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Comparison 1 Heartburn relief, Outcome 1 Heartburn relief: Prostigmine versus placebo.
Figuras y tablas -
Analysis 1.1

Comparison 1 Heartburn relief, Outcome 1 Heartburn relief: Prostigmine versus placebo.

Comparison 1 Heartburn relief, Outcome 2 Heartburn relief: Mylanta (antacid ‐ magnesium and aluminium hydroxide and simethicone) versus placebo preparation.
Figuras y tablas -
Analysis 1.2

Comparison 1 Heartburn relief, Outcome 2 Heartburn relief: Mylanta (antacid ‐ magnesium and aluminium hydroxide and simethicone) versus placebo preparation.

Comparison 1 Heartburn relief, Outcome 3 Pain intensity after one week: Antacid plus ranitidine versus antacid alone.
Figuras y tablas -
Analysis 1.3

Comparison 1 Heartburn relief, Outcome 3 Pain intensity after one week: Antacid plus ranitidine versus antacid alone.

Comparison 1 Heartburn relief, Outcome 4 Pain intensity after two weeks: Antacid plus ranitidine versus antacid alone.
Figuras y tablas -
Analysis 1.4

Comparison 1 Heartburn relief, Outcome 4 Pain intensity after two weeks: Antacid plus ranitidine versus antacid alone.

Comparison 1. Heartburn relief

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Heartburn relief: Prostigmine versus placebo Show forest plot

1

100

Risk Ratio (M‐H, Fixed, 95% CI)

0.4 [0.23, 0.69]

2 Heartburn relief: Mylanta (antacid ‐ magnesium and aluminium hydroxide and simethicone) versus placebo preparation Show forest plot

1

156

Risk Ratio (M‐H, Fixed, 95% CI)

1.41 [1.18, 1.68]

3 Pain intensity after one week: Antacid plus ranitidine versus antacid alone Show forest plot

1

30

Mean Difference (IV, Fixed, 95% CI)

‐0.31 [‐1.89, 1.27]

4 Pain intensity after two weeks: Antacid plus ranitidine versus antacid alone Show forest plot

1

30

Mean Difference (IV, Fixed, 95% CI)

‐2.13 [‐4.37, 0.11]

Figuras y tablas -
Comparison 1. Heartburn relief