Participant characteristics

Total number

Gender

Age

Country

Type of nystagmus

Diagnostic criteria

Comorbidities

Baseline binocular visual acuity or changed in best corrected binocular visual acuity

Orthoptic assessment

Participant inclusion and exclusion criteria

Intervention

Intervention

Frequency and treatment length

Study and methodology

Study design

Trial identifiers

Study size

Randomisation

Masking, allocation concealment

Duration of each study

Primary outcomes

Change in best corrected binocular visual acuity (logMAR or Snellen chart)

Secondary outcomes

Estimated visual acuity using visual evoked potentials and/or nystagmus acuity functions such as NAFX

Eye movement recordings using any available technique (e.g. video recording, infrared limbal tracker, electro‐oculography).

Amplitude (mean and minimum); intensity; foveation time; position (mean, minimum mean in foveation window, standard deviation); velocity (mean, minimum mean in foveation window, standard deviation); null zone position and width.

Head posture measured in degrees

Visual recognition times

Patient satisfaction and functional measurements (using validated questionnaires e.g. VFQ‐25)

Economic data and cost analysis data

Adverse outcomes

Adverse effects (minor or major: reduction in visual acuity and blindness; double vision; cognitive effects; death)

Additional data

Treatment compliance and losses to follow‐up

Missing data

Intention‐to‐treat analysis if possible

Trial authors contacted?

Data collection

Microsoft Excel^® spreadsheet