Anti‐inflammatory treatment for carditis in acute rheumatic fever

Scolaris Content Display Scolaris Content Display

Ir a:

Figure 1

Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.

Figure 2

Risk of bias summary: review authors' judgements about each risk of bias item for each included study.

Analysis 1.1

Comparison 1 Corticosteroids versus aspirin, Outcome 1 Cardiac disease after 1 year.

Analysis 1.2

Comparison 1 Corticosteroids versus aspirin, Outcome 2 Outcome of severe cardiac disease after 1 year.

Analysis 2.1

Comparison 2 Individual corticosteroids versus aspirin, Outcome 1 Cardiac disease after 1 year.

Comparison 1. Corticosteroids versus aspirin

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Cardiac disease after 1 year Show forest plot	6	907	Risk Ratio (M‐H, Random, 95% CI)	0.87 [0.66, 1.15]

2 Outcome of severe cardiac disease after 1 year Show forest plot	3	119	Risk Ratio (M‐H, Random, 95% CI)	0.94 [0.32, 2.70]

Comparison 1. Corticosteroids versus aspirin

Comparison 2. Individual corticosteroids versus aspirin

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Cardiac disease after 1 year Show forest plot	3	276	Risk Ratio (M‐H, Random, 95% CI)	0.86 [0.42, 1.76]

1.1 Hydrocortisone versus aspirin	1	64	Risk Ratio (M‐H, Random, 95% CI)	0.43 [0.19, 0.97]
1.2 Prednisone versus aspirin	2	212	Risk Ratio (M‐H, Random, 95% CI)	1.13 [0.52, 2.45]

Comparison 2. Individual corticosteroids versus aspirin