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Comparison 1 House dust mite reduction versus control, Outcome 1 Numbers improved.
Figures and Tables -
Analysis 1.1

Comparison 1 House dust mite reduction versus control, Outcome 1 Numbers improved.

Comparison 1 House dust mite reduction versus control, Outcome 2 Asthma symptoms score.
Figures and Tables -
Analysis 1.2

Comparison 1 House dust mite reduction versus control, Outcome 2 Asthma symptoms score.

Comparison 1 House dust mite reduction versus control, Outcome 3 Medication usage.
Figures and Tables -
Analysis 1.3

Comparison 1 House dust mite reduction versus control, Outcome 3 Medication usage.

Comparison 1 House dust mite reduction versus control, Outcome 4 FEV1 (Forced expiratory volume in one second).
Figures and Tables -
Analysis 1.4

Comparison 1 House dust mite reduction versus control, Outcome 4 FEV1 (Forced expiratory volume in one second).

Comparison 1 House dust mite reduction versus control, Outcome 5 PEFR morning (Peak Expiratory Flow Rate).
Figures and Tables -
Analysis 1.5

Comparison 1 House dust mite reduction versus control, Outcome 5 PEFR morning (Peak Expiratory Flow Rate).

Comparison 1 House dust mite reduction versus control, Outcome 6 PEFR evening (Peak Expiratory Flow Rate).
Figures and Tables -
Analysis 1.6

Comparison 1 House dust mite reduction versus control, Outcome 6 PEFR evening (Peak Expiratory Flow Rate).

Comparison 1 House dust mite reduction versus control, Outcome 7 PC20 (Provocative concentration for 20% fall in FEV1).
Figures and Tables -
Analysis 1.7

Comparison 1 House dust mite reduction versus control, Outcome 7 PC20 (Provocative concentration for 20% fall in FEV1).

Comparison 1. House dust mite reduction versus control

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Numbers improved Show forest plot

7

338

Risk Ratio (M‐H, Fixed, 95% CI)

1.01 [0.80, 1.27]

1.1 Chemical methods

3

138

Risk Ratio (M‐H, Fixed, 95% CI)

0.94 [0.72, 1.24]

1.2 Physical methods ‐ parallel group studies

1

53

Risk Ratio (M‐H, Fixed, 95% CI)

1.11 [0.70, 1.74]

1.3 Physical methods ‐ crossover studies

2

98

Risk Ratio (M‐H, Fixed, 95% CI)

1.2 [0.57, 2.54]

1.4 Combination methods

1

49

Risk Ratio (M‐H, Fixed, 95% CI)

0.85 [0.21, 3.40]

2 Asthma symptoms score Show forest plot

16

1216

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.03 [‐0.14, 0.08]

2.1 Chemical methods

4

125

Std. Mean Difference (IV, Fixed, 95% CI)

0.39 [0.04, 0.75]

2.2 Physical methods ‐ parallel group studies

7

829

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.06 [‐0.20, 0.07]

2.3 Physical methods ‐ crossover studies

3

70

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.48 [‐0.97, 0.01]

2.4 Combination methods

2

192

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.01 [‐0.29, 0.28]

3 Medication usage Show forest plot

8

859

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.05 [‐0.18, 0.09]

3.1 Chemical methods

1

23

Std. Mean Difference (IV, Fixed, 95% CI)

0.89 [0.02, 1.75]

3.2 Physical methods ‐ parallel group studies

4

764

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.06 [‐0.20, 0.08]

3.3 Physical methods ‐ crossover studies

3

72

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.17 [‐0.64, 0.29]

4 FEV1 (Forced expiratory volume in one second) Show forest plot

13

528

Std. Mean Difference (IV, Fixed, 95% CI)

0.11 [‐0.06, 0.29]

4.1 Chemical methods

4

125

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.05 [‐0.41, 0.30]

4.2 Physical methods ‐ parallel group studies

3

102

Std. Mean Difference (IV, Fixed, 95% CI)

0.34 [‐0.07, 0.75]

4.3 Physical methods ‐ crossover studies

2

42

Std. Mean Difference (IV, Fixed, 95% CI)

0.07 [‐0.53, 0.68]

4.4 Combination methods

4

259

Std. Mean Difference (IV, Fixed, 95% CI)

0.12 [‐0.12, 0.36]

5 PEFR morning (Peak Expiratory Flow Rate) Show forest plot

19

1339

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.02 [‐0.13, 0.08]

5.1 Chemical methods

4

125

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.21 [‐0.56, 0.15]

5.2 Physical methods ‐ parallel group studies

7

836

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.04 [‐0.18, 0.10]

5.3 Physical methods ‐ crossover studies

5

154

Std. Mean Difference (IV, Fixed, 95% CI)

0.06 [‐0.26, 0.37]

5.4 Combination methods

3

224

Std. Mean Difference (IV, Fixed, 95% CI)

0.09 [‐0.18, 0.35]

6 PEFR evening (Peak Expiratory Flow Rate) Show forest plot

9

233

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.10 [‐0.36, 0.16]

6.1 Chemical methods

2

53

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.49 [‐1.05, 0.07]

6.2 Physical methods ‐ parallel group studies

2

72

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.06 [‐0.52, 0.40]

6.3 Physical methods ‐ crossover studies

4

90

Std. Mean Difference (IV, Fixed, 95% CI)

0.06 [‐0.35, 0.47]

6.4 Combination methods

1

18

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.03 [‐0.96, 0.89]

7 PC20 (Provocative concentration for 20% fall in FEV1) Show forest plot

12

470

Std. Mean Difference (IV, Fixed, 95% CI)

0.03 [‐0.16, 0.21]

7.1 Chemical methods

5

150

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.11 [‐0.43, 0.21]

7.2 Physical methods, parallel group studies

3

100

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.01 [‐0.41, 0.39]

7.3 Physical methods ‐ crossover studies

1

18

Std. Mean Difference (IV, Fixed, 95% CI)

‐0.12 [‐1.05, 0.80]

7.4 Combination methods

4

202

Std. Mean Difference (IV, Fixed, 95% CI)

0.16 [‐0.12, 0.44]

Figures and Tables -
Comparison 1. House dust mite reduction versus control