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Cochrane Database of Systematic Reviews

Mayor consumo de fruta y vegetales para la prevención primaria de las enfermedades cardiovasculares

Información

DOI:
https://doi.org/10.1002/14651858.CD009874.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 04 junio 2013see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:

  1. Grupo Cochrane de Corazón

Copyright:
  1. Copyright © 2013 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Autores

  • Louise Hartley

    RTI Health Solutions, Manchester, UK

  • Ewemade Igbinedion

    Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK

  • Jennifer Holmes

    Warwick Medical School, University of Warwick, Coventry, UK

  • Nadine Flowers

    Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK

  • Margaret Thorogood

    Public Health and Epidemiology, Division of Health Sciences, Coventry, UK

  • Aileen Clarke

    Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK

  • Saverio Stranges

    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, Canada

  • Lee Hooper

    Norwich Medical School, University of East Anglia, Norwich, UK

  • Karen Rees

    Correspondencia a: Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK

    [email protected]

    [email protected]

Contributions of authors

All review authors contributed to the protocol development. The Trials Search Co‐ordinators of the CHG ran the searches, LH and EI screened titles and abstracts and assessed studies for formal inclusion or exclusion. LH and JH abstracted data and assessed methodological quality. LH and KR conducted the analysis, and wrote the first draft of the review. All authors contributed to later drafts.

Sources of support

Internal sources

  • Warwick Medical School, University of Warwick, UK

  • Norwich Medical School, University of East Anglia, UK

External sources

  • NIHR Cochrane Programme Grant, UK

Declarations of interest

None known.

Acknowledgements

We are grateful to Nicole Martin and Jo Abbot for conducting the searches for this review. We would also like to acknowledge Dr Dichi for providing additional data from his trial (Dichi 2011).

Version history

Published

Title

Stage

Authors

Version

2013 Jun 04

Increased consumption of fruit and vegetables for the primary prevention of cardiovascular diseases

Review

Louise Hartley, Ewemade Igbinedion, Jennifer Holmes, Nadine Flowers, Margaret Thorogood, Aileen Clarke, Saverio Stranges, Lee Hooper, Karen Rees

https://doi.org/10.1002/14651858.CD009874.pub2

2012 May 16

Increased consumption of fruit and vegetables for the primary prevention of cardiovascular diseases

Protocol

Louise Hartley, Ewemade Igbinedion, Margaret Thorogood, Aileen Clarke, Saverio Stranges, Lee Hooper, Karen Rees

https://doi.org/10.1002/14651858.CD009874

Differences between protocol and review

It was our intention to perform stratified analyses to examine the effects of intensity and duration of interventions, and different components of the intervention, but there were insufficient trials included in the review to do this. Similarly, we intended to perform sensitivity analyses to examine the effects of low methodological quality and perform funnel plots to assess publication bias. We also intended to focus on studies with follow‐up of six months or more but again studies with this length of follow‐up were lacking and so studies with follow‐up of three months or more were included. These will be addressed in future updates of this review when more evidence accrues.

Notes

Keywords

MeSH

Medical Subject Headings (MeSH) Keywords

Medical Subject Headings Check Words

Adult; Humans;

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.

Study flow diagram.

Figuras y tablas -
Figure 1

Study flow diagram.

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'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.

Figuras y tablas -
Figure 2

'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.

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'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.

Figuras y tablas -
Figure 3

'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.

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Comparison 1: Advice to eat fruit and vegetables, Outcome 1: Systolic blood pressure, change from baseline (mmHg)

Figuras y tablas -
Analysis 1.1

Comparison 1: Advice to eat fruit and vegetables, Outcome 1: Systolic blood pressure, change from baseline (mmHg)

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Comparison 1: Advice to eat fruit and vegetables, Outcome 2: Diastolic blood pressure, change from baseline (mmHg)

Figuras y tablas -
Analysis 1.2

Comparison 1: Advice to eat fruit and vegetables, Outcome 2: Diastolic blood pressure, change from baseline (mmHg)

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Comparison 1: Advice to eat fruit and vegetables, Outcome 3: Total cholesterol, change from baseline (mmol/l)

Figuras y tablas -
Analysis 1.3

Comparison 1: Advice to eat fruit and vegetables, Outcome 3: Total cholesterol, change from baseline (mmol/l)

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Comparison 1: Advice to eat fruit and vegetables, Outcome 4: LDL cholesterol, change from baseline (mmol/l)

Figuras y tablas -
Analysis 1.4

Comparison 1: Advice to eat fruit and vegetables, Outcome 4: LDL cholesterol, change from baseline (mmol/l)

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Comparison 1: Advice to eat fruit and vegetables, Outcome 5: HDL cholesterol, change from baseline (mmol/l)

Figuras y tablas -
Analysis 1.5

Comparison 1: Advice to eat fruit and vegetables, Outcome 5: HDL cholesterol, change from baseline (mmol/l)

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Comparison 1: Advice to eat fruit and vegetables, Outcome 6: Triglycerides, change from baseline (mmol/l)

Figuras y tablas -
Analysis 1.6

Comparison 1: Advice to eat fruit and vegetables, Outcome 6: Triglycerides, change from baseline (mmol/l)

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Comparison 2: Provision of fruit and vegetables, Outcome 1: Systolic blood pressure, change from baseline (mmHg)

Figuras y tablas -
Analysis 2.1

Comparison 2: Provision of fruit and vegetables, Outcome 1: Systolic blood pressure, change from baseline (mmHg)

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Comparison 2: Provision of fruit and vegetables, Outcome 2: Diastolic blood pressure, change from baseline (mmHg)

Figuras y tablas -
Analysis 2.2

Comparison 2: Provision of fruit and vegetables, Outcome 2: Diastolic blood pressure, change from baseline (mmHg)

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Comparison 2: Provision of fruit and vegetables, Outcome 3: Total cholesterol, change from baseline (mmol/l)

Figuras y tablas -
Analysis 2.3

Comparison 2: Provision of fruit and vegetables, Outcome 3: Total cholesterol, change from baseline (mmol/l)

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Comparison 2: Provision of fruit and vegetables, Outcome 4: LDL cholesterol, change from baseline (mmol/l)

Figuras y tablas -
Analysis 2.4

Comparison 2: Provision of fruit and vegetables, Outcome 4: LDL cholesterol, change from baseline (mmol/l)

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Comparison 2: Provision of fruit and vegetables, Outcome 5: HDL cholesterol, change from baseline (mmol/l)

Figuras y tablas -
Analysis 2.5

Comparison 2: Provision of fruit and vegetables, Outcome 5: HDL cholesterol, change from baseline (mmol/l)

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Comparison 2: Provision of fruit and vegetables, Outcome 6: Trigylcerides, change from baseline (mmol/l)

Figuras y tablas -
Analysis 2.6

Comparison 2: Provision of fruit and vegetables, Outcome 6: Trigylcerides, change from baseline (mmol/l)

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Comparison 1. Advice to eat fruit and vegetables

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1.1 Systolic blood pressure, change from baseline (mmHg) Show forest plot

2

891

Mean Difference (IV, Fixed, 95% CI)

‐3.00 [‐4.92, ‐1.09]

1.2 Diastolic blood pressure, change from baseline (mmHg) Show forest plot

2

891

Mean Difference (IV, Fixed, 95% CI)

‐0.90 [‐2.03, 0.24]

1.3 Total cholesterol, change from baseline (mmol/l) Show forest plot

4

970

Mean Difference (IV, Fixed, 95% CI)

‐0.01 [‐0.11, 0.09]

1.4 LDL cholesterol, change from baseline (mmol/l) Show forest plot

2

251

Mean Difference (IV, Fixed, 95% CI)

‐0.17 [‐0.38, 0.03]

1.5 HDL cholesterol, change from baseline (mmol/l) Show forest plot

2

251

Mean Difference (IV, Fixed, 95% CI)

‐0.01 [‐0.10, 0.08]

1.6 Triglycerides, change from baseline (mmol/l) Show forest plot

3

280

Mean Difference (IV, Fixed, 95% CI)

0.10 [‐0.06, 0.27]
Figuras y tablas -
Comparison 1. Advice to eat fruit and vegetables
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Comparison 2. Provision of fruit and vegetables

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

2.1 Systolic blood pressure, change from baseline (mmHg) Show forest plot

1

157

Mean Difference (IV, Fixed, 95% CI)

1.00 [0.45, 1.55]

2.2 Diastolic blood pressure, change from baseline (mmHg) Show forest plot

1

157

Mean Difference (IV, Fixed, 95% CI)

1.50 [1.18, 1.82]

2.3 Total cholesterol, change from baseline (mmol/l) Show forest plot

2

187

Mean Difference (IV, Random, 95% CI)

‐0.10 [‐0.24, 0.04]

2.4 LDL cholesterol, change from baseline (mmol/l) Show forest plot

3

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

2.5 HDL cholesterol, change from baseline (mmol/l) Show forest plot

3

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

2.6 Trigylcerides, change from baseline (mmol/l) Show forest plot

3

284

Mean Difference (IV, Fixed, 95% CI)

‐0.01 [‐0.03, 0.01]
Figuras y tablas -
Comparison 2. Provision of fruit and vegetables
Ir a la tabla de la revisión