Platelet transfusion compared with no platelet transfusion for lumbar puncture procedures

Patient or population: People with thrombocytopenia

Intervention: Platelet transfusion

Comparison: No platelet transfusion

Major procedure‐related bleeding within 24 hours of the procedure

Not estimated

150

(2 studies)

⊕⊝⊝⊝

Very low ^{1, 2}

All‐cause mortality up to 30 days after the procedure

‐

‐

‐

Not reported

Transfusion‐related complications within 24 hours of the procedure

‐

‐

‐

Not reported

Procedure‐related (lumbar puncture or epidural anaesthetic) complications within 7 days of the procedure

Not estimated

21

(1 study)

⊕⊝⊝⊝

Very low^{1, 2}

Quality of life (as defined by the individual studies)

‐

‐

‐

Not reported

*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval

GRADE Working Group grades of evidence
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. The initial rating was 'low' as all included studies were non‐randomised studies.
Very low quality: We are very uncertain about the estimate.