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Cochrane Database of Systematic Reviews

Interventions for the management of dry mouth: topical therapies

Información

DOI:
https://doi.org/10.1002/14651858.CD008934.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 07 diciembre 2011see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Salud oral

Copyright:
  1. Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Autores

  • Susan Furness

    Correspondencia a: Cochrane Oral Health Group, School of Dentistry, The University of Manchester, Manchester, UK

    [email protected]

    [email protected]

  • Helen V Worthington

    Cochrane Oral Health Group, School of Dentistry, The University of Manchester, Manchester, UK

  • Gemma Bryan

    Cochrane Oral Health Group, School of Dentistry, The University of Manchester, Manchester, UK

  • Sarah Birchenough

    Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK

  • Roddy McMillan

    Eastman Dental Hospital, London, UK

Contributions of authors

Susan Furness (SF) registered the title and produced the first draft of the background, objectives and methods sections.

Helen Worthington (HW) wrote the data collection and analysis sections and commented on the draft protocol.

Gemma Bryan (GB), Sarah Birchenough (SB) and Roddy McMillan (RM) commented on the draft protocol and search strategy.

SF and GB scanned the search results, identified included and excluded studies. SF, GB and RM undertook risk of bias assessment and SF, GB, RM and HW undertook data extraction.

GB wrote the description of studies section.

SF drafted the effects of interventions, discussion and conclusion sections.

SB and RM commented on the draft review and added clinical comments.

Sources of support

Internal sources

  • The University of Manchester, UK.

  • MAHSC, UK.

    The Cochrane Oral Health Group is supported by the Manchester Academic Health Sciences Centre (MAHSC) and the NIHR Manchester Biomedical Research Centre

External sources

  • Department of Health, Cochrane Incentive Scheme 2010, UK.

    Provided GBP 5000 to support this review

  • British Orthodontic Society (BOS), UK.

    The BOS have provided funding for the Cochrane Oral Health Group Global Alliance (see www.ohg.cochrane.org)

Declarations of interest

None known.

Acknowledgements

We acknowledge the assistance of Anne Littlewood, Trials Search Co‐ordinator of the Cochrane Oral Health Group, for designing the search strategy and undertaking the electronic searches. Our thanks also to Philip Riley, Deputy Managing Editor, for his assistance in determining possible overlaps between this review and other reviews registered with other Cochrane Review Groups, and also for obtaining paper copies of studies for appraisal by the review team.

Thanks to our translators: Toru Naito (Japanese), Shi Zongdao and Chunjie Li (Chinese).

Version history

Published

Title

Stage

Authors

Version

2011 Dec 07

Interventions for the management of dry mouth: topical therapies

Review

Susan Furness, Helen V Worthington, Gemma Bryan, Sarah Birchenough, Roddy McMillan

https://doi.org/10.1002/14651858.CD008934.pub2

2011 Jan 19

Interventions for the management of dry mouth: non‐systemic therapies

Protocol

Susan Furness, Helen V Worthington, Gemma Bryan, Sarah Birchenough, Roddy McMillan

https://doi.org/10.1002/14651858.CD008934

Differences between protocol and review

In the protocol we planned to evaluate non‐systemic therapies for dry mouth. However, during the data extraction phase it became obvious that when products are applied to the oral mucosa there will always be some systemic absorption. Most trials do not measure this therefore it was decided to change the title of this review to 'Topical interventions for the management of dry mouth'. Inclusion criteria were changed to include both saliva substitutes and salivary stimulants administered in the form of sprays, gels, pastes, mouthwashes, gums or lozenges, regardless of whether these products were subsequently swallowed. Trials evaluating acupuncture or electrostimulation as a treatment for dry mouth will be included in a separate review.