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Cochrane Database of Systematic Reviews

Withdrawal of drug therapy for patients with quiescent Crohn's disease

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Información

DOI:
https://doi.org/10.1002/14651858.CD012540Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 02 febrero 2017see what's new
Tipo:
  1. Intervention
Etapa:
  1. Protocol
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Salud digestiva

Copyright:
  1. Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Autores

  • Ray Boyapati

    Department of Gastroenterology, Monash Health, Clayton, Australia

  • Joana Torres

    Department of Medicine, Division of Gastroenterology, Icahn Medical School of Medicine at Mount Sinai, New York, USA

  • Carolina Palmela

    Division of Gastroenterology, Surgical Department, Hospital Beatriz Ângelo, Loures, Portugal

  • Claire E Parker

    Cochrane IBD Group, Robarts Clinical Trials, London, Canada

  • Orli M Silverberg

    Department of Health Sciences, University of Western Ontario, London, Canada

  • Sonam D Upadhyaya

    Department of Health Sciences, University of Western Ontario, London, Canada

  • Reena Khanna

    Department of Medicine, University of Western Ontario, London, Canada

    Robarts Clinical Trials, London, Canada

  • Vipul Jairath

    Department of Medicine, University of Western Ontario, London, Canada

    Robarts Clinical Trials, London, Canada

    Department of Epidemiology and Biostatistics, University of Western Ontario, London, Canada

  • Brian G Feagan

    Cochrane IBD Group, Robarts Clinical Trials, London, Canada

    Department of Medicine, University of Western Ontario, London, Canada

    Robarts Clinical Trials, London, Canada

    Department of Epidemiology and Biostatistics, University of Western Ontario, London, Canada

  • Jean‐Frédéric Colombel

    Correspondencia a: Department of Medicine, Division of Gastroenterology, Icahn Medical School of Medicine at Mount Sinai, New York, USA

    [email protected]

Declarations of interest

Ray Boyapati: has no known conflicts of interest.

Joana Torres: has received fees from Takeda for consultancy; and fees for travel, accommodation or meeting expenses from AbbVie and Ferring. All of these activities are outside the submitted work.

Carolina Palmela: has no known conflicts of interest.

Claire E Parker: has no known conflicts of interest.

Orli M Silverberg: has no known conflicts of interest.

Sonam D Upadhyaya: has no known conflicts of interest.

Reena Khanna: has received consulting fees from AbbVie, Janssen, Pfizer, Shire, and Takeda. All of these activities are outside the submitted work.

Vipul Jairath: has received scientific advisory board fees from Abbvie, Sandoz, Ferring and Janssen; speaker's fees from Takeda and Ferring; and travel support for conference attendance from Vifor pharmaceuticals. All of these activities are outside the submitted work.

Brian G Feagan: has received fee(s) from Abbott/AbbVie, Amgen, Astra Zeneca, Avaxia Biologics Inc., Bristol‐Myers Squibb, Celgene, Centocor Inc., Elan/Biogen, Ferring, JnJ/Janssen, Merck, Novartis, Novonordisk, Pfizer, Prometheus Laboratories, Protagonist, Salix Pharma, Takeda, Teva, Tillotts Pharma AG, UCB Pharma for Board membership; fee(s) from Abbott/AbbVie, Actogenix, Albireo Pharma, Amgen, Astra Zeneca, Avaxia Biologics Inc., Axcan, Baxter Healthcare Corp., Boehringer‐Ingelheim, Bristol‐Myers Squibb, Calypso Biotech, Celgene, Elan/Biogen, EnGene, Ferring Pharma, Roche/Genentech, GiCare Pharma, Gilead, Given Imaging Inc., GSK, Ironwood Pharma, Janssen Biotech (Centocor), JnJ/Janssen, Kyowa Kakko Kirin Co Ltd., Lexicon, Lilly, Merck, Millennium, Nektar, Novonordisk, Pfizer, Prometheus Therapeutics and Diagnostics, Protagonist, Receptos, Salix Pharma, Serono, Shire, Sigmoid Pharma, Synergy Pharma Inc., Takeda, Teva Pharma, Tillotts, UCB Pharma, Vertex Pharma, Warner‐Chilcott, Wyeth, Zealand, and Zyngenia for consultancy; and lecture fee(s) from: Abbott/AbbVie, JnJ/Janssen, Takeda, Warner‐Chilcott, and UCB Pharma. All of these activities are outside the submitted work.

Jean‐Frédéric Colombel has received consulting fees from Abbvie, Amgen, Boehringer‐Ingelheim, Celgene Corporation, Celltrion, Eli Lilly, Enterome, Ferring, Genentech, Janssen Pharmaceuticals, Medimmune, Merck &Co, Pfizer, Protagonist, Second Genome, Seres, Shire, Takdea, Theradiag and Theravance Biopharma; grants/grants pending from Abbvie, Takeda, Janssen Pharmaceuticals; payment for lectures and speakers bureaus from AbbVie, Ferring, Pfizer, Takeda and Shire; and stock/stock options from Intestinal Biotech Development and Genfit. All of these activities are outside the submitted work.

Acknowledgements

Partial funding for the Cochrane IBD Group (April 1, 2016 ‐ March 31, 2018) has been provided by Crohn's and Colitis Canada (CCC).

Version history

Published

Title

Stage

Authors

Version

2018 May 12

Withdrawal of immunosuppressant or biologic therapy for patients with quiescent Crohn's disease

Review

Ray K Boyapati, Joana Torres, Carolina Palmela, Claire E Parker, Orli M Silverberg, Sonam D Upadhyaya, Tran M Nguyen, Jean‐Frédéric Colombel

https://doi.org/10.1002/14651858.CD012540.pub2

2017 Feb 02

Withdrawal of drug therapy for patients with quiescent Crohn's disease

Protocol

Ray Boyapati, Joana Torres, Carolina Palmela, Claire E Parker, Orli M Silverberg, Sonam D Upadhyaya, Reena Khanna, Vipul Jairath, Brian G Feagan, Jean‐Frédéric Colombel

https://doi.org/10.1002/14651858.CD012540

Keywords

MeSH

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.