Topical azelaic acid, salicylic acid, nicotinamide, and sulphur for acne
Información
- DOI:
- https://doi.org/10.1002/14651858.CD011368Copiar DOI
- Base de datos:
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- Cochrane Database of Systematic Reviews
- Versión publicada:
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- 12 noviembre 2014see what's new
- Tipo:
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- Intervention
- Etapa:
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- Protocol
- Grupo Editorial Cochrane:
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Grupo Cochrane de Piel
- Copyright:
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- Copyright © 2014 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Cifras del artículo
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Autores
Contributions of authors
HS was the contact person with the editorial base.
HL and HS co‐ordinated the contributions from the co‐authors and wrote the final draft of the protocol.
HL, HS, and JX worked on the methods sections.
HY drafted the clinical sections of the background and responded to the clinical comments of the referees.
HL and GL responded to the methodology and statistics comments of the referees.
HY, HL, HS, and JX contributed to writing the protocol.
LL was the consumer co‐author and checked the protocol for readability and clarity. She also ensured that the outcomes are relevant to consumers.
HS is the guarantor of the final review.
Disclaimer
The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the NIHR, NHS, or the Department of Health, UK.
Sources of support
Internal sources
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Jinling Hospital, Nanjing, China.
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Zhejiang University, Hangzhou, China.
External sources
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The National Institute for Health Research (NIHR), UK.
The NIHR, UK, is the largest single funder of the Cochrane Skin Group.
Declarations of interest
Haibo Liu: Nothing to declare.
Haiyan Yu: Nothing to declare.
Jun Xia: Nothing to declare.
Ling Liu: Nothing to declare.
Guan J Liu: Nothing to declare.
Hong Sang: Nothing to declare.
Acknowledgements
The authors would like to thank the Cochrane Skin Group editorial base for their support in the completion of this protocol.
The authors would also like to thank Dr Chunbo Li (Department of Biological Psychiatry, Shanghai Mental Health Centre, Shanghai Jiao Tong University School of Medicine, Shanghai, China) for the comments in the preparation of the protocol.
The authors would also like to thank Hannah Jones (Division of Psychiatry and Applied Psychology, School of Medicine, Institute of Mental Health, University of Nottingham Innovation Park, Nottingham) for the English language revision.
The Cochrane Skin Group editorial base wishes to thank Robert Dellavalle, who was the Cochrane Dermatology Editor for this protocol; Matthew Grainge and Thomas Chu, who were the Statistical Editors; Ching‐Chi Chi, who was Methods Editor; the clinical referee, Jerry Tan; and the consumer referees, Lyn Charland and Jodi Duke.
Version history
| Published | Title | Stage | Authors | Version |
| 2020 May 01 | Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne | Review | Haibo Liu, Haiyan Yu, Jun Xia, Ling Liu, Guan J Liu, Hong Sang, Frank Peinemann | |
| 2014 Nov 12 | Topical azelaic acid, salicylic acid, nicotinamide, and sulphur for acne | Protocol | Haibo Liu, Haiyan Yu, Jun Xia, Ling Liu, Guan J Liu, Hong Sang | |
Keywords
MeSH
Medical Subject Headings (MeSH) Keywords
- Acne Vulgaris [*drug therapy];
- Adapalene [adverse effects, therapeutic use];
- Anti-Bacterial Agents [therapeutic use];
- Benzoyl Peroxide [therapeutic use];
- Bias;
- Clindamycin [adverse effects, therapeutic use];
- Dermatologic Agents [adverse effects, *therapeutic use];
- Dicarboxylic Acids [adverse effects, therapeutic use];
- Erythromycin [adverse effects, therapeutic use];
- Glycolates [therapeutic use];
- Keratolytic Agents [therapeutic use];
- Mandelic Acids [therapeutic use];
- Niacinamide [adverse effects, therapeutic use];
- Patient Dropouts [statistics & numerical data];
- Pyruvic Acid [adverse effects, therapeutic use];
- Quality of Life;
- Salicylic Acid [therapeutic use];
- Sulfur [therapeutic use];
- Tretinoin [therapeutic use];
- Zinc [therapeutic use];
Medical Subject Headings Check Words
Adolescent; Adult; Child; Female; Humans; Male; Young Adult;
PICO
| Medical term | Explanation |
| Acne conglobata | A severe form of acne presenting with numerous comedones and large abscessesa |
| Acne fulminans | A severe form of cystic acne presenting with highly inflammatory nodules and plaquesa |
| Acne mechanica | A form of acne caused by the pressure of tight clothing or frictionb |
| Acne vulgaris | A common chronic skin disorder of sebaceous follicles, mainly affecting the face, chest, and backa |
| Chemokine | A group of small cytokines that act as chemical messengers to induce chemotaxis in leukocytesc |
| Comedone | A clogged hair follicle in the skin. It can present as a blackhead or whiteheada |
| Cytokine | A small protein released by cells that function as molecular messengers between cellsc |
| Erythema | Redness of the skin, caused by vascular congestion or increased perfusionb |
| Excoriated acne | Compulsive squeezing and scratching of acne lesions with resultant scabs and scarsa |
| Halogen acne | A form of acne caused by iodides, bromides, and halogensb |
| Hyperkeratosis | Thickening of the outer layer of skin often associated with a quantitative abnormality of keratinb |
| Keratinocytes | The predominant cell type in the epidermis, forming a touch protective layera |
| Microcomedones | Early and small plugging of the follicle with excess keratin and sebumb |
| Nodule | A solid mass in the skin, more than 0.5 cm in diameterb |
| Papule | A circumscribed palpable elevation, less than 0.5 cm in diameterb |
| Pilosebaceous unit | A structure consisting of a hair follicle, sebaceous gland, and an arrector pili muscleb |
| Propionibacterium acnes | Gram‐positive bacterium related to acne developmentb |
| Pustule | A visible accumulation of free pusb |
| Scar | Skin areas of fibrous tissue replacing normal skin after injuryb |
| Sebum | The oily, waxy substance produced by sebaceous glandsb |
| Stratum corneum | The outermost layer of the epidermis, where cells have lost nuclei and cytoplasmic organellesb |
| Toll‐like receptor | A class of proteins that recognise conserved products unique to microbial metabolism in immune responsec |
| aAndrews' Diseases of the Skin: Clinical Dermatology, 11th Edition, 2011, Elsevier Inc. bRook's Textbook of Dermatology, Eighth Edition, 2010, Blackwell Publishing Ltd. cImmunology, Sixth Edition, 2001, Harcourt Asia Pte Ltd. | |
| Acne vulgaris | |
| Acne variants: | Neonatal acne |
| Infantile acne | |
| Acne conglobata | |
| Acne fulminans | |
| SAPHO syndrome | |
| PAPA syndrome | |
| Acne excoriee des jeunes filles | |
| Acne mechanica | |
| Acne with solid facial oedema | |
| Acne with associated endocrinology abnormalities | |
| Acneiform eruptions: | Steroid folliculitis |
| Drug‐induced acne | |
| Epidermal growth factor receptor inhibitor associated eruption | |
| Occupational acne and chloracne | |
| Gram‐negative folliculitis | |
| Radiation acne | |
| Tropical acne | |
| Acne aestivalis | |
| Pseudoacne of the nasal crease | |
| Apert syndrome | |
| aFitzpatrick's Dermatology in General Medicine, Eighth edition, 2012, The McGraw‐Hill Companies, Inc. | |
