Bioengineered nerve conduits and wraps for peripheral nerve repair of the upper limb
Información
- DOI:
- https://doi.org/10.1002/14651858.CD012574Copiar DOI
- Base de datos:
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- Cochrane Database of Systematic Reviews
- Versión publicada:
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- 08 marzo 2017see what's new
- Tipo:
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- Intervention
- Etapa:
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- Protocol
- Grupo Editorial Cochrane:
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Grupo Cochrane de Neuromuscular
- Copyright:
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- Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
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Autores
Contributions of authors
SET, MR, AH, and PK conceived the review.
SET drafted the protocol, and MR, AH, PK, LD, and MW revised the draft.
All authors developed the search strategy with assistance from Cochrane team.
All authors have approved publication of the protocol.
Sources of support
Internal sources
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No sources of support supplied
External sources
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Medical Research Council, UK.
Clinical Research Training Fellowship (SET)
Declarations of interest
SET: is currently undertaking a PhD clinical research training fellowship (MRC ‐ 70085) This three years of funding is to support PhD consumables and salary and not a perceived conflict of interest.
NYBN: None known.
MOR: was previously supported by 3b's, but their work has no relation to the review, and there is no ongoing connection. The funded work supports and supported the work in the group towards the development of future conduit, where the outcome is not yet defined. There is no current or developing commercial interest to impact or bias the review process.
PJK: None known.
LBD was previously in receipt of a consulting fee from Axogen Inc, Fl, US during 2009/2010, and there are no ongoing connection. LBD is currently a member of an EU consortium, financially supported by an EU grant, in which Medovent AG (manufacturer of chitosan nerve guides) is also a member. He has received no financial support from this company. Medovent Inc provides chitosan conduits in the Project. He has an active research collaboration with Vibrosense Inc concerning evaluation of vibrotactile sense (Dahlin 2015), which is supported by the foundation VINNOVA, Sweden. He has received no financial support from the company. He has been consultant for AxoGen Inc, Gainsville, FL, USA 2003‐2004. AxoGen Inc produce Avance (R) Nerve Graft, Axoguard((R) Nerve Connector, and Axoguard(R) Nerve Protector. LBD is also a board member of Scania Hand Center AB.
MW was previously in receipt of an AstraTech research funding for the investigation of PHB as a material for use in peripheral nerve repair from 1992‐2008 and received AstraTech funding for a prospective randomised clinical controlled trial of the use of PHB material for wraparound repair of peripheral nerve injuries. The research has been concluded.
AMH previously served on a multicentre wraparound nerve trial design group funded by AstraTech (manufacturer of poly‐3‐hydroxybutyrate sheets for nerve repair), and has been in receipt of a 20,000 GBP nerve research grant from the same company ‐ the grant has been concluded (2007) and there is no existing link. He has worked with NHS Blood & Transplant (NHSBT) in relation to the development of future nerve repair products. He is involved in preparation of a multicentre research project that if successful will involve partnership with NHSBT in application for independent grant funding. At present no financial links have been established, and there has been no joint research output.
Acknowledgements
The authors would like to acknowledge the support of the MRC, which funds the lead author's PhD Fellowship (L70085). We would also like to acknowledge the Information Specialist of Cochrane Neuromuscular, Angela Gunn, who developed the search strategy in consultation with the review authors.
The Methods section of this protocol is based on a template developed by Cochrane Neuromuscular from an original created by the Cochrane Airways Group.
This project was supported by the National Institute for Health Research, via Cochrane Infrastructure funding to Cochrane Neuromuscular. The views and opinions expressed herein are those of the authors and do not necessarily reflect those of the Systematic Reviews Programme, NIHR, NHS or the Department of Health. Cochrane Neuromuscular is also supported by the MRC Centre for Neuromuscular Disease.
Version history
| Published | Title | Stage | Authors | Version |
| 2022 Dec 07 | Bioengineered nerve conduits and wraps for peripheral nerve repair of the upper limb | Review | Suzanne E Thomson, Nigel YB Ng, Mathis O Riehle, Paul J Kingham, Lars B Dahlin, Mikael Wiberg, Andrew M Hart | |
| 2017 Mar 08 | Bioengineered nerve conduits and wraps for peripheral nerve repair of the upper limb | Protocol | Suzanne E Thomson, Nigel YB Ng, Mathis O Riehle, Paul J Kingham, Lars B Dahlin, Mikael Wiberg, Andrew M Hart | |
