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Cochrane Database of Systematic Reviews

Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility

Esta versión no es la más reciente

Información

DOI:
https://doi.org/10.1002/14651858.CD003053.pub5Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 16 mayo 2012see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Ginecología y fertilidad

Copyright:
  1. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Contraer

Autores

  • Thomas Tang

    Obstetrics and Gynaecology, Bradford Teaching Hospitals NHS Trust, Bradford, UK

  • Jonathan M Lord

    Royal Cornwall Hospital, Peninsula Medical School, Truro, UK

  • Robert J Norman

    Obstetrics & Gynaecology, Robinson Institute, University of Adelaide, Adelaide, Australia

  • Ephia Yasmin

    Reproductive Medicine Unit, Clarendon Wing, The General Infirmary of Leeds, Leeds, UK

  • Adam H Balen

    Correspondencia a: Reproductive Medicine and Surgery, United Leeds Teaching Hospitals, Leeds, UK

    [email protected]

Contributions of authors

JML ‐ primary literature search, initial assessment of trials and quality analysis, data collection, analysis, initial draft of full review (2003 version)

IF ‐ developing protocol, checking literature search, secondary assessment of trials and quality analysis (blinded), reviewing data collection and analysis, revising first draft of full review (2003 version)

RN ‐ developing protocol, final arbiter to resolve differences in quality assessment between other reviewers, finalising final review, content and Cochrane expert (2003 version)

TT ‐ literature search, assessment of trials, data collection and analysis in the update period (January 2003 to November 2010). Preparation of the revised review (2008 and 2010 version).

EY ‐ checking literature search and secondary assessment of trials (2008 and 2010 version)

AB ‐ secondary assessment of trials and quality analysis. Revising and finalizing the final revised review (2008 and 2010 version)

Sources of support

Internal sources

  • Peninsula Medical School, UK.

  • University of Adelaide, Australia.

  • Department of Reproductive Medicine, Leeds, UK.

External sources

  • No sources of support supplied

Declarations of interest

None declared

Acknowledgements

We would like to thank the corresponding authors of the following trials who took time to respond to our requests for further data, some of whom took the trouble to perform repeat analyses for us:

Chou 2003; Fleming 2002; Glintborg 2005; Hoeger 2004; Hwu 2005; Jakubowicz 2001; Ladson 2011; Legro 2007; Lord 2006; Malkawi 2002; Moghetti 2000; Nestler 1997; Nestler 1999; Ng 2001; Rautio 2006; Sturrock 2002; Trolle 2007; Vandermolen 2001; Yarali 2002.

We would also like to thank the Cochrane Menstrual Disorders and Subfertility Review Group in Auckland, and in particular their Managing Editor (to 2011) Jane Clarke, for all their help and support. We are also grateful to Rafael Perera of the UK Cochrane Centre for statistical advice.

Version history

Published

Title

Stage

Authors

Version

2017 Nov 28

Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility

Review

Lara C Morley, Thomas Tang, Ephia Yasmin, Robert J Norman, Adam H Balen

https://doi.org/10.1002/14651858.CD003053.pub6

2012 May 16

Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility

Review

Thomas Tang, Jonathan M Lord, Robert J Norman, Ephia Yasmin, Adam H Balen

https://doi.org/10.1002/14651858.CD003053.pub5

2010 Jan 20

Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility

Review

Thomas Tang, Jonathan M Lord, Robert J Norman, Ephia Yasmin, Adam H Balen

https://doi.org/10.1002/14651858.CD003053.pub4

2009 Oct 07

Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility

Review

Thomas Tang, Jonathan M Lord, Robert J Norman, Ephia Yasmin, Adam H Balen

https://doi.org/10.1002/14651858.CD003053.pub3

2009 Jul 08

Insulin‐sensitising drugs for polycystic ovary syndrome

Review

Thomas Tang, Jonathan M Lord, Robert J Norman, Ephia Yasmin, Adam H Balen

https://doi.org/10.1002/14651858.CD003053.pub2

2003 Apr 22

Insulin‐sensitising drugs (metformin, troglitazone, rosiglitazone, pioglitazone, D‐chiro‐inositol) for polycystic ovary syndrome

Review

Thomas Tang, Robert J Norman, Adam H Balen, Jonathan M Lord

https://doi.org/10.1002/14651858.CD003053

Differences between protocol and review

In the updated review, the title was changed from 'Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for polycystic ovary syndrome' to 'Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility'.

The outcome measures were restructured. One new comparison was added (metformin versus clomiphene).

Studies using troglitazone were excluded.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.