Endovascular repair compared with conventional open surgery for thoracoabdominal aortic aneurysms (TAAA)

Patient or population: people with a diagnosis of thoracoabdominal aortic aneurysm

Settings: hospital

Intervention: endovascular repair

Comparison: open surgical repair

Outcomes

Illustrative comparative risks* (95% CI)

Relative effect
(95% CI)

No of Participants
(studies)

Quality of the evidence
(GRADE)

Comments

Assumed risk

Corresponding risk

Open surgical repair

Endovascular repair

Prevention of aneurysm rupture (defined as number of participants without a rupture)

(5 years)

Aneurysm related mortality

(12 months)

All cause mortality

(5 years)

Spinal cord ischaemia (paraplegia, paraperesis)

(5 years)

Visceral arterial branch compromise causing, mesenteric ischaemia, and renal failure

(5 years)

Rate of reintervention

(5 years)

Conversion to open repair

(5 years)

*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: Confidence interval; RR: Risk ratio.

GRADE Working Group grades of evidence
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: We are very uncertain about the estimate.