Scolaris Content Display Scolaris Content Display

Study flow diagram.
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Figure 1

Study flow diagram.

'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
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Figure 2

'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.

'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.
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Figure 3

'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.

Comparison 1 Any antibiotics versus placebo or no treatment, Outcome 1 Endometritis.
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Analysis 1.1

Comparison 1 Any antibiotics versus placebo or no treatment, Outcome 1 Endometritis.

Comparison 1 Any antibiotics versus placebo or no treatment, Outcome 2 Maternal length of stay.
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Analysis 1.2

Comparison 1 Any antibiotics versus placebo or no treatment, Outcome 2 Maternal length of stay.

Summary of findings for the main comparison. Any antibiotics versus placebo or no treatment for operative vaginal delivery

Any antibiotics versus placebo or no treatment for operative vaginal delivery

Population: women undergoing operative vaginal delivery
Settings: a hospital in USA
Intervention: any antibiotics

Comparison: placebo or no treatment

Outcomes

Illustrative comparative risks* (95% CI)

Relative effect
(95% CI)

No of participants
(studies)

Quality of the evidence
(GRADE)

Comments

Assumed risk

Corresponding risk

Control

Any antibiotics versus placebo or no treatment

Endometritis

Study population

RR 0.07
(0 to 1.21)

393
(1 study)

⊕⊕⊝⊝
low1

35 per 1000

2 per 1000
(0 to 42)

Moderate

35 per 1000

2 per 1000
(0 to 42)

Maternal length of hospital stay (days)

The mean maternal length of stay in the intervention groups was
0.09 higher
(0.23 lower to 0.41 higher)

393
(1 study)

⊕⊕⊝⊝
low1

Fever

Not estimable

0 (no study)

See comment

This outcome was not reported in the one included study.

Infected episiotomy/perineal/vaginal laceration

Not estimable

0 (no study)

See comment

This outcome was not reported in the one included study.

Urinary tract infection

Not estimable

0 (no study)

See comment

This outcome was not reported in the one included study.

Serious infectious complications

Not estimable

0 (no study)

See comment

This outcome was not reported in the one included study.

Maternal adverse reactions

Not estimable

0 (no study)

See comment

This outcome was not reported in the one included study.

*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: Confidence interval; RR: Risk ratio;

GRADE Working Group grades of evidence
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: We are very uncertain about the estimate.

1 Wide confidence interval crossing the line of no effect, few events and a small sample size.

Figuras y tablas -
Summary of findings for the main comparison. Any antibiotics versus placebo or no treatment for operative vaginal delivery
Comparison 1. Any antibiotics versus placebo or no treatment

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Endometritis Show forest plot

1

393

Risk Ratio (M‐H, Fixed, 95% CI)

0.07 [0.00, 1.21]

2 Maternal length of stay Show forest plot

1

393

Mean Difference (IV, Fixed, 95% CI)

0.09 [‐0.23, 0.41]

Figuras y tablas -
Comparison 1. Any antibiotics versus placebo or no treatment