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Cochrane Database of Systematic Reviews

Profilaxis primaria para la tromboembolia venosa en pacientes sometidos a amputación principal del miembro inferior

Esta versión no es la más reciente

Información

DOI:
https://doi.org/10.1002/14651858.CD010525.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 16 diciembre 2013see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Vascular

Copyright:
  1. Copyright © 2013 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Autores

  • Lindsay Robertson

    Correspondencia a: Department of Vascular Surgery, The Freeman Hospital, Newcastle upon Tyne, UK

    [email protected]

    [email protected]

  • Aidan Roche

    University of Newcastle, Newcastle Upon Tyne, UK

Contributions of authors

LR: drafted the protocol, selected studies for inclusion, assessed the quality of studies, performed data analysis and wrote the review.
AR: contributed to the protocol, selected studies for inclusion, assessed the quality of studies and contributed to the text of the review.

Sources of support

Internal sources

  • No sources of support supplied

External sources

  • National Institute for Health Research (NIHR), UK.

    The authors are supported by a programme grant from the NIHR.

  • Chief Scientist Office, Scottish Government Health Directorates, The Scottish Government, UK.

    The PVD Group editorial base is supported by the Chief Scientist Office.

  • National Institute for Health Research (NIHR), UK.

    The PVD Group editorial base is supported by a programme grant from the NIHR.

Declarations of interest

None known

Acknowledgements

Thanks to Karen Welch (TSC), Cochrane Peripheral Vascular Disease Group, for conducting the search for the studies and to all the other members of the group for their assistance in this review.

Version history

Published

Title

Stage

Authors

Version

2020 Jul 21

Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity

Review

David RB Herlihy, Matthew Thomas, Quoc H Tran, Vikram Puttaswamy

https://doi.org/10.1002/14651858.CD010525.pub3

2013 Dec 16

Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity

Review

Lindsay Robertson, Aidan Roche

https://doi.org/10.1002/14651858.CD010525.pub2

2013 May 31

Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity

Protocol

Lindsay Robertson, Aidan Roche

https://doi.org/10.1002/14651858.CD010525

Keywords

MeSH

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.

Study flow diagram.
Figuras y tablas -
Figure 1

Study flow diagram.

Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
Figuras y tablas -
Figure 2

Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.

Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
Figuras y tablas -
Figure 3

Risk of bias summary: review authors' judgements about each risk of bias item for each included study.

Comparison 1 Unfractionated heparin versus low molecular weight heparin, Outcome 1 Deep vein thrombosis (DVT).
Figuras y tablas -
Analysis 1.1

Comparison 1 Unfractionated heparin versus low molecular weight heparin, Outcome 1 Deep vein thrombosis (DVT).

Comparison 2 Heparin versus placebo, Outcome 1 Pulmonary embolism.
Figuras y tablas -
Analysis 2.1

Comparison 2 Heparin versus placebo, Outcome 1 Pulmonary embolism.

Comparison 1. Unfractionated heparin versus low molecular weight heparin

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Deep vein thrombosis (DVT) Show forest plot

1

Odds Ratio (M‐H, Fixed, 95% CI)

Totals not selected

Figuras y tablas -
Comparison 1. Unfractionated heparin versus low molecular weight heparin
Comparison 2. Heparin versus placebo

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Pulmonary embolism Show forest plot

1

Odds Ratio (M‐H, Fixed, 95% CI)

Totals not selected

1.1 Above knee amputation

1

Odds Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

1.2 Below knee amputation

1

Odds Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

Figuras y tablas -
Comparison 2. Heparin versus placebo