Scolaris Content Display Scolaris Content Display

Cochrane Database of Systematic Reviews

Intervenciones prenatales para la trombocitopenia aloinmune fetomaterna

Información

DOI:
https://doi.org/10.1002/14651858.CD004226.pub3Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 11 mayo 2011see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:

  1. Grupo Cochrane de Embarazo y parto

Copyright:
  1. Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

Altmetric:

Citado por:

Citado 0 veces por enlace Crossref Cited-by

Contraer

Autores

  • Rachel Rayment

    Correspondencia a: Arthur Bloom Haemophilia Centre, University Hospital of Wales, Cardiff, UK

    [email protected]

  • Susan J Brunskill

    Systematic Review Initiative, NHS Blood and Transplant, Oxford, UK

  • Peter W Soothill

    Department of Clinical Medicine, Division of Obstetrics and Gynaecology, St Michael's Hospital, Bristol, UK

  • David J Roberts

    Systematic Review Initiative, NHS Blood and Transplant, Oxford, UK

  • James B Bussel

    Weill Cornell Medical College, The New York Presbyterian Hospital, New York, USA

  • Michael F Murphy

    Systematic Review Initiative, NHS Blood and Transplant, Oxford, UK

Contributions of authors

Rachel Rayment (RR) prepared the first draft of the protocol that was then reviewed and edited by Peter Soothill (PS), David Roberts (DR) James Bussel (JB) and Mike Murphy (MM).

RR and Susan Brunskill (SB) undertook additional searching and the selection of studies, eligibility and quality assessment, data extraction and analysis for the review and subsequent update.

RR, SB, DR, MM, Jim Bussel (JB) and PS contributed to the preparation of the final draft of the review for the original review and RR, SB, MM, JB and PS contributed to the preparation of the final draft for this update.

Sources of support

Internal sources

  • National Blood Service, Research and Development, UK.

External sources

  • No sources of support supplied

Declarations of interest

James Bussel has received unrestricted support of clinical research, including staff, over the past four years from IgG of America. He is an author on several of the studies assessed for inclusion in this review and the author of one of the included studies. James Bussel was not involved in the assessment of his studies for the review.

Acknowledgements

We thank Lynn Hampson for her search of the Cochrane Pregnancy and Childbirth Group's Specialised Register. We thank Jon Deeks and Phil Alderson for their advice and comments on the methods section of this review and Simon Stanworth (SS) for verifying the data extraction and data entry for discrepancies ahead of the first publication of this review.

Version history

Published

Title

Stage

Authors

Version

2011 May 11

Antenatal interventions for fetomaternal alloimmune thrombocytopenia

Review

Rachel Rayment, Susan J Brunskill, Peter W Soothill, David J Roberts, James B Bussel, Michael F Murphy

https://doi.org/10.1002/14651858.CD004226.pub3

2005 Jan 24

Antenatal interventions for fetomaternal alloimmune thrombocytopenia

Review

Rachel Rayment, Susan J Brunskill, Peter W Soothill, David J Roberts, James B Bussel, Michael F Murphy

https://doi.org/10.1002/14651858.CD004226.pub2

2003 Apr 22

Antenatal interventions for fetomaternal alloimmune thrombocytopenia

Protocol

Rachel Rayment, David J Roberts, Michael F Murphy

https://doi.org/10.1002/14651858.CD004226

Differences between protocol and review

In addition to the outcomes that we prespecified, there were a number of outcomes that the trials reported data for that were of significant interest to this systematic review. These non‐prespecified outcomes are reported at the end of the results section as "Outcomes not prespecified in the protocol". The outcomes are as follows.

  • Satisfactory response to therapy.

  • Mean change in fetal platelet count between first and second FBS.

  • Mean change in fetal platelet count between pre‐treatment and fetal birth platelet count.

  • Mean change in fetal platelet count at birth from first fetal blood sampling.

  • Number of ICHs in previous sibling.

  • Adverse outcomes associated with FBS.

  • Adverse outcomes associated with treatment.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.