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Yoga para la rehabilitación del accidente cerebrovascular

Appendices

Appendix 1. CENTRAL search strategy

#1 stroke

#2 yoga

#3 meditation

#4 mind body therapy

#5 breathing exercises

#6 relaxation

#7 #2 or #3 or #4 or #5 or #6

#8 #1 and #7

Appendix 2. MEDLINE search strategy

MEDLINE (Ovid)

1. cerebrovascular disorders/ or exp basal ganglia cerebrovascular disease/ or exp brain ischemia/ or exp carotid artery diseases/ or exp intracranial arterial diseases/ or exp intracranial arteriovenous malformations/ or exp "intracranial embolism and thrombosis"/ or exp intracranial hemorrhages/ or stroke/ or exp brain infarction/ or vasospasm, intracranial/ or vertebral artery dissection/

2. (stroke or poststroke or post‐stroke or cerebrovasc$ or brain vasc$ or cerebral vasc$ or cva$ or apoplex$ or SAH).tw.

3. ((brain$ or cerebr$ or cerebell$ or intracran$ or intracerebral) adj5 (isch?emi$ or infarct$ or thrombo$ or emboli$ or occlus$)).tw.

4. ((brain$ or cerebr$ or cerebell$ or intracerebral or intracranial or subarachnoid) adj5 (haemorrhage$ or hemorrhage$ or haematoma$ or hematoma$ or bleed$)).tw.

5. hemiplegia/ or exp paresis/ or exp Gait Disorders, Neurologic/

6. (hemipleg$ or hemipar$ or pareis or paretic).tw.

7. 1 or 2 or 3 or 4 or 5 or 6

8. Yoga/ or mind‐body therapies/ or exp breathing exercises/ or meditation/ or relaxation therapy/

9. (yoga$ or yogic or relaxation or meditation or mind‐body or (mind adj1 body) or postures).tw.

10. (breath$ adj3 (exercises or control$)).tw.

11. (hatha or ashtanga or bikram or iyengar or kripalu or kundalini or sivananda or vinyasa or raja or radja or bhakti or jnana or kriya or karma or yama or niyama or asana$ or pranayama or pratyahara or dharana or dhyana or samadhi or bandha or mudra).tw.

12. 8 or 9 or 10 or 11

13. 7 and 12

14. Randomized Controlled Trials as Topic/

15. random allocation/

16. Controlled Clinical Trials as Topic/

17. control groups/

18. clinical trials as topic/

19. double‐blind method/

20. single‐blind method/

21. Placebos/

22. placebo effect/

23. cross‐over studies/

24. randomized controlled trial.pt.

25. controlled clinical trial.pt.

26. clinical trial.pt.

27. (random$ or RCT or RCTs).tw.

28. (controlled adj5 (trial$ or stud$)).tw.

29. (clinical$ adj5 trial$).tw.

30. ((control or treatment or experiment$ or intervention) adj5 (group$ or subject$ or patient$)).tw.

31. (quasi‐random$ or quasi random$ or pseudo‐random$ or pseudo random$).tw.

32. ((control or experiment$ or conservative) adj5 (treatment or therapy or procedure or manage$)).tw.

33. ((singl$ or doubl$ or tripl$ or trebl$) adj5 (blind$ or mask$)).tw.

34. (cross‐over or cross over or crossover).tw.

35. (placebo$ or sham).tw.

36. trial.ti.

37. (assign$ or allocat$).tw.

38. controls.tw.

39. or/14‐38

40. 13 and 39

41. exp animals/ not humans.sh.

42. 40 not 41

Appendix 3. Embase search strategy

Embase (Ovid)

1. cerebrovascular disorders/ or exp basal ganglia cerebrovascular disease/ or exp brain ischemia/ or exp carotid artery diseases/ or exp intracranial arterial diseases/ or exp intracranial arteriovenous malformations/ or exp "intracranial embolism and thrombosis"/ or exp intracranial hemorrhages/ or stroke/ or exp brain infarction/ or vasospasm, intracranial/ or vertebral artery dissection/

2. (stroke or poststroke or post‐stroke or cerebrovasc$ or brain vasc$ or cerebral vasc$ or cva$ or apoplex$ or SAH).tw.

3. ((brain$ or cerebr$ or cerebell$ or intracran$ or intracerebral) adj5 (isch?emi$ or infarct$ or thrombo$ or emboli$ or occlus$)).tw.

4. ((brain$ or cerebr$ or cerebell$ or intracerebral or intracranial or subarachnoid) adj5 (haemorrhage$ or hemorrhage$ or haematoma$ or hematoma$ or bleed$)).tw.

5. hemiplegia/ or exp paresis/ or exp Gait Disorders, Neurologic/

6. (hemipleg$ or hemipar$ or pareis or paretic).tw.

7. 1 or 2 or 3 or 4 or 5 or 6

8. Yoga/ or mind‐body therapies/ or exp breathing exercises/ or meditation/ or relaxation therapy/

9. (yoga$ or yogic or relaxation or meditation or mind‐body or (mind adj1 body) or postures).tw.

10. (breath$ adj3 (exercises or control$)).tw.

11. (hatha or ashtanga or bikram or iyengar or kripalu or kundalini or sivananda or vinyasa or raja or radja or bhakti or jnana or kriya or karma or yama or niyama or asana$ or pranayama or pratyahara or dharana or dhyana or samadhi or bandha or mudra).tw.

12. 8 or 9 or 10 or 11

13. 7 and 12

14. Randomized Controlled Trials as Topic/

15. random allocation/

16. Controlled Clinical Trials as Topic/

17. control groups/

18. clinical trials as topic/

19. double‐blind method/

20. single‐blind method/

21. Placebos/

22. placebo effect/

23. cross‐over studies/

24. randomized controlled trial.pt.

25. controlled clinical trial.pt.

26. clinical trial.pt.

27. (random$ or RCT or RCTs).tw.

28. (controlled adj5 (trial$ or stud$)).tw.

29. (clinical$ adj5 trial$).tw.

30. ((control or treatment or experiment$ or intervention) adj5 (group$ or subject$ or patient$)).tw.

31. (quasi‐random$ or quasi random$ or pseudo‐random$ or pseudo random$).tw.

32. ((control or experiment$ or conservative) adj5 (treatment or therapy or procedure or manage$)).tw.

33. ((singl$ or doubl$ or tripl$ or trebl$) adj5 (blind$ or mask$)).tw.

34. (cross‐over or cross over or crossover).tw.

35. (placebo$ or sham).tw.

36. trial.ti.

37. (assign$ or allocat$).tw.

38. controls.tw.

39. or/14‐38

40. 13 and 39

41. exp animals/ not humans.sh.

42. 40 not 41

Appendix 4. CINAHL search strategy

CINAHL (EBSCO)

S39. S13 AND S38; Limiters ‐ Human; Randomized Controlled Trials

S38. S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35 OR S36 OR S37

S37. TX controls

S36. TX (assign* OR allocat*)

S35. TI trial

S34. TX (placebo* OR sham)

S33. TX (cross‐over OR cross over ORcrossover)

S32. TX ((singl* OR doubl* OR tripl* OR trebl*) W5 (blind* OR mask*))

S31. TX ((control OR experiment* OR conservative) W5 (treatment OR therapy OR procedure OR manage*))

S30. TX (quasi‐random* OR quasi random* OR pseudo‐random* OR pseudo random*)

S29. TX ((control OR treatment OR experiment* OR intervention) W5 (group* OR subject* OR patient*))

S28. TX (clinical* W5 trial*)

S27. TX ((controlled W5 (trial* OR stud*))

S26. TX (random* OR RCT OR RCTs)

S25. PT Clinical Trial

S24. PT Controlled Clinical Trial

S23. PT Randomized Controlled Trial

S22. (MH "Crossover Design")

S21. (MH "Placebo Effect")

S20. (MH "Placebos")

S19. (MH "Single‐Blind Studies")

S18. (MH "Double‐Blind Studies")

S17. (MH "Control Group")

S16. (MH "Clinical Trials")

S15. (MH "Random Assignment")

S14. (MH "Randomized Controlled Trials")

S13. S7 AND S12

S12. S8 OR S9 OR S10 OR S11

S11. TX (hatha OR ashtanga OR bikram OR iyengar OR kripalu OR kundalini OR sivananda OR vinyasa OR raja OR radja OR bhakti OR jhana OR kriya OR karma OR yama OR niyama OR asana* OR pranayama OR pratyahara OR dharana OR dhyana OR samadhi OR bandha OR mudra)

S10. TX ((breath* W3 (exercises OR control*))

S9. TX ((yoga* OR yogic OR relaxation OR meditation OR mindbody OR (mind W1 body) OR postures))

S8. (MH "Yoga") OR (MH "Mind‐body Therapies") OR (MH "Breathing Exercises+") OR (MH "Meditation") OR (MH "Relaxation Therapy")

S7. S1 OR S2 OR S3 OR S4 OR S5 OR S6

S6. TX (hemipleg* OR hemipar* OR pareis OR paretic)

S5. (MH "Hemiplegia") OR (MH "Paresis+") OR (MH "Gait Disorders, Neurologic+")

S4. S4 TX ((brain* OR cerebr* OR cerebell* OR intracerebral OR intracranial OR subarachnoid) W5 (haemorrhage* OR hemorrhage* OR haematoma* OR hematoma OR bleed*))

S3. TX ((brain* OR cerebr* OR cerebell* OR intracran* OR intracerebral) W5 (isch?emi* OR infarct* OR thrombo* OR emboli* OR occlus*))

S2. TX (stroke OR poststroke OR poststroke OR cerebrovasc* OR brain vasc* OR cerebral vasc* OR cva* OR apoplex* OR SAH)

S1. (MH "Cerebrovascular Disorders") OR (MH"Basal Ganglia Cerebrovascular Disease+") OR (MH "Brain Ischemia+") OR (MH "Carotid Artery Diseases+") OR (MH "Intracranial Arterial Diseases+") OR (MH "Intracranial Arteriovenous Malformations+") OR (MH ""Intracranial Embolism and Thrombosis"+") OR (MH "Intracranial Hemorrhages+") OR (MH "Stroke") OR (MH "Brain Infarction+") OR (MH "Vasospasm, Intracranial") OR (MH "Vertebral Artery Dissection")

Appendix 5. PsycINFO search strategy

Stroke (anywhere)

Yoga (anywhere)

Meditation (anywhere)

Relaxation

Breathing exercises

Mind body therapy

Stroke AND yoga

Stroke AND meditation

Stroke AND relaxation

Stroke AND breathing exercises

Stroke AND mind body therapy

Yoga OR mind‐body therapy OR breathing exercises OR meditation OR relaxation therapy

Stroke AND (Yoga OR mind‐body therapy OR breathing exercises OR meditation OR relaxation therapy)

Appendix 6. AMED search strategy

S40. S13 AND S39

S39. S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35 OR S36 OR S37 OR S38TX controls

S38. TX controls

S37. TX (assign* OR allocat*)

S36. TI trial

S35. TX (placebo* OR sham)

S34. TX (cross‐over OR cross over OR crossover)

S33. TX ((singl* OR doubl* OR tripl* OR trebl*) W5 (blind* OR mask*))

S32. TX ((control OR experiment* OR conservative) W5 (treatment OR therapy OR procedure OR manage*))

S31. TX (quasi‐random* OR quasi random* OR pseudo‐random* OR pseudo random*)

S30. TX ((control OR treatment OR experiment* OR intervention) W5 (group* OR subject* OR patient*))

S29. TX (clinical* W5 trial*)

S28. TX ((controlled W5 (trial* OR stud*))

S27. TX (random* OR RCT OR RCTs)

S26. PT Clinical Trial

S25. PT Controlled Clinical Trial

S24. PT Randomized Controlled Trial

S23. cross‐over studies/

S22. placebo effect/

S21. Placebos/

S20. single‐blind method/

S19. double‐blind method/

S18. clinical trials as topic/

S17. control groups/

S16. Controlled Clinical Trials as Topic/

S15. random allocation/

S14. Randomized Controlled Trials as Topic/

S13. S7 AND S12

S12. S8 OR S9 OR S10 OR S11

S11. TX (hatha OR ashtanga OR bikram OR iyengar OR kripalu OR kundalini
OR sivananda OR vinyasa OR raja OR radja OR bhakti OR jhana OR kriya OR karma OR yama OR niyama OR asana* OR pranayama OR pratyahara OR dharana OR dhyana OR samadhi OR bandha OR mudra)

S10. TX ((breath* W3 (exercises OR control*))

S9. TX ((yoga* OR yogic OR relaxation OR meditation OR mindbody OR (mind W1 body) OR postures))

S8. Yoga/ or mind‐body therapies/ or exp breathing exercises/ or meditation/ or relaxation therapy/

S7. S1 OR S2 OR S3 OR S4 OR S5 OR S6

S6. TX (hemipleg* OR hemipar* OR pareis OR paretic)

S5. hemiplegia/ or exp paresis/ or exp Gait Disorders, Neurologic/

S4. TX ((brain* OR cerebr* OR cerebell* OR intracerebral OR intracranial OR subarachnoid) W5 (haemorrhage* OR hemorrhage* OR haematoma* OR hematoma* OR bleed*))

S3. TX ((brain* OR cerebr* OR cerebell* OR intracran* OR intracerebral) W5 (isch?emi* OR infarct* OR thrombo* OR emboli* OR occlus*))

S2. TX (stroke OR poststroke OR poststroke OR cerebrovasc* OR brain vasc* OR cerebral vasc* OR cva* OR apoplex* OR SAH)

S1. cerebrovascular disorders/ or exp basal ganglia cerebrovascular disease/ or exp brain ischemia/ or exp carotid artery diseases/ or exp intracranial arterial diseases/ or exp intracranial arteriovenous malformations/ or exp "intracranial embolism and thrombosis"/ or exp intracranial hemorrhages/ or stroke/ or exp brain infarction/ or vasospasm, intracranial/ or vertebral artery dissection/

Appendix 7. LILACS search strategy

1. (mh:(cerebrovascular disORders)) OR (mh:(basal ganglia cerebrovascular disease)) OR (mh:(brain ischemia)) OR (mh:(carotid artery diseases)) OR (mh:(intracranial arterial diseases)) OR (mh:(intracranial arteriovenous malfORmations)) OR (mh:(intracranial embolism and thrombosis)) OR (mh:(intracranial hemORrhages)) OR (mh:(stroke)) OR (mh:(brain infarction)) OR (mh:(intracranial vasospasm)) OR (mh:(vertebral artery dissection))

2. (tw:(stroke)) OR (tw:(poststroke)) OR (tw:(post‐stroke)) OR (tw:(cerebrovasc$)) OR (tw:(brain vasc$)) OR (tw:(cerebral vasc$)) OR (tw:(cva$)) OR (tw:(apoplex$)) OR (tw:(SAH))

3. (tw:(brain$)) OR (tw:(cerebr$)) OR (tw:(cerebell$)) OR (tw:(intracran$)) OR (tw:(intracerebral)) adj5 (tw:(isch?emi$)) OR (tw:(infarct$)) OR (tw:(thrombo$)) OR (tw:(emboli$)) OR (tw:(occlus$))

4. (tw:(brain$)) OR (tw:(cerebr$)) OR (tw:(cerebell$)) OR (tw:(intracerebral)) OR (tw:(intracranial)) OR (tw:(subarachnoid)) adj5 (tw:(haemorrhage$)) OR (tw:(hemorrhage$)) OR (tw:(haematoma$)) OR (tw:(hematoma$)) OR (tw:(bleed$))

5. (mh:(hemiplegia OR (mh:(paresis OR (mh:(”Gait DisORders, Neurologic”)

6. (tw:(hemipleg$)) OR (tw:(hemipar$)) OR (tw:(pareis)) OR (tw:(paretic))

7. 1 OR 2 OR 3 OR 4 OR 5 OR 6

8. (mh:(Yoga)) OR (mh:(mind‐body therapies)) OR (mh:(breathing exercises)) OR (mh:(meditation)) OR (mh:(relaxation therapy))

9. (tw:(yoga$)) OR (tw:(yogic)) OR (tw:(relaxation)) OR (tw:(meditation)) OR (tw:(mind‐body)) OR (tw:(mind)) adj1 (tw:(body)) OR (tw:(postures))

10. (tw:(breath$)) adj3 (tw:(exercises)) OR (tw:(control$))

11. (tw:(hatha)) OR (tw:(ashtanga)) OR (tw:(bikram)) OR (tw:(iyengar)) OR (tw:(kripalu)) OR (tw:(kundalini)) OR (tw:(sivananda)) OR (tw:(vinyasa)) OR (tw:(raja)) OR (tw:(radja)) OR (tw:(bhakti)) OR (tw:(jnana)) OR (tw:(kriya)) OR (tw:(karma)) OR (tw:(yama)) OR (tw:(niyama)) OR (tw:(asana$)) OR (tw:(pranayama)) OR (tw:(pratyahara)) OR (tw:(dharana)) OR (tw:(dhyana)) OR (tw:(samadhi)) OR (tw:(bandha)) OR (tw:(mudra))

12. 8 OR 9 OR 10 OR 11

13. 7 and 12

14. (mh:(Randomized Controlled Trials))

15. (mh:(random allocation))

16. (mh:(Controlled Clinical Trials))

17. (mh:(control groups))

18. (mh:(clinical trials))

19. (mh:(double‐blind method))

20. (mh:(single‐blind method))

21. (mh:(Placebos))

22. (mh:(placebo effect))

23. (mh:(cross‐over studies))

24. (pt:(randomized controlled trial))

25. (pt:(controlled clinical trial))

26. (pt:(clinical trial))

27. (tw:(random$ ))OR (tw:(RCT)) OR (tw:(RCTs))

28. (tw:(controlled)) adj5 (tw:(trial$)) OR (tw:(stud$))

29. (tw:(clinical$)) adj5 (tw:(trial$))

30. (tw:(control)) OR (tw:(treatment)) OR (tw:(experiment$)) OR (tw:(intervention)) adj5 (tw:(group$)) OR (tw:(subject$)) OR (tw:(patient$))

31. (tw:(quasi‐random$)) OR (tw:(quasi random$)) OR (tw:(pseudo‐random$)) OR (tw:(pseudo random$))

32. (tw:(control)) OR (tw:(experiment$)) OR (tw:(conservative)) adj5 (tw:(treatment)) OR (tw:(therapy)) OR (tw:(procedure)) OR (tw:(manage$))

33. (tw:(singl$)) OR (tw:(doubl$)) OR (tw:(tripl$)) OR (tw:(trebl$)) adj5 (tw:(blind$)) OR (tw:(mask$))

34. (tw:(cross‐over)) OR (tw:(crossover))

35. (tw:(placebo$)) OR (tw:(sham))

36. (ti:(trial))

37. (tw:(assign$)) OR (tw:(allocat$))

38. (tw:(controls))

39. OR/14‐38

40. 13 and 39

41. (mh:(animals)) NOT (mh:(humans))

42. 40 not 41

Appendix 8. SciELO search strategy

1. transtornos cerebrovasculares/ OR exp doença cerebrovascular dos gânglios da base/ OR exp isquemia encefálica/ OR exp doenças das artérias carótidas/ OR traumatismo cerebrovascular/ OR exp doenças arteriais intracranianas/ OR exp “embolia intracraniana e trombólise”/ OR exp hemorragias intracranianas/ OR acidente vascular cerebral/ OR exp infarto encefálico/

2. (acidente$ vascular$ cerebra$ OR pós‐acidente$ vascular$ cerebra$ OR pós acidente$ vascular$ cerebra$ OR AVC$).tw.

3. ((cerebrovascular OR cerebral vascular) adj3 (acidente?)).tw.

4. ((c?rebr$ OR enc?f?lic$ OR vertebrobasilar) adj5 (infart$ OR isquemi$ OR trombo$ OR apoplexia$ OR emboli$)).tw.

5. ((c?rebr$ OR subaracn?id$) adj5 (hemorr?g$ OR hematoma$ OR sangramento)).tw.

6. ((trauma$ OR adquirido$) adj5 les$ cerebr$).tw.

7. lesões cerebrais/ OR exp concussão encefálica / OR exp hemorragia cerebral, traumática/ OR lesão cerebral, crônica/

8. Dano Cerebral, Crônico/

9. trauma craniocerebral/ OR trauma cranioencefálico/OR exp hemorragia intracraniana, traumática/

10. exp encefalite/ OR exp meningite, viral/

11. (encefalite OR meningite).tw.

12. abscesso cerebral/ OR exp infecções do sistema nervosa central/

13. (abscesso cerebral OR infecç$ cerebr$ OR infecç$ encefálic$).tw.

14. OR/1‐13

15. ioga/ or exp “yoga”/

16. “asana”/ or exp “ásana”/

17. “pranayama”

18. dhyana or exp “dyana”/

19. dharma

20. meditação

21. relaxamento

22. “controle da respiração”

23. “posturas”

24. OR/15‐23

25. 14 AND 24

Appendix 9. IndMED search strategy

Stroke AND yoga

Stroke AND mind body therapy

Stroke AND breathing exercises

Stroke AND relaxation

Stroke AND meditation

Appendix 10. OTseeker search strategy

Stroke AND yoga

Stroke AND mind body therapy

Stroke AND breathing exercises

Stroke AND relaxation

Stroke AND meditation

cerebrovascular disorder AND yoga

cerebrovascular disorder AND mind body therapy

cerebrovascular disorder AND breathing exercises

cerebrovascular disorder AND relaxation

cerebrovascular disorder AND meditation

hemiplegia AND yoga

hemiplegia AND mind body therapy

hemiplegia AND breathing exercises

hemiplegia AND relaxation

hemiplegia AND meditation

Appendix 11. PEDro search strategy

Stroke AND yoga

Stroke AND mind body therapy

Stroke AND breathing exercises

Stroke AND relaxation

Stroke AND meditation

Appendix 12. US National Institutes of Health Ongoing Trials Register ClinicalTrials.gov

Stroke AND mind‐body

Stroke AND breathing exercises

Stroke AND relaxation

Stroke AND meditation

Stroke AND yoga

Appendix 13. Stroke Trials Registry

Stroke AND mind‐body

Stroke AND breathing exercises

Stroke AND relaxation

Stroke AND meditation

Stroke AND yoga

Appendix 14. ISRCTN registry

Stroke AND mind‐body

Stroke AND breathing exercises

Stroke AND relaxation

Stroke AND meditation

Stroke AND yoga

Appendix 15. World Health Organization (WHO) International Clinical Trials Registry Platform

Stroke AND mind‐body

Stroke AND breathing exercises

Stroke AND relaxation

Stroke AND meditation

Stroke AND yoga

Study flow diagram.
Figuras y tablas -
Figure 1

Study flow diagram.

'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
Figuras y tablas -
Figure 2

'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.

'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.
Figuras y tablas -
Figure 3

'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.

Comparison 1 Yoga and waitlist control, Outcome 1 Quality of life.
Figuras y tablas -
Analysis 1.1

Comparison 1 Yoga and waitlist control, Outcome 1 Quality of life.

Comparison 1 Yoga and waitlist control, Outcome 2 Balance: Berg Balance Scale.
Figuras y tablas -
Analysis 1.2

Comparison 1 Yoga and waitlist control, Outcome 2 Balance: Berg Balance Scale.

Comparison 1 Yoga and waitlist control, Outcome 3 Balance confidence.
Figuras y tablas -
Analysis 1.3

Comparison 1 Yoga and waitlist control, Outcome 3 Balance confidence.

Comparison 1 Yoga and waitlist control, Outcome 4 Gait (comfortable gait speed).
Figuras y tablas -
Analysis 1.4

Comparison 1 Yoga and waitlist control, Outcome 4 Gait (comfortable gait speed).

Comparison 1 Yoga and waitlist control, Outcome 5 Motor Assessment (Motor Assessment Scale).
Figuras y tablas -
Analysis 1.5

Comparison 1 Yoga and waitlist control, Outcome 5 Motor Assessment (Motor Assessment Scale).

Comparison 1 Yoga and waitlist control, Outcome 6 Walk distance (2‐Minute Walk Distance).
Figuras y tablas -
Analysis 1.6

Comparison 1 Yoga and waitlist control, Outcome 6 Walk distance (2‐Minute Walk Distance).

Comparison 1 Yoga and waitlist control, Outcome 7 Fear of falling.
Figuras y tablas -
Analysis 1.7

Comparison 1 Yoga and waitlist control, Outcome 7 Fear of falling.

Comparison 1 Yoga and waitlist control, Outcome 8 Range of movement.
Figuras y tablas -
Analysis 1.8

Comparison 1 Yoga and waitlist control, Outcome 8 Range of movement.

Comparison 1 Yoga and waitlist control, Outcome 9 Strength.
Figuras y tablas -
Analysis 1.9

Comparison 1 Yoga and waitlist control, Outcome 9 Strength.

Comparison 1 Yoga and waitlist control, Outcome 10 Endurance.
Figuras y tablas -
Analysis 1.10

Comparison 1 Yoga and waitlist control, Outcome 10 Endurance.

Comparison 1 Yoga and waitlist control, Outcome 11 Pain.
Figuras y tablas -
Analysis 1.11

Comparison 1 Yoga and waitlist control, Outcome 11 Pain.

Comparison 1 Yoga and waitlist control, Outcome 12 Disability.
Figuras y tablas -
Analysis 1.12

Comparison 1 Yoga and waitlist control, Outcome 12 Disability.

Comparison 1 Yoga and waitlist control, Outcome 13 Depression: Geriatric Depression Scale (GDS15).
Figuras y tablas -
Analysis 1.13

Comparison 1 Yoga and waitlist control, Outcome 13 Depression: Geriatric Depression Scale (GDS15).

Comparison 1 Yoga and waitlist control, Outcome 14 State Trait Anxiety (STAI‐Y1).
Figuras y tablas -
Analysis 1.14

Comparison 1 Yoga and waitlist control, Outcome 14 State Trait Anxiety (STAI‐Y1).

Comparison 1 Yoga and waitlist control, Outcome 15 Trait Anxiety Inventory (STAI‐Y2).
Figuras y tablas -
Analysis 1.15

Comparison 1 Yoga and waitlist control, Outcome 15 Trait Anxiety Inventory (STAI‐Y2).

Yoga compared with waiting‐list control (yoga) for stroke

Patient or population: adults with stroke

Settings: community

Intervention: yoga

Comparison: wait‐list control (yoga)

Outcomes

Illustrative comparative risks* (95% CI)

Relative effect
(95% CI)

No of Participants
(studies)

Quality of the evidence
(GRADE)

Comments

Assumed risk

Corresponding risk

Waiting‐list control (yoga)

Yoga

Quality of life: Stroke Impact Scale (SIS)

SIS measures quality of life across five domains: physical (strength, hand‐function, mobility, activities of daily living), emotion, memory, communication, social participation, plus 1 global question about stroke recovery. Each dimension is scored on a 100‐point scale; the higher the score, the higher the quality of life

Baseline and post‐intervention

One study: the mean Stroke Recovery Domain in the control group was 63.0

The mean Stroke Recovery Domain in the intervention group was 2.0 higher

22
(1)

⊕⊕⊝⊝
very low

The quality of evidence was graded as very low due to small sample size, incomplete data, and the small number of studies i.e.1

Quality of life: Stroke‐specific QoL Scale (SS QoL)

The Stroke‐specific QoL Scale measures quality of life across 12 domains (49 items): self‐care, vision, language, mobility, work, upper extremity, thinking, personality, mood, family, social, and energy

Each item is scored on a 5‐point Likert scale; the higher the score, the higher the quality of life (score 0‐245)

Baseline and post‐intervention

One study: the mean SS QoL in the control group was 33.0

The mean SS QoL in the intervention group was 2.8 higher

47

(1)

⊕⊕⊝⊝
very low

The quality of evidence was graded as very low due to small sample size, incomplete data, and the small number of studies i.e.1

Balance: Berg Balance Scale (BBS)

14‐item physical performance measure of static and dynamic balance (score: 0‐56)

Baseline and post‐intervention

Two studies: the mean BBS ranged across control groups from 43.8‐48.5

The mean BBS in the intervention groups was 2.4 higher (2.2, 2.5)

69
(2)

⊕⊝⊝⊝
very low

The quality of the evidence was graded as very low due to high risk of bias in relation to sample size, incomplete data, and unrepresentative sample, across the 2 studies

Gait: Comfortable Gait Speed (CGS)

Gait measured over 7 metres (3 repetitions; average time calculated)

Baseline and post‐intervention

One study: the mean CGS in the control group was 0.88

The mean CGS in the intervention group was 1.32 higher

22
(1)

⊕⊕⊝⊝
very low

The quality of evidence was graded as very low due to small sample size, and incomplete data

Depression: Geriatric Depression Scale (GDS15)

A 15‐item self‐report assessment used to identify depression in the elderly. A yes/no response is required for each item (score 0 or 1). Cummulative score: 0‐4 normal, 5‐9 Mild depression, 10‐15 More severe depression

Baseline and post‐intervention

One study: the mean GDS15 in the control group was
4.8

The mean GDS15 in the intervention group was 2.1
lower

22
(1)

⊕⊝⊝⊝
very low

The quality of evidence was graded as very low due to small sample size, incomplete data, and the small number of studies

Anxiety: State Trait Anxiety (STAI‐Y1)

A 40‐item, self‐report assessment of anxiety affect. State anxiety can be defined as fear, nervousness, discomfort, and the arousal of the autonomic nervous system induced temporarily by situations perceived as dangerous. Score 20‐80; higher scores suggest higher levels of anxiety

Baseline and post‐intervention

One study: the mean STAI‐Y1 in the control group was
41.8

The mean STAI‐Y1 in the intervention groups was
8.4 lower

22
(1)

⊕⊝⊝⊝
very
low

The quality of evidence was graded as very low due to small sample size, incomplete data, and the small number of studies

Anxiety: Trait Anxiety Inventory (STAI‐Y2)

A 40‐item, self‐report assessment of anxiety affect. Trait anxiety can be defined as a relatively enduring disposition to feel stress, worry, and discomfort. Score 20‐80; higher scores suggest higher levels of anxiety

Baseline and post‐intervention

One study: the mean STAI‐Y2 in the control group was 42

The mean STAI‐Y2 in the intervention groups was 4.7 lower

22
(1)

⊕⊝⊝⊝
very low

The quality of evidence was graded as very low due to small sample size, incomplete data, and the small number of studies

Disability: modified Rankin Scale (mRS)

A measure of disability, with 6 categories: 0 (no symptoms), 1 (no significant disability), 2 (slight disability), 3 (moderate disability), 4 (moderately severe disability), 5 (severe disability), 6 (dead); reported as dependent/independent

Baseline and post‐intervention

One study: 50% (n = 5) of the control group were 'independent'

In the intervention group the odds of being 'independent' were higher OR 2.08, 95% CI 0.50 to 8.60 (68%; n = 25)

47
(1)

⊕⊝⊝⊝
very low

The quality of evidence was graded as very low due to small sample size, incomplete data, and unrepresentative sample

Adverse events

Post‐intervention

No data

No data

⊕⊝⊝⊝
very low

No evidence available

*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: Confidence interval; OR: Odds Ratio

GRADE Working Group grades of evidence
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: We are very uncertain about the estimate.

Figuras y tablas -
Comparison 1. Yoga and waitlist control

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Quality of life Show forest plot

2

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

1.1 SIS: Physical domain

1

22

Mean Difference (IV, Fixed, 95% CI)

5.20 [‐12.28, 22.68]

1.2 SIS: Emotion domain

1

22

Mean Difference (IV, Fixed, 95% CI)

6.80 [‐8.55, 22.15]

1.3 SIS: Memory domain

1

22

Mean Difference (IV, Fixed, 95% CI)

15.30 [1.29, 29.31]

1.4 SIS: Communication domain

1

22

Mean Difference (IV, Fixed, 95% CI)

1.40 [‐9.45, 12.25]

1.5 SIS: Social participation domain

1

22

Mean Difference (IV, Fixed, 95% CI)

16.10 [‐6.79, 38.99]

1.6 SIS: Stroke recovery domain

1

22

Mean Difference (IV, Fixed, 95% CI)

2.0 [‐17.70, 21.70]

1.7 Stroke‐specific QoL scale

1

47

Mean Difference (IV, Fixed, 95% CI)

2.80 [‐2.03, 7.63]

2 Balance: Berg Balance Scale Show forest plot

2

69

Mean Difference (IV, Fixed, 95% CI)

2.38 [‐1.41, 6.17]

3 Balance confidence Show forest plot

1

47

Mean Difference (IV, Fixed, 95% CI)

10.60 [‐7.08, 28.28]

4 Gait (comfortable gait speed) Show forest plot

1

22

Mean Difference (IV, Fixed, 95% CI)

1.32 [‐1.35, 3.99]

5 Motor Assessment (Motor Assessment Scale) Show forest plot

1

22

Mean Difference (IV, Fixed, 95% CI)

‐4.0 [‐12.42, 4.42]

6 Walk distance (2‐Minute Walk Distance) Show forest plot

1

22

Mean Difference (IV, Fixed, 95% CI)

‐13.80 [‐56.02, 28.42]

7 Fear of falling Show forest plot

1

47

Odds Ratio (M‐H, Fixed, 95% CI)

3.40 [0.63, 18.22]

8 Range of movement Show forest plot

1

376

Mean Difference (IV, Fixed, 95% CI)

4.26 [1.96, 6.55]

8.1 Active cervical rotation, left

1

47

Mean Difference (IV, Fixed, 95% CI)

3.97 [‐4.70, 12.64]

8.2 Active cervical rotation, right

1

47

Mean Difference (IV, Fixed, 95% CI)

7.40 [‐0.42, 15.22]

8.3 Active cervical lateral flexion, left

1

47

Mean Difference (IV, Fixed, 95% CI)

1.5 [‐2.61, 5.61]

8.4 Active cervical lateral flexion, right

1

47

Mean Difference (IV, Fixed, 95% CI)

6.64 [1.95, 11.33]

8.5 Hamstrings passive ROM, left

1

47

Mean Difference (IV, Fixed, 95% CI)

7.80 [1.33, 14.27]

8.6 Hamstrings passive ROM, right

1

47

Mean Difference (IV, Fixed, 95% CI)

‐0.43 [‐6.25, 5.39]

8.7 Hip flexion active ROM, left

1

47

Mean Difference (IV, Fixed, 95% CI)

30.11 [‐2.25, 62.47]

8.8 Hip flexion active ROM, right

1

47

Mean Difference (IV, Fixed, 95% CI)

32.45 [4.69, 60.21]

9 Strength Show forest plot

1

94

Mean Difference (IV, Fixed, 95% CI)

‐1.32 [‐2.75, 0.12]

9.1 Upper extremity strength

1

47

Mean Difference (IV, Fixed, 95% CI)

‐1.67 [‐4.76, 1.42]

9.2 Lower extremity strength

1

47

Mean Difference (IV, Fixed, 95% CI)

‐1.22 [‐2.84, 0.40]

10 Endurance Show forest plot

1

94

Mean Difference (IV, Fixed, 95% CI)

‐7.89 [‐20.18, 4.41]

10.1 6‐minute walk

1

47

Mean Difference (IV, Fixed, 95% CI)

‐31.80 [‐263.55, 199.95]

10.2 2‐minute step test

1

47

Mean Difference (IV, Fixed, 95% CI)

‐7.82 [‐20.13, 4.49]

11 Pain Show forest plot

1

47

Mean Difference (IV, Fixed, 95% CI)

‐1.31 [‐8.29, 5.67]

12 Disability Show forest plot

1

47

Odds Ratio (M‐H, Fixed, 95% CI)

2.08 [0.50, 8.60]

13 Depression: Geriatric Depression Scale (GDS15) Show forest plot

1

22

Mean Difference (IV, Fixed, 95% CI)

‐2.10 [‐4.70, 0.50]

14 State Trait Anxiety (STAI‐Y1) Show forest plot

1

22

Mean Difference (IV, Fixed, 95% CI)

‐8.40 [‐16.74, ‐0.06]

15 Trait Anxiety Inventory (STAI‐Y2) Show forest plot

1

22

Mean Difference (IV, Fixed, 95% CI)

‐6.70 [‐15.35, 1.95]

Figuras y tablas -
Comparison 1. Yoga and waitlist control