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Study flow diagram.
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Figure 1

Study flow diagram.

Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
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Figure 2

Risk of bias summary: review authors' judgements about each risk of bias item for each included study.

Forest plot of comparison: 1 Early school start vs late school start, outcome: 1.1 School‐night sleep duration.
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Figure 3

Forest plot of comparison: 1 Early school start vs late school start, outcome: 1.1 School‐night sleep duration.

Forest plot of comparison: 1 Early school start vs Late school start, outcome: 1.2 BMI Score ‐ Cross‐over trial.
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Figure 4

Forest plot of comparison: 1 Early school start vs Late school start, outcome: 1.2 BMI Score ‐ Cross‐over trial.

Forest plot of comparison: 1 Early school start vs Late school start, outcome: 1.3 Waist Circumference ‐ Cross‐over trial.
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Figure 5

Forest plot of comparison: 1 Early school start vs Late school start, outcome: 1.3 Waist Circumference ‐ Cross‐over trial.

Forest plot of comparison: 1 Early school start vs Late school start, outcome: 1.4 Body Fat ‐ Cross‐over trial.
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Figure 6

Forest plot of comparison: 1 Early school start vs Late school start, outcome: 1.4 Body Fat ‐ Cross‐over trial.

Comparison 1 Early school start vs late school start, Outcome 1 School‐night sleep duration.
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Analysis 1.1

Comparison 1 Early school start vs late school start, Outcome 1 School‐night sleep duration.

Comparison 1 Early school start vs late school start, Outcome 2 BMI score ‐ QED.
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Analysis 1.2

Comparison 1 Early school start vs late school start, Outcome 2 BMI score ‐ QED.

Comparison 1 Early school start vs late school start, Outcome 3 Waist circumference ‐ QED.
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Analysis 1.3

Comparison 1 Early school start vs late school start, Outcome 3 Waist circumference ‐ QED.

Comparison 1 Early school start vs late school start, Outcome 4 Body fat ‐ QED.
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Analysis 1.4

Comparison 1 Early school start vs late school start, Outcome 4 Body fat ‐ QED.

Comparison 1 Early school start vs late school start, Outcome 5 School‐night sleep duration ‐ RCT.
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Analysis 1.5

Comparison 1 Early school start vs late school start, Outcome 5 School‐night sleep duration ‐ RCT.

Comparison 1 Early school start vs late school start, Outcome 6 Concentration performance ‐ RCT.
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Analysis 1.6

Comparison 1 Early school start vs late school start, Outcome 6 Concentration performance ‐ RCT.

Comparison 1 Early school start vs late school start, Outcome 7 Attention level ‐ RCT.
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Analysis 1.7

Comparison 1 Early school start vs late school start, Outcome 7 Attention level ‐ RCT.

Comparison 1 Early school start vs late school start, Outcome 8 Peer support ‐ QED.
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Analysis 1.8

Comparison 1 Early school start vs late school start, Outcome 8 Peer support ‐ QED.

Comparison 1 Early school start vs late school start, Outcome 9 Social support ‐ QED.
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Analysis 1.9

Comparison 1 Early school start vs late school start, Outcome 9 Social support ‐ QED.

Comparison 1 Early school start vs late school start, Outcome 10 Extracurricular activities ‐ QED.
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Analysis 1.10

Comparison 1 Early school start vs late school start, Outcome 10 Extracurricular activities ‐ QED.

Comparison 1 Early school start vs late school start, Outcome 11 Academics ‐ QED.
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Analysis 1.11

Comparison 1 Early school start vs late school start, Outcome 11 Academics ‐ QED.

Comparison 1 Early school start vs late school start, Outcome 12 Risk of losing sleep ‐ QED.
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Analysis 1.12

Comparison 1 Early school start vs late school start, Outcome 12 Risk of losing sleep ‐ QED.

Comparison 1 Early school start vs late school start, Outcome 13 Overly sleepy ‐ QED.
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Analysis 1.13

Comparison 1 Early school start vs late school start, Outcome 13 Overly sleepy ‐ QED.

Comparison 1 Early school start vs late school start, Outcome 14 Sleepiness ‐ QED.
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Analysis 1.14

Comparison 1 Early school start vs late school start, Outcome 14 Sleepiness ‐ QED.

Comparison 1 Early school start vs late school start, Outcome 15 Percentage of students getting adequate sleep.
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Analysis 1.15

Comparison 1 Early school start vs late school start, Outcome 15 Percentage of students getting adequate sleep.

Summary of findings for the main comparison. Early versus delayed school starts

Early versus delayed school starts

Patient or population: students aged 13‐19
Setting: Canada (Toronto), USA (Colorado, Rhode Island, Minnesota, Kentucky, North Carolina, Wyoming), northern Israel, New Zealand (Wellington), Croatia, and southern Brazil
Intervention: later school start times (08:00, 08:45, 09:00, 10:00, or 10:30; start time delayed by 60‐90 minutes)
Comparison: early school start time (07:00, 07:15, 07:20, or 07:30)

Outcomes

Impacts

№ of Participants (studies)

Quality of the evidence
(GRADE)

Student academic outcomes

There is no clear association between later school start times and student academic outcomes, as two studies reported significant positive associations (b = 1.78, b = 0.98; effect sizes could not be calculated from one study), one study reported a non‐significant negative association (b = −0.02), and one study reported a significant negative association (MD −0.32 GPA points on a scale of 0 to 4, with higher GPAs indicating better grades).

254,743

(4)

⊕⊝⊝⊝
Very lowa

Amount or quality of sleep

All studies that evaluated the association between later school start times and amount or quality of sleep reported significant positive associations, providing evidence that later school start times are associated with increased sleep (effect sizes ranged from MD 0.49 to 1.95 hours) and lower risk of losing sleep (RR 0.41).

52,340

(8)

⊕⊝⊝⊝
Very lowa

Mental health outcomes

There is limited evidence concerning the association between later school start times and mental health outcomes: one study reported significant differences in self‐reported depression symptoms for students in later starting schools (07:25 and 08:30) than earlier starting schools (07:15), but no significant difference between students starting school at 08:30 vs 07:25.

1200

(1)

⊕⊝⊝⊝
Very lowa

Truancy or attendance outcomes

There is mixed evidence concerning the association between later school starts and attendance outcomes: one study reported a significant increase in attendance, one study reported a non‐significant increase in attendance, and one study reported a significant increase in attendance for 2 of 6 schools and non‐significant effects (no further information provided) for the other 4 schools.

255,122

(4)

⊕⊝⊝⊝
Very lowa

Alertness

There is mixed evidence concerning the association between later school starts and student reports of alertness or sleepiness. Two studies found an association between later school start times and decreased daytime sleepiness, while one study found no difference between student reports at later and earlier starting schools. One study reported a significant increase in attention levels but a non‐significant increase in concentration levels.

2735

(4)

⊕⊝⊝⊝
Very lowa

Adverse events/unintended consequences

Authors provided limited information concerning adverse events and unintended consequences but did offer that later school start times may be associated with decreased morning interactions between parents and children, decreased alertness in mid‐afternoon, and increased logistical challenges, including missing extracurricular activities, transportation troubles, and safety concerns (as students may have to walk home in the dark).

207,576

(4)

⊕⊝⊝⊝
Very lowa

b: regression coefficient; CI: confidence interval; GPA: grade point average; MD: mean difference; RR: risk ratio

GRADE Working Group grades of evidence
High quality: we are very confident that the true effect lies close to that of the estimate of the effect.
Moderate quality: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
Low quality: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect.
Very low quality: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect.

aDowngraded one level (from starting point of 'low' for observational study designs). The GRADE rating of 'very low' for all findings reflects study designs (absence of RCTs), high risk of bias within the studies, and inconsistency within the estimates.

Figuras y tablas -
Summary of findings for the main comparison. Early versus delayed school starts
Comparison 1. Early school start vs late school start

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 School‐night sleep duration Show forest plot

2

1022

Mean Difference (IV, Random, 95% CI)

1.39 [0.38, 2.39]

2 BMI score ‐ QED Show forest plot

1

379

Mean Difference (IV, Random, 95% CI)

‐0.08 [‐0.30, 0.13]

3 Waist circumference ‐ QED Show forest plot

1

379

Mean Difference (IV, Random, 95% CI)

‐1.14 [‐3.34, 1.06]

4 Body fat ‐ QED Show forest plot

1

379

Mean Difference (IV, Random, 95% CI)

‐1.45 [‐2.63, ‐0.27]

5 School‐night sleep duration ‐ RCT Show forest plot

1

Mean Difference (IV, Random, 95% CI)

Totals not selected

6 Concentration performance ‐ RCT Show forest plot

1

Mean Difference (IV, Random, 95% CI)

Totals not selected

7 Attention level ‐ RCT Show forest plot

1

Mean Difference (IV, Random, 95% CI)

Totals not selected

8 Peer support ‐ QED Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

9 Social support ‐ QED Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

10 Extracurricular activities ‐ QED Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

11 Academics ‐ QED Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

12 Risk of losing sleep ‐ QED Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

13 Overly sleepy ‐ QED Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

14 Sleepiness ‐ QED Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

15 Percentage of students getting adequate sleep Show forest plot

1

905

Risk Ratio (M‐H, Random, 95% CI)

1.50 [1.33, 1.70]

Figuras y tablas -
Comparison 1. Early school start vs late school start