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Cochrane Database of Systematic Reviews

Aspirina, antiinflamatorios esteroides y no esteroides para el tratamiento de la enfermedad de Alzheimer

Información

DOI:
https://doi.org/10.1002/14651858.CD006378.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 15 febrero 2012see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Demencia y trastornos cognitivos

Copyright:
  1. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Autores

  • Darin Jaturapatporn

    Correspondencia a: Department of Family Medicine, Ramathibodi Hospital, Mahidol University, Bangkok and Baycrest Centre for Geriatric Care, University of Toronto, Toronto, Canada

    [email protected]

  • Mokhtar Gad El Kareem Nasr Isaac

    Old Age Psychiatry, Sussex Partnership NHS Foundation Trust, Eastbourne, UK

  • Jenny McCleery

    Cochrane Dementia and Cognitive Improvement Group, University of Oxford, Oxford, UK

  • Naji Tabet

    Institute of Postgraduate Medicine, Brighton and Sussex Medical School & Cognitive Treatment and Research Unit, Sussex Partnership NHS Foundation Trust, Brighton, UK

Contributions of authors

DJ: Wrote, coordinated, searched and selected trials for inclusion in this review. Also extracted, interpreted and entered data on to RevMan.

MI and NT: contributed to trial searches, obtained copies of trial reports and assessed trials for inclusion/exclusion. They also were involved in data extraction and interpretation, and providing general advice on the review

JMcC: contributed to design of analysis, data interpretation and drafting of review

Contact editors: Leon Flicker and Gordon Wilcock
Consumer editor: Lynne Ramsay

Sources of support

Internal sources

  • New Source of support, Not specified.

External sources

  • No sources of support supplied

Declarations of interest

All authors declare no conflict of interest in this research project.

Acknowledgements

The authors wish to thank the consumer editor, Lynne Ramsay and Ruth Chandler, for their helpful comments. We wish to acknowledge the contribution of Rebecca Quinn as the writer of the protocol of this review. We also wish to thank Dr. Helen Collins. We want to express our thanks for the support of the Cochrane dementia and cognitive improvement group for their help coordinating this project.

We thank Dr. Wanruchada Katchamart, Dr. Paula A. Rochon, Dr. Sunila Kalkar and Wei Wu for their practical advice for the review. We also thank Wei Wu for extracting data and filling the translation sheet for the 2 Chinese studies. We thank Ms. Reem Malouf for statistical advice, Dr. Kittphon Nagaviroj for the PDF file for full text assessment form and Inez Kost and Rita Shaughnessy, the librarians at University of Toronto who helped with the article findings and search term respectively.

Version history

Published

Title

Stage

Authors

Version

2012 Feb 15

Aspirin, steroidal and non‐steroidal anti‐inflammatory drugs for the treatment of Alzheimer's disease

Review

Darin Jaturapatporn, Mokhtar Gad El Kareem Nasr Isaac, Jenny McCleery, Naji Tabet

https://doi.org/10.1002/14651858.CD006378.pub2

2007 Jan 24

Aspirin and anti‐inflammatory drugs for Alzheimer's disease

Protocol

Rebecca Davis, Mokhtar Gad El Kareem Nasr Isaac, Naji Tabet

https://doi.org/10.1002/14651858.CD006378

Differences between protocol and review

1) Background about steroidal anti‐inflammatory drugs was added in the review.

2) Inclusion criteria was adjusted to include any types of RCT and not only double‐blinded

3) Two reviewers (DJ, MI) instead of 3 reviewers independently examined the titles and abstracts of the trials identified in the search and considered them for inclusion according to the pre‐determined eligibility criteria. Any disparity was resolved by retrieval of the cited articles and further discussion with the third reviewer (NT).

4) Review topic was changed from aspirin and anti‐inflammatory agents for Alzheimer’s disease to aspirin, steroidal and non‐steroidal anti‐inflammatory agents for Alzheimer’s disease.

5) Data was not extracted independently by two authors. The first author extracted the data and this was followed by verification by a second author.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.