1 Number patients who had successful TWOC Show forest plot

5

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

1.1 Alpha blocker versus placebo

5

685

Risk Ratio (M‐H, Fixed, 95% CI)

1.39 [1.18, 1.64]

1.2 Alfuzosin versus placebo

4

544

Risk Ratio (M‐H, Fixed, 95% CI)

1.31 [1.10, 1.56]

1.3 Tamsulosin versus placebo

1

141

Risk Ratio (M‐H, Fixed, 95% CI)

1.86 [1.17, 2.97]

2 Number of patients with adverse events Show forest plot

5

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

2.1 with recurrent urinary retention

1

141

Risk Ratio (M‐H, Fixed, 95% CI)

0.70 [0.54, 0.91]

2.2 with mean post‐void residual volume greater than 150ml

1

34

Risk Ratio (M‐H, Fixed, 95% CI)

0.82 [0.16, 4.24]

2.3 with alpha blocker side effects

3

582

Risk Ratio (M‐H, Fixed, 95% CI)

1.13 [0.69, 1.85]

2.4 with serious alpha blocker side effects

1

360

Risk Ratio (M‐H, Fixed, 95% CI)

0.77 [0.13, 4.54]

2.5 drop out rate due to alpha blocker side effects

4

627

Risk Ratio (M‐H, Fixed, 95% CI)

1.19 [0.70, 2.02]

2.6 number of people who needed to be recatheterised

5

685

Risk Ratio (M‐H, Fixed, 95% CI)

0.73 [0.63, 0.85]