Terapia de compresión para el tratamiento del síndrome postrombótico en etapas I y II (Widmer)
Referencias
Referencias de los estudios incluidos en esta revisión
Referencias de los estudios excluidos de esta revisión
Referencias adicionales
Characteristics of studies
Characteristics of included studies [ordered by study ID]
Ir a:
| Methods | Randomised, crossover design with independent blinded assessment of the outcome events. Method of randomisation: Computer generated randomisation schedule. Exclusions post‐randomisation: none. Losses to follow up: none. Study duration: 2 months. | |
| Participants | Country: Canada. Setting: Ontario teaching hospital. No. of participants: 15. Gender: 12 women and 3 men. Age: mean age 60 (range 38 to 81. Inclusion criteria: documented DVT and intractable symptoms of PPS causing significant limitation of lifestyle, significant morbidity or both, as indicated by any of the following: loss of job or absenteeism from work because of PPS; interference with day‐to day activities, e.g. housework, sports; frequent loss of sleep; failure of condition to improve with use of graduated compression stockings; or person's intolerance of, or refusal to use such stockings. Exclusion criteria: DVT within the past 3 months or if they were unable to travel to the clinic. | |
| Interventions | Extremity pump twice daily (20 minutes per session) randomly assigned to use either 50 mm Hg pressure or 15 mm Hg pressure for the first month, the other pressure was used the second month. | |
| Outcomes | Successful treatment: defined as preferring the high pressure, and continuing the use of the extremity pump and difference between the two pressures of at least slight importance. | |
| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | Low risk | A ‐ Adequate |
| Methods | Randomised, double blind study. Participant and outcome assessor blinded. Method of randomisation: Not stated. Exclusions post‐randomisation: none described. Losses to follow up: one in treatment group due to death. Follow up was done every 3 months. | |
| Participants | Country: Canada. Setting: affiliated hospitals, Hamilton University, Ontario Canada. No. of participants: 35. Age: mean (range) years: Gender: (% women): Inclusion criteria: symptomatic DVT. Evaluation was done one year after proximal DVT. PPS was defined as chronic pain and swelling as scored on a standardized questionnaire. Exclusion criteria: previous graduated compression stockings, geographic inaccessibility and failure to provide informed consent. | |
| Interventions | Comparison was done with compression stockings (30‐40 mm Hg) or placebo stockings (one to two sizes too large). Calf length or thigh length compression stockings were administered depending on the localisation of complaints. | |
| Outcomes | Treatment failure: defined as pain and swelling that did not improve, or worsened after the first three months, or if these symptoms worsened during further follow up, or if a patient could not perform his daily activities for five or more days in any three‐month period, or developed a leg ulcer. Mean follow up: treatment group =25.6 months, | |
| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | Low risk | A ‐ Adequate |
CLCS calf length compression stockings
CLPS calf length placebo stockings
DVT deep vein thrombosis
PPS post‐phlebitic syndrome
TLCS thigh length compression stockings
TLPS thigh length placebo stockings
Characteristics of excluded studies [ordered by study ID]
Ir a:
| Study | Reason for exclusion |
| Crossover study to evaluate the effect of graduated elastic compression stockings on leg symptoms and signs during exercise in patients who had had a deep vein thrombosis one year previously. Artificial situation with treadmill exercise session with and without stockings. | |
| Study was not a treatment for post‐thrombotic syndrome but designed to test the effectiveness of a new intermittent pneumatic compression system. |
Data and analyses
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 No improvement or deterioration of post‐thrombotic syndrome Show forest plot | 1 | Odds Ratio (M‐H, Fixed, 95% CI) | Subtotals only | |
| Analysis 1.1  Comparison 1 Treatment failure, Outcome 1 No improvement or deterioration of post‐thrombotic syndrome. | ||||
Comparison 1 Treatment failure, Outcome 1 No improvement or deterioration of post‐thrombotic syndrome.
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 No improvement or deterioration of post‐thrombotic syndrome Show forest plot | 1 | Odds Ratio (M‐H, Fixed, 95% CI) | Subtotals only | |
