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Comparison 1 Enteral taurine supplementation versus no supplementation, Outcome 1 Growth during trial period.
Figuras y tablas -
Analysis 1.1

Comparison 1 Enteral taurine supplementation versus no supplementation, Outcome 1 Growth during trial period.

Comparison 1 Enteral taurine supplementation versus no supplementation, Outcome 2 Intestinal fat absorption (percentage of total intake).
Figuras y tablas -
Analysis 1.2

Comparison 1 Enteral taurine supplementation versus no supplementation, Outcome 2 Intestinal fat absorption (percentage of total intake).

Comparison 1 Enteral taurine supplementation versus no supplementation, Outcome 3 Electroretinography.
Figuras y tablas -
Analysis 1.3

Comparison 1 Enteral taurine supplementation versus no supplementation, Outcome 3 Electroretinography.

Comparison 1 Enteral taurine supplementation versus no supplementation, Outcome 4 Auditory brainstem‐evoked responses.
Figuras y tablas -
Analysis 1.4

Comparison 1 Enteral taurine supplementation versus no supplementation, Outcome 4 Auditory brainstem‐evoked responses.

Comparison 1 Enteral taurine supplementation versus no supplementation, Outcome 5 Neonatal mortality.
Figuras y tablas -
Analysis 1.5

Comparison 1 Enteral taurine supplementation versus no supplementation, Outcome 5 Neonatal mortality.

Comparison 1 Enteral taurine supplementation versus no supplementation, Outcome 6 Incidence of necrotising enterocolitis.
Figuras y tablas -
Analysis 1.6

Comparison 1 Enteral taurine supplementation versus no supplementation, Outcome 6 Incidence of necrotising enterocolitis.

Comparison 1. Enteral taurine supplementation versus no supplementation

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Growth during trial period Show forest plot

6

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

1.1 Weight gain during neonatal period (grams/kilogram/day)

3

81

Mean Difference (IV, Fixed, 95% CI)

‐0.64 [‐1.84, 0.56]

1.2 Weight gain until three/four months (grams/kilogram/day)

4

80

Mean Difference (IV, Fixed, 95% CI)

‐0.25 [‐1.16, 0.66]

1.3 Length change during neonatal period (millimetres/week)

1

37

Mean Difference (IV, Fixed, 95% CI)

‐1.0 [‐2.93, 0.93]

1.4 Length change over three/four months (millimetres/week)

4

80

Mean Difference (IV, Fixed, 95% CI)

0.37 [‐0.23, 0.98]

1.5 Head circumference change during neonatal period (millimetres/week)

1

37

Mean Difference (IV, Fixed, 95% CI)

0.0 [‐1.03, 1.03]

1.6 Head circumference change over three/four months (millimetres/week)

4

80

Mean Difference (IV, Fixed, 95% CI)

0.15 [‐0.19, 0.50]

2 Intestinal fat absorption (percentage of total intake) Show forest plot

4

42

Mean Difference (IV, Fixed, 95% CI)

4.00 [1.43, 6.58]

3 Electroretinography Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

3.1 Cornea negative potential‐ latency (milliseconds)

1

32

Mean Difference (IV, Fixed, 95% CI)

0.40 [‐0.92, 1.72]

3.2 Cornea negative potential‐ amplitude (microVolts)

1

32

Mean Difference (IV, Fixed, 95% CI)

‐1.70 [‐4.23, 0.83]

3.3 Cornea positive potential‐ latency (milliseconds)

1

32

Mean Difference (IV, Fixed, 95% CI)

‐0.20 [‐2.73, 2.33]

3.4 Cornea positive potential‐ amplitude (microVolts)

1

32

Mean Difference (IV, Fixed, 95% CI)

‐3.10 [‐9.06, 2.86]

4 Auditory brainstem‐evoked responses Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

4.1 Wave I latency (milliseconds): 20/second

1

32

Mean Difference (IV, Fixed, 95% CI)

‐0.20 [‐0.63, 0.23]

4.2 Wave I latency (milliseconds): 67/second

1

32

Mean Difference (IV, Fixed, 95% CI)

‐0.5 [‐0.93, ‐0.07]

4.3 Wave III latency (milliseconds): 20/second

1

32

Mean Difference (IV, Fixed, 95% CI)

‐0.30 [‐0.62, 0.02]

4.4 Wave III latency (milliseconds): 67/second

1

32

Mean Difference (IV, Fixed, 95% CI)

‐0.20 [‐0.56, 0.16]

4.5 Wave V latency (milliseconds): 20/second

1

32

Mean Difference (IV, Fixed, 95% CI)

‐0.20 [‐0.70, 0.30]

4.6 Wave V latency (milliseconds): 67/second

1

32

Mean Difference (IV, Fixed, 95% CI)

‐0.30 [‐0.73, 0.13]

5 Neonatal mortality Show forest plot

1

47

Risk Ratio (M‐H, Fixed, 95% CI)

0.35 [0.01, 8.11]

6 Incidence of necrotising enterocolitis Show forest plot

1

47

Risk Ratio (M‐H, Fixed, 95% CI)

3.13 [0.35, 27.96]

Figuras y tablas -
Comparison 1. Enteral taurine supplementation versus no supplementation