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Cochrane Database of Systematic Reviews

Opiáceos para el dolor crónico no relacionado con el cáncer en niños y adolescentes

Información

DOI:
https://doi.org/10.1002/14651858.CD012538.pub2Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 26 julio 2017see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:

  1. Grupo Cochrane de Dolor y cuidados paliativos

Copyright:
  1. Copyright © 2020 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Contraer

Autores

  • Tess E Cooper

    Correspondencia a: Cochrane Kidney and Transplant, Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, Australia

    [email protected]

  • Emma Fisher

    Cochrane Pain, Palliative and Supportive Care Group, Pain Research Unit, Churchill Hospital, Oxford, UK

  • Andrew L Gray

    Division of Pharmacology, Discipline of Pharmaceutical Sciences, University of Kwazulu‐Natal, Congella, South Africa

  • Elliot Krane

    Anaesthesiology, Perioperative & Pain Medicine, and Paediatrics, Stanford University, Stanford, USA

  • Navil Sethna

    Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital, Boston, USA

    Mayo Family Pediatric Pain Rehabilitation Center, Boston Children’s Hospital, Boston, USA

  • Miranda AL van Tilburg

    College of Pharmacy and Health Sciences, Campbell University, Buies Creek, USA

  • Boris Zernikow

    German Paediatric Pain Centre, Children's and Adolescent's Hospital, Datteln, Germany

  • Philip J Wiffen

    Thame, UK

Contributions of authors

TC and PW registered the title.

TC, PW, and Christopher Eccleston wrote the template protocol for the suite of children's reviews, of which this review is a part.

All authors contributed to writing the protocol, and all authors agreed on the final version.

All authors were responsible for data extraction, analysis, and writing of the Discussion for the full review.

All authors will be responsible for the completion of updates.

Sources of support

Internal sources

  • No sources of support supplied

External sources

  • National Institute for Health Research (NIHR), UK.

    NIHR Programme Grant, Award Reference Number: 13/89/29 (Addressing the unmet need of chronic pain: providing the evidence for treatments of pain)

Declarations of interest

PW: none known.

TC: none known.

EF: none known.

AG: none known; AG serves on medicines regulatory and selection bodies, and previously contributed to WHO guidance on the management of pain in children.

EK has received consulting fees for attending a research strategy meeting from Pfizer, Inc. (2015) and for protocol and research consultation from Mallinckrodt Pharmaceuticals, Inc. (2014), AstraZeneca, Inc. (2014), and Collegium Pharma (2016); EK is a specialist paediatric pain clinician and treats patients with chronic pain.

NS has received grants from Gebauer Company for conduct of animal studies using a topical anaesthetic (2015). NS has offered consultant expertise to Pfizer in designing a multi‐center study for use of gabapentin in treatment of neuropathic pain in children (2015). NS is a co‐investigator with an ongoing multi‐center Phase 3 trial of an experimental drug SMNRX [antisense oligonucleotide] for treatment of infants and children with spinal muscle atrophy (2012 to present). NS is an anaesthesiologist and manages paediatric patients with chronic pain.

MvT: none known.

BZ has received personal funding from Grünenthal (2014 to 2016) and Pfizer (2016) in designing and monitoring paediatric investigator plans; BZ is a specialist paediatric pain researcher and clinician and treats patients with cancer pain.

This review was identified in a 2019 audit as not meeting the current definition of the Cochrane Commercial Sponsorship policy. At the time of its publication it was compliant with the interpretation of the existing policy. As with all reviews, new and updated, at update this review will be revised according to 2020 policy update.

Acknowledgements

We acknowledge the contribution of Christopher Eccleston to the template protocol.

We thank Andrew Moore, Cathy Stannard, Neil Schechter, and Marie‐Claude Gregorie for peer reviewing.

Cochrane Review Group funding acknowledgement: the National Institute for Health Research (NIHR) is the largest single funder of the Cochrane Pain, Palliative and Supportive Care Review Group. Disclaimer: the views and opinions expressed herein are those of the authors and do not necessarily reflect those of the NIHR, National Health Service (NHS), or the Department of Health.

Version history

Published

Title

Stage

Authors

Version

2017 Jul 26

Opioids for chronic non‐cancer pain in children and adolescents

Review

Tess E Cooper, Emma Fisher, Andrew L Gray, Elliot Krane, Navil Sethna, Miranda AL van Tilburg, Boris Zernikow, Philip J Wiffen

https://doi.org/10.1002/14651858.CD012538.pub2

2017 Feb 09

Opioids for chronic non‐cancer pain in children and adolescents

Protocol

Tess E Cooper, Emma Fisher, Andrew L Gray, Elliot Krane, Navil Sethna, Miranda AL van Tilburg, Boris Zernikow, Philip J Wiffen

https://doi.org/10.1002/14651858.CD012538

Differences between protocol and review

Minor changes to the wording of the Background section and details of examples.

We did not consider studies with fewer than 10 participants per treatment arm for inclusion in this review, as is standard practice for this group.

Notes

A restricted search in March 2019 did not identify any potentially relevant studies likely to change the conclusions. Therefore, this review has now been stabilised following discussion with the authors and editors. The review will be re‐assessed for updating in five years. If appropriate, we will update the review before this date if new evidence likely to change the conclusions is published, or if standards change substantially which necessitates major revisions.

Keywords

MeSH

Medical Subject Headings (MeSH) Keywords

Medical Subject Headings Check Words

Adolescent; Child; Child, Preschool; Humans; Infant; Infant, Newborn;

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.

Study flow diagram.
Figuras y tablas -
Figure 1

Study flow diagram.

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