Drug‐eluting balloon compared with uncoated balloon angioplasty

Patient or population: people with in‐stent restenosis of the femoropopliteal vessels
Setting: hospital
Intervention: drug‐eluting balloon angioplasty
Comparison: uncoated balloon angioplasty

Outcomes

Anticipated absolute effects^* (95% CI)

Relative effect
(95% CI)

№ of participants
(studies)

Quality of the evidence
(GRADE)

Comments

Risk with uncoated balloon angioplasty

Risk with drug‐eluting balloon angioplasty

Amputation

Study population

not estimable

( studies)

0 per 1000

0 per 1000
(0 to 0)

Primary vessel patency

Study population

not estimable

( studies)

0 per 1000

0 per 1000
(0 to 0)

Target lesion revascularization

Study population

not estimable

( studies)

0 per 1000

0 per 1000
(0 to 0)

Binary restenosis

Study population

not estimable

( studies)

0 per 1000

0 per 1000
(0 to 0)

Death

Study population

not estimable

( studies)

0 per 1000

0 per 1000
(0 to 0)

Change in Rutherford category

The mean change in Rutherford category was 0

The mean change in Rutherford category in the intervention group was 0 undefined (0 to 0 )

‐

( studies)

Change in ankle brachial index

The mean change in ankle brachial index was 0

The mean change in ankle brachial index in the intervention group was 0 undefined (0 to 0 )

‐

( studies)

*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).

CI: Confidence interval; RR: Risk ratio

GRADE Working Group grades of evidence
High quality: We are very confident that the true effect lies close to that of the estimate of the effect
Moderate quality: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low quality: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect
Very low quality: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect