Intragastric balloon for obesity

Marcos AP Fernandes; Álvaro N Atallah; Bernardo Soares; Humberto Saconato; Sandra M Guimarães; Delcio Matos; Larissa R Carneiro Monteiro; Bernd Richter

doi:10.1002/14651858.CD004931.pub2

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Analysis 1.1

Comparison 1 Intragastric balloon versus diet, Outcome 1 Weight loss in kg.

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Analysis 2.1

Comparison 2 Intragastric balloon versus no treatment, Outcome 1 Weight loss in kg.

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Analysis 3.1

Comparison 3 Intragastric balloon versus intragastric balloon + diet, Outcome 1 Weight loss in kg.

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Analysis 4.1

Comparison 4 Intragastric balloon + diet versus diet only, Outcome 1 Weight loss in kg.

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Analysis 5.1

Comparison 5 Minor complications due to balloon usage, Outcome 1 Gastric ulcers.

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Analysis 5.2

Comparison 5 Minor complications due to balloon usage, Outcome 2 Gastric erosions.

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Analysis 5.3

Comparison 5 Minor complications due to balloon usage, Outcome 3 Abdominal pain.

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Analysis 5.4

Comparison 5 Minor complications due to balloon usage, Outcome 4 Vomiting.

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Analysis 6.1

Comparison 6 Major complications due to balloon usage, Outcome 1 Migration of deflated balloon.

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Analysis 6.2

Comparison 6 Major complications due to balloon usage, Outcome 2 Small bowel obstruction.

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Analysis 6.3

Comparison 6 Major complications due to balloon usage, Outcome 3 Mallory‐Weiss tears.

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Analysis 6.4

Comparison 6 Major complications due to balloon usage, Outcome 4 Oesophageal laceration.

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Comparison 1. Intragastric balloon versus diet

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Weight loss in kg Show forest plot	2	61	Mean Difference (IV, Fixed, 95% CI)	3.49 [2.75, 4.23]

Comparison 1. Intragastric balloon versus diet

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Comparison 2. Intragastric balloon versus no treatment

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Weight loss in kg Show forest plot	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected

Comparison 2. Intragastric balloon versus no treatment

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Comparison 3. Intragastric balloon versus intragastric balloon + diet

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Weight loss in kg Show forest plot	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected

Comparison 3. Intragastric balloon versus intragastric balloon + diet

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Comparison 4. Intragastric balloon + diet versus diet only

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Weight loss in kg Show forest plot	5	158	Mean Difference (IV, Fixed, 95% CI)	‐0.04 [‐0.44, 0.35]

Comparison 4. Intragastric balloon + diet versus diet only

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Comparison 5. Minor complications due to balloon usage

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Gastric ulcers Show forest plot	6	449	Risk Ratio (M‐H, Fixed, 95% CI)	4.91 [1.57, 15.35]

2 Gastric erosions Show forest plot	6	489	Risk Ratio (M‐H, Fixed, 95% CI)	9.78 [3.87, 24.69]

3 Abdominal pain Show forest plot	4	272	Risk Ratio (M‐H, Fixed, 95% CI)	14.0 [3.45, 56.74]

4 Vomiting Show forest plot	2	196	Risk Ratio (M‐H, Fixed, 95% CI)	4.33 [0.81, 23.21]

Comparison 5. Minor complications due to balloon usage

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Comparison 6. Major complications due to balloon usage

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Migration of deflated balloon Show forest plot	2	54	Risk Ratio (M‐H, Fixed, 95% CI)	2.67 [0.30, 24.01]

2 Small bowel obstruction Show forest plot	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected

3 Mallory‐Weiss tears Show forest plot	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected

4 Oesophageal laceration Show forest plot	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected

Comparison 6. Major complications due to balloon usage

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