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Cochrane Database of Systematic Reviews

Dosis única de paracetamol oral (acetaminofeno), con y sin codeína, para el dolor postoperatorio en adultos

Información

DOI:
https://doi.org/10.1002/14651858.CD001547.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 21 enero 2009see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Dolor y cuidados paliativos

Copyright:
  1. Copyright © 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Contraer

Autores

  • Laurence Toms

    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford, UK

  • Sheena Derry

    Correspondencia a: Oxford, UK

    [email protected]

  • R Andrew Moore

    Plymouth, UK

  • Henry J McQuay

    Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics), University of Oxford, Oxford, UK

Contributions of authors

LT and SD identified studies for inclusion in this update and carried out data extraction, analysis and writing. RAM was involved with planning, analysis and writing, and acted as arbitrator. HJM was involved in planning and writing.

Sources of support

Internal sources

  • Oxford Pain Research Funds, UK.

External sources

  • NHS Cochrane Collaboration Programme Grant Scheme, UK.

    Funding

  • European Union Biomed 2 Grant no. BMH4 CT95 0172, UK.

Declarations of interest

LT has no interests to declare. RAM and HJM have consulted for various pharmaceutical companies. RAM and HJM and have received lecture fees from pharmaceutical companies related to analgesics and other healthcare interventions. SD, RAM and HJM have received research support from charities, government and industry sources at various times: no support other than the declared financial support was received for this work.

Acknowledgements

Sally Collins, Dawn Carroll and Jayne Rees were authors on the original review; Martin Tramèr, Marie Bisercic and Anna Oldman translated reports, and Clare Abbott helped with obtaining a mountain of papers. Sources of support for the original review were: Anglia and Oxford RHA, UK, NHS Research and Development Health Technology Evaluation Programmes, UK, and European Union Biomed 2 Grant no. BMH4 CT95 0172, UK.

Version history

Published

Title

Stage

Authors

Version

2009 Jan 21

Single dose oral paracetamol (acetaminophen) with codeine for postoperative pain in adults

Review

Laurence Toms, Sheena Derry, R Andrew Moore, Henry J McQuay

https://doi.org/10.1002/14651858.CD001547.pub2

1998 Oct 26

Single dose paracetamol (acetaminophen), with and without codeine, for postoperative pain

Review

A Moore, S Collins, D Carroll, H McQuay, J Edwards

https://doi.org/10.1002/14651858.CD001547

Notes

2011: This review is an update of a previous review of single dose paracetamol and codeine in postoperative pain. Originally paracetamol plus codeine was part of a larger review that included paracetamol alone, published in 1998. The original review was split into two components and both have been updated in 2008.

2016: A restricted search in June 2016 only identified one relevant study (Gatoulis 2012). However, we judged that this study was unlikely to change the conclusions. Therefore, this review has now been stabilised for five years following discussion with the authors and editors. If appropriate, we will update the review before this date if new evidence likely to change the conclusions is published, or if standards change substantially which necessitate major revisions.

Gatoulis SC, Voelker M, Fisher M: Assessment of the efficacy and safety profiles of aspirin and acetaminophen with codeine: results from 2 randomized, controlled trials in individuals with tension‐type headache and postoperative dental pain; Clinical therapeutics 2012; 34(1):138‐48.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.