reduction versus control