Appendix 1. MEDLINE search strategy

#1 explode "Glaucoma‐" / surgery
#2 explode "Filtering‐Surgery" / all subheadings
#3 "intraocular‐pressure"/ all subheadings
#4 ( ((glaucoma or filter* or filtrat*) near surg*) in AB )or( ((glaucoma or filter* or filtrat*) near surg*) in TI )
#5 ( (trabeculectom* or sclerostom*) in AB ) or ( (trabeculectom* or sclerostom*) in TI )
#6 ((intraocular‐pressure near surg*) in AB) or ((intraocular‐pressure near surg*) in TI)
#7 #1 or #2 or #3 or #4 or #5 or #6
#8 explode "Antimetabolites‐" / all subheadings
#9 explode "Antibiotics‐Antineoplastic" / all subheadings
#10 ( (anti?metabolite* or anti?neoplastic* ) in AB )or( (anti?metabolite* or anti?neoplastic* ) in TI )
#11 explode "fluorouracil"/ all subheadings
#12 explode "mitomycins"/ all subheadings
#13 ( (amet?cin? or mitoc?n c or m?tom?cin? c or mmc or mutamycin or "nsc 26980") in AB )or( (amet?cin? or mitoc?n c or m?tom?cin? c or mmc or mutamycin or "nsc 26980") in TI )
#14 ( (fluoro uracil or fluro?uracil or fluorouracil or 5?fu or accusite adrucil or effluderm or efud?x or f6627 or fluoroblastin or fluoroplex or fluoro uracil or fluoro?uracil or fluoruracil or fluouracil or fluracedyl or fluracil or fluracilium or flu) in AB )or( (fluoro uracil or fluro?uracil or fluorouracil or 5?fu or accusite adrucil or effluderm or efud?x or f6627 or fluoroblastin or fluoroplex or fluoro uracil or fluoro?uracil or fluoruracil or fluouracil or fluracedyl or fluracil or fluracilium or flu) in TI )
#15 #8 or #9 or #10 or #11 or #12 or #13 or #14
#16 #7 and #15

We will combine this search with the Cochrane Highly Sensitive Search Strategy phases 1 and 2 as set out in the Cochrane Handbook for Systematic Reviews of Interventions (Higgins 2005a).