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Cochrane Database of Systematic Reviews

Barbitúricos para la lesión cerebral traumática aguda

Información

DOI:
https://doi.org/10.1002/14651858.CD000033.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 12 diciembre 2012see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Lesiones

Copyright:
  1. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Autores

  • Ian Roberts

    Correspondencia a: Cochrane Injuries Group, London School of Hygiene & Tropical Medicine, London, UK

    [email protected]

  • Emma Sydenham

    Cochrane Injuries Group, London School of Hygiene & Tropical Medicine, London, UK

Contributions of authors

IR wrote all versions of the review through to May 2009. Data extraction was checked by the Cochrane Injuries Group editorial team prior to publication.

ES and IR updated the review in July 2009. Both authors approved the final version of the update.

For the 2012 update both ES and IR screened the search results. ES re‐screened all previous search results (248 citations). ES updated the 'Risk of bias' tables, checked the data (they were correct) and edited the manuscript according to the Methodological Expectations of Cochrane Intervention Reviews guidelines. IR and ES agreed on the final version of the manuscript.

Sources of support

Internal sources

  • No sources of support supplied

External sources

  • NHS Research & Development Programme: Maternal and Child Health, UK.

    1997 version

Declarations of interest

None known.

Acknowledgements

The Cochrane Injuries Group's Trials Search Co‐ordinators for developing the search strategy and running the searches.

The trial authors for replying to our requests for additional information (in some cases over 30 years following completion of the trial).

Version history

Published

Title

Stage

Authors

Version

2012 Dec 12

Barbiturates for acute traumatic brain injury

Review

Ian Roberts, Emma Sydenham

https://doi.org/10.1002/14651858.CD000033.pub2

1999 Jul 26

Barbiturates for acute traumatic brain injury

Review

Ian Roberts, Emma Sydenham

https://doi.org/10.1002/14651858.CD000033

Differences between protocol and review

There was no protocol for the original version of this review, which was published in 1997. According to IR, the review was conducted according to the methods described in version 3 of the Cochrane Collaboration Handbook that was published in 1996.

The original review used the scale developed by Schultz 1995 to assess allocation concealment only. As the methods of The Cochrane Collaboration have been updated, the review is now reported according to MECIR 2012 guidelines and the 'Risk of bias' tool has been used instead.

In the first version of the review "The major outcome data sought were numbers of deaths, and numbers of people disabled at the end of the study period. Disability was assessed using the Glasgow Outcome Scale." We have selected death at final follow‐up as the primary outcome for this and all future updates.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.