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Cochrane Database of Systematic Reviews

Intervenciones para el tratamiento de la colestasis intrahepática en pacientes con anemia de células falciformes

Esta versión no es la más reciente

ver la versión actual 22 junio 2020

Información

DOI:
https://doi.org/10.1002/14651858.CD010985.pub3Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 31 julio 2017see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:

  1. Grupo Cochrane de Fibrosis quística y enfermedades genéticas

Copyright:
  1. Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

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Contraer

Autores

Contributions of authors

Arturo  Martí‐Carvajal conceived the review question, developed and coordinated the review, completed the first draft of the review, approved the final version of the review prior to submission.
Cristina Martí‐Amarista: approved the final version of the review prior to submission and is guarantor for the review.

Sources of support

Internal sources

  • No sources of support supplied

External sources

  • Iberoamerican Cochrane Center, Spain.

    Academic.

  • National Institute for Health Research, UK.

    This systematic review was supported by the National Institute for Health Research, via Cochrane Infrastructure funding to the Cochrane Cystic Fibrosis and Genetic Disorders Group.

Declarations of interest

Arturo Martí‐Carvajal:
In 2004 he was employed by Eli Lilly to run a four‐hour workshop on 'How to critically appraise clinical trials on osteoporosis and how to teach this'. This activity was not related to his work with the Cochrane Collaboration or any Cochrane Review.

In 2007 he was employed by Merck to run a four‐hour workshop 'How to critically appraise clinical trials and how to teach this'. This activity was not related to his work with the Cochrane Collaboration or any Cochrane Review.

Cristina Martí‐Amarista: none known.

Acknowledgements

We want to express our gratitude to Cystic Fibrosis and Genetic Disorders Group and peer reviewers for improving the quality of this Cochrane Review.

This project was supported by the National Institute for Health Research, via Cochrane Infrastructure funding to the Cochrane Cystic Fibrosis and Genetic Disorders Group. The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the Systematic Reviews Programme, NIHR, NHS or the Department of Health.

Version history

Published

Title

Stage

Authors

Version

2020 Jun 22

Interventions for treating intrahepatic cholestasis in people with sickle cell disease

Review

Arturo J Martí-Carvajal, Cristina Elena Martí-Amarista

https://doi.org/10.1002/14651858.CD010985.pub4

2017 Jul 31

Interventions for treating intrahepatic cholestasis in people with sickle cell disease

Review

Arturo J Martí‐Carvajal, Cristina Elena Martí‐Amarista

https://doi.org/10.1002/14651858.CD010985.pub3

2015 Mar 13

Interventions for treating intrahepatic cholestasis in people with sickle cell disease

Review

Arturo J Martí‐Carvajal, Daniel Simancas‐Racines

https://doi.org/10.1002/14651858.CD010985.pub2

2014 Feb 13

Interventions for treating intrahepatic cholestasis in people with sickle cell disease

Protocol

Arturo J Martí‐Carvajal, Daniel Simancas‐Racines

https://doi.org/10.1002/14651858.CD010985

Differences between protocol and review

Based on two suggestions made by a peer reviewer and approved by editorial base, we did two changes:

1. To remove hydroxyurea as potential pharmacological intervention for treating intrahepatic cholestasis in SCD.

2. We included platelet count as secondary outcome. Therefore, we amended the 'Measures of treatment effect' section: "For continuous outcomes, such as quality of life, and relief of fatigue, the authors will calculate standardized mean difference (SMD) with the corresponding 95% CI, if those outcomes are measured with different scales. On the contrary, either platelet count or quality of life, and relief of fatigue we plan to calculate mean difference (MD) with the corresponding 95% CI".

We were unable to search on African Index Medicus (http://indexmedicus.afro.who.int/). This web site displayed the following message "Access Denied (license_expired). A license has expired on the Proxy, and your request is not permitted: "The SGOS license has expired". For assistance, contact your network support team." (Accessed: 23 May 2017).

Keywords

MeSH

Medical Subject Headings (MeSH) Keywords

Medical Subject Headings Check Words

Humans;

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.