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Cochrane Database of Systematic Reviews

توقف مصرف بتا2‐آگونیست طولانی‌اثر (LABA) در کودکان مبتلا به آسم که به خوبی با LABA و کورتیکواستروئیدهای استنشاقی کنترل می‌شوند

Información

DOI:
https://doi.org/10.1002/14651858.CD011316.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 21 mayo 2015see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Vías respiratorias

Copyright:
  1. Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Contraer

Autores

  • Kayleigh M Kew

    Correspondencia a: British Medical Journal Technology Assessment Group (BMJ‐TAG), BMJ Knowledge Centre, London, UK

    [email protected]

  • Sean Beggs

    Department of Paediatrics, Royal Hobart Hospital, Hobart, Australia

    School of Medicine, University of Tasmania, Hobart, Australia

  • Shaleen Ahmad

    Population Health Research Institute, St George's, University of London, London, UK

Contributions of authors

Shaleen Ahmad searched clinicaltrials.gov and drug company trial registries. Shaleen Ahmad and Kayleigh Kew sifted the main electronic search and the results from additional searching, and compiled the study shortlist. Sean Beggs and Kayleigh Kew made the final decisions on study exclusion. Kayleigh Kew wrote up the draft manuscript with clinical and editorial appraisal from Sean Beggs.

Sources of support

Internal sources

  • Kayleigh Kew, UK.

    St George's University, London

  • Shaleen Ahmad, UK.

    St George's University, London

  • Sean Beggs, Other.

    No such funding was received for this review

External sources

  • Kayleigh Kew, UK.

    National Institute of Health Research: Evidence to guide care in adults and children with asthma, 13/89/14

Declarations of interest

Kayleigh Kew: none known

Sean Beggs: none known

Shaleen Ahmad: none known

Acknowledgements

We would like to thank Rebecca Normansell, who contributed to the related protocol and review addressing this question in adults (Ahmad 2014), which informed the design of this review. We also thank Elizabeth Stovold for designing the search strategy and running the main electronic searches.

Jimmy Chong was the Editor for this review and commented critically on the review.

The Background and Methods sections of this review are based on a standard template used by the Cochrane Airways Group.

Cochrane Review Group funding acknowledgement: The National Institute for Health Research (NIHR) is the largest single funder of the Cochrane Airways Group.

Disclaimer: The views and opinions expressed herein are those of the review authors and do not necessarily reflect those of the NIHR, the National Health Service or the Department of Health.

Version history

Published

Title

Stage

Authors

Version

2015 May 21

Stopping long‐acting beta2‐agonists (LABA) for children with asthma well controlled on LABA and inhaled corticosteroids

Review

Kayleigh M Kew, Sean Beggs, Shaleen Ahmad

https://doi.org/10.1002/14651858.CD011316.pub2

2014 Sep 22

Stopping long‐acting beta2‐agonists (LABA) for children with asthma well controlled on LABA and inhaled corticosteroids

Protocol

Kayleigh M Kew, Sean Beggs

https://doi.org/10.1002/14651858.CD011316

Differences between protocol and review

No trials met the inclusion criteria for this review, we were unable to conduct meta‐analyses, implement any of the data analysis plan, or conduct any of the planned subgroup or sensitivity analyses.

Keywords

MeSH

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.

Results of the search and study selection process
Figuras y tablas -
Figure 1

Results of the search and study selection process

Stopping long‐acting beta2‐agonists (LABA) compared with continuing inhaled corticosteroids (ICS) + LABA for children with well‐controlled asthma

Patient or population: children (aged 18 years or younger) whose asthma is well controlled on combination ICS + LABA

Settings: outpatient

Intervention: stopping LABA

Comparison: continuing ICS + LABA

Outcomes

No of Participants
(studies)

Comments

Exacerbations requiring systemic corticosteroids

0 (0)

No studies met the inclusion criteria for the review

Asthma control (validated scales)

0 (0)

Serious adverse events (all cause)

0 (0)

Quality of life (validated scales)

0 (0)

Exacerbations requiring hospitalisation or emergency department visit

0 (0)

Adverse events (all cause)

0 (0)

Withdrawals

0 (0)

Figuras y tablas -