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Cochrane Database of Systematic Reviews

Oral paracetamol (acetaminophen) for cancer pain

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Información

DOI:
https://doi.org/10.1002/14651858.CD012637Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 25 abril 2017see what's new
Tipo:
  1. Intervention
Etapa:
  1. Protocol
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Dolor y cuidados paliativos

Copyright:
  1. Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Autores

  • Philip J Wiffen

    Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics), University of Oxford, Oxford, UK

  • Sheena Derry

    Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics), University of Oxford, Oxford, UK

  • R Andrew Moore

    Correspondencia a: Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics), University of Oxford, Oxford, UK

    [email protected]

  • Ewan D McNicol

    Department of Anesthesiology and Perioperative Medicine, Tufts Medical Center, Boston, USA

  • Rae F Bell

    Research Fellow Regional Centre of Excellence in Palliative Care, Haukeland University Hospital, Bergen, Norway

  • Daniel B Carr

    Pain Research, Education and Policy (PREP) Program, Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, USA

  • Mairead McIntyre

    West Hoe Surgery, Plymouth, UK

  • Bee Wee

    Nuffield Department of Medicine and Sir Michael Sobell House, Churchill Hospital, Oxford, UK

Contributions of authors

RAM, SD, and PW drafted the initial protocol, and other authors commented on that draft to produce the final version.

Sources of support

Internal sources

  • Oxford Pain Relief Trust, UK.

    General institutional support

External sources

  • The National Institute for Health Research (NIHR), UK.

    NIHR Cochrane Programme Grant: 13/89/29 ‐ Addressing the unmet need of chronic pain: providing the evidence for treatments of pain

Declarations of interest

PW: none known.

SD: none known.

RAM has received grant support from Grünenthal relating to individual patient‐level analyses of trial data regarding tapentadol in osteoarthritis and back pain (2015). He has received honoraria for attending boards with Menarini concerning methods of analgesic trial design (2014), with Novartis (2014) about the design of network meta‐analyses, and RB on understanding pharmacokinetics of drug uptake (2015). He has received honoraria from Omega Pharma (2016) and Futura Pharma (2016) for providing advice on trial and data analysis methods.

EDM: none known.

RFB: none known.

DBC: none known; DBC is a specialised pain physician and has managed patients with cancer pain.

MM: none known.

BW: none known. BW is a specialist Palliative Medicine Consultant physician and manages patients with advanced life‐threatening illnesses, including cancer.

Acknowledgements

The National Institute for Health Research (NIHR) is the largest single funder of the Cochrane Pain, Palliative and Supportive Care Review Group. Disclaimer: The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the NIHR, National Health Service (NHS), or the Department of Health.

Institutional support was provided by the Oxford Pain Relief Trust.

Version history

Published

Title

Stage

Authors

Version

2017 Jul 12

Oral paracetamol (acetaminophen) for cancer pain

Review

Philip J Wiffen, Sheena Derry, R Andrew Moore, Ewan D McNicol, Rae Frances Bell, Daniel B Carr, Mairead McIntyre, Bee Wee

https://doi.org/10.1002/14651858.CD012637.pub2

2017 Apr 25

Oral paracetamol (acetaminophen) for cancer pain

Protocol

Philip J Wiffen, Sheena Derry, R Andrew Moore, Ewan D McNicol, Rae F Bell, Daniel B Carr, Mairead McIntyre, Bee Wee

https://doi.org/10.1002/14651858.CD012637

Keywords

MeSH

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.