Lamotrigine adjunctive therapy for refractory generalized tonic‐clonic seizures

Scolaris Content Display Scolaris Content Display

Ir a:

Analysis 1.1

Comparison 1 Lamotrigine versus placebo, Outcome 1 Greater than 50% reduction in seizure frequency.

Analysis 1.2

Comparison 1 Lamotrigine versus placebo, Outcome 2 Total cessation of seizure frequency.

Analysis 1.3

Comparison 1 Lamotrigine versus placebo, Outcome 3 Proportion of individuals who withdrew from treatment.

Analysis 1.4

Comparison 1 Lamotrigine versus placebo, Outcome 4 Proportion of individuals experience any side effects.

Comparison 1. Lamotrigine versus placebo

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Greater than 50% reduction in seizure frequency Show forest plot	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only

2 Total cessation of seizure frequency Show forest plot	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only

3 Proportion of individuals who withdrew from treatment Show forest plot	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only

4 Proportion of individuals experience any side effects Show forest plot	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only

Comparison 1. Lamotrigine versus placebo