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Antiseptics for burns
Gill Norman, Janice Christie, Zhenmi Liu, Maggie J Westby, Jayne M Jefferies, Thomas Hudson, Jacky Edwards, Devi Prasad Mohapatra, Ibrahim A Hassan, Jo C Dumville | 12 July 2017

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Topics

Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.
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Figure 1

Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.

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Methodological quality summary: review authors' judgements about each methodological quality item for each included study.
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Figure 2

Methodological quality summary: review authors' judgements about each methodological quality item for each included study.

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Comparison 1 Drape versus no drape, Outcome 1 Wound infection.
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Analysis 1.1

Comparison 1 Drape versus no drape, Outcome 1 Wound infection.

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Comparison 1 Drape versus no drape, Outcome 2 Length of stay.
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Analysis 1.2

Comparison 1 Drape versus no drape, Outcome 2 Length of stay.

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Comparison 2 One‐minute alcohol scrub with iodophor‐drape versus five‐minute iodophor scrub without drape, Outcome 1 Wound infection.
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Analysis 2.1

Comparison 2 One‐minute alcohol scrub with iodophor‐drape versus five‐minute iodophor scrub without drape, Outcome 1 Wound infection.

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Comparison 2 One‐minute alcohol scrub with iodophor‐drape versus five‐minute iodophor scrub without drape, Outcome 2 Endomyometritis.
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Analysis 2.2

Comparison 2 One‐minute alcohol scrub with iodophor‐drape versus five‐minute iodophor scrub without drape, Outcome 2 Endomyometritis.

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Comparison 2 One‐minute alcohol scrub with iodophor‐drape versus five‐minute iodophor scrub without drape, Outcome 3 Reduction of skin bacteria colony counts.
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Analysis 2.3

Comparison 2 One‐minute alcohol scrub with iodophor‐drape versus five‐minute iodophor scrub without drape, Outcome 3 Reduction of skin bacteria colony counts.

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Comparison 3 Parachlorometaxylenol with iodine versus iodine alone, Outcome 1 Wound infection.
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Analysis 3.1

Comparison 3 Parachlorometaxylenol with iodine versus iodine alone, Outcome 1 Wound infection.

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Comparison 3 Parachlorometaxylenol with iodine versus iodine alone, Outcome 2 Endometritis.
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Analysis 3.2

Comparison 3 Parachlorometaxylenol with iodine versus iodine alone, Outcome 2 Endometritis.

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Comparison 1. Drape versus no drape

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Wound infection Show forest plot

2

1294

Risk Ratio (M‐H, Fixed, 95% CI)

1.29 [0.97, 1.71]

1.1 Iodine

1

691

Risk Ratio (M‐H, Fixed, 95% CI)

1.42 [0.98, 2.04]

1.2 Chlorhexidine

1

603

Risk Ratio (M‐H, Fixed, 95% CI)

1.11 [0.70, 1.76]

2 Length of stay Show forest plot

1

603

Mean Difference (IV, Fixed, 95% CI)

0.10 [‐0.27, 0.46]
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Comparison 1. Drape versus no drape
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Comparison 2. One‐minute alcohol scrub with iodophor‐drape versus five‐minute iodophor scrub without drape

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Wound infection Show forest plot

1

79

Risk Ratio (M‐H, Fixed, 95% CI)

0.0 [0.0, 0.0]

2 Endomyometritis Show forest plot

1

79

Risk Ratio (M‐H, Fixed, 95% CI)

1.62 [0.29, 9.16]

3 Reduction of skin bacteria colony counts Show forest plot

1

79

Mean Difference (IV, Fixed, 95% CI)

0.07 [‐0.34, 0.48]
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Comparison 2. One‐minute alcohol scrub with iodophor‐drape versus five‐minute iodophor scrub without drape
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Comparison 3. Parachlorometaxylenol with iodine versus iodine alone

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Wound infection Show forest plot

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

0.33 [0.04, 2.99]

2 Endometritis Show forest plot

1

50

Risk Ratio (M‐H, Fixed, 95% CI)

0.88 [0.56, 1.38]
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Comparison 3. Parachlorometaxylenol with iodine versus iodine alone
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