Scolaris Content Display Scolaris Content Display

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 1 Number of women with prolapse symptoms (subjective failure).
Figuras y tablas -
Analysis 1.1

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 1 Number of women with prolapse symptoms (subjective failure).

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 2 Number of women with any prolapse (objective failure).
Figuras y tablas -
Analysis 1.2

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 2 Number of women with any prolapse (objective failure).

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 3 Number of women with recurrent vault prolapse (objective).
Figuras y tablas -
Analysis 1.3

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 3 Number of women with recurrent vault prolapse (objective).

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 4 Number of women unsatisfied with surgery.
Figuras y tablas -
Analysis 1.4

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 4 Number of women unsatisfied with surgery.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 5 Number of women with post‐operative stress urinary incontinence.
Figuras y tablas -
Analysis 1.5

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 5 Number of women with post‐operative stress urinary incontinence.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 6 Number of women with urgency, detrusor overactivity or overactive bladder.
Figuras y tablas -
Analysis 1.6

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 6 Number of women with urgency, detrusor overactivity or overactive bladder.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 7 Number of women with de novo (new) urgency, detrusor overactivity or overactive bladder.
Figuras y tablas -
Analysis 1.7

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 7 Number of women with de novo (new) urgency, detrusor overactivity or overactive bladder.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 8 Number of women with persistent voiding dysfunction.
Figuras y tablas -
Analysis 1.8

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 8 Number of women with persistent voiding dysfunction.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 9 Number of women with new voiding dysfunction.
Figuras y tablas -
Analysis 1.9

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 9 Number of women with new voiding dysfunction.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 10 Number of women with constipation.
Figuras y tablas -
Analysis 1.10

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 10 Number of women with constipation.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 11 Number of women with faecal incontinence.
Figuras y tablas -
Analysis 1.11

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 11 Number of women with faecal incontinence.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 12 Number of women with obstructed defecation.
Figuras y tablas -
Analysis 1.12

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 12 Number of women with obstructed defecation.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 13 Postoperative dyspareunia.
Figuras y tablas -
Analysis 1.13

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 13 Postoperative dyspareunia.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 14 Women with de novo (new) postoperative dyspareunia.
Figuras y tablas -
Analysis 1.14

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 14 Women with de novo (new) postoperative dyspareunia.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 15 Blood loss (ml).
Figuras y tablas -
Analysis 1.15

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 15 Blood loss (ml).

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 16 Postoperative decrease in Hb (gm/dl).
Figuras y tablas -
Analysis 1.16

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 16 Postoperative decrease in Hb (gm/dl).

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 17 Operating time (minutes).
Figuras y tablas -
Analysis 1.17

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 17 Operating time (minutes).

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 18 Length of stay in hospital (days).
Figuras y tablas -
Analysis 1.18

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 18 Length of stay in hospital (days).

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 19 Time to return to normal activity (days).
Figuras y tablas -
Analysis 1.19

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 19 Time to return to normal activity (days).

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 20 Cost (US dollars).
Figuras y tablas -
Analysis 1.20

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 20 Cost (US dollars).

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 21 Women having further prolapse surgery.
Figuras y tablas -
Analysis 1.21

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 21 Women having further prolapse surgery.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 22 Women having further continence surgery.
Figuras y tablas -
Analysis 1.22

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 22 Women having further continence surgery.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 23 Women having further prolapse or continence surgery.
Figuras y tablas -
Analysis 1.23

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 23 Women having further prolapse or continence surgery.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 24 Time to recurrence of prolapse (months).
Figuras y tablas -
Analysis 1.24

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 24 Time to recurrence of prolapse (months).

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 25 Adverse events.
Figuras y tablas -
Analysis 1.25

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 25 Adverse events.

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 26 Number of women with recurrent rectocele (objective).
Figuras y tablas -
Analysis 1.26

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 26 Number of women with recurrent rectocele (objective).

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 27 Number of women with recurrent cystocele (objective).
Figuras y tablas -
Analysis 1.27

Comparison 1 Surgery for upper vaginal (vault/uterine) prolapse, Outcome 27 Number of women with recurrent cystocele (objective).

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 1 Number of women with prolapse symptoms (subjective failure).
Figuras y tablas -
Analysis 2.1

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 1 Number of women with prolapse symptoms (subjective failure).

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 2 Number of women with prolapse (objective failure).
Figuras y tablas -
Analysis 2.2

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 2 Number of women with prolapse (objective failure).

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 3 Number of women with anterior prolapse / cystocele (objective failure).
Figuras y tablas -
Analysis 2.3

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 3 Number of women with anterior prolapse / cystocele (objective failure).

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 4 Number of women with posterior prolapse / rectocele (objective failure).
Figuras y tablas -
Analysis 2.4

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 4 Number of women with posterior prolapse / rectocele (objective failure).

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 6 Number of women with pre‐operative stress incontinence not cured.
Figuras y tablas -
Analysis 2.6

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 6 Number of women with pre‐operative stress incontinence not cured.

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 7 Number of women with de novo (new) stress urinary incontinence.
Figuras y tablas -
Analysis 2.7

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 7 Number of women with de novo (new) stress urinary incontinence.

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 8 Number of women with urgency, detrusor overactivity or overactive bladder.
Figuras y tablas -
Analysis 2.8

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 8 Number of women with urgency, detrusor overactivity or overactive bladder.

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 9 Number of women with dyspareunia.
Figuras y tablas -
Analysis 2.9

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 9 Number of women with dyspareunia.

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 10 Operating time (minutes).
Figuras y tablas -
Analysis 2.10

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 10 Operating time (minutes).

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 11 Blood loss (ml).
Figuras y tablas -
Analysis 2.11

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 11 Blood loss (ml).

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 12 Haemoglobin change.
Figuras y tablas -
Analysis 2.12

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 12 Haemoglobin change.

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 13 Time to return to spontaneous voiding (days).
Figuras y tablas -
Analysis 2.13

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 13 Time to return to spontaneous voiding (days).

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 14 Number of women with postoperative complications.
Figuras y tablas -
Analysis 2.14

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 14 Number of women with postoperative complications.

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 15 Length of stay in hospital (days).
Figuras y tablas -
Analysis 2.15

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 15 Length of stay in hospital (days).

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 18 Number of women having further prolapse surgery.
Figuras y tablas -
Analysis 2.18

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 18 Number of women having further prolapse surgery.

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 19 Number of women having further surgery for incontinence.
Figuras y tablas -
Analysis 2.19

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 19 Number of women having further surgery for incontinence.

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 20 Persistent voiding dysfunction.
Figuras y tablas -
Analysis 2.20

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 20 Persistent voiding dysfunction.

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 21 Number of women with worse bowel function.
Figuras y tablas -
Analysis 2.21

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 21 Number of women with worse bowel function.

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 23 Death.
Figuras y tablas -
Analysis 2.23

Comparison 2 One method of anterior prolapse repair versus another surgical method, Outcome 23 Death.

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 1 Number of women with prolapse symptoms (subjective failure).
Figuras y tablas -
Analysis 3.1

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 1 Number of women with prolapse symptoms (subjective failure).

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 2 Number of women with prolapse (objective failure).
Figuras y tablas -
Analysis 3.2

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 2 Number of women with prolapse (objective failure).

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 4 Number of women with faecal incontinence after operation.
Figuras y tablas -
Analysis 3.4

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 4 Number of women with faecal incontinence after operation.

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 5 Number of women with anal incontinence to flatus after operation.
Figuras y tablas -
Analysis 3.5

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 5 Number of women with anal incontinence to flatus after operation.

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 6 Number of women with obstructed defecation / constipation after surgery.
Figuras y tablas -
Analysis 3.6

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 6 Number of women with obstructed defecation / constipation after surgery.

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 7 Number of women with sexual function not improved after operation.
Figuras y tablas -
Analysis 3.7

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 7 Number of women with sexual function not improved after operation.

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 8 Number of women with dyspareunia.
Figuras y tablas -
Analysis 3.8

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 8 Number of women with dyspareunia.

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 9 Blood loss (ml).
Figuras y tablas -
Analysis 3.9

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 9 Blood loss (ml).

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 10 Difference in haemoglobin.
Figuras y tablas -
Analysis 3.10

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 10 Difference in haemoglobin.

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 11 Operating time (minutes).
Figuras y tablas -
Analysis 3.11

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 11 Operating time (minutes).

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 12 Postoperative narcotic (morphine) use.
Figuras y tablas -
Analysis 3.12

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 12 Postoperative narcotic (morphine) use.

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 13 Number of women with postoperative complications.
Figuras y tablas -
Analysis 3.13

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 13 Number of women with postoperative complications.

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 14 Persistent postoperative pain.
Figuras y tablas -
Analysis 3.14

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 14 Persistent postoperative pain.

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 15 Length of stay in hospital (days).
Figuras y tablas -
Analysis 3.15

Comparison 3 One method of posterior prolapse repair versus another surgical method, Outcome 15 Length of stay in hospital (days).

Comparison 7 Prolapse repair and new urinary symptoms, Outcome 1 Number of women with de novo (new) stress urinary incontinence (subjective diagnosis).
Figuras y tablas -
Analysis 7.1

Comparison 7 Prolapse repair and new urinary symptoms, Outcome 1 Number of women with de novo (new) stress urinary incontinence (subjective diagnosis).

Comparison 7 Prolapse repair and new urinary symptoms, Outcome 2 Number of women with de novo (new) stress urinary incontinence (objective diagnosis).
Figuras y tablas -
Analysis 7.2

Comparison 7 Prolapse repair and new urinary symptoms, Outcome 2 Number of women with de novo (new) stress urinary incontinence (objective diagnosis).

Comparison 7 Prolapse repair and new urinary symptoms, Outcome 3 Number of women with urgency, detrusor overactivity or overactive bladder.
Figuras y tablas -
Analysis 7.3

Comparison 7 Prolapse repair and new urinary symptoms, Outcome 3 Number of women with urgency, detrusor overactivity or overactive bladder.

Comparison 7 Prolapse repair and new urinary symptoms, Outcome 4 Number of women with de novo (new) urgency, detrusor overactivity or overactive bladder.
Figuras y tablas -
Analysis 7.4

Comparison 7 Prolapse repair and new urinary symptoms, Outcome 4 Number of women with de novo (new) urgency, detrusor overactivity or overactive bladder.

Comparison 7 Prolapse repair and new urinary symptoms, Outcome 5 Long term new voiding dysfunction.
Figuras y tablas -
Analysis 7.5

Comparison 7 Prolapse repair and new urinary symptoms, Outcome 5 Long term new voiding dysfunction.

Comparison 7 Prolapse repair and new urinary symptoms, Outcome 6 Number of women having further surgery for incontinence.
Figuras y tablas -
Analysis 7.6

Comparison 7 Prolapse repair and new urinary symptoms, Outcome 6 Number of women having further surgery for incontinence.

Comparison 8 Use of native tissue versus mesh or foreign material, Outcome 1 Number of women with anterior prolapse / cystocele (objective failure).
Figuras y tablas -
Analysis 8.1

Comparison 8 Use of native tissue versus mesh or foreign material, Outcome 1 Number of women with anterior prolapse / cystocele (objective failure).

Comparison 8 Use of native tissue versus mesh or foreign material, Outcome 2 Number of women with posterior prolapse / rectocele (objective failure).
Figuras y tablas -
Analysis 8.2

Comparison 8 Use of native tissue versus mesh or foreign material, Outcome 2 Number of women with posterior prolapse / rectocele (objective failure).

Comparison 8 Use of native tissue versus mesh or foreign material, Outcome 3 Number of women with postoperative complications.
Figuras y tablas -
Analysis 8.3

Comparison 8 Use of native tissue versus mesh or foreign material, Outcome 3 Number of women with postoperative complications.

Comparison 8 Use of native tissue versus mesh or foreign material, Outcome 4 Death.
Figuras y tablas -
Analysis 8.4

Comparison 8 Use of native tissue versus mesh or foreign material, Outcome 4 Death.

Comparison 1. Surgery for upper vaginal (vault/uterine) prolapse

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Number of women with prolapse symptoms (subjective failure) Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

1.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

2

169

Risk Ratio (M‐H, Fixed, 95% CI)

0.53 [0.25, 1.09]

1.2 abdominal sacrohysteropexy with Gore‐Tex vs vaginal hysterectomy, vaginal repair, uterosacral ligament plicati

1

82

Risk Ratio (M‐H, Fixed, 95% CI)

3.2 [1.29, 7.92]

2 Number of women with any prolapse (objective failure) Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

2.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy (failed)

1

88

Risk Ratio (M‐H, Fixed, 95% CI)

0.77 [0.39, 1.53]

2.2 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy (not improved)

1

118

Risk Ratio (M‐H, Fixed, 95% CI)

0.29 [0.09, 0.97]

2.3 posterior intravaginal slingplasty vs sacrospinous colpopexy

1

32

Risk Ratio (M‐H, Fixed, 95% CI)

0.8 [0.26, 2.45]

3 Number of women with recurrent vault prolapse (objective) Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

3.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

2

169

Risk Ratio (M‐H, Fixed, 95% CI)

0.23 [0.07, 0.77]

4 Number of women unsatisfied with surgery Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

4.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

89

Risk Ratio (M‐H, Fixed, 95% CI)

0.82 [0.32, 2.06]

5 Number of women with post‐operative stress urinary incontinence Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

5.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

2

155

Risk Ratio (M‐H, Fixed, 95% CI)

0.55 [0.32, 0.95]

6 Number of women with urgency, detrusor overactivity or overactive bladder Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

6.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

7 Number of women with de novo (new) urgency, detrusor overactivity or overactive bladder Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

7.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

8 Number of women with persistent voiding dysfunction Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

8.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

9 Number of women with new voiding dysfunction Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

9.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

10 Number of women with constipation Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

10.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

11 Number of women with faecal incontinence Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

11.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

11.2 posterior intravaginal slingplasty vs sacrospinous colpopexy

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

12 Number of women with obstructed defecation Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

12.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

13 Postoperative dyspareunia Show forest plot

4

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

13.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

3

106

Risk Ratio (M‐H, Fixed, 95% CI)

0.39 [0.18, 0.86]

13.2 posterior intravaginal slingplasty vs sacrospinous colpopexy

1

32

Risk Ratio (M‐H, Fixed, 95% CI)

0.33 [0.01, 7.62]

14 Women with de novo (new) postoperative dyspareunia Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

14.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

15 Blood loss (ml) Show forest plot

4

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

15.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

2

213

Mean Difference (IV, Fixed, 95% CI)

‐156.52 [‐212.71, ‐100.32]

15.2 abdominal sacrohysteropexy with Gore‐Tex vs vaginal hysterectomy, vaginal repair, uterosacral ligament plicati

1

82

Mean Difference (IV, Fixed, 95% CI)

‐4.0 [‐22.91, 14.91]

15.3 posterior intravaginal slingplasty vs sacrospinous colpopexy

1

32

Mean Difference (IV, Fixed, 95% CI)

‐50.00 [‐77.48, ‐26.52]

16 Postoperative decrease in Hb (gm/dl) Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

16.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

17 Operating time (minutes) Show forest plot

5

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

17.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

3

293

Mean Difference (IV, Fixed, 95% CI)

21.04 [12.15, 29.94]

17.2 abdominal sacrohysteropexy with Gore‐Tex vs vaginal hysterectomy, vaginal repair, uterosacral ligament plicati

1

82

Mean Difference (IV, Fixed, 95% CI)

‐10.0 [‐11.81, ‐8.19]

17.3 posterior intravaginal slingplasty vs sacrospinous colpopexy

1

32

Mean Difference (IV, Fixed, 95% CI)

‐14.0 [‐25.28, ‐2.72]

18 Length of stay in hospital (days) Show forest plot

4

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

18.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

3

293

Mean Difference (IV, Fixed, 95% CI)

0.14 [‐0.25, 0.53]

18.2 abdominal sacrohysteropexy with Gore‐Tex vs vaginal hysterectomy, vaginal repair, uterosacral ligament plicati

1

82

Mean Difference (IV, Fixed, 95% CI)

0.10 [‐0.01, 0.21]

19 Time to return to normal activity (days) Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

19.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

20 Cost (US dollars) Show forest plot

2

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

20.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

2

169

Mean Difference (IV, Fixed, 95% CI)

1333.95 [1027.24, 1640.65]

21 Women having further prolapse surgery Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

21.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

2

169

Risk Ratio (M‐H, Fixed, 95% CI)

0.46 [0.19, 1.11]

21.2 abdominal sacrohysteropexy with Gore‐Tex vs vaginal hysterectomy, vaginal repair, uterosacral ligament plicati

1

82

Risk Ratio (M‐H, Fixed, 95% CI)

9.0 [1.19, 67.85]

22 Women having further continence surgery Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

22.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

3

287

Risk Ratio (M‐H, Fixed, 95% CI)

0.60 [0.21, 1.73]

23 Women having further prolapse or continence surgery Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

23.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

2

169

Risk Ratio (M‐H, Fixed, 95% CI)

0.47 [0.23, 0.97]

24 Time to recurrence of prolapse (months) Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

24.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

25 Adverse events Show forest plot

5

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

25.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

3

287

Risk Ratio (M‐H, Fixed, 95% CI)

1.30 [0.63, 2.69]

25.2 abdominal sacrohysteropexy with Gore‐Tex vs vaginal hysterectomy, vaginal repair, uterosacral ligament plicati

1

82

Risk Ratio (M‐H, Fixed, 95% CI)

1.2 [0.40, 3.62]

25.3 posterior intravaginal slingplasty vs sacrospinous colpopexy

1

47

Risk Ratio (M‐H, Fixed, 95% CI)

1.28 [0.32, 5.10]

26 Number of women with recurrent rectocele (objective) Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

26.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

89

Risk Ratio (M‐H, Fixed, 95% CI)

2.49 [0.71, 8.79]

27 Number of women with recurrent cystocele (objective) Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

27.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

1

89

Risk Ratio (M‐H, Fixed, 95% CI)

0.47 [0.12, 1.75]

Figuras y tablas -
Comparison 1. Surgery for upper vaginal (vault/uterine) prolapse
Comparison 2. One method of anterior prolapse repair versus another surgical method

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Number of women with prolapse symptoms (subjective failure) Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

1.3 traditional anterior colporraphy vs abdominal Burch colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

1.4 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

1.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

2 Number of women with prolapse (objective failure) Show forest plot

4

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

2.3 traditional anterior colporraphy vs abdominal Burch colposuspension

1

68

Risk Ratio (M‐H, Fixed, 95% CI)

0.06 [0.01, 0.39]

2.4 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

2

138

Risk Ratio (M‐H, Fixed, 95% CI)

0.66 [0.34, 1.27]

2.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

0.88 [0.37, 2.05]

3 Number of women with anterior prolapse / cystocele (objective failure) Show forest plot

7

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

3.1 traditonal anterior colporrhaphy vs abdominal paravaginal repair

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

3.2 traditional anterior colporraphy vs ultralateral anterior colporraphy

1

57

Risk Ratio (M‐H, Fixed, 95% CI)

1.29 [0.84, 1.98]

3.3 traditional anterior colporraphy vs anterior colporraphy + mesh reinforcement

2

202

Risk Ratio (M‐H, Fixed, 95% CI)

1.48 [1.07, 2.04]

3.4 ultralateral anterior colporraphy vs anterior colporraphy + mesh reinforcement

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

0.94 [0.57, 1.54]

3.5 traditional anterior colporraphy vs abdominal Burch colposuspension

1

68

Risk Ratio (M‐H, Fixed, 95% CI)

0.09 [0.01, 0.64]

3.6 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

2

138

Risk Ratio (M‐H, Fixed, 95% CI)

0.55 [0.23, 1.29]

3.7 cystopexy vs cystopexy + pubourethral ligament plication

1

102

Risk Ratio (M‐H, Fixed, 95% CI)

0.96 [0.14, 6.57]

3.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

1.17 [0.46, 2.98]

4 Number of women with posterior prolapse / rectocele (objective failure) Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

4.1 traditional anterior colporraphy vs anterior colporraphy + mesh reinforcement

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

4.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

6 Number of women with pre‐operative stress incontinence not cured Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

6.3 traditional anterior colporraphy vs abdominal Burch colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

6.4 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

7 Number of women with de novo (new) stress urinary incontinence Show forest plot

4

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

7.3 cystopexy vs cystopexy + pubourethral ligament plication

1

102

Risk Ratio (M‐H, Fixed, 95% CI)

0.96 [0.25, 3.64]

7.5 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

2

102

Risk Ratio (M‐H, Fixed, 95% CI)

2.62 [0.63, 10.91]

7.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

9.0 [1.23, 65.85]

8 Number of women with urgency, detrusor overactivity or overactive bladder Show forest plot

5

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

8.3 traditional anterior colporraphy vs abdominal Burch colposuspension

1

68

Risk Ratio (M‐H, Fixed, 95% CI)

1.06 [0.07, 16.27]

8.4 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

2

138

Risk Ratio (M‐H, Fixed, 95% CI)

0.96 [0.20, 4.49]

8.5 cystopexy vs cystopexy + pubourethral ligament plication

1

102

Risk Ratio (M‐H, Fixed, 95% CI)

0.96 [0.06, 14.96]

8.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

0.33 [0.04, 2.99]

9 Number of women with dyspareunia Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

9.3 traditional anterior colporraphy vs abdominal Burch colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

9.4 cystopexy vs cystopexy + pubourethral ligament plication

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

10 Operating time (minutes) Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

10.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

11 Blood loss (ml) Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

11.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

12 Haemoglobin change Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

12.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

13 Time to return to spontaneous voiding (days) Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

13.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

14 Number of women with postoperative complications Show forest plot

6

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

14.2 traditional anterior colporraphy vs ultralateral anterior colporraphy

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

14.3 traditional anterior colporraphy vs anterior colporraphy + mesh reinforcement

2

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

14.4 ultralateral anterior colporraphy vs anterior colporraphy + mesh reinforcement

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

14.5 traditional anterior colporraphy vs abdominal Burch colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

14.6 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

14.7 cystopexy vs cystopexy + pubourethral ligament plication

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

14.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

15 Length of stay in hospital (days) Show forest plot

3

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

15.3 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

15.4 cystopexy vs cystopexy + pubourethral ligament plication

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

15.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

18 Number of women having further prolapse surgery Show forest plot

4

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

18.3 traditional anterior colporraphy vs abdominal Burch colposuspension

1

68

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

18.4 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

2

138

Risk Ratio (M‐H, Fixed, 95% CI)

0.41 [0.06, 2.71]

18.5 cystopexy vs cystopexy + pubourethral ligament plication

1

102

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

19 Number of women having further surgery for incontinence Show forest plot

4

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

19.3 traditional anterior colporraphy vs abdominal Burch colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

19.4 cystopexy vs cystopexy + pubourethral ligament plication

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

19.5 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

19.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

20 Persistent voiding dysfunction Show forest plot

5

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

20.3 traditional anterior colporraphy vs abdominal Burch colposuspension

1

68

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

20.4 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

2

138

Risk Ratio (M‐H, Fixed, 95% CI)

1.05 [0.49, 2.26]

20.5 cystopexy vs cystopexy + pubourethral ligament plication

1

102

Risk Ratio (M‐H, Fixed, 95% CI)

0.09 [0.00, 1.54]

20.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

0.33 [0.04, 2.99]

21 Number of women with worse bowel function Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

21.1 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

23 Death Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

23.1 traditional anterior colporraphy vs ultralateral anterior colporraphy

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

23.2 traditional anterior colporraphy vs anterior colporraphy + mesh reinforcement

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

23.3 ultralateral anterior colporraphy vs anterior colporraphy + mesh reinforcement

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

Figuras y tablas -
Comparison 2. One method of anterior prolapse repair versus another surgical method
Comparison 3. One method of posterior prolapse repair versus another surgical method

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Number of women with prolapse symptoms (subjective failure) Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

1.1 posterior vaginal colporrhaphy vs transanal repair

2

87

Risk Ratio (M‐H, Fixed, 95% CI)

0.36 [0.13, 1.00]

2 Number of women with prolapse (objective failure) Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

2.1 posterior vaginal colporrhaphy vs transanal repair (rectocele)

2

87

Risk Ratio (M‐H, Fixed, 95% CI)

0.32 [0.07, 1.34]

2.2 posterior vaginal colporrhaphy vs transanal repair (enterocele)

2

87

Risk Ratio (M‐H, Fixed, 95% CI)

0.23 [0.07, 0.83]

2.3 posterior vaginal colporrhaphy vs transanal repair (rectocele or enterocele))

2

87

Risk Ratio (M‐H, Fixed, 95% CI)

0.24 [0.09, 0.64]

2.4 posterior vaginal colporraphy vs posterior colporraphy with mesh reinforcement for rectocele

1

132

Risk Ratio (M‐H, Fixed, 95% CI)

1.13 [0.40, 3.19]

4 Number of women with faecal incontinence after operation Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

4.1 posterior vaginal colporrhaphy vs transanal repair

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

5 Number of women with anal incontinence to flatus after operation Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

5.1 posterior vaginal colporrhaphy vs transanal repair

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

6 Number of women with obstructed defecation / constipation after surgery Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

6.1 posterior vaginal colporrhaphy vs transanal repair

2

65

Risk Ratio (M‐H, Fixed, 95% CI)

0.73 [0.37, 1.42]

7 Number of women with sexual function not improved after operation Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

7.1 posterior vaginal colporrhaphy vs transanal repair

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

8 Number of women with dyspareunia Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

8.1 posterior vaginal colporrhaphy vs transanal repair

2

80

Risk Ratio (M‐H, Fixed, 95% CI)

3.13 [0.87, 11.23]

9 Blood loss (ml) Show forest plot

2

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

9.1 posterior vaginal colporrhaphy vs transanal repair

2

87

Mean Difference (IV, Fixed, 95% CI)

79.38 [39.69, 119.08]

10 Difference in haemoglobin Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

10.1 posterior vaginal colporrhaphy vs transanal repair

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

11 Operating time (minutes) Show forest plot

2

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

11.1 posterior vaginal colporrhaphy vs transanal repair

2

87

Mean Difference (IV, Fixed, 95% CI)

‐3.64 [‐7.43, 0.15]

12 Postoperative narcotic (morphine) use Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

12.1 posterior vaginal colporrhaphy vs transanal repair

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

13 Number of women with postoperative complications Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

13.1 posterior vaginal colporrhaphy vs transanal repair

2

87

Risk Ratio (M‐H, Fixed, 95% CI)

3.56 [0.80, 15.74]

14 Persistent postoperative pain Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

14.1 posterior vaginal colporrhaphy vs transanal repair

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

15 Length of stay in hospital (days) Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

15.1 posterior vaginal colporrhaphy vs transanal repair

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

Figuras y tablas -
Comparison 3. One method of posterior prolapse repair versus another surgical method
Comparison 7. Prolapse repair and new urinary symptoms

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Number of women with de novo (new) stress urinary incontinence (subjective diagnosis) Show forest plot

5

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

1.1 cystopexy vs cystopexy + pubourethral ligament plication

1

102

Risk Ratio (M‐H, Fixed, 95% CI)

0.96 [0.25, 3.64]

1.2 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

2

102

Risk Ratio (M‐H, Fixed, 95% CI)

2.62 [0.63, 10.91]

1.4 abdominal colpopexy vs vaginal colpopexy

1

46

Risk Ratio (M‐H, Fixed, 95% CI)

0.27 [0.06, 1.15]

1.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

9.0 [1.23, 65.85]

2 Number of women with de novo (new) stress urinary incontinence (objective diagnosis) Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

2.2 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

2.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

3 Number of women with urgency, detrusor overactivity or overactive bladder Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

3.6 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

4 Number of women with de novo (new) urgency, detrusor overactivity or overactive bladder Show forest plot

4

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

4.1 abdominal colpopexy vs vaginal colpopexy

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

4.2 cystopexy vs cystopexy + pubourethral ligament plication

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

4.3 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

4.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

5 Long term new voiding dysfunction Show forest plot

5

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

5.1 abdominal colpopexy vs vaginal colpopexy

1

75

Risk Ratio (M‐H, Fixed, 95% CI)

1.03 [0.07, 15.82]

5.4 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

2

138

Risk Ratio (M‐H, Fixed, 95% CI)

1.05 [0.49, 2.26]

5.5 cystopexy vs cystopexy + pubourethral ligament plication

1

102

Risk Ratio (M‐H, Fixed, 95% CI)

0.09 [0.00, 1.54]

5.8 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

0.33 [0.04, 2.99]

6 Number of women having further surgery for incontinence Show forest plot

5

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

6.1 abdominal sacral colpopexy vs vaginal sacrospinous colpopexy

2

207

Risk Ratio (M‐H, Fixed, 95% CI)

1.05 [0.28, 3.95]

6.2 cystopexy vs cystopexy + pubourethral ligament plication

1

102

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

6.3 prolapse repair + urethrovesical plication vs prolapse repair + needle colposuspension

1

73

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

6.4 prolapse repair + urethrovesical endopelvic fascia repair vs prolapse repair + TVT

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

7.0 [0.38, 128.87]

Figuras y tablas -
Comparison 7. Prolapse repair and new urinary symptoms
Comparison 8. Use of native tissue versus mesh or foreign material

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Number of women with anterior prolapse / cystocele (objective failure) Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

1.1 traditional or ultralateral anterior colporraphy vs anterior colporraphy + mesh reinforcement

2

226

Risk Ratio (M‐H, Fixed, 95% CI)

1.39 [1.02, 1.90]

2 Number of women with posterior prolapse / rectocele (objective failure) Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

2.1 traditional anterior colporraphy vs anterior colporraphy + mesh reinforcement

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

3 Number of women with postoperative complications Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

3.3 traditional or ultralateral anterior colporraphy vs anterior colporraphy + mesh reinforcement

2

252

Risk Ratio (M‐H, Fixed, 95% CI)

0.95 [0.09, 10.08]

4 Death Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

4.1 traditional or ultralateral anterior colporraphy vs anterior colporraphy + mesh reinforcement

1

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

Figuras y tablas -
Comparison 8. Use of native tissue versus mesh or foreign material