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Non‐surgical interventions for nystagmus developing in the first year of life (infantile nystagmus)

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References

Additional references

Abadi 1979

Abadi RV. Visual performance with contact lenses and congenital idiopathic nystagmus. British Journal of Physiological Optics 1979;33:32‐7.

Biousse 2004

Biousse V, Tusa RJ, Russell B, Azran MS, Das V, Schubert MS, et al. The use of contact lenses to treat visually symptomatic congenital nystagmus.. Journal of Neurology, Neurosurgery, and Psychiatry 2004;75(2):314‐6.

Deeks 2011

Deeks JJ, Higgins JPT, Altman DG (editors). Chapter 9: Analysing data and undertaking meta‐analyses. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane‐handbook.org.

Dell'Osso 1975

Dell'Osso LF, Daroff RB. Congenital nystagmus waveforms and foveation strategy. Documenta Ophthalmologica 1975;39:155‐82.

Dell'Osso 1988

Dell'Osso LF, Tracis S, Abel L, Erzurum SI. Contact lenses and congenital nystagmus. Clinical Vision Sciences 1988;3:229‐32.

Dell'Osso 1992

Dell'Osso LF, Leigh RJ. Foveation period stability and oscillopsia suppression in congenital nystagmus. An hypothesis. Neuro‐Ophthalmology 1992;12:169‐83.

Higgins 2011

Higgins JPT, Altman DG, Sterne JAC (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane‐handbook.org. The Cochrane Collaboration.

Lee 2002

Lee J. Surgical management of nystagmus. Journal of the Royal Society of Medicine 2002;95(5):238‐41.

McLean 2012

McLean RJ, Windridge KC, Gottlob I. Living with nystagmus: a qualitative study. British Journal of Ophthalmology 2012;96(7):981‐6.

National Eye Institute 2001

Committee for the Classification of Eye Movement Abnormalities and Strabismus (CEMAS) Workshop. Classification of Eye Movement Abnormalities and Strabismus (CEMAS) ‐ Report of an NEI Sponsored Workshop. Available from http://www.nei.nih.gov/news/statements/cemas.pdf.

Repka 2012

Repka MX, Friedman DS, Katz J, Ibironke J, Giordano L, Tielsch JM. The prevalence of ocular structural disorders and nystagmus among preschool‐aged children. Journal of American Association for Pediatric Ophthalmology and Strabismus 2012;16(2):182‐4.

Review Manager 2014 [Computer program]

The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2014.

Sarvananthan 2009

Sarvananthan N, Surendran M, Roberts EO, Jain S, Thomas S, Shah N, et al. The prevalence of nystagmus: the Leicestershire nystagmus survey. Investigative Ophthalmology & Visual Science 2009;50(11):5201‐6.

Taibbi 2008

Taibbi G, Wang ZI, Dell'Osso LF. Infantile nystagmus syndrome: Broadening the high‐foveation‐quality field with contact lenses. Clinical Ophthalmology 2008;2(3):585‐9.
Table 1. Extracted data template

Participant characteristics

Total number

Gender

Age

Country

Type of nystagmus

Diagnostic criteria

Comorbidities

Baseline binocular visual acuity or changed in best corrected binocular visual acuity

Orthoptic assessment

Participant inclusion and exclusion criteria

Intervention

Intervention

Frequency and treatment length

Study and methodology

Study design

Trial identifiers

Study size

Randomisation

Masking, allocation concealment

Duration of each study

Primary outcomes

Change in best corrected binocular visual acuity (logMAR or Snellen chart)

Secondary outcomes

Estimated visual acuity using visual evoked potentials and/or nystagmus acuity functions such as NAFX

Eye movement recordings using any available technique (e.g. video recording, infrared limbal tracker, electro‐oculography).

Amplitude (mean and minimum); intensity; foveation time; position (mean, minimum mean in foveation window, standard deviation); velocity (mean, minimum mean in foveation window, standard deviation); null zone position and width.

Head posture measured in degrees

Visual recognition times

Patient satisfaction and functional measurements (using validated questionnaires e.g. VFQ‐25)

Economic data and cost analysis data

Adverse outcomes

Adverse effects (minor or major: reduction in visual acuity and blindness; double vision; cognitive effects; death)

Additional data

Treatment compliance and losses to follow‐up

Missing data

Intention‐to‐treat analysis if possible

Trial authors contacted?

Data collection

Microsoft Excel® spreadsheet

Figures and Tables -
Table 1. Extracted data template