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Cochrane Database of Systematic Reviews

Ácido fólico con o sin vitamina B12 para la prevención y el tratamiento de personas sanas de edad avanzada con demencia

Información

DOI:
https://doi.org/10.1002/14651858.CD004514.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 08 octubre 2008see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:

  1. Grupo Cochrane de Demencia y trastornos cognitivos

Copyright:
  1. Copyright © 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Contraer

Autores

  • Reem Malouf

    Correspondencia a: Cochrane Dementia and Cognitive Improvement Group, Oxford, UK

    [email protected]

  • John Grimley Evans

    Division of Clinical Geratology, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK

Contributions of authors

‐RM‐ contact author, collection of studies, assessment of studies, data extraction and input into Revman, writing the review
‐JGE‐ co‐reviewer, assessment of studies, co‐drafting of text

‐Dymphna Hermans: original search and update searches; Vittoria Lutje, 2008 update search
‐The review was peer reviewed anonymously in April 2008

Sources of support

Internal sources

  • Division of Clinical Geratology, Nuffield Department of Clinical Medicine, University of Oxford, UK.

  • Alzheimer's Society, UK.

External sources

  • National Health Service, Research and Development, UK.

  • Alzheimer's Society, UK.

Declarations of interest

None known

Acknowledgements

We thank Almudena Areosa Sastre for her work on the protocol and the first version of the review (selection of studies for inclusion and checking drafts). We thank Dr. Robert Clarke for providing original data from the VITAL trial and Dr Bryan for providing the data requested. We are also grateful to Corinne Cavender as consumer editor of the first version of the review. We wish to thank the following consumer editors for their comment on the latest update of this review: Ann E. Finfa, Morio Aihara and U. Hla Htay.

Version history

Published

Title

Stage

Authors

Version

2008 Oct 08

Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people

Review

Reem Malouf, John Grimley Evans

https://doi.org/10.1002/14651858.CD004514.pub2

2003 Oct 20

Folic acid with or without vitamin B12 for cognition and dementia

Review

Reem Malouf, John Grimley Evans, Almudena Areosa Sastre

https://doi.org/10.1002/14651858.CD004514

Differences between protocol and review

None

Notes

This review and the following review on Vitamin B12 for cognition will be combined into a single review on Folate and B vitamins for the prevention and treatment of dementia. New searches will be run, and the reviewers anticipate completion of the combined updated review for issue 3/2009.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.