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Comparison 1 colloid vs crystalloid (add‐on colloid), Outcome 1 deaths.
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Analysis 1.1

Comparison 1 colloid vs crystalloid (add‐on colloid), Outcome 1 deaths.

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Comparison 2 colloid and hypertonic crystalloid vs isotonic crystalloid, Outcome 1 deaths.
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Analysis 2.1

Comparison 2 colloid and hypertonic crystalloid vs isotonic crystalloid, Outcome 1 deaths.

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Comparison 3 colloid vs hypertonic crystalloid, Outcome 1 deaths.
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Analysis 3.1

Comparison 3 colloid vs hypertonic crystalloid, Outcome 1 deaths.

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Comparison 1. colloid vs crystalloid (add‐on colloid)

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 deaths Show forest plot

37

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

1.1 albumin or PPF

20

7576

Risk Ratio (M‐H, Fixed, 95% CI)

1.02 [0.93, 1.11]

1.2 hydroxyethylstarch

10

374

Risk Ratio (M‐H, Fixed, 95% CI)

1.16 [0.68, 1.96]

1.3 modified gelatin

7

346

Risk Ratio (M‐H, Fixed, 95% CI)

0.54 [0.16, 1.85]

1.4 dextran

9

834

Risk Ratio (M‐H, Fixed, 95% CI)

1.24 [0.94, 1.65]
Figuras y tablas -
Comparison 1. colloid vs crystalloid (add‐on colloid)
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Comparison 2. colloid and hypertonic crystalloid vs isotonic crystalloid

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 deaths Show forest plot

9

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

1.1 albumin or PPF

1

14

Risk Ratio (M‐H, Fixed, 95% CI)

0.5 [0.06, 4.33]

1.2 hydroxyethylstarch

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

1.3 modified gelatin

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

1.4 dextran

8

1283

Risk Ratio (M‐H, Fixed, 95% CI)

0.88 [0.74, 1.05]
Figuras y tablas -
Comparison 2. colloid and hypertonic crystalloid vs isotonic crystalloid
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Comparison 3. colloid vs hypertonic crystalloid

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 deaths Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

1.1 albumin or PPF

1

38

Risk Ratio (M‐H, Fixed, 95% CI)

7.0 [0.39, 126.92]

1.2 hydroxyethylstarch

1

16

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

1.3 modified gelatin

1

20

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

1.4 dextran

0

0

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]
Figuras y tablas -
Comparison 3. colloid vs hypertonic crystalloid
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