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Cochrane Database of Systematic Reviews

Restricción de líquidos para el tratamiento de lactantes prematuros con enfermedad pulmonar crónica

Información

DOI:
https://doi.org/10.1002/14651858.CD005389.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 08 febrero 2017see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:

  1. Grupo Cochrane de Neonatología

Copyright:
  1. Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Citado por:

Citado 0 veces por enlace Crossref Cited-by

Contraer

Autores

  • Keith J Barrington

    Correspondencia a: Department of Pediatrics, CHU Ste‐Justine, Montreal, Canada

    [email protected]

  • Etienne Fortin‐Pellerin

    Department of Neonatology, Sainte Justine University Health Center, Montreal, Canada

  • Thomas Pennaforte

    Université de Montréal, Montreal, Canada

Contributions of authors

KB designed the protocol and wrote the first draft.

All three authors reviewed the articles found by the literature search.

All three authors edited the review.

Sources of support

Internal sources

  • No sources of support supplied

External sources

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, USA.

    Editorial support of the Cochrane Neonatal Review Group has been funded with Federal funds from the Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USA, under Contract No. HHSN275201600005C

Declarations of interest

None.

Version history

Published

Title

Stage

Authors

Version

2017 Feb 08

Fluid restriction for treatment of preterm infants with chronic lung disease

Review

Keith J Barrington, Etienne Fortin‐Pellerin, Thomas Pennaforte

https://doi.org/10.1002/14651858.CD005389.pub2

2005 Jul 20

Fluid restriction for treatment of preterm babies with chronic lung disease

Protocol

Keith J Barrington, Fahad N Al‐Hazzani

https://doi.org/10.1002/14651858.CD005389

Differences between protocol and review

The search strategy was updated to include a search of CINAHL and clinical trial registries.

The methods for the assessment of risk of bias were altered to match current Cochrane standards.

We added the methodology and plan for 'Summary of findings' tables and GRADE recommendations, which were not included in the original protocol.

Keywords

MeSH

Medical Subject Headings (MeSH) Keywords

Medical Subject Headings Check Words

Humans; Infant, Newborn;

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.

Study flow diagram.
Figuras y tablas -
Figure 1

Study flow diagram.

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Comparison 1 Fluid restricted compared to liberal fluids, Outcome 1 Duration of hospitalisation.
Figuras y tablas -
Analysis 1.1

Comparison 1 Fluid restricted compared to liberal fluids, Outcome 1 Duration of hospitalisation.

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Comparison 1 Fluid restricted compared to liberal fluids, Outcome 2 Daily weight gain.
Figuras y tablas -
Analysis 1.2

Comparison 1 Fluid restricted compared to liberal fluids, Outcome 2 Daily weight gain.

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Comparison 1 Fluid restricted compared to liberal fluids, Outcome 3 Proportion with apnoea.
Figuras y tablas -
Analysis 1.3

Comparison 1 Fluid restricted compared to liberal fluids, Outcome 3 Proportion with apnoea.

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Summary of findings for the main comparison. Fluid restricted compared to liberal fluids compared to placebo for treatment of preterm babies with chronic lung disease

Fluid restricted compared to liberal fluids compared to placebo for treatment of preterm babies with chronic lung disease

Participant or population: treatment of preterm babies with chronic lung disease
Setting:
Intervention: Fluid restricted compared to liberal fluids
Comparison: placebo

Outcomes

Anticipated absolute effects* (95% CI)

Relative effect
(95% CI)

№ of participants
(studies)

Quality of the evidence
(GRADE)

Comments

Risk with placebo

Risk with fluid restricted compared to liberal fluids

Duration of oxygen therapy

The mean duration of oxygen therapy was 27.5 days

median 0.5 days higher
(0 to 0 )

‐

60
(1 RCT)

⊕⊕⊝⊝
LOW 1 2

Duration of hospitalisation

The mean duration of hospitalisation was 85 days

MD 3 Days higher
(7.64 lower to 13.64 higher)

‐

60
(1 RCT)

⊕⊕⊝⊝
LOW 1 2

Daily weight gain

The mean daily weight gain was 14.8 g/kg/d

MD 0.5 g/kg/d higher
(1.22 lower to 2.22 higher)

‐

60
(1 RCT)

⊕⊕⊝⊝
LOW 1 2

Proportion with apnoea

Study population

RR 1.35
(0.98 to 1.86)

60
(1 RCT)

⊕⊕⊝⊝
LOW 1 2

630 per 1000

850 per 1000
(617 to 1000)

Moderate

630 per 1000

850 per 1000
(617 to 1000)

*The risk in the intervention group (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).

CI: Confidence interval; RR: Risk ratio; OR: Odds ratio

GRADE Working Group grades of evidence
High quality: We are very confident that the true effect lies close to that of the estimate of the effect
Moderate quality: We are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low quality: Our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect
Very low quality: We have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect

1 Unmasked study

2 Wide confidence limits

Figuras y tablas -
Summary of findings for the main comparison. Fluid restricted compared to liberal fluids compared to placebo for treatment of preterm babies with chronic lung disease
Ir a la tabla de la revisión
Comparison 1. Fluid restricted compared to liberal fluids

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Duration of hospitalisation Show forest plot

1

60

Mean Difference (IV, Fixed, 95% CI)

3.0 [‐7.64, 13.64]

2 Daily weight gain Show forest plot

1

60

Mean Difference (IV, Fixed, 95% CI)

0.5 [‐1.22, 2.22]

3 Proportion with apnoea Show forest plot

1

60

Risk Difference (M‐H, Fixed, 95% CI)

0.22 [‐0.00, 0.44]
Figuras y tablas -
Comparison 1. Fluid restricted compared to liberal fluids
Ir a la tabla de la revisión