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Funnel plot of comparison: 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, outcome: 1.6 No cure.
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Figure 1

Funnel plot of comparison: 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, outcome: 1.6 No cure.

Comparison 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, Outcome 1 No cure.
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Analysis 1.1

Comparison 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, Outcome 1 No cure.

Comparison 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, Outcome 2 Preterm delivery.
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Analysis 1.2

Comparison 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, Outcome 2 Preterm delivery.

Comparison 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, Outcome 3 Preterm delivery or low birthweight.
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Analysis 1.3

Comparison 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, Outcome 3 Preterm delivery or low birthweight.

Comparison 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, Outcome 4 Pyelonephritis.
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Analysis 1.4

Comparison 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, Outcome 4 Pyelonephritis.

Comparison 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, Outcome 5 Side effects.
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Analysis 1.5

Comparison 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, Outcome 5 Side effects.

Comparison 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, Outcome 6 Recurrent asymptomatic bacteriuria.
Figures and Tables -
Analysis 1.6

Comparison 1 Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria, Outcome 6 Recurrent asymptomatic bacteriuria.

Comparison 1. Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 No cure Show forest plot

13

1502

Risk Ratio (M‐H, Random, 95% CI)

1.33 [0.88, 2.01]

1.1 Same antimicrobial agent

10

1286

Risk Ratio (M‐H, Random, 95% CI)

1.43 [0.87, 2.34]

1.2 Different antimicrobial agents

3

216

Risk Ratio (M‐H, Random, 95% CI)

0.98 [0.49, 1.95]

2 Preterm delivery Show forest plot

3

804

Risk Ratio (M‐H, Random, 95% CI)

1.09 [0.52, 2.26]

2.1 Same antimicrobial agent

3

804

Risk Ratio (M‐H, Random, 95% CI)

1.09 [0.52, 2.26]

3 Preterm delivery or low birthweight Show forest plot

1

714

Risk Difference (M‐H, Random, 95% CI)

0.05 [0.01, 0.10]

3.1 Same antimicrobial agent

1

714

Risk Difference (M‐H, Random, 95% CI)

0.05 [0.01, 0.10]

4 Pyelonephritis Show forest plot

2

102

Risk Ratio (M‐H, Random, 95% CI)

2.97 [0.51, 17.28]

4.1 Same antimicrobial agent

2

102

Risk Ratio (M‐H, Random, 95% CI)

2.97 [0.51, 17.28]

5 Side effects Show forest plot

12

1460

Risk Ratio (M‐H, Fixed, 95% CI)

0.70 [0.56, 0.88]

5.1 Same antimicrobial agent

9

1244

Risk Ratio (M‐H, Fixed, 95% CI)

0.77 [0.61, 0.97]

5.2 Different antimicrobial agents

3

216

Risk Ratio (M‐H, Fixed, 95% CI)

0.16 [0.04, 0.58]

6 Recurrent asymptomatic bacteriuria Show forest plot

8

445

Risk Ratio (M‐H, Random, 95% CI)

1.09 [0.75, 1.60]

6.1 Same antimicrobial agent

6

313

Risk Ratio (M‐H, Random, 95% CI)

1.08 [0.74, 1.60]

6.2 Different antimicrobial agents

2

132

Risk Ratio (M‐H, Random, 95% CI)

1.32 [0.23, 7.55]

7 Need for repeat treatment

0

0

Risk Ratio (M‐H, Random, 95% CI)

0.0 [0.0, 0.0]

Figures and Tables -
Comparison 1. Single dose versus short‐course (4‐7 day) antibiotic for asymptomatic bacteriuria