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Referencias

Alkhajah 2012 {published data only}

Alkhajah TA, Reeves MM, Eakin EG, Winkler EA, Owen N, Healy GN. Sit‐stand workstations: a pilot intervention to reduce office sitting time. American Journal of Preventive Medicine 2012;43(3):298‐303. CENTRAL
Healy G, Alkhajah T, Winkler E, Owen N, Eakin E. Reducing sitting time in office workers: efficacy and acceptability of sit‐stand workstations. Journal of Science and Medicine in Sport 2012;15:S196. CENTRAL

Brakenridge 2016 {published data only}

ACTRN12614000252617. Comparison of organisational support vs. organisational plus technology support for reducing prolonged sitting in office workers. https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=365886 (accessed 12 September 2017). CENTRAL
Brakenridge CL, Fjeldsoe BS, Young DC, Winkler EA, Dunstan DW, Straker LM. Evaluating the effectiveness of organisational‐level strategies with or without an activity tracker to reduce office workers' sitting time: a cluster‐randomised trial. International Journal of Behavioural Nutrition and Physical Activity 2016;13(1):115. CENTRAL
Brakenridge CL, Fjeldsoe BS, Young DC, Winkler EA, Dunstan DW, Straker LM. Organizational level strategies with or without an activity tracker to reduce office workers' sitting time: rationale and study design of a pilot cluster‐randomized trial. JMIR research protocols 2016;5(2):e73. CENTRAL

Carr 2015 {published data only}

Carr LJ, Leonhard C, Tucker S, Fethke N, Benzo R, Gerr F. Total worker health intervention increases activity of sedentary workers. American Journal of Preventive Medicine 2015;49:[Epub ahead of print]. CENTRAL
NCT02071420. Efficacy of a combined ergonomic health promotion intervention on employee health. https://clinicaltrials.gov/ct2/show/NCT02071420 (accessed 28 November 2015). CENTRAL

Chau 2014 {published data only}

ACTRN12612000072819. The Stand@Work Pilot Study. A randomised controlled trial to see if using sit‐stand workstations reduces sitting time in office workers. https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12612000072819 (accessed 3 June 2015). CENTRAL
Chau JY, Daley M, Dunn S, Srinivasan A, Do A, Bauman AE, et al. The effectiveness of sit‐stand workstations for changing office workers' sitting time: results from the Stand@Work randomized controlled trial pilot. International Journal of Behavioral Nutrition and Physical Activity 2014;11:127. CENTRAL
Chau JY, Daley M, Srinivasan A, Dunn S, Bauman AE, van der Ploeg HP. Desk‐based workers’ perspectives on using sit‐stand workstations: a qualitative analysis of the Stand@Work study. BMC Public Health 2014;14:752. CENTRAL

Chau 2016 {published data only}

Chau JY, Sukala W, Fedel K, Do A, Engelen L, Kingham M, et al. More standing and just as productive: effects of a sit‐stand desk intervention on callcenter workers’ sitting, standing, and productivity at work in the Opt to Standpilot study. Preventive Medicine Reports 2016;3:68‐74. CENTRAL

Coffeng 2014 {published data only}

Coffeng JK, Boot CR, Duijts SF, Twisk JW, van Mechelen W, Hendriksen IJ. Effectiveness of a worksite social & physical environment intervention on need for recovery, physical activity and relaxation; results of a randomized controlled trial. PLoS ONE 2014;9(12):e114860. CENTRAL
Coffeng JK, Hendriksen IJ, Duijts SF, Proper KI, Mechelen WV, Boot CRL. The development of the Be Active & Relax "Vitality in Practice" (VIP) project and design of an RCT to reduce the need for recovery in office employees. BMC Public Health 2012;12:592. CENTRAL
Coffeng JK, Hendriksen IJ, van Mechelen W, Boot CR. Process evaluation of a worksite social and physical environmental intervention. Journal of Occupational and Environmental Medicine 2013;55(12):1409‐20. CENTRAL
Coffeng JK, Hendriksen IJM, Duijts SFA, Twisk JWR, Van Mechelen W, Boot CRL. Effectiveness of a combined social and physical environmental intervention on presenteeism, absenteeism, work performance and work engagement in office employees. Journal of Occupational Environment Medicine in press; Vol. 56, issue 3:258‐65. CENTRAL
NTR2553. The cost‐effectiveness of an intervention to increase physical activity and relaxation amongst office workers. http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2553 (accessed 3 June 2014). CENTRAL

Danquah 2017 {published data only}

Danquah IH, Kloster S, Holtermann A, Aadahl M, Bauman A, Ersbøll AK, et al. Take a Stand!‐a multi‐component intervention aimed at reducing sitting time among office workers‐a cluster randomized trial. International Journal of Epidemiology 2017;46(1):128–40. CENTRAL
Danquah IH, Kloster S, Holtermann A, Aadahl M, Tolstrup JS. Effects on musculoskeletal pain from “Take a stand!” – A cluster‐randomized controlled trial reducing sitting time among office workers. Scandinavian Journal of Work, Environment and Health. 2017;43(4):350‐7. CENTRAL
NCT01996176. Take a Stand! ‐ an intervention to reduce occupational sitting time. https://clinicaltrials.gov/ct2/show/NCT01996176 (accessed 12 September 2017). CENTRAL

De Cocker 2016 {published data only}

De Cocker K, De Bourdeaudhuij I, Cardon G, Vandelanotte C. The effectiveness of a web‐based computer‐tailored intervention on workplace sitting: a randomized controlled trial. Journal of Medical Internet Research 2016;18(5):e96. CENTRAL
De Cocker Katrien, De Bourdeaudhuij I, Cardon G, Vandelanotte C. What are the working mechanisms of a web‐based workplace sitting intervention targeting psychosocial factors and action planning?. BMC Public Health 2017;1:382. CENTRAL
NCT02672215. RCT Computer‐tailored intervention on workplace sitting (StartToStand). https://clinicaltrials.gov/ct2/show/NCT02672215 (accessed 12 September 2017). CENTRAL

Donath 2015 {published data only}

Donath L, Faude O, Schefer Y, Roth R, Zahner L. Repetitive daily point of choice prompts and occupational sit‐stand transfers, concentration and neuromuscular performance in office workers: an RCT. International Journal of Environmental Research and Public Health 2015;12(4):4340‐53. CENTRAL

Dutta 2014 {published data only}

Dutta N, Koepp GA, Stovitz SD, Levine JA, Pereira MA. Using sit‐stand workstations to decrease sedentary time in office workers: a randomized crossover trial. International Journal of Environmental Research and Public Health 2014;11(7):6653‐65. CENTRAL
Dutta N, Walton T, Pereira MA. Experience of switching from a traditional sitting workstation to a sit‐stand workstation in sedentary office workers. Work 2014;52(1):83‐9. CENTRAL

Ellegast 2012 {published and unpublished data}

Ellegast R, Weber B, Mahlberg R. Method inventory for assessment of physical activity at VDU workplaces. Work. 2012; Vol. 41, issue suppl 1:2355‐9. CENTRAL
Mahlberg R. Entwicklung und Erprobung eines arbeitsmedizinischen Methodeninventars zur Effektivitätsanalyse von Präventionsmassnahmen zur Vermeidung von Muskel‐Skelett Erkrankungen an bewegungsarmen Arbeitsplätzen. Hohen Medizinischen Fakultät der Ruhr‐Universität Bochum. PhD dissertation2011. CENTRAL

Evans 2012 {published data only}

Evans RE, Fawole HO, Sheriff SA, Dall PM, Grant PM, Ryan CG. Point‐of‐choice prompts to reduce sitting time at work: a randomised trial. American Journal of Preventive Medicine 2012 Sep;43(3):293‐7. CENTRAL
NCT01628861. Point‐of‐choice prompts to reduce prolonged sitting time at work. http://clinicaltrials.gov/ct2/show/NCT01628861 (accessed 15 March 2014). CENTRAL

Gao 2015 {published data only}

Gao Y, Nevala N, Cronin NJ, Finni T. Effects of environmental intervention on sedentary time, musculoskeletal comfort and work ability in office workers. European Journal of Sport Science 2015;(Epub ahead of print):1‐8. CENTRAL
ISRCTN43848163. Can an adjustable workstation reduce occupational sedentary time?. http://www.isrctn.com/ISRCTN43848163 (accessed 3 June 2015). CENTRAL

Gilson 2009 {published data only}

Gilson ND, Puig‐Ribera A, McKenna J, Brown WJ, Burton NW, Cooke CB. Do walking strategies to increase physical activity reduce reported sitting in workplaces: a randomised control trial. International Journal of Behavioral Nutrition and Physical Activity 2009;6:43. CENTRAL

Gordon 2013 {published data only}

Gordon A. A theory‐based pilot study to decrease sitting time in the workplace. A theory‐based pilot study to decrease sitting time in the workplace (Msc Thesis). Arizona: Arizona State University, 2013. CENTRAL

Graves 2015 {published data only}

Graves LEF, Murphy RC, Shepherd SO, Cabot J, Hopkins ND. Evaluation of sit‐stand workstations in an office setting: a randomised controlled trial. BMC Public Health 2015;15(1):1145. CENTRAL
NCT02496507. A mixed‐methods evaluation of sit‐stand workstations in an office setting. https://clinicaltrials.gov/ct2/show/NCT02496507 (accessed 1 December 2015). CENTRAL

Healy 2013 {published data only}

Healy GN, Eakin EG, Lamontagne AD, Owen N, Winkler EA, Wiesner G, et al. Reducing sitting time in office workers: short‐term efficacy of a multi component intervention. Preventive Medicine 2013;57(1):43‐8. CENTRAL
Neuhaus M, Healy G, Eakin E, FJeldsoe B, Lamontagne A, Owen N, et al. Efficacy of an integrated approach to reduce sitting time in office workers. Journal of Science and Medicine in Sport 2012;15:S197. CENTRAL
Stephens SK, Winkler EA, Trost SG, Dunstan DW, Eakin EG, Chastin SF, et al. Intervening to reduce workplace sitting time: how and when do changes to sitting time occur?. British Journal of Sports Medicine 2014;48(13):1037‐42. CENTRAL

Healy 2016 {published data only}

ACTRN12611000742976. In office workers, does environmental modification combined with behavioural counselling, compared to no change, lead to reductions in workplace sitting time. https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12611000742976 (accessed 12 September 2017). CENTRAL
Healy GN, Eakin EG, Owen N, Lamontagne AD, Moodie M, Winkler EA. A cluster randomized controlled trial to reduce office workers' sitting time: effect on activity outcomes. Medicine and Science in Sports and Exercise 2016;48(9):1787‐97. CENTRAL
Winkler EA, Chastin S, Eakin EG, Owen N, LaMontagne AD, Moodie M. Cardiometabolic impact of changing sitting, standing, and stepping in the workplace. Medicine and Science in Sports and Exercise 2017;50(3):516‐24. CENTRAL

Kress 2014 {published data only}

Kress MM. The use of stand‐capable workstations for reducing sedentary time in office employees. Dissertation Abstracts International: Section B: The Sciences and Engineering 2015;76:6‐B(E). CENTRAL
Kress MM. The use of stand‐capable workstations for reducing sedentary time in office employees. Doctoral dissertation, Texas A & M University.2014. CENTRAL

Li 2017 {published data only}

ACTRN12615001018505. Examining different sit‐stand protocols in terms of health and behavioural outcomes: an office‐based pilot study. https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=369210 (accessed 12 September 2017). CENTRAL
Li I, Mackey MG, Foley B, Pappas E, Edwards K, Chau JY, et al. Reducing office workers' sitting time at work using sit‐stand protocols: results from a pilot randomized controlled trial. Journal of Occupational Environmental Medicine 2016;59(6):543‐9. CENTRAL

MacEwen 2017 {published data only}

MacEwen BT, Saunders TJ, MacDonald DJ, Burr JF. Sit‐stand desks to reduce workplace sitting time In office workers with abdominal obesity: a randomized controlled trial. Journal of Physical Activity and Health 2017;17:1‐18. CENTRAL
NCT02342301. Cardiometabolic Response to Sit‐stand Workstations. https://clinicaltrials.gov/ct2/show/NCT02342301 (accessed 12 September 2017). CENTRAL

Mailey 2016 {published data only}

Mailey EL, Rosenkranz SK, Casey K, Swank A. Comparing the effects of two different break strategies on occupational sedentary behavior in a real world setting. Preventive Medicine Reports 2016;4:423‐8. CENTRAL
NCT02609438. An intervention to reduce sitting time at work: effects on metabolic health and inactivity (Up4Health). https://clinicaltrials.gov/ct2/show/NCT02609438 (accessed 12 September 2017). CENTRAL

Neuhaus 2014a {published data only}

ACTRN12612001246875. Reducing sitting time in office workers: comparison of a multifaceted workplace approach vs. installation of height‐adjustable desks only using a three‐armed controlled trial. http://www.anzctr.org.au/ACTRN12612001246875.aspx (accessed 15 March 2014). CENTRAL
Neuhaus M, Healy GN, Dunstan DW, Owen N, Eakin EG. Workplace sitting and height‐adjustable workstations: a randomised controlled trial. American Journal of Preventive Medicine 2014;46(1):30‐40. CENTRAL

Pedersen 2013 {published and unpublished data}

Cooley D, Pedersen S, Mainsbridge C. Assessment of the impact of a workplace intervention to reduce prolonged occupational sitting time. Qualitative Health Research 2014;24(1):90‐101. CENTRAL
Pedersen SJ, Cooley PD, Mainsbridge C. An e‐health intervention designed to increase workday energy expenditure by reducing prolonged occupational sitting habits. Work 2014;49(2):289‐95. CENTRAL

Pickens 2016 {published data only}

Pickens AW, Kress MM, Benden ME, Zhao H, Wendel M, Congleton JJ. Stand‐capable desk use in a call center:a six‐month follow‐up pilot study. Public Health 2016;135:131‐4. CENTRAL

Priebe 2015 {published data only}

Priebe CS, Spink KS. Less sitting and more moving in the office: using descriptive norm messages to decrease sedentary behavior and increase light physical activity at work. Psychology of Sport and Exercise 2015;19:76‐84. CENTRAL

Puig‐Ribera 2015 {published and unpublished data}

NCT02960750. Effectiveness of a workplace "Sit Less and Move More" web‐based program (Walk@WorkSpain) on occupational sedentary behavior, habitual physical activity, physical risk factors for chronic disease and efficiency‐related outcomes in Spanish office employees. https://clinicaltrials.gov/ct2/show/NCT02960750 (accessed 12 September 2017). CENTRAL
Puig‐Ribera A, Bort‐Roig J, Gine‐Garriga M, Gonzalez‐Suarez AM, Martinez‐Lemos I, Fortuno J, et al. Impact of a workplace 'sit less, move more' program on efficiency‐related outcomes of office employees. BMC Public Health 2017;17(1):455. CENTRAL
Puig‐Ribera A, Bort‐Roig J, González‐Suárez AM, Martínez‐Lemos I, Giné‐Garriga M, Fortuño J, et al. Patterns of impact resulting from a 'sit less, move more' web‐based program in sedentary office employees. PLoS One 2015;10(4):e01224. CENTRAL
Roig JB, Horcajo MM, Ribera AP, Gonzalez Á, Lemos IM. Walk and Work Spain: Participants’ perspectives and experiences on reducing occupational sitting time. Journal of Science and Medicine in Sport 2012;15(Supplement 1):S303. CENTRAL

Sandy 2016 {published data only}

Sandy ME. Longitudinal Study of Adjustable Workstations. Graduate Theses and Dissertations2016. CENTRAL

Schuna 2014 {published and unpublished data}

NCT01587092. Workstation Pilot Study. https://clinicaltrials.gov/ct2/show/NCT01587092 (accessed 3 June 2014). CENTRAL
Schuna JM, Swift DL, Hendrick CA, Duet MT, Johnson WD, Martin CK, et al. Evaluation of a workplace treadmill desk intervention: a randomized controlled trial. Journal of Occupational and Environmental Medicine 2014;56(12):1266‐76. CENTRAL
Tudor‐Locke C, Hendrick CA, Duet MT, Swift DL, Schuna JM, Martin CK, et al. Implementation and adherence issues in a workplace treadmill desk intervention. Applied Physiology, Nutrition, and Metabolism 2014;39(10):1104‐11. CENTRAL

Swartz 2014 {published data only}

Swartz AM, Rote AE, Welch WA, Maeda H, Hart TL, Cho YI, et al. Prompts to disrupt sitting time and increase physical activity at work. Centers for Disease Control and Prevention, Preventing Chronic Disease 2014;11:E73. CENTRAL

Tobin 2016 {published data only}

Tobin R, Leavy J, Jancey J. Uprising: An examination of sit‐stand workstations, mental health and work ability in sedentary office workers, in Western Australia. Work 2016;55(2):359‐71. CENTRAL

Urda 2016 {published data only}

Urda JL, Lynn JS, Gorman A, Larouere B. Effects of a minimal workplace intervention to reduce sedentary behaviors and improve perceived wellness in middle‐aged women office workers. Journal of Physical Activity and Health 2016;13:838‐44. CENTRAL

van Berkel 2014 {published data only}

van Berkel J, Boot CR, Proper KI, Bongers PM, van der Beek AJ. Effectiveness of a worksite mindfulness‐related multi‐component health promotion intervention on work engagement and mental health: results of a randomised controlled trial. PLoS ONE 2014;9(1):e84118. CENTRAL
van Berkel J, Boot CR, Proper KI, Bongers PM, van der Beek AJ. Mindful "Vitality in Practice": an intervention to improve the work engagement and energy balance among workers; the development and design of the randomised controlled trial. BMC Public Health 2011;11:736. CENTRAL
van Berkel J, Boot CR, Proper KI, et al. Effectiveness of a worksite mindfulness‐based multi‐component intervention on lifestyle behaviours. International Journal of Behavioral Nutrition and Physical Activity2014; Vol. 11. CENTRAL

Verweij 2012 {published data only}

ISRCTN73545254. Balance@Work: the cost effectiveness of an occupational health guideline to improve physical activity and dietary behaviour among workers in order to prevent weight gain. http://www.isrctn.com/ISRCTN73545254 2009 (accessed 28 November 2015). CENTRAL
Verweij LM, Proper KI, Weel AN, Hulshof CT, van Mechelen W. Design of the Balance@Work project: systematic development, evaluation and implementation of an occupational health guideline aimed at the prevention of weight gain among employees. BMC Public Health 2009;9:461. CENTRAL
Verweij LM, Proper KI, Weel AN, Hulshof CT, van Mechelen W. Long‐term effects of an occupational health guideline on employees' body weight‐related outcomes, cardiovascular disease risk factors, and quality of life: results from a randomised controlled trial. Scandinavian Journal of Work, Environment & Health 2013;39(3):284‐94. CENTRAL
Verweij LM, Proper KI, Weel AN, Hulshof CT, van Mechelen W. The application of an occupational health guideline reduces sedentary behaviour and increases fruit intake at work: results from an RCT. Occupational and Environmental Medicine 2012;69(7):500‐7. CENTRAL
van Wier MF, Verweij LM, Proper KI, Hulshof CT, van Tulder MW, van Mechelen W. Economic evaluation of an occupational health care guideline for prevention of weight gain among employees. Journal of occupational and environmental medicine 2013;55(9):1100. CENTRAL

References to studies excluded from this review

Aadahl 2015 {published data only}

Aadahl M, Linneberg A, Møller TC, Rosenørn S, Dunstan DW, Witte DR, et al. Motivational counselling to reduce sitting time: a community‐based randomized controlled trial in adults. American Journal of Preventive Medicine 2015;47(5):576‐86. CENTRAL
NCT00289237. Lifestyle intervention in a general population for prevention of ischaemic heart disease. https://clinicaltrials.gov/show/NCT00289237 2012 (accessed 1 December 2015). CENTRAL

Adams 2012 {published data only}

Adams 2012. On our feet: Feasibility trial of an intervention to reduce sedentary behavior and increase physical activity (PhD Thesis). Greensboro: The University of North Carolina, 2012. CENTRAL
Melanie M. Adams MM, Davis PG, Gill DL. A hybrid online intervention for reducing sedentary behavior in obese women. Frontiers in Public Health 2013;1:45. CENTRAL

Aittasalo 2004 {published data only}

Aittasalo M, Miilunpalo S, Suni J. The effectiveness of physical activity counselling in a work‐site setting. A randomised, controlled trial. Patient Education and Counselling 2004;55(2):193‐202. CENTRAL

Alderman 2014 {published data only}

Alderman BL, Olson RL, Mattina DM. Cognitive function during low‐intensity walking: a test of the treadmill workstation. Journal of Physical Activity and Health 2014;11(4):752‐8. CENTRAL

Arrogi 2017 {published data only}

Arrogi A, Schotte A, Bogaerts A, Boen F, Seghers J. Short‐ and long‐term effectiveness of a three‐month individualized need‐supportive physical activity counseling intervention at the workplace.. BMC Public Health 2017;17(1):52. CENTRAL

Audrey 2015 {published data only}

Audrey S, Cooper AR, Hollingworth W, Metcalfe C, Procter S, Davis A, et al. Study protocol: the effectiveness and cost effectiveness of an employer‐led intervention to increase walking during the daily commute: the Travel to Work randomised controlled trial. BMC public Health 2015;15:154. CENTRAL

Barbieri 2017 {published data only}

Barbieri DF, Srinivasan D, Mathiassen SE, Oliveira AB. Comparison of sedentary behaviors in office workers using sit‐stand tables with and without semiautomated position changes. Human Factors 2017;59(5):782‐95. CENTRAL

Ben‐Ner 2014 {published data only}

Ben‐Ner A, Hamann DJ, Koepp G, Manohar CU, Levine J. Treadmill workstations: the effects of walking while working on physical activity and work performance. PLoS ONE 2014;9(2):e88620. CENTRAL

Berberien 2016 {published data only}

Berberien V, Lowensteyn I. Evaluating the impact of a workplace wellness program on women: the experience at Merck Canada after one year. Canadian Journal of Cardiology 2016;32(4):S1‐S2. CENTRAL

Biddle 2015 {published data only}

Biddle SJ, Edwardson CL, Wilmot EG, Yates T, Gorely T, Bodicoat DH, et al. A randomised controlled trial to reduce sedentary time in young adults at risk of Type 2 Diabetes Mellitus: project STAND (Sedentary Time ANd Diabetes). PloS One 2015;10(12):e0143398. CENTRAL

Bird 2014 {published data only}

Bird ML, Shing C, Mainsbridge C, Cooley D, Pederson S. Activity behaviours of University staff in the workplace: A pilot study. Journal of Physical Activity and Health 2014 [Epub ahead of print];12(8):1128‐32. CENTRAL

Bjorklund 2015 {published data only}

Bjorklund M, Tronarp R, Granas M, Dahlgren G, McDonough S, Nyberg A, et al. Office‐cycling while working: an innovative concept to prevent and reduce musculoskeletal pain in office workers‐a controlled feasibility study. Physiotherapy 2015;101:eS155‐6. CENTRAL

Boreham 2005 {published data only}

Boreham CA, Kennedy RA, Murphy MH, Tully M, Wallace WF, Young I. Training effects of short bouts of stair climbing on cardiorespiratory fitness, blood lipids, and homocysteine in sedentary young women. British Journal of Sports Medicine 2005;39(9):590‐3. CENTRAL

Bouchard 2015 {published data only}

Bouchard DR, Strachan S, Johnson L, Moola F, Chitkara R, McMillan D, et al. Using shared treadmill workstations to promote less time spent in daily low intensity physical activities: A pilot study. Journal of Physical Activity and Health 2015;8:[Epub ahead of print]. CENTRAL

Brown 2012 {published data only}

Brown DK, Barton JL, Pretty J, Gladwell VF. Walks4work: rationale and study design to investigate walking at lunchtime in the workplace setting. BMC Public Health 2012;12:550. CENTRAL

Buchholz 2016 {published data only}

Buchholz SW, Ingram D, Wilbur J, Fogg L, Sandi G, Moss A, et al. Bilingual Text4Walking food service employee intervention pilot study. JMIR mHealth and uHealth 2016;4(2):e68. CENTRAL

Carr 2013 {published data only}

Carr LJ, Karvinen K, Peavler M, Smith R, Cangelosi K. Multicomponent intervention to reduce daily sedentary time: a randomised controlled trial. BMJ 2013;3(10):e003261. CENTRAL

Carter 2015 {published data only}

Carter SE, Jones M, Gladwell VF. Energy expenditure and heart rate response to breaking up sedentary time with three different physical activity interventions. Nutrition Metabolism and Cardiovascular Diseases 2015;25(5):503‐9. CENTRAL

Chae 2015 {published data only}

Chae D, Kim S, Park Y, Hwang Y. The effects of an academic‐workplace partnership intervention to promote physical activity in sedentary office workers. Workplace Health & Safety 2015;63(6):259‐66. CENTRAL

Cheema 2013 {published data only}

Cheema BS, Houridis A, Busch L, Raschke‐Cheema V, Melville GW, Marshall PW, et al. Effect of an office worksite‐based yoga program on heart rate variability: outcomes of a randomised controlled trial. BMC Complementary and Alternative Medicine 2013;13:82. CENTRAL
Cheema BS, Marshall PW, Chang D, Colagiuri B, Machliss B. Effect of an office worksite‐based yoga program on heart rate variability: a randomised controlled trial. BMC Public Health 2011;11:578. CENTRAL

Chia 2015 {published data only}

Chia M, Chen B, Suppiah H. Office sitting made less sedentary – A future‐forward approach to reducing physical inactivity at work. Montenegrin Journal of Sports Science and Medicine 2015;4(2):5‐10. CENTRAL

Cifuentes 2015 {published data only}

Cifuentes M, Jin Q, Fulmer S, Bello A. Facilitators and barriers to using treadmill workstations under real working conditions: a qualitative study in female office workers. American Journal of Health Promotion 2015;30(2):93‐100. CENTRAL

Clemes 2014 {published data only}

Clemes SA, Patel R, Mahon C, Griffiths PL. Sitting time and step counts in office workers. Occupational Medicine 2014;64(3):188‐92. CENTRAL

DeCocker 2015 {published data only}

De Cocker K, De Bourdeaudhuij I, Cardon G, Vandelanotte C. Theory‐driven, web‐based, computer‐tailored advice to reduce and interrupt sitting at work: development, feasibility and acceptability testing among employee. BMC Public Health 2015;15(100968562):959. CENTRAL

Dewa 2009 {published data only}

Dewa CS, de Ruiter W, Chau N, Karioja K. Walking for wellness: using pedometers to decrease sedentary behaviour and promote mental health. International Journal of Mental Health Promotion 2009;11(2):24‐8. CENTRAL

Elmer 2014 {published data only}

Elmer SJ, Martin JC. A cycling workstation to facilitate physical activity in office settings. Applied Ergonomics 2014;45(4):1240‐6. CENTRAL

Engelen 2017 {published data only}

Engelen L, Chau J, Bohn‐Goldbaum E, Young S, Hespe D, Bauman A. Is Active Design changing the workplace? ‐ a natural pre‐post experiment looking at health behaviour and workplace perceptions. Work 2017;56(2):229‐37. CENTRAL

Fennell 2017 {published data only}

Fennell C. The effects of a 16‐week exercise program and cell phone use on physical activity, sedentary behavior, and health‐related outcomes. Dissertation Abstracts International: Section B: The Sciences and Engineering 2017;78:3‐B(E). CENTRAL

Foley 2016 {published data only}

Foley B, Engelen L, Gale J, Bauman A, Mackey M. Sedentary behavior and musculoskeletal discomfort are reduced when office workers trial an activity based work environment. Journal of Occupational & Environmental Medicine 2016;58(9):924‐31. CENTRAL

Freak‐Poli 2011 {published data only}

Freak‐Poli R, Wolfe R, Backholer K, de Courten M, Peeters A. Impact of a pedometer‐based workplace health program on cardiovascular and diabetes risk profile. Preventive Medicine 2011;53(3):162‐71. CENTRAL

Ganesan 2016 {published data only}

Ganesan AN, Louise J, Horsfall M, Bilsborough SA, Hendriks J, McGavigan AD, et al. International mobile‐health intervention on physical activity, sitting, and weight: the Stepathlon cardiovascular health study. Journal of the American College of Cardiology 2016;67(21):2453‐63. CENTRAL

Gardner 2015 {published data only}

Gardner B, Smith L, Aggio D, Iliffe S, Fox KR, Jefferis BJ, et al. 'On Your Feet to Earn Your Seat': update to randomised controlled trial protocol. Trials 2015;16:330. CENTRAL

Gilson 2012 {published data only}

Gilson N, Faulker G, Murphy M, Umstattd Meyer M, Ryde G, McCarthy K, et al. An international study of an automated web‐based walking program (Walk@Work) to increase workday step counts in lower active office workers. Journal of Science and Medicine in Sport 2012;15:S235‐6. CENTRAL

Gilson 2015 {published data only}

Gilson N, Ng N, Pavey T, Ryde G, Straker L, Brown W. Project energise: the impact of real‐time prompts on sedentary and physically active work time in Australian office workers. Journal of Science and Medicine in Sport 2015;19:e10. CENTRAL

Gilson ND 2012 {published data only}

Gilson N, Suppini A, Ryde G, Brown H, Brown W. Do height adjustable 'hot' desks change sedentary work behaviour in an open plan office?. Journal of Science and Medicine in Sport 2011;14:e24‐5. CENTRAL
Gilson ND, Suppini A, Ryde GC, Brown HE, Brown WJ. Does the use of standing 'hot' desks change sedentary work time in an open plan office?. Preventive Medicine 2012;54(1):65‐7. CENTRAL

Gorman 2013 {published data only}

Gorman E, Ashe MC, Dunstan DW, Hanson HM, Madden K, Winkler EA, et al. Does an 'activity‐permissive' workplace change office workers' sitting and activity time?. PLoS One 2013;8(10):e76723. CENTRAL

Green 2016 {published data only}

Green N, Sigurdsson S, Wilder DA. Decreasing bouts of prolonged sitting among office workers. Journal of Applied Behavior Analysis 2016;49(3):717‐22. CENTRAL

Grunseit 2012 {published data only}

Grunseit A, Chau J, Van der Ploeg H, Bauman A. Thinking on your feet: a qualitative evaluation of an installation of sit‐stand desks in a medium‐sized workplace. Journal of Science and Medicine in Sport 2012;15:S195‐6. CENTRAL

Hadgraft 2017 {published data only}

Hadgraft NT, Winkler EA, Healy GN, Lynch BM, Neuhaus, M, Eakin EG, et al. Intervening to reduce workplace sitting: mediating role of social‐cognitive constructs during a cluster randomised controlled trial. International Journal of Behavioral Nutrition and Physical Activity 2017;14(1):27. CENTRAL

Hedge 2004 {published data only}

Hedge A, Ray EJ. Effect of an electronic height‐adjustable work surface on computer worker musculoskeletal discomfort and productivity. Proceedings of Human Factors & Ergonomic Society, 48th Annual Meeting 2004. SAGE publications, 2004. CENTRAL

Irvine 2011 {published data only}

Irvine AB, Philips L, Seeley J, Wyant S, Duncan S, Moore RW. Get moving: a web site that increases physical activity of sedentary employees. American Journal of Health Promotion 2011;25(3):199‐206. CENTRAL

Jancey 2016 {published data only}

Jancey JM, McGann S, Creagh R, Blackford KD, Howat P, Tye M. Workplace building design and office‐based workers' activity: a study of a natural experiment. Australian & New Zealand Journal of Public Health 2016;40(1):78‐82. CENTRAL

John 2011 {published data only}

John D, Thompson DL, Raynor H, Bielak K, Rider B, Bassett DR. Treadmill workstations: a worksite physical activity intervention in overweight and obese office workers. Journal of Physical Activity and Health 2011;8(8):1034‐43. CENTRAL

Jones 2017 {published data only}

Jones CA. Examining the efficacy and feasibility of digital activity monitors and shared active desks to reduce employee sedentary behavior. Dissertation Abstracts International: Section B: The Sciences and Engineering 2017;77:11‐B(E). CENTRAL

Júdice 2015 {published data only}

Júdice PB, Hamilton MT, Sardinha LB, Silva AM. Randomized controlled pilot of an intervention to reduce and break‐up overweight/obese adults’ overall sitting‐time. Trials 2015;16(1):490. CENTRAL

Kennedy 2007 {published data only}

Kennedy RA, Boreham CA, Murphy MH, Young IS, Mutrie N. Evaluating the effects of a low volume stair climbing programme on measures of health‐related fitness in sedentary office workers. Journal of Sports Science and Medicine 2007;6(4):448‐54. CENTRAL

Kerr 2016 {published data only}

Kerr J, Takemoto M, Bolling K, Atkin A, Carlson J, Rosenberg D, et al. Two‐arm randomized pilot intervention trial to decrease sitting time and increase sit‐to‐stand transitions in working and non‐working older adults. Plos one 2016;11(1):e0145427. CENTRAL

Koepp 2013 {published data only}

Koepp GA, Manohar CU, McCrady‐Spitzer SK, Ben‐Ner A, Hamann DJ, Runge CF, et al. Treadmill desks: a 1‐year prospective trial. Obesity (Silver Spring) 2013;21(4):705‐11. CENTRAL

Lara 2008 {published data only}

Lara A, Yancey AK, Tapia‐Conye R, Flores Y, Kuri‐Morales P, Mistry R, et al. Pausa para tu Salud: reduction of weight and waistlines by integrating exercise breaks into workplace organizational routine. Preventing Chronic DiseaseEpub 2008; Vol. 5, issue 1:A12. CENTRAL

Liu 2016 {published data only}

Liu Y. Supporting working time interruption management through persuasive design. Dissertation Abstracts International: Section B: The Sciences and Engineering 2016;77:3‐B(E). CENTRAL

Maeda 2014 {published data only}

Maeda H, Quartiroli A, Vos PW, Carr LJ, Mahar MT. Feasibility of retrofitting a university library with active workstations to reduce sedentary behavior. American Journal of Preventive Medicine 2014;46(5):525‐8. CENTRAL

Mahmud 2015 {published data only}

Mahmud N, Kenny DT, Md Zein R, Hassan SN. The effects of office ergonomic training on musculoskeletal complaints, sickness absence, and psychological well‐being: a cluster randomized control trial. Asia‐Pacific Journal of Public Health 2015;27(2):NP1652‐68. CENTRAL

Mainsbridge 2014 {published data only}

Mainsbridge CP, Cooley PD, Fraser SP, Pedersen SJ. The effect of an e‐health intervention designed to reduce prolonged occupational sitting on mean arterial pressure. Journal of Occupational and Environmental Medicine 2014;56(11):1189‐94. CENTRAL

Mair 2014 {published data only}

Mair JL, Boreham CA, Ditroilo M, McKeown D, Lowery MM, Caulfield B, et al. Benefits of a worksite or home‐based bench stepping intervention for sedentary middle‐aged adults ‐ a pilot study. Clinical Physiology and Functional Imaging 2014;34(1):10‐7. CENTRAL

Marshall 2003 {published data only}

Marshall AL, Leslie ER, Bauman AE, Marcus BH, Owen N. Print versus web site physical activity programs: a randomised trial. American Journal of Preventive Medicine 2003;25(2):88‐94. CENTRAL

McAlpine 2007 {published data only}

McAlpine DA, Manohar CU, McCrady SK, Hensrud D, Levine JA. An office‐place stepping device to promote workplace physical activity. British Journal of Sports Medicine 2007;41(12):903‐7. CENTRAL

Miyachi 2015 {published data only}

Miyachi M, Kurita S, Tripette J, Takahara R, Yagi Y, Murakami H. Installation of a stationary high desk in the workplace: effect of a 6‐week intervention on physical activity. BMC Public Health 2015;15:368. CENTRAL
UMIN000016731. Installation of a stationary high desk in the workplace: effect of a 6‐week intervention on physical activity. UMIN‐CTR Clinical Trial (accessed 3 June 2015). CENTRAL

NCT01221363 {published data only}

NCT01221363. Reduction of sitting time ‐ a randomised controlled intervention study. http://clinicaltrials.gov/ct2/show/NCT01221363 (accessed 15 March 2014). CENTRAL

Ognibene 2016 {published data only}

Ognibene GT, Torres W, von Eyben R, Horst KC. Impact of a sit‐stand workstation on chronic low back pain: results of a randomized trial. Journal of Occupational and Environmental Medicine 2016;58(3):287‐93. CENTRAL

Opdenacker 2008 {published data only}

Opdenacker J, Boen F. Effectiveness of face‐to‐face versus telephone support in increasing physical activity and mental health among university employees. Journal of Physical Activity and Health 2008;5(6):830‐43. CENTRAL

Ouyang 2015 {published data only}

Ouyang P, Stewart KJ, Bedra ME, York S, Valdiviezo C, Finkelstein J. Text messaging to reduce inactivity using real‐time step count monitoring in sedentary overweight females. Circulation 2015;131:AMP10. CENTRAL

Parry S 2013 {published data only}

ACTRN12612000743864. Can a participatory workplace intervention improve sedentary behaviour and physical activity in office workers?. http://www.anzctr.org.au/ACTRN12612000743864.aspx (accessed 14 March 2014). CENTRAL
Parry S, Straker L, Gilson ND, Smith AJ. Participatory workplace interventions can reduce sedentary time for office workers ‐ a randomised controlled trial. PLoS One 2013;8(11):e78957. CENTRAL

Pilcher 2017 {published data only}

Pilcher JJ, Morris DM, Bryant SA, Merritt PA, Feigl HB. Decreasing sedentary behavior: effects on academic performance, meta‐cognition, and sleep. Frontiers in Neuroscience 2017;11(101478481):219. CENTRAL

Poirier 2016 {published data only}

Poirier J, Bennett WL, Jerome GJ, Shah NG, Lazo M, Yeh HC, et al. Effectiveness of an activity tracker‐ and internet‐based adaptive walking program for adults: a randomized controlled trial. Journal of Medical Internet Research 2016;18(2):e34. CENTRAL

Pronk 2012 {published data only}

Pronk NP, Katz AS, Lowry M, Payfer JR. Reducing occupational sitting time and improving worker health: the Take‐a‐Stand Project. Preventing Chronic Disease 2012;9:e154. CENTRAL

Roossien 2017 {published data only}

Roossien CC, Stegenga J, Hodselmans AP, Spook SM, Koolhaas W, Brouwer S, et al. Can a smart chair improve the sitting behavior of office workers?. Applied Ergonomics 2017;65:355‐61. CENTRAL

Schwartz 2016 {published data only}

Schwartz B, Kapellusch JM, Schrempf A, Probst K, Haller M, Baca A. Effect of a novel two‐desk sit‐to‐stand workplace (ACTIVE OFFICE) on sitting time, performance and physiological parameters: protocol for a randomized control trial. BMC Public Health 2016;16(100968652):578. CENTRAL

Slootmaker 2009 {published data only}

Slootmaker SM, Chinapaw MJ, Schuit AJ, Seidell JC, Van Mechelen W. Feasibility and effectiveness of online physical activity advice based on a personal activity monitor: randomised controlled trial. Journal of Medical Internet Research 2009;11(3):e27. CENTRAL

Sternfeld 2009 {published data only}

Sternfeld B, Block C, Quesenberry CP, Block TJ, Husson G, Norris JC, et al. Improving diet and physical activity with ALIVE: a worksite randomised trial. American Journal of Preventive Medicine 2009;36(6):475‐83. CENTRAL

Straker 2013 {published data only}

Straker L, Abbott R, Heiden M, Mathiassen S, Toomingas A. Sit‐stand desks and sedentary behavior in Swedish call centre workers. Journal of Science and Medicine in Sport 2012;15:S194. CENTRAL
Straker L, Abbott RA, Heiden M, Mathiassen SE, Toomingas A. Sit‐stand desks in call centres: associations of use and ergonomics awareness with sedentary behavior. Applied Ergonomics 2013;44(4):517‐22. CENTRAL

Taylor 2016 {published data only}

Taylor WC, Paxton RJ, Shegog R, Coan SP, Dubin A, Page T, et al. Impact of booster breaks and computer prompts on physical activity and sedentary behavior among desk‐based workers: a cluster‐randomized controlled trial. Preventing Chronic Disease 2016;13(101205018):E155. CENTRAL

Thogersen‐Ntoumani 2013 {published data only}

NCT01150084. Step by Step: a feasibility study of the promotion of lunchtime walking to increase physical activity and improve mental well‐being in sedentary employees. http://clinicaltrials.gov/ct2/show/NCT01150084 (accessed 15 March 2014). CENTRAL
Thogersen‐Ntoumani C, Loughren E, Duda J, Fox KR. "Step by Step": a feasibility study of a lunchtime walking intervention designed to increase walking, improve mental well‐being and work performance in sedentary employees: rationale and study design. BMC Public Health 2010;10:578. CENTRAL
Thogersen‐Ntoumani C, Loughren E, Duda J, Fox KR. Step by Step: the feasibility of a 16‐week workplace lunchtime walking intervention for physically inactive employees. Journal of Physical Activity And Health 2013;10:Epub ahead of print. CENTRAL
Thogersen‐Ntoumani C, Loughren EA, Kinnafick F‐E, Taylor IM, Duda JL, Fox KR. Changes in work affect in response to lunchtime walking in previously physically inactive employees: a randomized trial. Scandinavian Journal of Medicine & Science in Sports 2015;25(6):778‐87. CENTRAL

Thompson 2014 {published data only}

Thompson WG, Koepp GA, Levine JA. Increasing physician activity with treadmill desks. Work2014; Vol. 48, issue 1:47‐51. CENTRAL

Thorp 2015 {published data only}

Thorp AA, Kingwell BA, English C, Hammond L, Sethi P, Owen N. Alternating sitting and standing increases the workplace energy expenditure of overweight adults. Journal of Physical Activity and Health 2015;8:[Epub ahead of print]. CENTRAL

Torbeyns 2016 {published data only}

Torbeyns T, de Geus B, Bailey S, De Pauw K, Decroix L, Van Cutsem J, et al. Bike desks in the office: Physical health, cognitive function, work engagement, and work performance. Journal of Occupational & Environmental Medicine 2016;58(12):1257‐63. CENTRAL

Torbeyns 2017 {published data only}

Torbeyns T, De Geus B, Bailey S, Decroix L, Meeusen R. The potential of bike desks to reduce sedentary time in the office: a mixed‐method study. Public Health 2017;144:16‐22. CENTRAL

Tucker 2016 {published data only}

Tucker S, Farrington M, Lanningham‐Foster LM, Clark MK, Dawson C, Quinn GJ. Worksite physical activity intervention for ambulatory clinic nursing staff. Workplace Health & Safety 2016;64(7):313‐25. CENTRAL

vanNassau 2015 {published data only}

van Nassau F, Chau JY, Lakerveld J, Bauman AE, van der Ploeg HP. Validity and responsiveness of four measures of occupational sitting and standing. The International Journal of Behavioral Nutrition and Physical Activity 2015;12:144. CENTRAL

Wirick 2016 {published data only}

Wirick SE. The promotion of regular exercise behavior among sedentary emerging adults based on social cognitive theory. Dissertation Abstracts International: Section B: The Sciences and Engineering 2016;76:7‐B(E). CENTRAL

Yancey 2004 {published data only}

Yancey AK, McCarthy WJ, Taylor WC, Merlo A, Gewa C, Weber MD, et al. The Los Angeles Lift Off: a sociocultural environmental change intervention to integrate physical activity into the workplace. Preventive Medicine 2004;38(6):848‐56. CENTRAL

Østerås 2005 {published data only}

Østerås H, Sigbjørn H. The effectiveness of a pragmatic worksite physical activity program on maximal oxygen consumption and the physical activity level in healthy people. Journal of Bodywork and Movement Therapies 2006;10(1):51‐7. CENTRAL

References to studies awaiting assessment

Carpenter 2015 {published data only}

Carpenter K, Feltes L, Vuing B, Kalbes A, Koepp G, Dutta N, et al. Effect of sit‐stand workstations on metabolic risk in sedentary workers: a randomized controlled trial. The Journal of the Federation of American societies for Experimental Biology 2015;29:supplement 1. CENTRAL

Dutta 2013 {published data only}

Dutta N, Koepp G, Schmitz C, Stovitz SD, Levine JA, Pereira MA. Impact of adjustable sit‐stand workstations on physical activity in sedentary office workers. Diabetes 2013;62:A186. CENTRAL

Kirk 2012 {published data only}

Kirk A, Fitzsimons C, Murphy M, Mutrie N. Effect of a person centred consultation intervention to reduce the sedentary behaviour of working Scottish adults. Journal of Science and Medicine in Sport 2012;15:S314. CENTRAL

NCT02932787 {published data only}

NCT02932787. Effects of installing height‐adjustable workstations on office workers workplace sitting time and productivity. https://clinicaltrials.gov/show/NCT02932787 (accessed 12 September 2017). CENTRAL

ACTRN12612001290886 {published data only}

ACTRN12612001290886. The effectiveness of the 10,000 Steps workplace challenge in increasing health outcomes for employees at Rockhampton Regional Council. http://www.anzctr.org.au/ACTRN12612001290886.aspx (accessed 15 March 2014). CENTRAL

ACTRN12614000252617 {published data only}

ACTRN12614000252617. Comparison of organisational support vs. organisational plus technology support for reducing prolonged sitting in the office workplace. http://www.anzctr.org.au/ACTRN12614000252617.aspx (accessed 15 March 2014). CENTRAL

Bergman 2015 {published data only}

Bergman F, Boraxbekk CJ, Wennberg P, Sörlin A Olsson T. Increasing physical activity in office workers – the Inphact Treadmill study; a study protocol for a 13‐month randomized controlled trial of treadmill workstations. BMC Public Health 2015;15(1):632. CENTRAL
NCT01997970. NEAT ‐ Prevention and treatment of overweight and obesity. (InphactUm). https://clinicaltrials.gov/ct2/show/NCT01997970 (accessed 3 June 2015). CENTRAL

Buman 2017 {published data only}

Buman MP, Mullane SL, Toledo MJ, Rydell SA, Gaesser GA, Crespo NC, et al. An intervention to reduce sitting and increase light‐intensity physical activity at work: design and rationale of the 'Stand & Move at Work' group randomized trial. Contemporary Clinical Trials 2017;53:11‐9. CENTRAL
NCT02566317. Stand & Move at Work. https://clinicaltrials.gov/ct2/show/NCT02566317 (accessed 12 September 2017). CENTRAL

Dunstan 2014 {published data only}

ACTRN12611000742976. Stand Up Victoria: a trial to determine whether environmental modification and behavioural counselling can lead to reductions in workplace sitting time in office workers. http://www.anzctr.org.au/ACTRN12611000742976.aspx (accessed 15 March 2014). CENTRAL
Dunstan DW, Wiesner G, Eakin EG, Neuhaus M, Owen N, LaMontagne AD, et al. Reducing office workers' sitting time: rationale and study design for the Stand Up Victoria cluster randomised trial. BMC Public Health 2013;13:1057. CENTRAL
Neuhaus M, Healy GN, Fjeldsoe BS, Lawler S, Owen N, Dunstan DW, et al. Iterative development of Stand Up Australia: a multi‐component intervention to reduce workplace sitting. International Journal of Behavioral Nutrition and Physical Activity 2014;11:21. CENTRAL

Finkelstein 2015 {published data only}

Finkelstein EA, Sahasranaman A, John G, Haaland, BA, Bilger M, Sloan RA, et al. Design and baseline characteristics of participants in the TRial of Economic Incentives to Promote Physical Activity (TRIPPA): a randomized controlled trial of a six month pedometer program with financial incentives. Contemporary Clinical Trials 2015;41:238‐47. CENTRAL
NCT01855776. A randomized trial of economic incentives to promote walking among full time employees. https://clinicaltrials.gov/ct2/show/NCT01855776 (accessed 12 September 2017). CENTRAL

Finni 2011 {published data only}

Finni T, Saakslahti A, Laukkanen A, Pesola A, Sipilä S. A family based tailored counselling to increase non‐exercise physical activity in adults with a sedentary job and physical activity in their young children: design and methods of a year‐long randomised controlled trial. BMC Public Health2011; Vol. 11. CENTRAL
ISRCTN28668090. Actions to reduce sedentary time in parents and their young children. http://www.isrctn.com/ISRCTN28668090 (accessed 15 March 2014). CENTRAL

Hall 2015 {published data only}

Hall J, Mansfield L, Kay T, McConnell AK. The effect of a sit‐stand workstation intervention on daily sitting, standing and physical activity: protocol for a12 month workplace randomised control trial. BMC Public Health 2015;15:152. CENTRAL
NCT02172599. Take a stand for workplace health: A sit‐stand workstation project evaluation. https://clinicaltrials.gov/ct2/show/NCT02172599?term=workplace+and+sitting&rank=1 (accessed 3 June 2015). CENTRAL

ISRCTN25767399 {published data only}

ISRCTN25767399. Impact of Booster Breaks on physical activity among sedentary employees: a cluster randomized controlled trial. http://apps.who.int/trialsearch/Trial2.aspx?TrialID=ISRCTN25767399 (accessed 3 June 2015). CENTRAL

Mackey 2011 {published data only}

ACTRN12610000301066. Walking to Wellness in an ageing sedentary university community. http://www.anzctr.org.au/ACTRN12610000301066.aspx (accessed 15 March 2014). CENTRAL
Mackey M, Bohle P, Taylor P, Di Biase T, McLoughlin C, Purnell K. 'Walking to wellness' in an ageing sedentary university community‐a randomised controlled feasibility study. Physiotherapy. 2011; Vol. 97:eS733‐eS4. CENTRAL
Mackey MG, Bohle P, Taylor P, Di Biase T, McLoughlin C, Purnell K. Walking to wellness in an ageing sedentary university community: design, method and protocol. Contemporary Clinical Trials 2011;32(2):273‐9. CENTRAL

Mantzari 2016 {published data only}

ISRCTN44827407. Does using sit‐stand desks at work affect how many calories people burn and how much time they spend sitting over the entire day? A feasibility study. http://www.isrctn.com/ISRCTN44827407 (accessed 12 September 2017). CENTRAL
Mantzari E, Wijndaele K, Brage S, Griffin SJ, Marteau TM. Impact of sit‐stand desks at work on energy expenditure and sedentary time: protocol for a feasibility study. Pilot and Feasibility Studies 2016;2(30):eCollection. CENTRAL

Martin‐Borras 2014 {published data only}

Borras CM, Garriga MG, Martinez E, Cantera CM, Puigdoménech E, Solà M, et al. Effectiveness of a primary care‐based intervention to reduce sitting time in overweight and obese patients (SEDESTACTIV): a randomised controlled trial; rationale and study design. BMC Public Health2014; Vol. 14. CENTRAL
NCT01729936. SedestActiv Project: intervention to reduce diary hours of sitting time in overweight and obese patients. http://clinicaltrials.gov/ct2/show/NCT01729936 (accessed 15 March 2014). CENTRAL

NCT01787643 {published data only}

NCT01787643. Standing behavior after installation of height‐adjustable desks. http://clinicaltrials.gov/ct2/show/NCT01787643 (accessed 15 March 2014). CENTRAL

NCT01846013 {published data only}

NCT01846013. Increasing workplace physical activity in sedentary office workers. http://clinicaltrials.gov/ct2/show/NCT01846013 (accessed 15 March 2014). CENTRAL

NCT02376504 {published data only}

NCT02376504. Modifying the workplace to decrease sedentary behavior and improve health. https://clinicaltrials.gov/ct2/show/NCT02376504?term=workplace+and+sitting&rank=3 (accessed 3 June 2015). CENTRAL

NCT02609282 {published data only}

NCT02609282. The impact of hourly prompts on reducing prolonged sitting at work. https://clinicaltrials.gov/show/NCT02609282 (accessed 12 September 2017). CENTRAL

NCT02785640 {published data only}

NCT02785640. A study to assess the impact of a multicomponent intervention to reduce prolonged sitting in the workplace. https://clinicaltrials.gov/show/NCT02785640 (accessed 12 September 2017). CENTRAL

NCT03236597 {published data only}

NCT03236597. Assessing the effects of treadmill and sit‐to‐stand desks on light physical activity, sitting time, and cardio‐metabolic risk. https://clinicaltrials.gov/show/NCT03236597 (accessed 12 September 2017). CENTRAL

O’Connell 2015 {published data only}

ISRCTN10967042. SMArT Work: Stand More AT Work. http://www.isrctn.com/ISRCTN10967042 (accessed 25 December 2015). CENTRAL
O’Connell SE, Jackson BR, Edwardson CL, Yates T, Biddle SJH, Davies MJ, et al. Providing NHS staff with height‐adjustable workstations and behaviour change strategies to reduce workplace sitting time:protocol for the Stand More AT (SMArT)Work cluster randomised controlled trial. BMC Public Health 2015;15:1219. CENTRAL

Radas 2013 {published data only}

ACTRN12613000366752. Reducing sedentary behaviour in office workers. https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=363960 (accessed 15 March 2014). CENTRAL
Radas A, Mackey M, Leaver A, Bouvier AL, Chau JY, Shirley D, et al. Evaluation of ergonomic and education interventions to reduce occupational sitting in office‐based university workers: study protocol for a randomised controlled trial. Trials2013; Vol. 14. CENTRAL

Van Hoye 2012 {published data only}

Van Hoye K, Boen F, Lefevre J. The effects of physical activity feedback on behavior and awareness in employees: study protocol for a randomised controlled trial. International Journal of Telemedicine and Applications 2012;2012:10. CENTRAL

Aadahl 2003

Aadahl M, Jorgensen T. Validation of a new self‐report instrument for measuring physical activity. Medicine and Science in Sports and Exercise 2003;35(7):1196‐202.

AFOEM 2014

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Ainsworth BE, Haskell WL, Whitt MC, Irwin ML, Swartz AM, Strath SJ, et al. Compendium of physical activities: an update of activity codes and MET intensities. Medicine and Science in Sports and Exercise 2000;32(9 Suppl):S498‐504.

Ainsworth 2011

Ainsworth BE, Haskell WL, Herrmann SD, Meckes N, Bassett DRJ, Tudor‐Locke C, et al. 2011 Compendium of physical activities: a second update of codes and MET values. Medicine and Science in Sports and Exercise 2011;43(8):1575‐81.

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Andersen JH, Haahr JP, Frost P. Risk factors for more severe regional musculoskeletal symptoms: a two‐year prospective study of a general working population. Arthritis and rheumatism 2007;56(4):1355‐64.

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Atkinson J, Haynes K. Standing meeting rooms – exploring enablers and barriers of interventions to reduce sitting time in the workplace. Australian and New Zealand Journal of Public Health June 2014;38(3):291‐2.

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Australian Government, Department of Health and Aging. Make your Move – sit less. Be active for life! Australia's physical activity and sedentary behaviour guidelines. Canberra: Commonwealth of Australia. http://www.health.gov.au/internet/main/publishing.nsf/content/health‐pubhlth‐strateg‐phys‐act‐guidelines#npa052014.

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Bailey DP, Locke CD. Breaking up prolonged sitting with light‐intensity walking improves postprandial glycemia, but breaking up sitting with standing does not. Journal of Science and Medicine in Sport 2015;18(3):294‐8.

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Bey L, Hamilton MT. Suppression of skeletal muscle lipoprotein lipase activity during physical inactivity: a molecular reason to maintain daily low‐intensity activity. The Journal of Physiology 2003;1(551):673‐82.

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Botter J, Ellegast RP, Burford EM, Weber B, Könemann R, Commissaris DA. Comparison of the postural and physiological effects of two dynamic workstations to conventional sitting and standing workstations. Ergonomics 2015;(Epub ahead of print):1‐15.

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Buckley JP, Hedge A, Yates T, Copeland RJ, Loosemore M, Hamer M, et al. The sedentary office: an expert statement on the growing case for change towards better health and productivity. British Journal of Sports Medicine 2015;49(21):1357‐62.

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Campbell MK, Mollison J, Grimshaw JM. Cluster trials in implementation research: estimation of intracluster correlation coefficients and sample size. Statistics in Medicine 2001;20(3):391‐9.

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Chaua JY, Grunseita A, Midthjellb K, Holmen J, Holmenabb TL, Baumana AE, et al. Cross‐sectional associations of total sitting and leisure screen time with cardio metabolic risk in adults. Results from the HUNT study, Norway. Journal of Science and Medicine in Sport 2014;17:78‐84.

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Coenen P, Healy GN, Winkler E, Dunstan DW, Straker L. Musucloskeletal pain is a barrier for sedentary behavior interventions. Proceedings 19th triennial congress of the IEA. Melbourne, 2015.

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Commissaris DACM, Douwes M, Schoenmaker N, de Korte EM. Recommendations for sufficient physical activity at work. 2007. http://www.nordiskergonomi.org/nes2007/CD_NES_2007/papers/A79_Commissaris.pdf. Elsevier, Oxford, (accessed 25 November 2013).

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Commissaris DACM, Konemann R, Mastrigt SH, Burford EM, Botter J, Douwes M, et al. Effects of a standing and three dynamic workstations on computer task performance and cognitive function tests. Applied Ergonomics 2014;45:1570‐8.

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Commissaris DACM, Huysmans MA, Mathiassen SE, Srinivasan D, Koppes LLJ, Hendriksen IJM. Interventions to reduce sedentary behavior and increase physical activity during productive work: a systematic review. Scandinavian Journal of Work Environment and Health 2016;42:181‐91.

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Cooley D, Pedersen S, Mainsbridge C. Assessment of the impact of a workplace intervention to reduce prolonged occupational sitting time. Qualitative Health Research2014; Vol. 24:90‐101.

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Craft LL, Zderic TW, Gapstur SM, Vaniterson EH, Thomas DM, Siddique J, et al. Evidence that women meeting physical activity guidelines do not sit less: an observational inclinometry study. International Journal of Behavioral Nutrition and Physical Activity 2012;9:122.

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Craig CL, Brownson RC, Cragg SE, Dunn AL. Exploring the effect of the environment on physical activity: a study examining walking to work. American Journal of Preventive Medicine 2002;23(2 Suppl):36‐43.

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Department of Health. Start active, stay active: a report on physical activity for health from the Four Home Countries' Chief Medical Officers. London, UK: Department of Health. https://www.gov.uk/government/publications/start‐active‐stay‐active‐a‐report‐on‐physical‐activity‐from‐the‐four‐home‐countries‐chief‐medical‐officers2011.

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Characteristics of studies

Characteristics of included studies [ordered by study ID]

Alkhajah 2012

Methods

Non‐random allocation by clusters: CBA

Single‐blind

Study duration: 3 months

Dropout: 9%

Location: Australia

Recruitment: control group participants were recruited from locations separated from the intervention group participants by at least 1 building level

Participants

Population: employees in public health research centres within 2 academic institutions, aged 20‐65 years

Intervention group: 18 participants

Control group: 12 participants

Demographics:

BMI: intervention group 22.6 (SD 2.6) kg/m², control group 21.5 (SD 2.6) kg/m²

Interventions

Duration: 3 months

Intervention: sit‐stand desk

Control: sit‐desk

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Changes in sitting/standing/stepping time (minutes/8‐hour workday) measured at 1 week and 3 months. Transitions in positions measured by activPAL3 accelerometer‐inclinometer and a self‐administered questionnaire

  • Weight (kg), waist circumference (cm), hip circumference (cm), fat free mass (kg), fat mass (kg), fasting blood lipids (Total cholesterol/HDL/Triglycerides) (mmol/L) and glucose (mmol/L) at 1 week and 3 months

  • Self‐reported health‐ and work‐related outcomes

    • Musculoskeletal symptoms by anatomical regions

    • Other health symptoms: eye strain, headaches, digestion problems, trouble walking, trouble sleeping, fatigue (scale 1‐5)

    • Work‐related outcomes: ≥ 1 day off sick (last 3 months), work performance (scale 1‐10)

Notes

This study was funded by a University of Queensland Major Equipment and Infrastructure grant. Alkhajah was supported by a United Arab Emirates Ministry of Higher Education and Scientifıc Research Scholarship; Reeves was supported by a National Health and Medical Research Council (NHMRC) Early Career Fellowship; Eakin was supported by an NHMRC Senior Research Fellowship; Owen was supported by an NHMRC Senior Principal Research Fellowship; and Healy was supported by an NHMRC Early Career Fellowship. Authors reported no financial disclosures.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

Randomisation was not done as participants in intervention and control groups were selected from different building locations.

Allocation concealment (selection bias)

High risk

Intervention and control groups were selected from two separate locations. However no information on allocation concealment.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

The intervention group had sit‐stand desks installed at their workplace and received verbal instruction on their use, as well as written instructions on the correct ergonomic posture for both sitting and standing and the importance of regular postural change throughout the day. The control group had no change in desks and participants were advised to maintain usual day‐to‐day activity. The participants were probably aware of their allocation. The authors do not report who gave the instructions to the intervention and control groups.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

Virtually no attrition: only one participant was missing from the control group because of a malfunctioning accelerometer‐inclinometer.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the method section were reported. Study protocol was not available.

Baseline comparability/ imbalance

High risk

Baseline data for age and gender were similar. It seems probable that there were baseline imbalances in awareness and physical activity levels between intervention and control groups as participants to the intervention group were selected from an academic institution focused on sedentary behaviour research whereas participants in the control group were never involved in physical activity research.

Validity of outcome measure

Low risk

The accelerometer‐inclinometer is a valid instrument for the measurement of sitting time.

Brakenridge 2016

Methods

Random allocation by clusters

Single‐blind

Study duration: 12 months

Dropout: more than 45% in both groups.

Location: Australia

Recruitment: participants were invited to attend an information session, during which eligibility was confirmed and informed written consent was obtained.

Participants

Population: employees from an international property and infrastructure group, located at two cities: Sydney and Brisbane.

Organisational‐support intervention (ORG) group: 9 teams with 117 employees

ORG + tracker group: 9 teams with 93 employees

Demographics:

Mean age: ORG group: 40.0 (SD 8.0), ORG + tracker group: 37.6 (SD 7.8)

% of males: ORG group 60 %, ORG+ tracker group 47 %

BMI: ORG group 25.0 (SD 3.4) kg/m², ORG + tracker group 24.1 (SD 3.4) kg/m²

Interventions

Duration: 12 months

Organisational‐support intervention (ORG group): information booklet, five fortnightly emails consisting of chosen activity‐promoting tips, comments from participants or managers, images of participants taking part in the ‘Stand Up, Sit Less, Move More’ message and the organisation’s branding.

ORG + tracker group: organisational support combined with activity tracker

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Changes in sitting/standing/stepping time during work hours (minutes/10‐hour workday) and overall hours (minutes/16‐hour) measured at 3 months and 12 months. Transitions in positions measured by activPAL3 accelerometer‐inclinomete

  • Self‐reported health‐ and work‐related outcomes

    • Health‐related outcomes: stress (single item, 1–10 scale; higher scores indicate more stress), physical and mental health quality of life (12 items, 0–100 scale; higher scores indicate better quality of life)

    • Work‐related outcomes (scale 1–10): job performance, job control, work satisfaction

Notes

The authors declared that they have no competing interests.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Randomisation sequence was generated using randomisation website.

Allocation concealment (selection bias)

Low risk

A university staff member not involved in the study randomised

teams by strata (location B/small location A teams/large location A teams) to either Group ORG or Group ORG + tracker.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Neither the research team nor participants were blinded to participants’ randomisation status.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

Missing data were imputed by chained equations.

Selective reporting (reporting bias)

Low risk

All the outcomes mentioned in the protocol were reported.

Baseline comparability/ imbalance

High risk

Group ORG had a higher proportion of males, senior leaders and overweight participants, had fewer managers and reported more lower‐extremity musculoskeletal problems than Group ORG + tracker.

Validity of outcome measure

Low risk

The accelerometer is a valid instrument for the measurement of sitting time.

Carr 2015

Methods

Random allocation

Single‐blind

Study duration: 8 months

Drop out: 10% (five participants were lost to follow‐up and one discontinued the intervention).

Location: USA

Recruitment: participants were recruited via an electronic advertisement on the company’s well‐being website. The advertisement included a link to an online eligibility survey. Research staff contacted interested and eligible employees via telephone to schedule a baseline testing session.

Participants

Population: healthy adults working in full‐time sedentary jobs at a large private company were invited to participate via an electronic advertisement on the company’s well‐being website. They were physically inactive, overweight/obese.

Intervention group: 27 participants

Control group: 27 participants

Demographics:

Mean age: intervention: 45.2 (SD 10.9), control 45 (SD 10.7),

70% participants were females in both intervention and control groups

BMI: intervention 34.5 (SD 6.8) kg/m², control 33 (SD 5.6)kg/m²

Interventions

Duration of intervention: 16 weeks

Intervention: ergonomic workstation intervention; three activity‐promoting emails/week and access to a seated active workstation (elliptical machine, activeLife Trainer).

Control: ergonomic intervention and emails only.

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Occupational sedentary time and physical activity (% workday in light, moderate and vigorous intensity) measured by accelerometer‐inclinometer

  • Cardiometabolic risk factors (weight, fat mass, lean mass, waist circumference, resting systolic and diastolic blood pressure and resting heart rate)

  • Musculoskeletal discomfort (self reported)

  • Work productivity measured by Health and Work Performance Questionnaire

  • Cognitive function measured as self reported time spent concentrating on work

Notes

The second author, Dr Christoph Leonhard, owns propriety rights to the activeLife Trainer. No other financial disclosures were reported by the authors.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

A 1:1 randomisation scheme was generated by the principal investigator using an online random sequence generator.

Allocation concealment (selection bias)

Low risk

Based on the randomisation scheme, participants were provided a sealed envelope indicating their treatment assignment.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

The envelope was provided by a research assistant who was previously unaware of the randomisation schedule, but the participants were not blinded.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

54 of the 60 participants completed all assessments. Five were lost to follow‐up and one discontinued the intervention thus yielding a total attrition of 10%.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the method section were reported.

Baseline comparability/ imbalance

Low risk

Mean age: intervention: 45.2 (10.9), control 45 (10.7), 70% participants were females in both intervention and control groups, BMI: intervention 34.5 (6.8) kg/m², control 33 (5.6)kg/m²

Validity of outcome measure

Low risk

The accelerometer is a valid instrument for the measurement of sitting time.

Chau 2014

Methods

Random allocation with cross‐over and wait‐list control

Participants were allocated randomly by drawing from the ballot four at a time. The first four were allocated to intervention group and next four to control group for four weeks. The remaining participants were assigned to the wait‐list control condition and were placed on the waiting list in seven groups (four to five people per group). After the initial four weeks, the previous control group received the intervention with the next group from the ballot draw serving as their controls. This was repeated until all nine groups had received the intervention.

Unblinded

Study duration: 9 weeks

Dropout: 7%

Location: Australia

Recruitment: project was advertised to staff as part of their workplace wellness program via internal mail, staff meetings and information fliers in the office. Staff members who were interested in participating contacted the research team and received additional project information and an expression of interest form. They could then join the study ballot by returning the expression of interest form.

Participants

Population: staff from a non‐government health agency in New South Wales, Australia

Demographics:

BMI (kg/m²): underweight (< 18.5): 13%, normal range (18.5–24.9): 50%, overweight (25–29.9): 25%, obese (≥ 30): 13%

Interventions

Duration of intervention: 9 weeks

Intervention: sit‐stand desk

Control: no sit‐stand desk

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Changes in self‐reported and objectively assessed time spent sitting, standing and walking/stepping (minutes/day) before and after the use of a sit‐stand desk measured by ActivPALs and self‐report questionnaires.

  • Domain specific sitting (minutes/day) over the whole day, assessed by self‐report.

Notes

This research was supported by funding from Heart Foundation New South Wales, and Australian National Health and Medical Research Council Program Grant (#569940).

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Randomly drawn from a ballot by a researcher in the presence of potential participants and other researchers. Participants were allocated to the intervention group, control group and wait‐list control condition.

Allocation concealment (selection bias)

High risk

Allocation concealment was not possible due to the open plan nature of the study office environment.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Research staff, participants, and assessors were not blinded to group allocation.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

Three participants who were missing age or BMI values were not included in the analyses. Imputing values for these missing covariate values did not influence the effect of the intervention on the adjusted estimates for the outcomes, nor did it change the effects age or BMI had on the outcome.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the methods section were reported. The study protocol was not available.

Baseline comparability/ imbalance

Low risk

Since the trial used a cross‐over design, all the participants would receive the interventions at some point.

Validity of outcome measure

Low risk

The accelerometer is a valid instrument for the measurement of sitting time.

Chau 2016

Methods

Non‐random allocation: CBA

Single‐blind

Study duration: 20 weeks

Dropout: 22%

Location: Australia

Recruitment: the research team gave a presentation about the study to team leaders and managers, who then discussed the study with their staff. Participants joined the study by returning a signed consent form to the researchers.

Participants

Population: customer care (call centre) staff from two teams working at one worksite of a large telecommunications company in Sydney, Australia.

Intervention group: 16 participants

Control group: 15 participants

Demographics:

Mean age: control 35.1 (SD 11.5), intervention 31.0 (SD 10.0)

The intervention group had higher BMI than control group.

Interventions

Duration: 19 weeks

Intervention: sit‐stand desk + email reminders

Control: no sit‐stand desk

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Changes in sitting/standing/walking time (minutes/8‐hour workday) measured at 1 week, 4 weeks and 19 weeks. Transitions in positions measured by activPAL3 accelerometer‐inclinometer and a self‐administered questionnaire

  • Self‐reported perceptions about work, work‐related energy, and feelings at work at baseline, 4, and 19 weeks post‐installation of sit‐stand desks (intervention)

Notes

A co‐author, Amanda Sainsbury has received payment from Eli Lilly, the Pharmacy Guild of Australia, Novo Nordisk, and the Dietitians Association of Australia for seminar presentations at conferences. She is also the author of The Don’t Go Hungry Diet (Bantam, Australia, and New Zealand, 2007) and Don’t Go Hungry For Life (Bantam, Australia, and New Zealand, 2011).

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

Randomisation was not performed.

Allocation concealment (selection bias)

High risk

Allocation was not concealed.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Neither the research team nor participants were blinded.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

Low participant adherence to activity monitor use and device malfunction resulted in high attrition rates.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the method section were reported. Study protocol was not available.

Baseline comparability/ imbalance

Low risk

Both groups were comparable at baseline for age, sex and BMI.

Validity of outcome measure

Low risk

The accelerometer and Occupational Sitting and Physical Activity Questionnaire (OSPAQ) are valid tools for the measurement of sitting time.

Coffeng 2014

Methods

Random allocation by clusters

Single‐blind
Location: Amsterdam, the Netherlands
Recruitment: a top‐down communication approach was used, starting with the management
• An explanatory meeting with team leaders
• Invitation to all employees from the department to participate in the study
• Data on sick leave, salary and the duration of employment was obtained through the Human Resource Management department

Participants

Population description: office employees (18 years or above), working at the Dutch financial service provider

Demographics:

Age in years: group motivational interviewing (GMI) 43.6 (SD 10.3); environmental modification 42.2 (SD 10.5); GMI + environmental modification 38.0 (SD 10.5); no intervention 40.7 (SD 9.2)

Male [n (%)]: GMI 73 (SD 61.9); Environmental modification 60 (SD 62.5); GMI + Environmental modification 51 (SD 55.4); no intervention 65 (SD 61.3)

Interventions

Duration of intervention: environmental modification: 12 months and GMI: 3.5 months

The Be Active & Relax program was evaluated using 4 arms:
• GMI (group motivational interviewing) and environmental modifications (3 clusters 92 employees);

GMI derived from Motivational Interviewing (MI). MI is a counselling style that stimulates behavioural change by focusing on exploring and resolving ambivalence. A group setting has several benefits, e.g. sharing experiences, providing feedback and giving support.
• Environmental modifications (3 clusters; 96 employees): 1) the VIP Coffee Corner Zone – the coffee corner was modified by adding a bar with bar chairs, a large plant and a giant wall poster (a poster visualizing a relaxing environment, e.g. wood, water and mountains); 2) the VIP Open Office Zone – the office was modified by introducing exercise balls and curtains to divide desks in order to reduce background noise; 3) the VIP Meeting Zone – conference rooms were modified by placing a standing table (a table that allows you to stand while working) and a giant wall poster (as before); and 4) the VIP Hall Zone ‐ table tennis tables were placed and lounge chairs were introduced in the hall for informal meetings. In addition, footsteps were placed on the floor in the entrance hall to promote stair walking.
• GMI (7 cluster; 118 employees);
• No intervention or control group (6 cluster; 106 employees)

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Primary outcome: need for recovery

  • Secondary outcomes: daily physical activity, sedentary behaviour at work, detachment and relaxation, exhaustion, absenteeism, work performance, work engagement

Notes

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Randomisation was executed by an independent researcher by using a computer generated list from SPSS.

Allocation concealment (selection bias)

Unclear risk

No information

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Blinding of the participants and intervention providers for the social environmental intervention was impossible.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

Incompleteness of the data is taken into account with the multilevel analysis. Loss to follow‐up at 6 months was considerable (> 20%). However, there were no significant differences at baseline between responders and non‐responders.

Selective reporting (reporting bias)

Low risk

All mentioned outcomes in the study protocol were reported.

Baseline comparability/ imbalance

Low risk

No differences regarding age, gender, education, marital status, ethnicity, working hours, general health, job demands, supervisor support. Males were slightly over‐represented.

Validity of outcome measure

High risk

Validity of the questionnaire used in the study has not been tested.

Danquah 2017

Methods

Random allocation by clusters

Single‐blind

Study duration: 3 months

Dropout:

Location: Denmark

Recruitment: recruited through a press release and an open invitation in an electronic newsletter aimed at practitioners and health workers in municipalities and private workplaces all over Denmark

Participants

Population: practitioners and health workers in municipalities and private workplaces all over Denmark

Intervention group: 173 participants in 10 offices

Control group: 144 participants in 9 offices

Demographics:

Mean age: intervention 46 (SD 10), control 45 (SD 11)

% of females: intervention 61%, control 73%

BMI: intervention group 26 (SD 5.0) kg/m², control group 27 (SD 4.8) kg/m²

Interventions

Duration: 3 months

Intervention: a multi‐component work‐based intervention (ambassadors, environmental changes, lecture, workshop, emails and texts).

Control: no intervention

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Changes in sitting, standing and number of prolonged sitting periods (> 30 min) ‐ minutes/ 8‐hour workday, number of sit‐to‐stand transitions per hour in a workday, leisure sitting time and MVPA in leisure (minutes/8‐hour leisure) measured at 1 and 3 months. Transitions in positions measured by activPAL3 accelerometer‐inclinometer and a self‐administered questionnaire

  • Weight (kg), waist circumference (cm), fat free mass (kg), fat mass (kg), body fat percentage at 3 months

Notes

Funded by Tryg Fonden, Denmark. The funders had no role in study design, data collection or analysis, decision to publish or preparation of the manuscript.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

A senior researcher carried out the randomisation, using random number sequence in Stata

Allocation concealment (selection bias)

Low risk

Randomisation took place before baseline measurements were recorded, but allocation was not disclosed to participants, researchers or data collectors until the baseline assessments had been completed

Blinding of participants and personnel (performance bias)
All outcomes

High risk

The researchers were not blinded at follow‐up.

Blinding of outcome assessment (detection bias)
All outcomes

Low risk

A blinded version of the data was used for data management and analysis.

Incomplete outcome data (attrition bias)
All outcomes

Low risk

Final levels of missing data on primary outcomes were 9% at baseline, 15% at 1‐month follow‐up and 20% at 3‐ months follow‐up. however missing data were imputed by multiple imputations using chained equations.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the study protocol has been reported.

Baseline comparability/ imbalance

Low risk

Both groups were comparable at baseline for age, sex and BMI.

Validity of outcome measure

Low risk

ActiGraph GT3X accelerometer is a valid instrument for assessing physical activity and sedentary behaviour

De Cocker 2016

Methods

Random allocation by clusters

Single‐blind

Study duration: 3 months

Dropout:

Location: Belgium

Recruitment: employees were invited to participate by email

Participants

Population: employees of 2 companies (a university and an environmental agency) in Flanders

Intervention group: tailored group: 78 participants (2 departments), Generic group: 84 participants (2 departments)

Control group: 51 participants (2 departments)

Demographics:

Age in years: tailored 40.5 (SD 8.6), generic 40.7 (SD 9.7), control 39.3 (SD 9.0)

% of males: tailored 32%, generic 27%, control 15%

% of participants with high school/university education: tailored 58%, generic 70%, control 46%

BMI: tailored 24.2 (3.1) kg/m², generic 23.6 (SD 3.5) kg/m², control group 23.7 (SD 3.5) kg/m²

Interventions

Duration: 3 months

Intervention: tailored group: personalised computer‐tailored feedback about sitting time, including tips and suggestions on how to interrupt (taking short standing breaks) and reduce (replacing sitting by periods of standing) sitting, and in the end motivated participants were invited to create an action plan to convert intentions into specific actions.

Generic group: generic information on the importance of reducing and interrupting sitting

Control: usual lifestyle

Outcomes

Outcome name, measurement time/tool (units of measurement)

Self‐reported changes in sitting (total sitting, sitting at work, domains of leisure sitting) measured at 3 months

Notes

The first author is supported by the Research Foundation Flanders (FWO) (postdoctoral research fellowship: FWO11/PDO/097). Authors declared no conflict of interest.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Unclear risk

Not reported

Allocation concealment (selection bias)

Unclear risk

Not reported

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

Not reported

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

More than 10% participants were lost to follow‐up in each comparison groups.

Selective reporting (reporting bias)

High risk

Not every outcome mentioned in the study protocol has been reported.

Baseline comparability/ imbalance

Low risk

The comparison groups did not differ in sociodemographic, work‐related, and health‐related variables.

Validity of outcome measure

Low risk

The WSQ has acceptable reliability (interclass correlation coefficient = .63) and validity against objectively accelerometer‐measured sitting time (r = .34 to r = .45).

Donath 2015

Methods

Random allocation by minimization

Single‐blind

Study duration: 12 weeks

Drop out: 8%

Location: Switzerland

Participants

Population: staff from the confederate Swiss health insurance company EGK

Intervention: 15 participants

Control: 16 participants

Demographics:

Age: intervention: 45 (SD 12), control: 40 (SD10)

Sex (m/f): intervention 4/11, control 4/12

BMI (kg/m²): Intervention: 23.7 (SD 3.7), control: 24.7 (SD 5)

Interventions

Duration of intervention: 12 weeks

Intervention: computer prompt + information

Control: information only

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Sitting and standing time (hours/week) at 6 and 12 weeks of intervention measured by using the ActiGraph wGT3X‐BT

  • Test d2 of Brickenkamp (paper and pencil test used to examine attention and concentration processes)

  • Neuromuscular outcomes (strength‐endurance and balance outcome).

Notes

Authors reported no conflict of interest

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Group assignment was randomly conducted according to the minimization method: age, gender, BMI, physical activity and working time served as strata criteria in order to minimize group differences in demographical variables.

Allocation concealment (selection bias)

Unclear risk

No information

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Testing personnel were blinded to group allocation. Participants were not blinded.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

3 participants in the control group and 4 participants in the intervention group withdrew due to job changes and illness (8% of participants). They were not included in the analysis (i.e. no intention‐to‐treat analysis).

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the method section were reported. Study protocol was not available.

Baseline comparability/ imbalance

Low risk

Group differences were minimized.

Validity of outcome measure

Low risk

The accelerometer is a valid instrument for the measurement of sitting time.

Dutta 2014

Methods

Random allocation with cross‐over

Unblinded

Study duration: 10 weeks

Dropout: 1231 working hours data were missing

Location: USA

Recruitment: a word‐of‐mouth search was performed for finding interested companies to host the study and Caldrea Inc. volunteered. A recruitment presentation was made at an all‐employee meeting (n ˜ 50) and was followed a few days later by enrolment interviews.

Participants

Population: employees of Caldrea Inc. company, USA

Demographics: average age: 40.4 years; out of 28 participants, 19 were female

Interventions

Duration of intervention: 4 weeks

Intervention: sit‐stand desk

Three different models of desks were used: Workfit‐S, a setup that attaches to the front of one’s existing desk that can hold the computer monitor, keyboard and mouse; Workfit‐A, a setup that is identical to Workfit‐S but attaches to the back of one’s existing desk; and Workfit‐D, a whole desk that is easily moved up and down. The Workfit‐A and S also came with an added work‐surface and all three types of desks came with anti‐fatigue floor mats for comfort during standing.

Control: no sit‐stand desk

Outcomes

Outcome name, measurement time/tool (units of measurement)

Sitting time, standing time, and light activity at work self‐reported and objectively assessed with accelerometer‐inclinometer

Self‐reported energy and relaxation levels

Notes

James A. Levine has patents in accelerometer algorithms with Gruve Technologies Inc. but he did not access or analyse the raw the data from the Gruve device.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Participants were randomly assigned to receive the intervention during period 1 or period 2, using a 1:1 allocation in 1 block of 35, using Microsoft Excel 2007.

Allocation concealment (selection bias)

High risk

Allocation concealment was not possible due to the nature of the intervention.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Blinding of participants and personnel was not possible due to the nature of intervention.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

If we assume a person works for 40 hours per week, then for 28 participants the working hours will be 8960 hours for 8 weeks (4 weeks intervention and 4 weeks control period). However the study reported only 7,729 working hours based on accelerometer data.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the methods section were reported. The study protocol was not available.

Baseline comparability/ imbalance

Low risk

There were no significant differences in age or BMI between interventions and control groups. Most of the participants were female.

Validity of outcome measure

Low risk

The accelerometer is a valid instrument for the measurement of sitting time.

Ellegast 2012

Methods

Random allocation

Unblinded

Study duration: 12 weeks

No dropouts

Location: Germany

Only part of the study was presented as all the data have not been analysed.

Participants

Population: desk‐based employees at VDU workplaces

Demographics: mean age (years): 40.7 (range 24 to 58), control 42.1 (range 25 to 61)

4 female participants in both intervention and control groups

Mean BMI: 26.3 (SD 3.2) kg/m²

Interventions

Duration of intervention: 12 weeks

Intervention

  • A recreational intervention consisting of sit‐stand workplaces: 1) electrically adjustable (68cm to 118cm) writing desk and PC‐table; 2) height and angle adjustable lecterns in that were also movable in the room combined with a foot stand; 3) stand tables during breaks; 4) table tennis in the cellar; 5) individual changes to the VDU station plus oral and written instructions to use printers further away and to use stairs.

  • A behavioural intervention: 1) midday gymnastics (11.45am‐12.00 am) with relaxation, stretch, power and co‐ordination exercises; participants were instructed to participate every day; 2) action: cycle to work: every day participants could indicate if they cycled to work and be eligible for a prize; 3) afternoon (lunch?) walk; 4) company sports offer; 5) bonus point system: for every activity performed the participants got points that could be exchanged for small extras: apples, muesli bar etc.; 6) AiperMotion: participants wore an activity monitoring device that they could read anytime; 7) step barometer; every week the results of the step counter in the AiperMotion device was published as an average over the week for every participant in one chart.

Control: usual office work

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Assessment of physical activity: changes in standing and sitting (min/day), number of steps and energy expenditure

  • Assessment of well‐being and medical check‐up: body mass index, multidimensional mood questionnaire, general medical examination

Notes

This project was initiated and funded by the German Social Accident Insurance (DGUV).

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Following correspondence with the authors, they replied: "Randomization by computer generated list".

Allocation concealment (selection bias)

Low risk

Following correspondence with the authors, they replied: "our secretary, who was not involved in the project, generated the allocation list".

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Following correspondence with the authors, they replied: "The participants were blinded, the personnel was not blinded (they knew according to the subject code, who belongs to the Intervention group and to the Control group)".

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

No attrition

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the method section were reported.

Baseline comparability/ imbalance

Low risk

Participants were recruited from different VDU workplaces. No significant difference in age of participants between intervention and control groups. 4 female participants in both intervention and control groups.

Validity of outcome measure

Low risk

The accelerometer is a valid instrument for the measurement of sitting time.

Evans 2012

Methods

Random allocation: RCT

Single‐blind

Study duration: 10 days

Dropout: 7%

Location: United Kingdom

Recruitment: healthy working adults who could stand unassisted recruited via poster and email

Participants

Population: healthy adults working in an office at Glasgow Caledonian University in Scotland

Intervention group: 14 participants (computer prompts (CP))

Control group: 14 participants (education)

Demographics: CP group (mean age 49 (SD 8 years) were older than the education group (mean age 39 (SD 10) years), predominantly female (11 in CP group and 11 in education group), worked as administrators (4 in CP group and 3 in education group), researchers (5 in CP group and 7 in education group), lecturers (5 in CP group and 4 in education group)

BMI: CP group 23.7 (SD 3.5) vs. education group 23.6 (SD 2.8)

Interventions

Duration of intervention: 5 days but the participants were followed up for 10 days.

Intervention: CP + information

Control: information only (a short educational talk)

All participants received a short educational talk regarding the health risks of prolonged sitting stating that standing every 30 minutes could be beneficial, and a short information leaflet was also provided. Then participants in the intervention group had a prompting software installed in their personal computer to remind them to take a break for 1 min every 30 minutes.

Outcomes

Outcome name, measurement time/tool (units of measurement)

Assessed with thigh‐mounted accelerometer‐inclinometer

  • Total sitting time (h/day)

  • Number of sitting events (events/day)

  • Number of prolonged sitting events (events/day)

  • Duration of prolonged sitting events (h/day)

Notes

This study was funded by the School of Health, Glasgow Caledonian University and formed the dissertation project for Masters of Rehabilitation Science of Rhian Evans, Henrietta Fawole, and Stephanie Sheriff. No financial support was received from any commercial company. No financial disclosures were reported by the authors of this publication.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Random number generation was used.

Allocation concealment (selection bias)

Low risk

Information on the group assignment was placed into sequentially numbered sealed opaque envelopes. The researcher was involved in opening the envelope immediately after the education.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Both the researcher and participants were aware of the allocation. Awareness of the purpose of the study may have led the education group participants to behave differently during the study, which may have affected the outcomes.

Blinding of outcome assessment (detection bias)
All outcomes

Low risk

Data treatment was conducted by a researcher blinded to the allocation of the participants.

Incomplete outcome data (attrition bias)
All outcomes

Low risk

2 participants were excluded from analyses due to incomplete data: 1 from the CP group and 1 from the education group. As the same proportion of participants were excluded from both groups, the missing data did not have much impact on outcomes.

Selective reporting (reporting bias)

High risk

Not all outcomes mentioned in the study protocol were reported.

Baseline comparability/ imbalance

Low risk

CP group (mean age 49 (SD 8) years) was older than the education group (mean age 39 (SD 10) years), participants worked as administrators (4 in CP group, 3 in education group), researchers (5 in CP group, 7 in education group), or lecturers (5 in CP group, 4 in education group) and were predominantly female (11 in CP group, 11 in education group)

Validity of outcome measure

Low risk

The accelerometer is a valid instrument for the measurement of sitting time.

Gao 2015

Methods

Non‐random allocation

Unblinded

Study duration: 6 months

Dropouts: 49%

Location: University of Jyväskylä, Finland

Recruitment: all faculty employees (n = 170) were invited to fill out a questionnaire between August and September 2012 and again in February 2013.

Participants

Population: healthy adults working in a university setting: researchers, teachers, administrative workers, assistants, professors and technical workers.

Intervention group: 24 participants

Control group: 21 participants

Demographics: mean age: intervention 47.8 (SD 10.8) years, control 39 (SD 8.5) years. 70.8% were females in the intervention group and 81% were females in the control group.

BMI (kg/m²): intervention: 24.8 (SD 3.9), control: 23.3 (SD 3.8)

Interventions

Duration of intervention: 6 months

Intervention: sit‐stand desk

Control: no intervention

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Changes in occupational sedentary time (% of work time spent sitting and standing) measured by self‐reported questionnaire

  • Changes in health outcomes and work ability measured by self‐reported questionnaire

  • Daily usage of the sit–stand function measured by self‐reported questionnaire

Notes

The study was funded by the China Scholarship Council (201206320092).

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

The study did not employ randomisation. Part of the personnel moved to a renovated building with sit‐stand desks.

Allocation concealment (selection bias)

High risk

Allocation was not concealed.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

No blinding

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

The questionnaire was returned by 92 employees at baseline, before working at sit–stand desks, and 61 employees after 6 months. Those who completed the questionnaire only once were excluded, leaving 45 individuals who were included in the analysis. The study lost 49% participants during follow‐up.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the protocol were reported.

Baseline comparability/ imbalance

High risk

In the intervention group participants were older and had more experience of office work. 70.8% were females in the intervention group and 81% were females in the control group. BMI (kg/m²): intervention: 24.8 (3.9), control: 23.3 (3.8)

Validity of outcome measure

High risk

Validity of the questionnaire used in the study has not been tested.

Gilson 2009

Methods

Random allocation

Unblinded

Study duration: 10 weeks

Dropout: 16%

Location: UK, Australia and Spain

Recruitment: participants came from 3 major regional universities in 3 countries, represented by a lead investigator in each university, who had expressed an interest in running an employee intervention at their respective university as part of an evolving, international project.

Participants

Population: white‐collar (i.e. professional, managerial, or administrative) university staff from the UK (n = 64), Australia (n = 70) and Spain (n = 80)

Intervention groups:

  • route walking group 60 participants;

  • incidental walking group 59 participants.

Control group: 60 participants

Demographics: mean age (years): route walking group 42.1 (SD 9.2); incidental walking group 41 (SD 9.7), control group 40.8 (SD 11.4)

Women were predominant in all 3 groups

Mean BMI (kg/m²): route walking group 25.1 (SD 4), incidental walking group 25.4 (SD 4.3), control group 24.2 (SD 3.8)

Interventions

Duration of intervention: 10 weeks

Interventions: walking strategies (route and incidental walking)

Control: no intervention

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Number of steps assessed by an unsealed pedometer (Yamax SW‐200) accompanied by a diary

  • Sitting time (minutes/day) assessed by a logbook

Notes

Authors declared that they had no competing interests.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Pre‐intervention workday step counts and block stratification were used to assign participants at each site randomly and equally to a waiting list control or one of two intervention groups.

Allocation concealment (selection bias)

Unclear risk

Not reported

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

Not reported

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

From a potential sample size of 214 participants, 16% (n = 35) had missing data at pre‐intervention or 2 or more intervention measurement points. These data were removed prior to analyses, resulting in a final sample size of n = 179.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the methods section were reported. The study protocol was not available.

Baseline comparability/ imbalance

Low risk

Age was not significantly different between groups: 42.1 (SD 9.2) years in the route walking group; 41 (SD 9.7) years in the incidental walking group and 40.8 (SD 11.4) years in the control group. Study participants were predominantly women. All participants were white collar workers (i.e. professional, managerial, or administrative).

Validity of outcome measure

Low risk

Paper‐based diaries were used to report sitting time at work.

Gordon 2013

Methods

Random allocation

Unblinded

Study duration: 10 weeks

Dropout: 14%

Location: USA

Recruitment: strategically placed fliers posted around the Arizona State University Downtown Phoenix Campus, email advertisements delivered to employees through the Employee Wellness Committee, and word of mouth.

Participants

Population: currently employed adults with predominantly sedentary occupations working in the Greater Phoenix area in 2012‐2013

Intervention group: 12 participants

Control group: 10 participants

Demographics:

Mean age: intervention 44.2 (SD 12.5), control 47.2 (SD 13.5)

50% females in both groups

BMI: intervention 24.1 (SD 3) kg/m², control 30.6 (SD 5) kg/m²

Intervention group composed of significantly more “official and managerial level” individuals.

Interventions

Duration of intervention: 10 weeks

Intervention: one orientation to walking workstation, 5 bi‐weekly newsletters, specifically targeting workplace sitting behaviours, 5 bi‐weekly FAQ’s and access to study website for intervention content, latest sedentary behaviour research and links for tools for decreasing sitting time at work.

Control: health education

Outcomes

Outcome name, measurement time/tool (units of measurement)

Sitting time/workday (minutes/8‐hour workday) measured by accelerometer‐inclinometer. Participants were also asked to complete a daily log to determine work schedule and verify obtained inclinometer and accelerometer data

Notes

Thesis presented in partial fulfilment of the requirements for the degree Master of Science.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Group allocation was decided by tossing a coin.

Allocation concealment (selection bias)

Unclear risk

Not reported

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

Not reported

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

One participant from both groups withdrew, due to busy schedule; 1 participant from both groups was excluded due to device malfunction; and 1 participant from the control group was excluded due to refusal to wear accelerometer. Intention‐to‐treat analysis was followed for data analysis.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the method section were reported. Study protocol was not available.

Baseline comparability/ imbalance

High risk

Intervention group composed of significantly more “official and managerial level” individuals. Age of participants in the control group was 47.2 (SD 13.5) and in the intervention group was 44.2 (SD 12.5). There were 50% females in both groups. There was significant difference in BMI of participants between intervention and control groups.

Validity of outcome measure

Low risk

The accelerometer is a valid instrument for the measurement of sitting time.

Graves 2015

Methods

Random allocation

Unblinded

Study duration: 8 weeks

Dropout: 4%

Location: UK

Recruitment: consent was sought from 11 departmental managers for employee recruitment. All employees in consenting departments received an overview of the study and participant information sheet, and were invited to a study information session via an email from the research team.

Participants

Population: office workers from one organisation (Liverpool John Moores University, Liverpool, UK). Employees within the approached departments were predominantly administrative staff.

Intervention group: 26 participants

Control group: 21 participants

Demographics:

Mean age: intervention 38.8 (SD 9.8) years, control 38.4 (SD 9.3) years

89% in intervention group and 67% in control group were females

BMI (kg/m²): intervention 67.4 (SD 13.8), control 70.5 (SD 16.4)

Interventions

Duration of intervention: 8 weeks

Intervention: sit‐stand desk combined with face‐to‐face training and ergonomic information.

Control: no intervention

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Sitting time, standing and walking time (minutes/day) measured by paper‐based diary to record

  • Vascular outcomes: B‐mode images of the brachial artery

  • Plasma glucose, triglycerides and total cholesterol

  • Musculoskeletal outcomes on a Likert scale from 0 (no discomfort) to 10 (extremely uncomfortable)

  • Acceptability and feasibility

Notes

Ergotron Ltd provided the sit‐stand desks but had no involvement on the provenance, commissioning, conduct or findings of the study. No other financial disclosures were reported by the authors of this paper.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Participants were randomised using a randomised block design and random number table.

Allocation concealment (selection bias)

High risk

One member of the research team assigned the participants to a treatment arm, based on a design and table with alternating scheme.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Researchers were aware of the allocation and participants may have also been aware of the allocation due to the nature of the intervention.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

The authors conducted a per‐protocol analysis and excluded participants from analyses for outcomes to which they did not contribute data. For workplace sitting, standing and walking, the per‐protocol analysis was compared with an intention‐to‐treat analysis, as a sensitivity analysis.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the method section were reported.

Baseline comparability/ imbalance

Low risk

Groups were comparable at baseline except for a higher proportion of women in the intervention group (89% versus 67% in the control group).

Validity of outcome measure

Low risk

Ecological Momentary Assessment diaries were used to report sitting time at work.

Healy 2013

Methods

Non‐random allocation by clusters (floor): CBA

Unblinded

Study duration: 3 months

Dropout: 14%

Location: Melbourne, Australia

Recruitment: an invitation email was sent to all potential participants to attend one of two 30‐minute study information sessions delivered by research staff. Participants who subsequently expressed interest were screened via telephone for eligibility.

Participants

Population: from a single workplace (Comcare: the government agency responsible for workplace safety, rehabilitation and compensation for Australian government workplaces) in metropolitan Melbourne, Australia

Intervention group: 19 participants

Control group: 19 participants

Demographics: mean age 42.4 (SD 10.6) years in the intervention group and 42.9 (SD 10.3) years in the control group

Women were predominant in the intervention group and men were predominant in the control group.

Mean BMI (kg/m²): intervention group 27.5 (SD 6.1); control group 26.2 (SD 4.6)

Interventions

Duration of intervention: 4 weeks

Intervention: the intervention communicated 3 key messages: “Stand Up, Sit Less, Move More” and had the following components:

  • organisational (a 45‐minute researcher‐led consultation with unit representatives from the intervention group and management followed by a workshop for all intervention participants);

  • environmental (installation of sit–stand desks); and

  • individual elements (30‐minute face‐to‐face consultation with each intervention participant, followed by 3 telephone calls (1/week)).

Control: no intervention

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Sitting, standing, and moving at the workplace (minutes/8‐h workday) assessed by accelerometer‐inclinometer at baseline and their changes at 3‐month follow‐up

  • Weight (kg), waist circumference (cm), hip circumference (cm), fat free mass (kg), fat mass (kg), fasting blood lipids (mmol/L) and glucose (mmol/L) baseline vs. 3 months

  • Self‐reported health‐ and work‐related outcomes baseline vs. 3 months

    • Musculoskeletal symptoms by anatomical regions

    • Other health symptoms: eye strain, headaches, digestion problems, trouble walking, trouble sleeping, fatigue (1‐5 scale)

    • Work‐related outcomes ≥ 1 sick day (in the last month), > 1 day worked while suffering health problems (in the last month), work performance (1‐10 scale)

Notes

This study was funded by an NHMRC project grant and the Victorian Health Promotion Foundation. Ergotron provided the height‐adjustable desks (www.ergotron.com). No financial disclosures were reported by the authors and the authors declared that there were no conflicts of interest.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

Randomisation was not done.

Allocation concealment (selection bias)

High risk

Allocation into groups was by floor, with intervention participants (primarily administrative staff) working on the floor above the control participants (predominantly senior administrative staff).

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Research staff, participants, and assessors were not blinded to group allocation.

Blinding of outcome assessment (detection bias)
All outcomes

High risk

Assessors were not blinded to group allocation.

Incomplete outcome data (attrition bias)
All outcomes

Low risk

4 participants, 2 each from the intervention and control groups withdrew and 2 further participants, 1 each from the intervention and control groups were lost during follow‐up. As the same proportion of participants were excluded from both groups, the missing data did not have much impact on outcomes.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the methods section were reported. The study protocol was not available.

Baseline comparability/ imbalance

Low risk

There were more women in the intervention group than in the control group. The mean age of both groups was similar. All participants were recruited from a single workplace in metropolitan Melbourne, Australia.

Validity of outcome measure

Low risk

The accelerometer is a valid instrument for the measurement of sitting time.

Healy 2016

Methods

Random allocation by clusters

Single‐blind

Study duration: 3 months

Dropout: 12 months

Location: Australia

Recruitment: an information session about the study was presented for consenting teams within each site, with summary material also provided via e‐mail. Employees within these participating teams were then screened by telephone for eligibility.

Participants

Population: staff from the department of human services (a large Australian Government organisation), desk‐based office workers

Intervention group: 7 worksites, 164 participants

Control group: 7 worksites, 144 participants

Demographics:

Mean age in years: intervention 44.6 (SD 9.1), control 47.0 (SD 9.7)

% females: intervention 65.4%, control 72.6%

BMI: intervention group 28.61 (SD 6.46) kg/m², control group 28.61 (SD 5.48) kg/m²

Interventions

Duration: 3 months

Intervention: multicomponent intervention composed of organisational (Consultation workshop, tailored email messages to promote organisational strategies by team champions) environmental (dual screen sit‐stand desk), and individual‐level strategies and targeted change at both the individual and the cluster levels (face to face coaching and telephone calls by study‐trained health coaches).

Control: usual practice

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Changes in sitting/standing/stepping time (minutes/8‐hour workday) and overall sitting time (minutes/16‐hour) measured at 3 months and 12 months. Transitions in positions measured by activPAL3 accelerometer‐inclinometer

  • Adverse events

Notes

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Randomisation was done by generating a randomisation plan for up to 24 clusters in one block

Allocation concealment (selection bias)

High risk

Participants and study staff were unblinded to group allocation.

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

Randomisation was performed by a research staff member not involved in recruitment or data collection. However no information on blinding of participants.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

The sensitivity of results were assessed by using multiple imputation by chained equations.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the protocol section were reported.

Baseline comparability/ imbalance

Low risk

There were more females in the intervention group compared to control group. Both groups were comparable in terms of age and BMI.

Validity of outcome measure

Low risk

activPal accelerometer is a valid instrument for assessing physical activity and sedentary behaviour.

Kress 2014

Methods

Non‐random allocation

Study duration: 6 months

Drop outs: 47%

Location: United States

Recruitment: participants were contacted by email with an invitation to participate in the study

Participants

Population: call centre workers in a company (healthways) in USA. Healthways Inc., a well‐being improvement company with headquarters in Franklin, Tennessee, has multiple call centres in which their Health Coaches, Clinicians (Nurses and Dieticians), and Customer Service Representatives work.

Intervention: sit‐stand desks (45 participants0, standing desks(46 participants)

Control: seated (47 participants)

Demographics: mean age in years: sit‐stand 34.8 (SD 11.5), standing 28.9 (6.8), seated 35 (SD 13.2)

% female participants: sit‐stand 71%, standing 59%, seated 70%

BMI: sit‐stand 29 (SD 9.13), standing 26.8 (SD 5.5), seated 27.8 (SD 5.7)

Interventions

Duration of intervention: 6 months

Sit‐stand desk vs. standing desk

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Self reported changes in sitting/standing (minutes/ workday) measured at 6 months

  • Energy expenditure (calories/minute)

  • Participants experiences with the new workstation at 6 months

Notes

Data for seated group not reported.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

Likely not random and it may be that people swapped desks because of open design of call centre.

Allocation concealment (selection bias)

High risk

Assignment to the workstation type was dependent on Healthways, and it made assignments as random as possible.

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

Not reported

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

High dropout (47% attrition)

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the methods section were reported. The study protocol was not available.

Baseline comparability/ imbalance

Low risk

Mean age of participants was higher for sit‐desk (control) group. Both groups were comparable at baseline for gender and BMI.

Validity of outcome measure

Unclear risk

The armband accelerometer (SenseWear model) is a valid instrument for assessing physical activity and sedentary behaviour

Li 2017

Methods

Random allocation

Single‐blind

Study duration: 5 weeks

Dropout: 18%

Location: Australia

Recruitment: employees were invited to participate through internal email communication.

Participants

Population: employees from the Health Promotion Unit (HPU) of a local health district in the Sydney metropolitan region.

Control group: Group 1 (10 participants)

Intervention group: Group 2 with 8 participants, Group 3 with 7 participants, Group 4 with 7 participants

Demographics:

BMI: intervention group 22.6 (SD 2.6) kg/m², control group 21.5 (SD 2.6) kg/m²

Interventions

Duration: 4 weeks

Control: Group 1 usual seated work

Intervention: sit‐stand desk: Group 2 alternated between 40 minutes sitting and 20 minutes standing, Group 3 alternated between 30 minutes sitting and 30 minutes standing, Group 4 alternated between 20 minutes sitting and 40 minutes standing; in addition all intervention group received email reminders

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Objectively measured total sitting, standing and stepping/walking time, and sit‐to‐stand (STS) transitions during work and non‐work hours assessed by an activPAL accelerometer‐inclinometer and self‐reported using Occupational sitting and physical activity questionnaire and The Active Australia Survey (AAS)

  • Self‐reported leisure time physical activity (LTPA)

  • Sleep duration

Notes

Authors reported no conflict of interest.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Participants were assigned identification codes that were randomised using permuted blocks with block size 8 and 4.

Allocation concealment (selection bias)

Low risk

Group allocation sequence was generated by a study investigator who was not involved in data analysis.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Blinding participants or all members of the research team to group allocation was not possible due to the nature of the trial.

Blinding of outcome assessment (detection bias)
All outcomes

Low risk

The researcher conducting the data analysis was blinded to the group allocation of participants until analyses were completed.

Incomplete outcome data (attrition bias)
All outcomes

High risk

7 participants in intervention and 1 in control group lost to follow‐up (25% attrition rate).

Selective reporting (reporting bias)

High risk

All outcomes mentioned in the study protocol were not reported.

Baseline comparability/ imbalance

Low risk

Intervention and control group were comparable for age, sex and BMI at baseline.

Validity of outcome measure

Low risk

activPal accelerometer is a valid instrument for assessing physical activity and sedentary behaviour

MacEwen 2017

Methods

Random allocation

Single‐blind

Study duration: 3 months

Dropout: 11%

Location: Australia

Recruitment: through posters and word‐of‐mouth

Participants

Population: full‐time desk‐based employees in the Charlottetown area.

Intervention group: 16 participants

Control group: 12 participants

Demographics:

Mean age in years: intervention 43.2 (SD 9.7), control 48.9 (SD 11.4)

BMI: intervention group 36.5 (SD 9) kg/m², control group 34.6 (SD 7) kg/m²

Interventions

Duration: 3 months

Intervention: sit‐stand desk

Control: no sit‐stand desk

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Changes in sitting/standing/stepping time (minutes/8‐hour workday) measured at 12 weeks. Transitions in positions measured by activPAL3 accelerometer‐inclinometer

  • Weight (kg), waist circumference (cm), BMI, body fat %, estimated V02max (ml/min/kg), systolic and diastolic BP (mmHg), fasting blood lipids (Total cholesterol/HDL/LDL/Triglycerides) (mmol/L), glucose (mmol/L), HbA1c (%), aortic augmentation Index (%), subendocardial variability (%) at 12 weeks

Notes

The project was supported by StepsCount, Inc

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Participants were randomly assigned via coin flip to intervention and control group.

Allocation concealment (selection bias)

Unclear risk

Not reported

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

Not reported

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

Four participants were excluded from analysis (14% attrition).

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the study protocol were reported.

Baseline comparability/ imbalance

High risk

Participants in the control group were older (48.9 years, SD 11.4) than the intervention group (43.2 years, SD 9.7) and the intervention group had higher BMI (36.5 kg/m2, SD 9) than the control group (34.6 kg/m2 SD 7).

Validity of outcome measure

Low risk

activPal accelerometer is a valid instrument for assessing physical activity and sedentary behaviour

Mailey 2016

Methods

Random allocation

Single‐blind

Study duration: 9 weeks

Dropout: 22%

Location: United States

Recruitment: university email lists and flyers distributed at local businesses.

Participants

Population: university employees in office settings with set hours (8:00 a.m.‐5:00 p.m.) but not set break schedules

Long break group: 25 participants

Short break group: 24 participants

Demographics:

Mean age in years: long break: 38.92 (SD 7.88), short break: 38.50 (SD8.67)

All participants were females and 60% of them were obese

Interventions

Duration: 8 weeks

Long break (LB) vs. short break (SB)

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Changes in sitting behaviour/light activity/moderate activity (minutes/ workday) measured at 8 weeks, assessed by Actigraph GT3X accelerometer

  • Weight (kg), waist circumference (cm), systolic and diastolic blood pressure, fasting blood lipids (Total cholesterol/Triglycerides) (mmol/L) and glucose (mmol/L) at 8 weeks

Notes

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Participants were randomised to the SB or LB group using a random digit generation Microsoft Excel.

Allocation concealment (selection bias)

Low risk

Participants were randomised to the SB or LB group, by an investigator not involved with testing.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Participants were not blinded to their treatment group assignment.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

Total 11 employees (22.4%) dropped out over 8 weeks. No ITT analysis

Selective reporting (reporting bias)

Low risk

All the outcomes mentioned in the protocol were reported.

Baseline comparability/ imbalance

High risk

Participants assigned to the LB group had higher total cholesterol (P = 0.02) and fewer minutes of sedentary time per workday (P = 0.05) at baseline than participants assigned to the SB group

Validity of outcome measure

Low risk

Actigraph GT3X accelerometer is a valid instrument for assessing physical activity and sedentary behaviour.

Neuhaus 2014a

Methods

Allocation by clusters, 2 groups randomly and 2 group non‐randomly: CBA

Unblinded

Study duration: 3 months

Dropout: 13.6%

Location: University of Queensland, Brisbane, Australia

Recruitment: a recruitment email explaining the study's purpose and procedures was sent to all staff from consenting units. Interested employees emailed the project manager and were interviewed via telephone to assess eligibility.

Participants

Population: desk‐based office workers located on the same office floor, aged between 20–65 years from 3 different campuses

Intervention group:

  • multi component: 12 participants;

  • workstation only: 13 participants.

Control group: 13 participants

Demographics: mean age in the multi component group was 37.3 (SD 10.7) years, 43 (SD 10.2) years in the workstation only group, and 48 (SD 11.6) years in the control group. There were no men in the multi component group, 3 in the workstation only group, and 4 in the control group.

Interventions

Duration of intervention: 3 months

Interventions:

  • multi‐component intervention consisted of the installation of height‐adjustable workstations and organisational‐level (management consultation, staff education, manager emails to staff) and individual‐level (face‐to‐face coaching, telephone support) elements;

  • workstation‐only intervention consisted of the installation of height‐adjustable workstations and occupational health and safety instructions from the project manager.

Control: no intervention

Outcomes

Outcome name, measurement time/tool (units of measurement)

All outcomes were assessed at 3‐month follow‐up

  • Changes in sitting, standing, and moving at work (minutes/8‐h workday) assessed with an accelerometer‐inclinometer

  • Musculoskeletal symptoms by anatomical regions

  • Work related outcomes: work performance, ≥ 1 sick day (in the last month), > 1 day worked while suffering health problems (in the last month)

  • Study feasibility and acceptability

  • Adverse events

Notes

Funding source: Australian Postgraduate Award Scholarship, UQ School of Population Health Top‐Up Scholarship and research student funding, Queensland Health Core Infrastructure Funding, and UQ Major Equipment and Infrastructure and NHMRC Equipment Grant.
Height‐adjustable workstations were provided by Ergotron.

No other financial disclosures were reported by the authors.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

The 2 units that were located closer to the research centre were randomised to the intervention arms and the more distant unit was allocated to the control arm. No further information provided on the method used to generate the random sequence.

Allocation concealment (selection bias)

High risk

The faculty staff were allocated to the multi component group, department staff were allocated to the workstation only group and campus staff were allocated to the control group.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

The participants and personnel knew the group to which they had been allocated.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

25% of participants were lost in the sit‐stand desk plus counselling group, and one participant, i.e. 7% each, in of the other two groups. The high attrition of participants from the sit‐stand desk plus counselling group will have affected the outcome.

Selective reporting (reporting bias)

High risk

Not all the outcomes mentioned in the study protocol were reported.

Baseline comparability/ imbalance

Low risk

All the participants had desk‐based jobs at the University of Queensland in Brisbane, Australia. The mean age in the multi component group was 37.3 (SD 10.7) years, in the workstation only group it was 43 (SD 10.2) years, and 48 (SD 11.6) years in the control group. There were no men in the multi component group, 3 in the workstation only group, and 4 in the control group.

Validity of outcome measure

Low risk

The accelerometer is a valid instrument for the measurement of sitting time.

Pedersen 2013

Methods

Random allocation

Unblinded

Study duration: 13 weeks

No dropouts

Location: Tasmania, Australia

Participants

Population: chosen from 460 desk‐based Tasmania Police employees across several metropolitan sectors

Intervention group: 17 participants

Control group: 17 participants

Demographics: mean age: intervention group 41.5 (SD 12.39) years, control group 43.88 (SD 9.65) years

Interventions

Duration of intervention:13 weeks

Intervention: computer prompts

Control: no intervention

Outcomes

Outcome name, measurement time/tool (units of measurement)

Published: daily workplace energy expenditure (calories/workday) for different activities estimated from occupational physical activity questionnaire at 13 weeks vs. baseline

Unpublished: self‐reported time spent sitting at work (minutes/day) at 13 weeks

Notes

This research was launched through a research partnership between the Tasmania State Police Department and the University of Tasmania; funded by the Tasmanian government’s Healthy@Work grant scheme. The authors report no conflicts of interest.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Following correspondence with the authors, they replied: "We used a random numbers generation software through the web".

Allocation concealment (selection bias)

High risk

Following correspondence with the authors, they replied: "The researchers did randomisation, so we did not blind to the allocation".

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Following correspondence with the authors, they replied: "Since it was field based, participants were not blind to the treatment groups".

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

There were no drop outs or exclusion of data.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the methods section were reported. A study protocol was not available.

Baseline comparability/ imbalance

Low risk

All participants were employees of the Tasmania police department. Age was not significantly different between groups: 41.5 (12.4) years in the intervention group, and 43.88 (9.6) years in the control group.

Validity of outcome measure

Low risk

Occupational Sedentary and Physical Activity Questionnaire (OSPAQ) which had moderate validity was used for assessing time spent sitting at work.

Pickens 2016

Methods

Non‐random allocation: CBA

Study duration: 6 months

Dropout: 45%

Location: United States

Recruitment: email from human resource department of company

Participants

Population: employees of a call centre company in the Eastern United States.

Intervention group: sit‐to‐stand (45 participants) and standing (46 participants)

Control group: seated (47 participants)

Demographics:

Mean age in years: sit‐stand group: 34.8 (SD 11.5), stand group: 28.9 (SD 6.8), seated group: 35.0 (SD 13.2)

% of females: sit‐stand group 71.1%, stand group 58.7%, seated group 70.2%

BMI: sit‐stand group 29.0 (SD 9.13) kg/m², stand group 26.8 (SD 5.5) kg/m², seated group 27.8 (SD 5.7) kg/m²

Interventions

Duration: 3 months

Sit‐to‐stand vs. standing vs. seated workstation

Outcomes

Outcome name, measurement time (units of measurement)

  • Proportion of monitored time in each activity level ‐ sedentary, light, moderate and vigorous activity at 3 months and 6 months

  • Steps per minute at 3 months and 6 months

Notes

Authors have not reported post intervention values for seated control group

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

While not completely random, management did their best to randomise employees between the workstation conditions. The call centre layout and team make‐ups consisted of groups of four to eight workstations. Because of this, and the arrangement within the facility, management kept the type of workstation within each group constant.

Allocation concealment (selection bias)

High risk

Not reported but based on above quote, unlikely the allocation was concealed

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

Not reported

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

High dropout rate at three months (30%) and six months (45%) follow‐up times. No ITT analysis.

Selective reporting (reporting bias)

Low risk

All the outcomes mentioned in the methods section were reported

Baseline comparability/ imbalance

High risk

Age and sex is significantly different where persons using a standing workstation were 5 years younger and had more men. Also many more in this group were ‘health coaches’ and fewer were in customer services.

Validity of outcome measure

Low risk

The questionnaire used to assess activity outcomes in this study were based on the International Physical Activity Questionnaire (IPAQ), and the Modified Occupational Sitting and Physical Activity Questionnaire (OSPAQ)

Priebe 2015

Methods

Random allocation

Study duration: 13 days

Dropout: 32%

Location: Canada

Recruitment: email sent by human resource personnel on the researchers' behalf to potential participants.

Participants

Population: office workers employed in the head office of one large private company in Canada

High personal/high contextual norm (n = 35), high personal/low contextual norm (n = 36), low personal/high contextual norm (n = 35) and low personal/low contextual norm (n = 36)

Demographics:

Mean age in years: 40.30 (SD 12.02)

66% of participants were females

Interventions

Duration: 10 days

High personal/high contextual norm vs. high personal/ ow contextual norm vs. low personal/high contextual norm vs. low personal/low contextual norm

Outcomes

Outcome name, measurement time (units of measurement)

  • Prolonged sitting time (minutes/workday) assessed by self report

  • Standing, walking, and stair use were reported as number of times during the workday assessed by self report

Notes

This work was supported by a Vanier Canada Graduate Scholarship (first author) from the Social Sciences and Humanities Research Council of Canada.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Participants were manually randomly assigned using random number tables to one of four conditions.

Allocation concealment (selection bias)

Unclear risk

Not reported

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

Not reported

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

Very high dropout (32% attrition)

Selective reporting (reporting bias)

Low risk

No protocol. All the outcomes mentioned in the method section were reported.

Baseline comparability/ imbalance

Unclear risk

Not reported

Validity of outcome measure

Unclear risk

Not reported

Puig‐Ribera 2015

Methods

Random allocation by cluster

Single blind

Study duration: 27 weeks

Dropouts: 28%

Location: Spain

Recruitment: office workers were first invited to participate in an on‐line survey to identify those with low and moderate PA levels. Then they were invited to participate in the intervention by email or phone calls.

Participants

Population: administrative and academic staff working at six campuses in four Spanish Universities in Galicia, the Basque Country and Catalonia

Intervention group: 135 participants (3 clusters)

Control group: 129 participants (3 clusters)

Interventions

Duration of intervention: 8 weeks

Intervention: automated web‐based intervention (W@WS) to encourage incidental walking and short walks during the workday. The walking strategies focused on breaking occupational sitting time by incidental walking into work tasks such as moving rather than sitting during lectures and seminars, not sitting to take phone calls, short walks (5–10 minutes) within University campuses, active transport (e.g. walking to work whenever possible) or active lunch breaks.

Control: no intervention

Outcomes

Outcome name, measurement time/tool (units of measurement)

Self‐reported occupational sitting time (minutes/day) measured by paper dairy log

Daily step counts measured by Pedometer, Yamax‐200

Physical risk factors (waist circumference, BMI, blood pressure)

Notes

The study was funded by the Spanish Ministry of Science and Innovation (MICCIN) (project reference DEP 2009‐1147). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Unclear risk

Campuses were randomly assigned by worksite to an intervention (n = 3; deployed W@WS) or comparative group (n = 3; maintained normal behaviour). In each region, one university campus was randomly assigned to the program (intervention group; IG) and another campus acted as a comparison group (CG).

Authors replied to our request for further information but their reasoning was unclear.

Allocation concealment (selection bias)

Unclear risk

Authors replied to our request for further information but their reasoning was unclear.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Following correspondence with authors, they replied: “In the "big universities": the comparison and the intervention campuses were located in different cities and therefore, participants from each campus were not aware that another campus was doing the intervention. In the "small universities": Each university was located in a different city (Barcelona and Vic). Thus, participants did not know there was another university doing the intervention.” However because of the self‐evident nature of the intervention awareness of their own exposure to a certain changed environment or intervention might have changed their behaviour.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

Number of withdrawals was unbalanced in two groups, with more in the intervention group. There were 33 (24%) in the intervention and 41 (32%) in the control group.

Selective reporting (reporting bias)

Low risk

All the outcomes mentioned in the protocol were reported.

Baseline comparability/ imbalance

Unclear risk

Not reported

Validity of outcome measure

Low risk

Paper‐based diary was used to report sitting time at work.

Sandy 2016

Methods

Random allocation

Single‐blind

Study duration: 14 weeks

Dropouts: 14%

Location: Australia

Recruitment: participants were recruited via an email

Participants

Population: employees of Lockheed Martin Mission System and Training business unit: primarily develops software solutions and training/simulation technologies for both civil and commercial markets. 2500 full‐time employees of whom 90% in sedentary computer work for a large percentage of their workday

Intervention group: ergonomic training (16 participants), adjustable desks (23 participants), training and desks (20 participants)

Control group: 13 participants

Demographics: mean age in years: 37.2 (SD 9.4)

BMI: 26.9 (SD 4.4) kg/m2

Interventions

Duration of intervention: 14 weeks

Intervention: Training vs. adjustable desks vs. training and desks

Control: no intervention

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Changes in sitting/standing/walking time (minutes/9‐hour workday) assessed by self report at week 1, 2, 3, 4, 6, 10, 14

  • Discomfort level, musculoskeletal pain, fatigue

Notes

No conflict of interest reported

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Participants were listed out in Excel and randomly placed into one of the four groups.

Allocation concealment (selection bias)

Unclear risk

Not reported

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

Not reported

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

< 10% attrition rate

Selective reporting (reporting bias)

Low risk

No protocol; all the outcomes mentioned in the methods section are reported.

Baseline comparability/ imbalance

Unclear risk

Baseline characteristics of participants not reported

Validity of outcome measure

High risk

Only mentioned self report. No information on validity of questionnaires used.

Schuna 2014

Methods

Random allocation

Single‐blind

Study duration: 3 months

Dropouts: 24%

Location: USA

Recruitment: in‐house distribution of print and electronic media. Potential participants received an email providing a link to an online survey that included a series of screening questions designed to assess participant eligibility.

Participants

Population: pool of 728 overweight/obese and sedentary employees at a single office

Intervention group: 15 participants

Control group: 16 participants

Demographics: mean age: intervention 40 (SD 9.5) years, control 40.3 (SD 10.9) years

One male participant and 40 female participants

BMI: intervention 36.1 (SD 8.7) kg/m², control 35.6 (SD 8.2) kg/m²

Interventions

Duration of intervention: 3 months

Intervention: treadmill desk plus counselling

Control: no intervention

Outcomes

Outcome name, measurement time/tool (units of measurement)

Physical activity (minutes/hour) and sedentary behaviour (minutes/hour) measured by accelerometer‐inclinometer.

Body mass, body fat percentage, and BMI

Notes

This research was supported by Blue Cross and Blue Shield of Louisiana.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Following correspondence with authors, they replied: "Statisticians generated a random list".

Allocation concealment (selection bias)

Low risk

Following correspondence with authors, they replied: “The randomisation codes were sealed in envelopes with randomisation numbers”.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Following correspondence with authors, they replied: “Participants were not blinded. Intervention personnel and Project Manager were not blinded”.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

Does not appear to have attrition bias

Selective reporting (reporting bias)

High risk

The trial registry mentions a follow‐up of 6 months but the study reports only 3 months' follow‐up.

Baseline comparability/ imbalance

Low risk

Age, sex and occupation were similar in both the intervention group and the control group at baseline.

Validity of outcome measure

Low risk

The accelerometer is a valid instrument for the measurement of sitting time.

Swartz 2014

Methods

Random allocation by cluster

Unblinded

Study duration: 6 days

Dropouts: 23%

Location: USA

Recruitment: employees with clerical positions were identified through University directory.

Participants

Population: full‐time employees (employed > 20 years) engaged in a sedentary occupation

Intervention: stand group: 29 participants; step group: 31 participants

Demographics: mean age: stand: 42.3 (SD 11.6) years, step: 46.1 (SD 10.5) years

60% were females in stand group and 75% were females in step group

BMI: stand: 29.3 (SD 7.3) kg/m², step: 27.7 (SD 7.4) kg/m²

Interventions

Duration of intervention: 3 days

Intervention: computer‐based versus wrist worn prompts

Outcomes

Outcome name, measurement time/tool (units of measurement)

Total sitting time (minutes/workday), duration of longest sitting bout (minutes/workday), number of sitting bouts/workday of 30 min or more, standing time (minutes/workday), stepping time, sit/stand transitions measured by accelerometer‐inclinometers.

Notes

The Clinical and Translational Science Institute of Southeastern Wisconsin supported this research.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Random number generation was used to assign participants to either the stand group or step group.

Allocation concealment (selection bias)

Low risk

Assignments were written out and placed in sealed numbered envelopes.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

The envelopes were opened sequentially by a researcher; participants were informed of group assignment.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

18 participants were excluded, 9 each from stand group and step group. Reasons were dropout, equipment malfunction and not wearing monitor properly. The authors did not conduct intention‐to‐treat analysis.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the methods section were reported. The study protocol was not available.

Baseline comparability/ imbalance

Low risk

No baseline differences were found between the two groups for age, body mass, height or BMI.

There was however difference in gender with the Stand group having 60% females and the Step group having 75%.

Validity of outcome measure

Low risk

The accelerometer is a valid instrument for the measurement of sitting time.

Tobin 2016

Methods

Random allocation

Single‐blind

Study duration: 5 weeks

Dropouts: 29%

Location: Australia

Recruitment: participants were recruited via an email sent to all staff working in the study locations

Participants

Population: participants were recruited from four locations across two organisations. The organisations were a non‐government organisation and a university. All locations were office‐based environments.

Intervention group: 26 participants

Control group: 26 participants

Demographics: mean age in years: intervention 34.8 (SD 10.5), control 34.3 (SD 8.9)

% female participants: intervention 89%, control 84%

Interventions

Duration of intervention: 5 weeks

Intervention: sit‐stand desk + instructions/ergonomic assessment

Control: no intervention

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Changes in sitting/standing/stepping time (minutes/8‐hour workday) measured at 5 weeks. Transitions in positions measured by activPAL3 accelerometer‐inclinometer

  • Self‐reported mental health‐ and physical health outcomes

Notes

This study was funded by Healthway (File No: Healthway Promotion Research Agreement 24008). The sit‐stand workstations were supplied by Ergotron (www.ergotron.com).

Authors had no conflicts of interest to report

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Unclear risk

Not reported (only use the word randomised, no protocol to check)

Allocation concealment (selection bias)

Unclear risk

Not reported

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Participants were probably aware of allocation because of self evident nature of intervention.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

Similar proportions of participants were missing from final analysis in both groups.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the method section were reported. Study protocol was not available.

Baseline comparability/ imbalance

Low risk

Participants in control and intervention groups were comparable in age, sex, BMI and education at baseline.

Validity of outcome measure

Low risk

activPAL is a valid instrument for assessment of physical activity and sedentary behaviour

Urda 2016

Methods

Random allocation

Single‐blind

Study duration: 2 weeks

Dropouts: 8%

Location: United States

Recruitment: not reported

Participants

Population: staff at a United States university in desk jobs

Intervention group: 26 participants

Control group: 22 participants

Demographics: mean age in years: 48 (SD 10)

All participants were females

Mean BMI: 30.5 (SD 8.2) kg/m2

Interventions

Duration of intervention: 1 week

Intervention: audible alert and text message every hour and information on behavioural choices and health risks associated with prolonged sitting

Control: no intervention

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Changes in sitting (hours/ workday) measured at 2 weeks. Transitions in positions measured by activPAL3 accelerometer‐inclinometer

  • Perceived wellness score (scale 3 to 29)

Notes

No conflict of interest reported

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Random assignment included assigning participants by table of random numbers to 1 of 2 groups.

Allocation concealment (selection bias)

Unclear risk

Not reported

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Group assignment was doubly blinded until the end of week 1, at which time both the participants and the investigator were aware of group assignment. However, Its not for the duration of intervention

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

Low attrition (8%)

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the method section were reported. Study protocol was not available.

Baseline comparability/ imbalance

Unclear risk

Participants characteristics at baseline not reported

Validity of outcome measure

Low risk

activPAL is a valid instrument for assessing physical activity and sedentary behaviour.

van Berkel 2014

Methods

Random allocation

Unblinded

Study duration: 12 months

Dropout: 11%

Location: Amsterdam, the Netherlands

Participants

Population: all employees from 2 Dutch research institutes were invited to participate, between April and November 2010

Intervention group: 129 participants

Control group: 128 participants

Demographics: mean age of the study population was 46 years

67% of participants were women

About 60% of the study population had a healthy weight (BMI 18.5‐25).

Interventions

Duration of intervention: 6 months but the participants were followed up for 12 months.

Intervention: the Mindful VIP intervention consists of 8 weeks of in‐company mindfulness training with homework exercises, followed by 8 sessions of e–coaching. The homework exercises comprised a variety of formal (“body scan” meditation, sitting meditation) and informal exercises (small exercises, such as breathing exercises when starting up the computer, and grocery shopping mindfully). Additionally, free fruit and snack vegetables were provided during the 6 months. In addition, lunch walking routes, and a buddy‐system were offered as supportive tools.

Control: received information on existing lifestyle behaviour‐related facilities that were already available at the worksite.

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Vigorous physical activity in leisure time (minutes/week) assessed with questionnaire and accelerometer‐inclinometer

  • Sitting at work (minutes/week) assessed with questionnaires

  • Fruit intake (servings/day)

  • Determinants of lifestyle behaviours

Notes

The authors report no conflicts of interest.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

Participants were individually randomised to either the intervention or control group, using a computer‐generated randomisation sequence.

Allocation concealment (selection bias)

High risk

After randomisation, the research assistant notified each participant by email about the group to which he or she was allocated.

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Blinding of the participants and the trainers was not possible.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Not reported

Incomplete outcome data (attrition bias)
All outcomes

Low risk

8 participants were lost to follow‐up from the intervention group and 17 from the control group. The authors conducted intention‐to‐treat analysis by linear mixed‐effect models.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the study protocol were reported.

Baseline comparability/ imbalance

Low risk

Mean age was similar between the intervention group and control group. There were 63.6% women in the intervention group and 71% in the control group. All participants were from two Dutch research institutes.

Validity of outcome measure

High risk

Validity of the questionnaire used in the study has not been tested.

Verweij 2012

Methods

Allocation randomly by cluster

Double‐blind

Study duration: 6 months

Dropout: 43% in occupational physicians (OPs) and 10% in employees

Location: Amsterdam, the Netherlands

Recruitment: OPs were recruited by the Netherlands Society of Occupational Medicine via a direct mailing to their members' registry (> 2100 OPs). OPs were asked to recruit 1 or more companies of medium or large size (> 100 workers). Next, OPs recruited employees via a health risk appraisal consisting of anthropometric measurements and subsequent health advice.

Participants

Population: OPs from the Netherlands Society of Occupational Medicine and employees from medium or large sized companies in the Netherlands

Intervention group: OPs (n = 7), employees (n = 274)

Control group: OPs (n = 9), employees (n = 249)

Demographics: mean age of employees in the intervention group was 46 (SD 8) years, mean age in the control group was 48 (SD 9) years. Percentages of men were 62% and 65% in the intervention and control groups respectively. 33% of employees in the intervention group and 27% of employees in the control group had a normal BMI.

Type of worker

Intervention group: blue collar (manual labour) 15%; white collar 70%; client contact 15%

Control group: blue collar 17%; white collar 73%; client contact 10%

Interventions

Duration of intervention: 6 months

Intervention: guideline‐based counselling by OP providing advice to employers on how to assess and intervene on the obesogenic work environment. Conducted by OPs as 5 face‐to‐face behavioural change counselling sessions for employees to improve their lifestyle to prevent weight gain.

Control: usual care by physician

Outcomes

Outcome name, measurement time/tool (units of measurement)

  • Sitting at work and leisure (minutes/day) assessed by a questionnaire

  • Physical activity assessed by Short questionnaire to assess health enhancing physical activity (SQUASH)

  • Dietary behaviour (daily servings/week): fruit intake assessed by Short Fruit and Vegetable questionnaire, consumption of energy‐dense snacks was assessed by using the fat list

  • Weight‐related measures: waist circumference (cm), body weight (kg) and body height (cm)

Notes

This study was funded by the Netherlands Organisation for Health Research and Development. The authors report no conflicts of interest.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Low risk

OPs who consented to participate were randomly assigned to the intervention or control group by an independent researcher using Random Allocation Software (V.1.0; Isfahan University of Medical Sciences)

Allocation concealment (selection bias)

High risk

After randomisation, the principal researcher notified OPs of the group to which they had been allocated.

Blinding of participants and personnel (performance bias)
All outcomes

Low risk

As OPs themselves were the intervention providers, they could not be blinded for allocation. OPs were asked not to reveal their group to participating employees or assistants performing measurements.

Blinding of outcome assessment (detection bias)
All outcomes

Unclear risk

Waist circumference, body weight and height were measured by unblinded OPs or by blinded clinic employees. However blinding for assessment of sitting was not reported

Incomplete outcome data (attrition bias)
All outcomes

High risk

28 OPs were randomised, but 12 (43%) did not participate in the study at all. However, the remaining OPs recruited employees well, matching the number of planned employees. During the 6‐month intervention period, employees from both groups were lost to follow‐up (7 from the intervention group and 16 from the control group). These subjects (n = 53) were significantly younger, women, and had a lower income than study completers.

Selective reporting (reporting bias)

Low risk

All outcomes mentioned in the study protocol were reported.

Baseline comparability/ imbalance

Low risk

Age, sex and occupation were similar in both the intervention group and the control group at baseline.

Validity of outcome measure

High risk

Validity of the questionnaire used in the study has not been tested.

Abbreviations

BMI: body‐mass index
CBA: controlled before‐and‐after study
h: hour(s)
OP: occupational physician
CP: computer prompts
RCT: randomised controlled trial
SD: standard deviation

Characteristics of excluded studies [ordered by study ID]

Study

Reason for exclusion

Aadahl 2015

Not conducted in a workplace setting.

Did not report workplace sitting, only total sitting.

Adams 2012

Not all the participants were working.

Did not report workplace sitting as a separate outcome. Total sitting time reported.

Aittasalo 2004

Did not report workplace sitting as a separate outcome. Sitting time reported separately for working days and non‐working days but the working days included both work and leisure time.

Alderman 2014

Not RCT or CBA.

Did not report workplace sitting.

Arrogi 2017

Did not report workplace sitting

Audrey 2015

Not conducted in a workplace setting.

Barbieri 2017

Did not report workplace sitting

Ben‐Ner 2014

Did not report data on sitting time at work separately. Daily sitting time (during waking hours) was measured with an accelerometer but it included both work and leisure time.

Berberien 2016

Not RCT or CBA.

Biddle 2015

Not conducted in a workplace setting.

Bird 2014

Not RCT or CBA.

Bjorklund 2015

Did not report workplace sitting

Boreham 2005

This was a stair‐climbing training study that took place during working hours, but sitting time was not assessed.

Bouchard 2015

Not RCT or CBA.

Brown 2012

Did not report workplace sitting.

Buchholz 2016

Not RCT or CBA.

Carr 2013

No data reported for sitting time at work. Daily sedentary time (criterion: 0 steps/minute) was measured with StepWatch (accelerometer attached on ankle), but it included both work and leisure time (the monitor was kept during all wakeful hours for 7 consecutive days). Correspondence with the author was unclear regarding the distinction between work and leisure in sitting time. It is also not clear what the StepWatch measures as an accelerometer.

Carter 2015

Not RCT or CBA. Does not describe a full working day.

Chae 2015

Not RCT or CBA (pre‐post design).

All the participants did not complete the program.

Cheema 2013

Did not report workplace sitting.

Chia 2015

Did not report workplace sitting.

Following correspondence with authors they replied: "We did not specifically measure sitting time but had an indication of the time spent in the office (these are desk bound participants‐ when they filled in the questionnaire of alertness by the hour (0900‐1700hrs)".

Cifuentes 2015

Not RCT or CBA.

Clemes 2014

Not RCT or CBA.

Pedometers were used to record sitting time and step counts.

DeCocker 2015

Not RCT or CBA.

Dewa 2009

Did not report workplace sitting. Sitting time was assessed (IPAQ) but it included both work and leisure time.

Elmer 2014

Not RCT or CBA.

Outcome is energy expenditure not time spent sitting at work.

Engelen 2017

Not RCT or CBA.

Fennell 2017

Did not report workplace sitting

Foley 2016

Not RCT or CBA.

Freak‐Poli 2011

Not an RCT or CBA.

Workplace sitting not reported. Sitting time was questioned separately for weekdays and weekend days but it included both work and leisure.

Ganesan 2016

Did not report workplace sitting

Gardner 2015

Not conducted in a workplace setting.

Gilson 2012

Not an RCT or CBA.

Did not report workplace sitting.

Gilson 2015

Not RCT or CBA.

Gilson ND 2012

Not an RCT or CBA.

Gorman 2013

Not an RCT or CBA.

Green 2016

Not RCT or CBA.

Grunseit 2012

Not an RCT or CBA.

Hadgraft 2017

Did not report workplace sitting

Hedge 2004

Sitting time was not reported in hours (only %).

The length of intervention was not the same for everybody (no detailed information, stated “4‐6 wks”).

Irvine 2011

Not an RCT or CBA.

No quantitative data on sitting time at work.

Jancey 2016

Not RCT or CBA.

John 2011

Not an RCT or CBA.

Did not report workplace sitting. Daily sitting time (waking hours) was measured with an accelerometer, but it included both work and leisure time.

Jones 2017

Did not report workplace sitting

Júdice 2015

Did not report workplace sitting, only total sitting time.

Kennedy 2007

Did not report workplace sitting.

Kerr 2016

Not conducted in a workplace setting.

Koepp 2013

Not an RCT or CBA.

Lara 2008

Not an RCT or CBA.

Did not report workplace sitting.

Liu 2016

Not RCT or CBA.

Maeda 2014

Not RCT or CBA.

Participants were university students.

Mahmud 2015

Did not report workplace sitting

Mainsbridge 2014

Did not report workplace sitting.

Mair 2014

Did not report workplace sitting.

Marshall 2003

Did not report workplace sitting. Sitting time was assessed (IPAQ, short version) but it included both work and leisure time (reported as ‘weekday sitting time’).

McAlpine 2007

Not a normal working day, but an experimental office facility.

Not an RCT or CBA.

Miyachi 2015

Did not report workplace sitting.

NCT01221363

Following correspondence with the authors, they replied: "Ours is not a work place intervention study, but a 'total sitting time' community‐based intervention study where the individual behavioural intervention addresses all domains of life, i.e. leisure time, work, transportation etc. Approximately 1/3 of participants are not working (retired or unemployed) and those who do work, do not necessarily have sedentary work, since our main inclusion criterion was minimum 3.5 hours of leisure time sitting/day. Consequently our primary outcome measure is objectively measured total daily sitting time (activPAL), and we only have rather crude self‐report measures on sitting time at work."

Ognibene 2016

Did not report workplace sitting

Opdenacker 2008

Did not report workplace sitting. Sitting time was assessed (IPAQ) but it included both work and leisure time.

Ouyang 2015

Not conducted in a workplace setting.

Participants were sedentary overweight females.

Parry S 2013

Did not report workplace sitting.

Reported sedentary time measured by accelerometer. Sedentary time was defined as an activity having less than 100 counts on an accelerometer.

Pilcher 2017

Did not report workplace sitting

Poirier 2016

Did not report workplace sitting

Pronk 2012

Not an RCT or CBA.

Roossien 2017

Not RCT or CBA.

Schwartz 2016

Did not report workplace sitting

Slootmaker 2009

Did not report workplace sitting. Daily sitting time (waking hours) was measured with an accelerometer, but it included both work and leisure time.

Sternfeld 2009

Did not report workplace sitting. Sedentary time assessed during leisure.

Straker 2013

Not an RCT or CBA.

Taylor 2016

Did not report workplace sitting

Thogersen‐Ntoumani 2013

Did not report workplace sitting.

Thompson 2014

Did not report workplace sitting. The authors used accelerometers, but converted their results into energy expenditure/day (no separation between work and leisure time).

Thorp 2015

Outcome is energy expenditure not time spent sitting at work.

Torbeyns 2016

Did not report workplace sitting

Torbeyns 2017

Not RCT or CBA.

Tucker 2016

Did not report workplace sitting

vanNassau 2015

Not RCT or CBA.

Wirick 2016

Not conducted in a workplace setting.

Yancey 2004

Did not report workplace sitting.

Østerås 2005

Not an RCT or CBA.

Abbreviations

CBA: controlled before‐and‐after study
IPAQ: International physical activity questionnaire
RCT: randomised controlled trial

Characteristics of studies awaiting assessment [ordered by study ID]

Carpenter 2015

Methods

Randomised controlled trial

Participants

Sedentary office workers (n = 127; ages 22‐64; BMI = 28.5±6.1 kg/m²) were recruited from three Minnesota employers.

Interventions

The intervention consisted of 4 groups for 6 months: 1) Control, 2) Move (30 minutes of light activity during the workday), 3) Stand (standing 50% of the workday using a sit‐stand workstation), or 4) Stand + Move (combined Stand and Move).

Outcomes

Outcomes were assessed at baseline and at 6 months' follow‐up using the following cardiometabolic risk factors: blood pressure, fasting blood glucose, log of fasting triglycerides, and HDL‐cholesterol.

Notes

We could not find the full‐text article.

Dutta 2013

Methods

No information available

Participants

No information available

Interventions

No information available

Outcomes

No information available

Notes

We could not find the full‐text article.

Kirk 2012

Methods

Pre‐post design

Participants

Scottish working adults

Interventions

A 30‐minute individual discussion incorporating cognitive behavioural strategies (e.g. decisional balance, goal setting) to encourage individuals to think about their current sedentary behaviour and strategies to change.

Duration of intervention: 2 weeks

Outcomes

Time spent sitting/lying, standing, stepping, step counts and sit‐to‐stand transitions.

Notes

We could not find the full‐text article.

NCT02932787

Methods

Random allocation

Participants

Desk‐based employees

Interventions

Intervention: height‐adjustable workstation

Control: no intervention

Outcomes

Change in workplace sedentary time assessed at 4 weeks after installation of height‐adjustable workstations, and 4 weeks after removal of height‐adjustable workstations

Change in workplace absenteeism using the World Health Organization Health and Work Performance Questionnaire

Change in workplace presenteeism using the World Health Organization Health and Work Performance Questionnaire

Notes

Principal Investigator: Simon H Till, Sheffield Hallam University

Characteristics of ongoing studies [ordered by study ID]

ACTRN12612001290886

Trial name or title

Methods

Random allocation in clusters

Location: Australia

Recruitment: not yet recruiting

Participants

Population: male and female employees of Rockhampton Regional Council working either full‐time or part‐time, aged 18‐65 years

Interventions

Participants will be asked to wear a pedometer during the 6‐week challenge and to record the number of steps they have taken each day on the Central Queensland University 10,000 Steps website.

Control: no intervention

Outcomes

Primary outcome: total steps of physical activity measured using the Yamax Digiwalker DW‐150 pedometer

Secondary outcomes

  • BMI (kg/m²)

  • Health‐related quality of life, measured using the Australian quality of life scale: AQoL‐15

  • Mood, measured using Depression Anxiety Stress Scales (DASS‐21)

  • Physical activity, measured using self‐reported Active Australia Questionnaire

  • Total minutes of sitting at work, measured using the adapted workforce sitting questionnaire and occupational physical activity questionnaire

Starting date

It is unclear whether the study has started at all. The study was promised to take place in 2013 and the study registration has not been updated.

Contact information

Mitch Duncan, email: [email protected]

Notes

Primary sponsor: Government funding body Central Queensland Hospital and Health Service

ACTRN12614000252617

Trial name or title

Methods

Random allocation

Recruitment: not yet recruiting

Participants

Population: office‐based workers aged 18 years and over, working at least 0.6 full‐time equivalent

Interventions

The organisational plus technology support intervention lasts for 8 weeks and consists of the following components:

  • a participant information session (30‐45 minutes);

  • an electronic information booklet;

  • a unit representatives' consultation workshop (2‐4 hours);

  • the training of team managers;

  • PLUS technology support: participants will wear a LUMOback posture sensor device around their waists for 8 weeks.

Control: will receive all the elements of the intervention except PLUS technology support.

Outcomes

Primary outcome

  • Daily sitting time and workplace sitting time assessed objectively using an activPAL accelerometer‐inclinometers

Secondary outcomes

  • Mediators and moderators of any change

  • Reliability and validity of the LUMOback

  • Standing and moving time (a) at the workplace and (b) across the day

Starting date

It is unclear whether the study has started despite mentioning anticipated date of first participant enrolment 17/03/2014. The study registration has not been updated.

Contact information

Genevieve Healy, email: [email protected]

Notes

Primary sponsor: University Cancer Prevention Research Centre, The University of Queensland, Australia

Bergman 2015

Trial name or title

The Inphact treadmill study

Methods

Random allocation

Location: Sweden

Recruitment: recruitment and screening of participants has been completed.

Participants

Population description: healthy overweight and obese office workers (n = 80) with mainly sedentary tasks will be recruited from office workplaces in Umeå, Sweden.

Interventions

The intervention group will receive a health consultation and a treadmill desk, which they will use for at least one hour per day for 13 months.

Control: the control group will receive the same health consultation, but continue to work at their regular workstations.

Outcomes

Primary outcome:

Physical activity and sedentary time during workdays and non‐workdays as well as during working and non‐working hours on workdays will be measured objectively using accelerometers (Actigraph and activPAL) at baseline and after 2, 6, 10, and 13 months of follow‐up.

Secondary outcome:

Food intake will be recorded and metabolic and anthropometric variables, body composition, stress, pain, depression, anxiety, cognitive function, and functional magnetic resonance imaging will be measured at 3–5 time points during the study period.

Starting date

November 2013

Contact information

Tommy Olsson, email: [email protected]

Notes

Sponsors: Not reported

Buman 2017

Trial name or title

Stand & Move at Work

Methods

Random allocation by clusters

Location: United States

Recruitment: not yet recruiting

Participants

Population description: worksites will be enrolled in the greater Phoenix, AZ, USA and Minneapolis, MN, USA metropolitan regions. Selected worksites will be drawn from three distinct work sectors: higher education, industry/healthcare (e.g., law firms, health insurance providers), and government (e.g. state departments).

Interventions

Multicomponent interventions comprising of sit‐stand workstation, e‐newsletter, individualised coaching, prompts and engagement of worksite administrators and managers to enact policy‐level workplace modifications

Outcomes

Primary outcomes: time spent sitting and LPA at work, will be assessed with the activPAL3 accelerometer‐inclinometer

Secondary outcomes: cardiometabolic risk, workplace productivity, work engagement, and workplace satisfaction

Starting date

Contact information

Matthew P. Buman, email address: [email protected]

Notes

Study supported by the National Institutes of Health [R01CA198971].

Dunstan 2014

Trial name or title

Stand Up Victoria

Methods

Random allocation

Location: Australia

Recruitment: not yet recruiting

Participants

Population description: employees aged 18‐65 years, from 16 work sites located in Victoria, Australia

Interventions

The intervention consists of four distinct components:

  • an initial unit representatives' consultation;

  • a whole‐of‐workplace Information session;

  • environmental modification involving installation of sit‐stand workstations for individual participants;

  • support for behavioural change which includes:

    • an initial one‐on‐one individual consultation with project staff;

    • 4 telephone support calls over 3 months;

  • support for behavioural change which includes:

    • an initial one‐on‐one individual consultation with project staff;

    • 4 telephone support calls over 3 months.

Control: no intervention

Outcomes

Primary outcome

  • A 30 minutes/day reduction in objectively‐assessed (using physical activity monitors) workplace sedentary time

  • An increase of 5 breaks/day in workplace sedentary time, objectively measured using physical activity monitors

Secondary outcomes

Examine the effect of the intervention on cardiometabolic markers of health and disease including:

  • body composition including waist circumference, BMI, and percent fat mass;

  • fasting blood levels of glucose, insulin and lipids;

  • blood pressure.

Explore workplace and individual‐level mediators (how did the intervention work?) and moderators (for whom did it work?) of change using a specially formulated questionnaire.

Starting date

July 2011

Contact information

David Dunstan, email: [email protected]

Notes

Sponsors: National Health and Medical Research Council and Vic Health

Finkelstein 2015

Trial name or title

TRial of Economic Incentives to Promote Physical Activity (TRIPPA)

Methods

Random allocation

Location: Singapore

Recruitment: on a rolling basis, and in two steps. In the first step, companies were engaged through existing contacts and “cold calls”. If companies responded positively, a study briefing was conducted to apprise the management of study details. Once we received confirmation of participation from the management team, we proceeded to step two of the recruitment process. Recruitment materials (e.g., electronic direct mails, posters, and newsletters) communicating the nature of the research study were disseminated to employees through internal channels unique to each company. The materials directed potential participants to the study website for additional information. Employees were also invited to attend a presentation conducted by the study team at each participating worksite.

Participants

Population description: employees from 13 companies spanning 15 worksites in Singapore

Interventions

4 arms: “basic package” comprising two educational booklets, Fitbit arm, two incentive arms (cash or charity)

Outcomes

Primary outcome: MVPA bout minutes/week as measured via accelerometry

Secondary outcomes:

  • daily and weekly steps, total minutes of sedentary/light, moderate and vigorous physical activity per week (counts all moderate and vigorous minutes, including those that do not meet the criteria for MVPA bouts);

  • adherence to the commonly cited 10,000 steps/day target;

  • changes in body mass index (BMI) and systolic blood pressure;

  • quality of life as measured by the EuroQoL's EQ‐5D‐5L instrument, productivity losses as measured by the Work Productivity and Activity Impairment (WPAI) scale;

  • cardiorespiratory fitness assessed by Non‐Exercise Fitness Test (NEFT;)

  • cost‐effectiveness outcomes.

Starting date

Contact information

Eric A. Finkelstein, e‐mail address: eric.finkelstein@duke‐nus.edu.sg

Notes

This study is supported by the Singapore Ministry of Health's Health Services Research Competitive Research Grant (HSRG/022/2012).

Finni 2011

Trial name or title

Methods

Random allocation

Location: Finland

Recruitment: recruitment is performed in the city of Jyväskylä, Finland, by delivering advertisements to parents via kindergartens and primary schools that have been pre‐randomised to control and intervention groups after balancing different environmental and socioeconomic regions within the city.

Participants

Population description: families from Jyväskylä region, Finland

Interventions

Tailored counselling targeted to decrease sitting time by focusing on commuting and work time.

Control: no intervention

Outcomes

Changes in physical activity, health‐related indices and maintenance of the behavioural change

Starting date

December 2011

Contact information

Taija Juutinen, email: [email protected]

Notes

Study sponsors: Ministry of Education and Culture, Finland

Hall 2015

Trial name or title

Take A Stand for Workplace Health: A Sit‐stand Workstation Project Evaluation

Methods

Random allocation

Recruitment: active, not recruiting

Participants

Population: office employees primarily engaged in desk‐based work at one of the two worksites involved in the study (Macmillan Cancer Support, Public Health England)

Interventions

Duration of intervention: 12 months

Three‐arm trial

Intervention: a sit‐stand workstation only and a multi‐component sit‐stand workstation intervention including individual and organisation‐level approaches

Control: usual practice (seated workstation)

Outcomes

  • Objective measures of sitting, standing, and physical activity using ActivPAL3™ and ActiGraph (GT3X+)

  • Understanding of the influence of organisational culture on sitting, standing and physical activity behaviour in the workplace using qualitative methods

Starting date

May 2014

Contact information

Jenifer Hall, email: [email protected]

Notes

Sponsors and collaborators: Brunel University, Macmillan Cancer Support, Ergotron, Public Health England

ISRCTN25767399

Trial name or title

Booster breaks: health promoting work breaks

Methods

Random allocation

Participants

Population: employees with sedentary office jobs from four workplaces in a large, urban southwestern U.S. city.

Interventions

Three‐arm trial

Intervention: Computer Prompt (individualized PA work breaks) group and Booster Break group

Control: usual break group

Outcomes

Primary outcomes: lipid profile, blood pressure, height, weight, International Physical Activity Questionnaire (IPAQ), pedometer readings

Secondary outcomes: physical activity mediators and employee and organisational psychosocial constructs: self‐report assessments.

Starting date

January 2009

Contact information

Wendell Taylor, email: [email protected]

Notes

Sponsor: National Institutes of Health (USA)

Mackey 2011

Trial name or title

Methods

Random allocation

Location: Australia

Participants

Population: employees of 1 of 3 of the university’s campuses located in Sydney and Melbourne, working on a part‐time or full‐time basis in either a job with an academic or administrative designation.

Interventions

Duration of intervention: 12 weeks

The intervention will comprise 2 distinct treatment phases targeting behaviour adoption (weeks 1‐4) and adherence (weeks 5‐12) using 'stages of behaviour change' principles

  • Adoption phase of the walking intervention will consist of individually targeted, supervised, 60‐minute education/information group sessions of 5‐6 participants held once a week

  • The adherence phase of the walking intervention will be self‐directed and remotely monitored to encourage participant compliance and progression. Participants will select their own preferred walking option(s) from 3 alternatives, walking routes, walking within tasks (walk and talk seminars or meetings) or walking for transport. Participants will be encouraged to select a mix of the options from day‐to‐day depending on their preferences.

Control: no intervention

Outcomes

Primary outcome:

Average workday step count: measured by pedometer (Yamax SW‐200) and averaged over 5 workdays at each time point

Secondary outcomes

  • Mental health status: the psychological well‐being of participants will be measured by a validated self‐administered questionnaire; Kessler‐10

  • Physical activity participation will be measured by the validated Active Australia Survey

  • Physical health status will be measured by 3 standard measures of cardiovascular and metabolic health

    • Blood pressure

    • Waist circumference

    • Body fat percentage

    • Work ability

Starting date

March 2010

Contact information

Martin Mackey, email: [email protected]

Notes

Study sponsors: Australian Research Council: ARC (Industry) Linkage Grant

Professor Philip Taylor

Mantzari 2016

Trial name or title

Methods

Random allocation

Location: United Kingdom

Recruitment: will be recruited through: 1) employment databases and invited via letter/email, and 2) adverts in local newsletters and flyers posted within the buildings of target organisations.

Participants

Population description: office‐based employees from two companies in Cambridge, UK

Interventions

Intervention: sit‐stand desks

Control: no intervention

Outcomes

  • Physical activity energy expenditure estimated via Actiheart monitors

  • Sedentary behaviour measured using activPAL inclinometers: sitting time during a) working hours (workplace sitting time) and b) all waking hours (total sitting time); sitting patterns (number of sit‐to‐stand transitions; sitting time accrued in prolonged bouts (≥ 30 min)) during a) working hours (workplace sitting patterns) and b) all waking hours (total sitting patterns)

  • Cardio‐metabolic related outcomes: BMI calculated from weight and height; weight measured using a scale; height measured using a stadiometer; fat mass and fat‐free mass measured via a spectroscopy device; blood pressure, measured via an electronic monitor; waist‐hip circumference measured using a tape measure; plasma total cholesterol, HDL, triglycerides and HbA1C, measured via non‐fasting blood tests

  • Musculoskeletal discomfort measured using the Nordic Musculoskeletal Questionnaire [80]

  • Ability to work, work productivity, presenteeism, absenteeism and job satisfaction measured using the Work ability index

Starting date

Contact information

Correspondence: [email protected]

Notes

The study is supported by a grant from the Department of Health Policy Research Program (Policy Research Unit in Behaviour and Health [PR‐UN‐0409‐10109]), the Medical Research Council (Unit Programme number MC_UU_12015/3) and the British Heart Foundation (Intermediate Basic Science Research Fellowship grant FS/12/58/29709 to KW)

Martin‐Borras 2014

Trial name or title

SedestActiv Project

Methods

Random allocation

Location: Spain

Recruitment: a total of 232 subjects will be randomly allocated to an intervention and control group (116 individuals each group). In addition, 50 subjects with fibromyalgia will be included.

Participants

Population description: professionals from 13 primary health care centres will randomly invite mildly obese or overweight patients of both genders, aged 25‐65 years, to participate.

Interventions

6‐month primary care intervention

Control: no intervention

Outcomes

Duration of intervention: 6 months

Primary outcome: to assess the effectiveness of a 6‐month primary care intervention to reduce diary hours of sitting time in overweight and obese patients, as well as to increase their weekly energy expenditure

Secondary outcomes

  • Number of steps walked

  • Subjective level of physical activity

  • Quality of life related to health

  • Blood pressure

  • Skin folds and waist circumference

  • Triglycerides, total cholesterol and glucose

Starting date

June 2012

Contact information

Carme Martín‐Borràs

Email: [email protected]

Notes

Study sponsor: Jordi Gol i Gurina Foundation

NCT01787643

Trial name or title

Methods

Random allocation

Recruitment: active, not recruiting

Participants

Population: sedentary office employees

Interventions

Height‐adjustable desk installation in office

Outcomes

Primary outcome: workplace sitting time

Secondary outcomes

  • Total sitting time

  • Energy expenditure

  • Body weight, BMI, fat mass reduction

  • Changes in musculoskeletal symptoms

  • Increase in standing behaviour

Starting date

January 2013

Contact information

Notes

Study sponsor: USDA (United States Department of Agriculture) Grand Forks Human Nutrition Research Center

NCT01846013

Trial name or title

Methods

Random allocation

Recruitment: active, not recruiting

Participants

Population: sedentary employees who use a single computer workstation for the majority of their workday

Interventions

Sit‐stand workstation with three arms

  • Stand: standing for at least half of the workday at work (4 hours)

  • Move: increase movement time at work. Move more by making small changes (walking meetings, take stairs, etc.)

  • Stand and Move: increase standing time to half of workday (4h) and increase movement time at work.

Outcomes

  • Total physical activity

  • Fasting blood glucose

  • Total cholesterol

  • Body composition

Starting date

November 2013

Contact information

Notes

Study sponsor: University of Minnesota ‐ Clinical and Translational Science Institute

NCT02376504

Trial name or title

Modifying the workplace to decrease sedentary behaviour and improve health

Methods

Random allocation

Participants

Healthy volunteers employed in a full‐time sedentary job

Interventions

Duration of intervention: 12 months

Three‐arm trial

Intervention: treadmill workstation and sit‐stand workstation

Control: participants will be asked to engage in three 10 min walking bouts each workday

Outcomes

Change in weight

Starting date

April 2014

Contact information

Anne Thorndike, email: [email protected]

Notes

Study sponsor: Northeastern University

NCT02609282

Trial name or title

Methods

Random allocation

Participants

Employees from 10 organisations involved with the Healthy Working Lives initiative

Interventions

Duration of intervention: 12 weeks

Intervention: hourly prompts to stand for a period of 10 weeks plus education on why and how to reduce prolonged sitting

Control: education on why and how to reduce prolonged sitting

Outcomes

Total time spent sitting at work, accessed by 7 day ActivPal and diary measurement

Time spent sitting in prolonged sedentary bouts at work

Number of sitting events at work

Number of prolonged sitting events at work

Starting date

1 February 2015

Contact information

Notes

Pricinpal Investigator: Philippa Dall, PhD

NCT02785640

Trial name or title

Methods

Random allocation

Participants

Desk‐based office employees

Interventions

Duration: 12 weeks

Intervention: an education session on the health benefits of breaking prolonged sitting and feedback on baseline sitting behaviour followed by hourly prompts to stand delivered by Microsoft Outlook for a period of 10 weeks. The messages will be short in length, varied and centre around the key message of breaking prolonged sitting by standing.

Control: same education session as the prompt group, as well as feedback on their baseline sitting behaviour.

Outcomes

Total time spent sitting at work will be objectively measured using a tri‐axial accelerometer

Total time spent sitting at work in continuous bouts of at least 30 minutes

Number of sitting events at work

Number of prolonged sitting events at work

Time after prompt to stand

Starting date

March 2016

Contact information

Philippa Dall, PhD

Notes

NCT03236597

Trial name or title

Methods

Random allocation

Participants

Desk‐based employees

Interventions

Treadmill workstation versus sit‐stand workstation

Outcomes

  • Time spent sitting, standing, and moving measured by the ActivPAL at 7 days follow‐up

  • Cardiometabolic risk profile measured via a composite score of fasting glucose, insulin, triglycerides, HDL‐cholesterol and blood pressure

Starting date

August 2017

Contact information

Mark Pereira, [email protected]

Notes

O’Connell 2015

Trial name or title

SMArT Work: Stand More AT Work

Methods

Random allocation in clusters

Location: UK

Recruitment: participant recruitment will be coordinated via the research team at the Leicester Diabetes Centre. The study team currently hold a database of office units within the University Hospitals of Leicester NHS Trust and will promote this study to them initially through the use of the Trust’s intranet and emails to department managers. This will be followed up with a face‐to‐face presentation/meeting if necessary.

Participants

Desk‐based office workers (n = 238) from a stratified sample of NHS staff (e.g. employees, managers, gender, job role)

Interventions

Height‐adjustable workstations at the environmental, organisational and individual level that support less occupational sitting.

Outcomes

  • Primary outcome is a reduction in sitting time, measured by the activPALTM micro at 12 months.

  • Secondary outcomes include objectively measured physical activity and a variety of work‐related health and psycho‐social measures.

Starting date

October 2014

Contact information

Dr Ben Jackson, email: [email protected]

Notes

Radas 2013

Trial name or title

The Healthier Office Study

Methods

Quasi‐random allocation

Location: Australia

Recruitment: "Posters will be placed in staff tearooms and common areas, inviting staff to participate. The advertisements will contain general information informing participants that we are testing simple occupational health interventions and that participants will be provided with an ergonomic device or advice about improving healthy work practices. The study will also be advertised at Faculty staff meetings to improve potential participants’ awareness of the study"

Participants

Population description: participants will be recruited from academic and administrative staff of The University of Sydney, Sydney, Australia

Interventions

Intervention: 3 groups (1 control group and 2 intervention groups) will be conducted in an office workplace setting. The education intervention group will receive an education package that encourages reduction in sitting behaviours. The sit‐stand desk intervention group will receive the same education package along with an adjustable sit‐stand desk.

The control group will receive no information or advice about postural change and no modification to their office desk set‐up.

Outcomes

Average daily sedentary time during work hours, measured by an accelerometer

Starting date

March 2013

Contact information

Notes

Study sponsors: this research is supported by funding from the Heart Foundation, Sydney, NSW, Australia, and by Australian National Health and Medical Research Council Program Grant (number: 569940; AB). Sit‐stand workstations were donated by Sit Back and Relax, Alexandria, NSW, Australia.

Van Hoye 2012

Trial name or title

Methods

Random allocation

Location: Belgium

Recruitment: all participants were recruited from working places in Flanders (Belgium) through flyers, emails, pharmacists, and word of mouth

Participants

Population: employees (male and female) aged 19‐67 years who mentioned not being physically active during the last year

Interventions

Interventions: Participants were randomised into one of the following four intervention groups.

  • A minimal intervention group received no feedback

  • A pedometer group was provided only with information on their daily step count

  • A display group received feedback on calories burned, steps taken, and minutes of physical activity by means of the sense wear armband (SWA) display

  • A coaching group also received the SWA display and had weekly meetings with a personal coach

Outcomes

Primary outcome: physical activity level

Secondary outcomes

  • Step count, minutes of physical (in)activity (sedentary, light, moderate, vigorous, and very vigorous intensity physical activity)

  • Daily energy expenditure in physical activity

  • Percent of participants losing fat

  • Stages of motivational readiness for physical activity

Starting date

Contact information

Notes

No conflict of interest

Abbreviation

BMI: body mass index

Data and analyses

Open in table viewer
Comparison 1. Sit‐stand desk with or without information and counselling versus sit‐desk

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work follow‐up short‐term Show forest plot

10

323

Mean Difference (Random, 95% CI)

‐100.16 [‐115.83, ‐84.48]

Analysis 1.1

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 1 Mean difference in time spent sitting at work follow‐up short‐term.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 1 Mean difference in time spent sitting at work follow‐up short‐term.

1.1 Sit‐stand desk only

5

145

Mean Difference (Random, 95% CI)

‐96.72 [‐126.05, ‐67.39]

1.2 Sit‐stand desk + information and counselling

6

178

Mean Difference (Random, 95% CI)

‐104.38 [‐122.81, ‐85.96]

2 Mean difference in time spent sitting at work, follow‐up short‐term ‐ sensitivity analysis Show forest plot

10

323

Mean Difference (Random, 95% CI)

‐100.16 [‐115.83, ‐84.48]

Analysis 1.2

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 2 Mean difference in time spent sitting at work, follow‐up short‐term ‐ sensitivity analysis.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 2 Mean difference in time spent sitting at work, follow‐up short‐term ‐ sensitivity analysis.

2.1 Randomised control trials

4

132

Mean Difference (Random, 95% CI)

‐105.19 [‐128.13, ‐82.24]

2.2 Cross‐over RCT

2

70

Mean Difference (Random, 95% CI)

‐99.11 [‐112.82, ‐85.41]

2.3 Control before after studies

4

121

Mean Difference (Random, 95% CI)

‐92.80 [‐133.13, ‐52.47]

3 Mean difference in time spent sitting at work. follow‐up medium‐term (CBA) Show forest plot

2

60

Mean Difference (Fixed, 95% CI)

‐57.08 [‐98.76, ‐15.41]

Analysis 1.3

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 3 Mean difference in time spent sitting at work. follow‐up medium‐term (CBA).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 3 Mean difference in time spent sitting at work. follow‐up medium‐term (CBA).

4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term (CBA) Show forest plot

2

74

Mean Difference (Fixed, 95% CI)

‐52.57 [‐78.79, ‐26.35]

Analysis 1.4

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term (CBA).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term (CBA).

4.1 Sit‐stand desk only

1

20

Mean Difference (Fixed, 95% CI)

‐13.00 [‐70.80, 40.80]

4.2 Sit‐stand desk + information and counselling

2

54

Mean Difference (Fixed, 95% CI)

‐63.22 [‐92.92, ‐33.51]

5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term Show forest plot

2

56

Mean Difference (Fixed, 95% CI)

‐81.67 [‐123.99, ‐39.36]

Analysis 1.5

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

6 Mean difference in time spent standing at work, follow‐up short‐term Show forest plot

9

295

Mean Difference (Fixed, 95% CI)

89.38 [76.44, 102.32]

Analysis 1.6

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 6 Mean difference in time spent standing at work, follow‐up short‐term.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 6 Mean difference in time spent standing at work, follow‐up short‐term.

6.1 Sit‐stand desk only

4

117

Mean Difference (Fixed, 95% CI)

75.78 [57.56, 94.01]

6.2 Sit‐stand desk + information and counselling

6

178

Mean Difference (Fixed, 95% CI)

103.20 [84.83, 121.58]

7 Mean difference in time spent standing at work, follow‐up short‐term (RCT only) Show forest plot

4

132

Mean Difference (Fixed, 95% CI)

98.65 [74.94, 122.36]

Analysis 1.7

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 7 Mean difference in time spent standing at work, follow‐up short‐term (RCT only).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 7 Mean difference in time spent standing at work, follow‐up short‐term (RCT only).

8 Mean difference in time spent stepping at work follow‐up short‐term Show forest plot

8

270

Mean Difference (Random, 95% CI)

‐0.52 [‐3.88, 2.85]

Analysis 1.8

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 8 Mean difference in time spent stepping at work follow‐up short‐term.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 8 Mean difference in time spent stepping at work follow‐up short‐term.

9 Mean difference in time spent standng at work, follow‐up medium‐term (CBA) Show forest plot

2

60

Mean Difference (IV, Fixed, 95% CI)

53.36 [16.59, 90.14]

Analysis 1.9

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 9 Mean difference in time spent standng at work, follow‐up medium‐term (CBA).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 9 Mean difference in time spent standng at work, follow‐up medium‐term (CBA).

10 Work performance (1‐10 scale), follow‐up short‐term (CBA) Show forest plot

3

109

Mean Difference (Fixed, 95% CI)

0.35 [‐0.10, 0.79]

Analysis 1.10

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 10 Work performance (1‐10 scale), follow‐up short‐term (CBA).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 10 Work performance (1‐10 scale), follow‐up short‐term (CBA).

10.1 Sit‐stand desk only

2

52

Mean Difference (Fixed, 95% CI)

0.82 [0.00, 1.63]

10.2 Sit‐stand desk + information and counselling

2

57

Mean Difference (Fixed, 95% CI)

0.15 [‐0.38, 0.68]

11 Proportion with ≥ 1 sick days in the last three months (CBA) Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

Analysis 1.11

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 11 Proportion with ≥ 1 sick days in the last three months (CBA).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 11 Proportion with ≥ 1 sick days in the last three months (CBA).

12 Proportion with ≥ 1 sick days in the last month (CBA) Show forest plot

2

78

Risk Ratio (M‐H, Fixed, 95% CI)

0.77 [0.49, 1.21]

Analysis 1.12

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 12 Proportion with ≥ 1 sick days in the last month (CBA).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 12 Proportion with ≥ 1 sick days in the last month (CBA).

12.1 Sit‐stand desk only

1

20

Risk Ratio (M‐H, Fixed, 95% CI)

0.94 [0.42, 2.13]

12.2 Sit‐stand desk + information and counselling

2

58

Risk Ratio (M‐H, Fixed, 95% CI)

0.72 [0.41, 1.24]

13 Mean difference in musculoskeletal symptoms, follow‐up short‐term Show forest plot

1

46

Mean Difference (Fixed, 95% CI)

‐0.51 [‐1.03, ‐0.00]

Analysis 1.13

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 13 Mean difference in musculoskeletal symptoms, follow‐up short‐term.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 13 Mean difference in musculoskeletal symptoms, follow‐up short‐term.

14 Mean difference in musculoskeletal symptoms, follow‐up Medium‐term Show forest plot

1

45

Mean Difference (Fixed, 95% CI)

‐0.54 [‐0.89, ‐0.19]

Analysis 1.14

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 14 Mean difference in musculoskeletal symptoms, follow‐up Medium‐term.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 14 Mean difference in musculoskeletal symptoms, follow‐up Medium‐term.

Open in table viewer
Comparison 2. Standing desk versus sit‐stand desk

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 2.1

Comparison 2 Standing desk versus sit‐stand desk, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Comparison 2 Standing desk versus sit‐stand desk, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

2 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 2.2

Comparison 2 Standing desk versus sit‐stand desk, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 2 Standing desk versus sit‐stand desk, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Open in table viewer
Comparison 3. Active workstation versus sit desk

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 3.1

Comparison 3 Active workstation versus sit desk, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Comparison 3 Active workstation versus sit desk, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

1.1 Treadmill desk plus counselling versus sit desk

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

2 Mean difference in time spent in inactive sitting at work, follow‐up medium term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 3.2

Comparison 3 Active workstation versus sit desk, Outcome 2 Mean difference in time spent in inactive sitting at work, follow‐up medium term.

Comparison 3 Active workstation versus sit desk, Outcome 2 Mean difference in time spent in inactive sitting at work, follow‐up medium term.

2.1 Cycling desk + information and counselling versus information and counselling only

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

Open in table viewer
Comparison 4. Walking strategies versus no intervention

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short term Show forest plot

1

179

Mean Difference (Fixed, 95% CI)

‐15.49 [‐49.65, 18.67]

Analysis 4.1

Comparison 4 Walking strategies versus no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up short term.

Comparison 4 Walking strategies versus no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up short term.

1.1 Route versus no intervention

1

90

Mean Difference (Fixed, 95% CI)

‐16.0 [‐64.98, 32.98]

1.2 Incidental versus no intervention

1

89

Mean Difference (Fixed, 95% CI)

‐15.0 [‐62.66, 32.66]

2 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

1

264

Mean Difference (IV, Fixed, 95% CI)

‐16.50 [‐60.55, 27.55]

Analysis 4.2

Comparison 4 Walking strategies versus no intervention, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 4 Walking strategies versus no intervention, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

3 Percentage of lost work productivity (WLQ Index Score) follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 4.3

Comparison 4 Walking strategies versus no intervention, Outcome 3 Percentage of lost work productivity (WLQ Index Score) follow‐up medium‐term.

Comparison 4 Walking strategies versus no intervention, Outcome 3 Percentage of lost work productivity (WLQ Index Score) follow‐up medium‐term.

Open in table viewer
Comparison 5. Short break versus long break

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 5.1

Comparison 5 Short break versus long break, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Comparison 5 Short break versus long break, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Open in table viewer
Comparison 6. Information, feedback and/or reminder versus information only or no intervention

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short term Show forest plot

2

63

Mean Difference (IV, Fixed, 95% CI)

‐19.23 [‐57.05, 18.58]

Analysis 6.1

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up short term.

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up short term.

1.1 Information and feedback versus no intervention

2

63

Mean Difference (IV, Fixed, 95% CI)

‐19.23 [‐57.05, 18.58]

2 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

2

747

Mean Difference (Fixed, 95% CI)

‐28.38 [‐51.49, ‐5.26]

Analysis 6.2

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

2.1 Counselling versus no intervention

2

747

Mean Difference (Fixed, 95% CI)

‐28.38 [‐51.49, ‐5.26]

3 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Subtotals only

Analysis 6.3

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 3 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 3 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

3.1 Information and feedback versus no intervention

1

37

Mean Difference (Fixed, 95% CI)

‐16.40 [‐96.85, 64.06]

4 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Subtotals only

Analysis 6.4

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 4 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium term.

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 4 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium term.

4.1 Counselling versus no intervention

1

416

Mean Difference (Fixed, 95% CI)

‐20.0 [‐85.00, 45.00]

5 Mean difference in time spent standing at work follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Subtotals only

Analysis 6.5

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 5 Mean difference in time spent standing at work follow‐up short‐term.

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 5 Mean difference in time spent standing at work follow‐up short‐term.

5.1 Information and feedback

1

93

Mean Difference (Fixed, 95% CI)

10.24 [‐17.17, 37.65]

6 Work engagement (0‐6 scale), follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Subtotals only

Analysis 6.6

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 6 Work engagement (0‐6 scale), follow‐up medium‐term.

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 6 Work engagement (0‐6 scale), follow‐up medium‐term.

6.1 Counseling versus no intervention

1

224

Mean Difference (Fixed, 95% CI)

0.1 [‐0.10, 0.30]

Open in table viewer
Comparison 7. Prompts plus information versus information alone

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short term Show forest plot

2

75

Mean Difference (IV, Fixed, 95% CI)

‐10.48 [‐44.88, 23.92]

Analysis 7.1

Comparison 7 Prompts plus information versus information alone, Outcome 1 Mean difference in time spent sitting at work, follow‐up short term.

Comparison 7 Prompts plus information versus information alone, Outcome 1 Mean difference in time spent sitting at work, follow‐up short term.

2 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

1

34

Mean Difference (Fixed, 95% CI)

‐54.92 [‐95.82, ‐14.02]

Analysis 7.2

Comparison 7 Prompts plus information versus information alone, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 7 Prompts plus information versus information alone, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

3 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 7.3

Comparison 7 Prompts plus information versus information alone, Outcome 3 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 7 Prompts plus information versus information alone, Outcome 3 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term.

4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

1

28

Mean Difference (Fixed, 95% CI)

‐73.92 [‐123.78, ‐24.06]

Analysis 7.4

Comparison 7 Prompts plus information versus information alone, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 7 Prompts plus information versus information alone, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.

5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 7.5

Comparison 7 Prompts plus information versus information alone, Outcome 5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

Comparison 7 Prompts plus information versus information alone, Outcome 5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

6 Mean difference in time spent standing at work follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 7.6

Comparison 7 Prompts plus information versus information alone, Outcome 6 Mean difference in time spent standing at work follow‐up short‐term.

Comparison 7 Prompts plus information versus information alone, Outcome 6 Mean difference in time spent standing at work follow‐up short‐term.

7 Mean difference in energy expenditure, follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 7.7

Comparison 7 Prompts plus information versus information alone, Outcome 7 Mean difference in energy expenditure, follow‐up medium‐term.

Comparison 7 Prompts plus information versus information alone, Outcome 7 Mean difference in energy expenditure, follow‐up medium‐term.

Open in table viewer
Comparison 8. Computer prompts to step versus computer prompts to stand

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 8.1

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

2 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 8.2

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 2 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 2 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term.

3 Mean difference in time spent standing at work, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 8.3

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 3 Mean difference in time spent standing at work, follow‐up short‐term.

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 3 Mean difference in time spent standing at work, follow‐up short‐term.

4 Mean difference in time spent stepping at work, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 8.4

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 4 Mean difference in time spent stepping at work, follow‐up short‐term.

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 4 Mean difference in time spent stepping at work, follow‐up short‐term.

Open in table viewer
Comparison 9. High personalised or contextualised information versus less personalised or contextualised information

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 9.1

Comparison 9 High personalised or contextualised information versus less personalised or contextualised information, Outcome 1 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 9 High personalised or contextualised information versus less personalised or contextualised information, Outcome 1 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Open in table viewer
Comparison 10. Mindfulness training versus no intervention

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

1

257

Mean Difference (Fixed, 95% CI)

‐22.69 [‐62.55, 17.17]

Analysis 10.1

Comparison 10 Mindfulness training versus no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 10 Mindfulness training versus no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up medium‐term.

2 Work engagement (0‐6 scale), follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 10.2

Comparison 10 Mindfulness training versus no intervention, Outcome 2 Work engagement (0‐6 scale), follow‐up medium‐term.

Comparison 10 Mindfulness training versus no intervention, Outcome 2 Work engagement (0‐6 scale), follow‐up medium‐term.

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Comparison 11. Activity tracker combined with organisational support versus organisational support only

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 11.1

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

2 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 11.2

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

3 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 11.3

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 3 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 3 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.

4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up medium‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 11.4

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up medium‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up medium‐term.

5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 11.5

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

6 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 11.6

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 6 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 6 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium‐term.

7 Mean difference in time spent standing at work follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 11.7

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 7 Mean difference in time spent standing at work follow‐up short‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 7 Mean difference in time spent standing at work follow‐up short‐term.

8 Mean difference in time spent stepping at work, follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 11.8

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 8 Mean difference in time spent stepping at work, follow‐up short‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 8 Mean difference in time spent stepping at work, follow‐up short‐term.

9 Mean difference in time spent standing at work follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 11.9

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 9 Mean difference in time spent standing at work follow‐up medium‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 9 Mean difference in time spent standing at work follow‐up medium‐term.

10 Mean difference in time spent stepping at work, follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 11.10

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 10 Mean difference in time spent stepping at work, follow‐up medium‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 10 Mean difference in time spent stepping at work, follow‐up medium‐term.

Open in table viewer
Comparison 12. Multi‐component intervention versus no intervention

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short‐term Show forest plot

3

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 12.1

Comparison 12 Multi‐component intervention versus no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

2 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

2

562

Mean Difference (IV, Fixed, 95% CI)

‐45.60 [‐62.54, ‐28.66]

Analysis 12.2

Comparison 12 Multi‐component intervention versus no intervention, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

3 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 12.3

Comparison 12 Multi‐component intervention versus no intervention, Outcome 3 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 3 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term.

4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

2

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 12.4

Comparison 12 Multi‐component intervention versus no intervention, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.

5 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 12.5

Comparison 12 Multi‐component intervention versus no intervention, Outcome 5 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up medium‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 5 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up medium‐term.

6 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term Show forest plot

2

227

Mean Difference (Fixed, 95% CI)

‐72.73 [‐91.87, ‐53.59]

Analysis 12.6

Comparison 12 Multi‐component intervention versus no intervention, Outcome 6 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 6 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

7 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 12.7

Comparison 12 Multi‐component intervention versus no intervention, Outcome 7 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 7 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium‐term.

8 Mean difference in time spent standing at work follow‐up short‐term Show forest plot

2

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 12.8

Comparison 12 Multi‐component intervention versus no intervention, Outcome 8 Mean difference in time spent standing at work follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 8 Mean difference in time spent standing at work follow‐up short‐term.

9 Mean difference in time spent stepping at work follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 12.9

Comparison 12 Multi‐component intervention versus no intervention, Outcome 9 Mean difference in time spent stepping at work follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 9 Mean difference in time spent stepping at work follow‐up short‐term.

10 Mean difference in time spent standing at work follow‐up medium‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 12.10

Comparison 12 Multi‐component intervention versus no intervention, Outcome 10 Mean difference in time spent standing at work follow‐up medium‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 10 Mean difference in time spent standing at work follow‐up medium‐term.

11 Mean difference in time spent stepping at work follow‐up medium‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Analysis 12.11

Comparison 12 Multi‐component intervention versus no intervention, Outcome 11 Mean difference in time spent stepping at work follow‐up medium‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 11 Mean difference in time spent stepping at work follow‐up medium‐term.

12 Work engagement (0‐6 scale), follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

0.0 [‐0.14, 0.14]

Analysis 12.12

Comparison 12 Multi‐component intervention versus no intervention, Outcome 12 Work engagement (0‐6 scale), follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 12 Work engagement (0‐6 scale), follow‐up short‐term.

12.1 Environmental interventions only

1

Mean Difference (Fixed, 95% CI)

0.1 [‐0.10, 0.30]

12.2 Environmental interventions + counselling

1

Mean Difference (Fixed, 95% CI)

‐0.1 [‐0.30, 0.10]

13 Mean difference in musculoskeletal symptoms all sites (score 0–6) at short‐term follow‐up Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Analysis 12.13

Comparison 12 Multi‐component intervention versus no intervention, Outcome 13 Mean difference in musculoskeletal symptoms all sites (score 0–6) at short‐term follow‐up.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 13 Mean difference in musculoskeletal symptoms all sites (score 0–6) at short‐term follow‐up.

PRISMA study flow diagram
Figuras y tablas -
Figure 1

PRISMA study flow diagram

Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
Figuras y tablas -
Figure 2

Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.

Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
Figuras y tablas -
Figure 3

Risk of bias summary: review authors' judgements about each risk of bias item for each included study.

Funnel plot of comparison: 1 Sit‐stand desk with or without information and counselling versus sit‐desk, outcome: 1.1 Mean difference in time spent sitting at work: short‐term follow‐up.
Figuras y tablas -
Figure 4

Funnel plot of comparison: 1 Sit‐stand desk with or without information and counselling versus sit‐desk, outcome: 1.1 Mean difference in time spent sitting at work: short‐term follow‐up.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 1 Mean difference in time spent sitting at work follow‐up short‐term.
Figuras y tablas -
Analysis 1.1

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 1 Mean difference in time spent sitting at work follow‐up short‐term.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 2 Mean difference in time spent sitting at work, follow‐up short‐term ‐ sensitivity analysis.
Figuras y tablas -
Analysis 1.2

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 2 Mean difference in time spent sitting at work, follow‐up short‐term ‐ sensitivity analysis.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 3 Mean difference in time spent sitting at work. follow‐up medium‐term (CBA).
Figuras y tablas -
Analysis 1.3

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 3 Mean difference in time spent sitting at work. follow‐up medium‐term (CBA).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term (CBA).
Figuras y tablas -
Analysis 1.4

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term (CBA).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.
Figuras y tablas -
Analysis 1.5

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 6 Mean difference in time spent standing at work, follow‐up short‐term.
Figuras y tablas -
Analysis 1.6

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 6 Mean difference in time spent standing at work, follow‐up short‐term.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 7 Mean difference in time spent standing at work, follow‐up short‐term (RCT only).
Figuras y tablas -
Analysis 1.7

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 7 Mean difference in time spent standing at work, follow‐up short‐term (RCT only).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 8 Mean difference in time spent stepping at work follow‐up short‐term.
Figuras y tablas -
Analysis 1.8

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 8 Mean difference in time spent stepping at work follow‐up short‐term.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 9 Mean difference in time spent standng at work, follow‐up medium‐term (CBA).
Figuras y tablas -
Analysis 1.9

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 9 Mean difference in time spent standng at work, follow‐up medium‐term (CBA).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 10 Work performance (1‐10 scale), follow‐up short‐term (CBA).
Figuras y tablas -
Analysis 1.10

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 10 Work performance (1‐10 scale), follow‐up short‐term (CBA).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 11 Proportion with ≥ 1 sick days in the last three months (CBA).
Figuras y tablas -
Analysis 1.11

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 11 Proportion with ≥ 1 sick days in the last three months (CBA).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 12 Proportion with ≥ 1 sick days in the last month (CBA).
Figuras y tablas -
Analysis 1.12

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 12 Proportion with ≥ 1 sick days in the last month (CBA).

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 13 Mean difference in musculoskeletal symptoms, follow‐up short‐term.
Figuras y tablas -
Analysis 1.13

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 13 Mean difference in musculoskeletal symptoms, follow‐up short‐term.

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 14 Mean difference in musculoskeletal symptoms, follow‐up Medium‐term.
Figuras y tablas -
Analysis 1.14

Comparison 1 Sit‐stand desk with or without information and counselling versus sit‐desk, Outcome 14 Mean difference in musculoskeletal symptoms, follow‐up Medium‐term.

Comparison 2 Standing desk versus sit‐stand desk, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.
Figuras y tablas -
Analysis 2.1

Comparison 2 Standing desk versus sit‐stand desk, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Comparison 2 Standing desk versus sit‐stand desk, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.
Figuras y tablas -
Analysis 2.2

Comparison 2 Standing desk versus sit‐stand desk, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 3 Active workstation versus sit desk, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.
Figuras y tablas -
Analysis 3.1

Comparison 3 Active workstation versus sit desk, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Comparison 3 Active workstation versus sit desk, Outcome 2 Mean difference in time spent in inactive sitting at work, follow‐up medium term.
Figuras y tablas -
Analysis 3.2

Comparison 3 Active workstation versus sit desk, Outcome 2 Mean difference in time spent in inactive sitting at work, follow‐up medium term.

Comparison 4 Walking strategies versus no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up short term.
Figuras y tablas -
Analysis 4.1

Comparison 4 Walking strategies versus no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up short term.

Comparison 4 Walking strategies versus no intervention, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.
Figuras y tablas -
Analysis 4.2

Comparison 4 Walking strategies versus no intervention, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 4 Walking strategies versus no intervention, Outcome 3 Percentage of lost work productivity (WLQ Index Score) follow‐up medium‐term.
Figuras y tablas -
Analysis 4.3

Comparison 4 Walking strategies versus no intervention, Outcome 3 Percentage of lost work productivity (WLQ Index Score) follow‐up medium‐term.

Comparison 5 Short break versus long break, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.
Figuras y tablas -
Analysis 5.1

Comparison 5 Short break versus long break, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up short term.
Figuras y tablas -
Analysis 6.1

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up short term.

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.
Figuras y tablas -
Analysis 6.2

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 3 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.
Figuras y tablas -
Analysis 6.3

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 3 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 4 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium term.
Figuras y tablas -
Analysis 6.4

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 4 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium term.

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 5 Mean difference in time spent standing at work follow‐up short‐term.
Figuras y tablas -
Analysis 6.5

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 5 Mean difference in time spent standing at work follow‐up short‐term.

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 6 Work engagement (0‐6 scale), follow‐up medium‐term.
Figuras y tablas -
Analysis 6.6

Comparison 6 Information, feedback and/or reminder versus information only or no intervention, Outcome 6 Work engagement (0‐6 scale), follow‐up medium‐term.

Comparison 7 Prompts plus information versus information alone, Outcome 1 Mean difference in time spent sitting at work, follow‐up short term.
Figuras y tablas -
Analysis 7.1

Comparison 7 Prompts plus information versus information alone, Outcome 1 Mean difference in time spent sitting at work, follow‐up short term.

Comparison 7 Prompts plus information versus information alone, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.
Figuras y tablas -
Analysis 7.2

Comparison 7 Prompts plus information versus information alone, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 7 Prompts plus information versus information alone, Outcome 3 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term.
Figuras y tablas -
Analysis 7.3

Comparison 7 Prompts plus information versus information alone, Outcome 3 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 7 Prompts plus information versus information alone, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.
Figuras y tablas -
Analysis 7.4

Comparison 7 Prompts plus information versus information alone, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 7 Prompts plus information versus information alone, Outcome 5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.
Figuras y tablas -
Analysis 7.5

Comparison 7 Prompts plus information versus information alone, Outcome 5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

Comparison 7 Prompts plus information versus information alone, Outcome 6 Mean difference in time spent standing at work follow‐up short‐term.
Figuras y tablas -
Analysis 7.6

Comparison 7 Prompts plus information versus information alone, Outcome 6 Mean difference in time spent standing at work follow‐up short‐term.

Comparison 7 Prompts plus information versus information alone, Outcome 7 Mean difference in energy expenditure, follow‐up medium‐term.
Figuras y tablas -
Analysis 7.7

Comparison 7 Prompts plus information versus information alone, Outcome 7 Mean difference in energy expenditure, follow‐up medium‐term.

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.
Figuras y tablas -
Analysis 8.1

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 2 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term.
Figuras y tablas -
Analysis 8.2

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 2 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 3 Mean difference in time spent standing at work, follow‐up short‐term.
Figuras y tablas -
Analysis 8.3

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 3 Mean difference in time spent standing at work, follow‐up short‐term.

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 4 Mean difference in time spent stepping at work, follow‐up short‐term.
Figuras y tablas -
Analysis 8.4

Comparison 8 Computer prompts to step versus computer prompts to stand, Outcome 4 Mean difference in time spent stepping at work, follow‐up short‐term.

Comparison 9 High personalised or contextualised information versus less personalised or contextualised information, Outcome 1 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.
Figuras y tablas -
Analysis 9.1

Comparison 9 High personalised or contextualised information versus less personalised or contextualised information, Outcome 1 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 10 Mindfulness training versus no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up medium‐term.
Figuras y tablas -
Analysis 10.1

Comparison 10 Mindfulness training versus no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 10 Mindfulness training versus no intervention, Outcome 2 Work engagement (0‐6 scale), follow‐up medium‐term.
Figuras y tablas -
Analysis 10.2

Comparison 10 Mindfulness training versus no intervention, Outcome 2 Work engagement (0‐6 scale), follow‐up medium‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.
Figuras y tablas -
Analysis 11.1

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.
Figuras y tablas -
Analysis 11.2

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 3 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.
Figuras y tablas -
Analysis 11.3

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 3 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up medium‐term.
Figuras y tablas -
Analysis 11.4

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up medium‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.
Figuras y tablas -
Analysis 11.5

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 6 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium‐term.
Figuras y tablas -
Analysis 11.6

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 6 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 7 Mean difference in time spent standing at work follow‐up short‐term.
Figuras y tablas -
Analysis 11.7

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 7 Mean difference in time spent standing at work follow‐up short‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 8 Mean difference in time spent stepping at work, follow‐up short‐term.
Figuras y tablas -
Analysis 11.8

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 8 Mean difference in time spent stepping at work, follow‐up short‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 9 Mean difference in time spent standing at work follow‐up medium‐term.
Figuras y tablas -
Analysis 11.9

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 9 Mean difference in time spent standing at work follow‐up medium‐term.

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 10 Mean difference in time spent stepping at work, follow‐up medium‐term.
Figuras y tablas -
Analysis 11.10

Comparison 11 Activity tracker combined with organisational support versus organisational support only, Outcome 10 Mean difference in time spent stepping at work, follow‐up medium‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.
Figuras y tablas -
Analysis 12.1

Comparison 12 Multi‐component intervention versus no intervention, Outcome 1 Mean difference in time spent sitting at work, follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.
Figuras y tablas -
Analysis 12.2

Comparison 12 Multi‐component intervention versus no intervention, Outcome 2 Mean difference in time spent sitting at work, follow‐up medium‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 3 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term.
Figuras y tablas -
Analysis 12.3

Comparison 12 Multi‐component intervention versus no intervention, Outcome 3 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.
Figuras y tablas -
Analysis 12.4

Comparison 12 Multi‐component intervention versus no intervention, Outcome 4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 5 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up medium‐term.
Figuras y tablas -
Analysis 12.5

Comparison 12 Multi‐component intervention versus no intervention, Outcome 5 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up medium‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 6 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.
Figuras y tablas -
Analysis 12.6

Comparison 12 Multi‐component intervention versus no intervention, Outcome 6 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 7 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium‐term.
Figuras y tablas -
Analysis 12.7

Comparison 12 Multi‐component intervention versus no intervention, Outcome 7 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 8 Mean difference in time spent standing at work follow‐up short‐term.
Figuras y tablas -
Analysis 12.8

Comparison 12 Multi‐component intervention versus no intervention, Outcome 8 Mean difference in time spent standing at work follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 9 Mean difference in time spent stepping at work follow‐up short‐term.
Figuras y tablas -
Analysis 12.9

Comparison 12 Multi‐component intervention versus no intervention, Outcome 9 Mean difference in time spent stepping at work follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 10 Mean difference in time spent standing at work follow‐up medium‐term.
Figuras y tablas -
Analysis 12.10

Comparison 12 Multi‐component intervention versus no intervention, Outcome 10 Mean difference in time spent standing at work follow‐up medium‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 11 Mean difference in time spent stepping at work follow‐up medium‐term.
Figuras y tablas -
Analysis 12.11

Comparison 12 Multi‐component intervention versus no intervention, Outcome 11 Mean difference in time spent stepping at work follow‐up medium‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 12 Work engagement (0‐6 scale), follow‐up short‐term.
Figuras y tablas -
Analysis 12.12

Comparison 12 Multi‐component intervention versus no intervention, Outcome 12 Work engagement (0‐6 scale), follow‐up short‐term.

Comparison 12 Multi‐component intervention versus no intervention, Outcome 13 Mean difference in musculoskeletal symptoms all sites (score 0–6) at short‐term follow‐up.
Figuras y tablas -
Analysis 12.13

Comparison 12 Multi‐component intervention versus no intervention, Outcome 13 Mean difference in musculoskeletal symptoms all sites (score 0–6) at short‐term follow‐up.

Summary of findings for the main comparison. Alternative desks and workstations compared to sit‐desks for reducing sitting at work

Alternative desks and workstations compared to sit‐desks for reducing sitting at work

Patient or population: employees who sit at work
Setting: workplace
Intervention: alternative desks and workstations
Comparison: sit‐desks

Outcomes

Anticipated absolute effects* (95% CI)

№ of participants
(studies)

Certainty of the evidence
(GRADE)

Comments

Risk with sit‐desk

Risk with changes in desk

Comparison: sit‐stand desk with or without information and counselling versus sit‐desk

Mean difference in time spent sitting at work, short‐term follow‐up (up to 3 months)

The mean difference in time spent sitting at work (short‐term follow‐up) was 364 minutes

MD 100 minutes lower
(116 lower to 84 lower)

323
(10 studies: 4 RCTs, 2 cross‐over RCTs, 4 CBAs)

⊕⊕⊝⊝
LOW 1 2

Subgroup analysis showed no difference in effect between sit‐stand desks used alone or in combination with information and counselling. Restricting the analysis to RCTs only did not show any difference in effect either.

Mean difference in time in sitting bouts lasting 30 minutes or more, short‐term follow‐up

The mean difference in time in sitting bouts lasting 30 minutes or more (short‐term follow‐up) was 167 minutes

MD 53 minutes lower
(79 lower to 26 lower)

74
(2 CBAs)

⊕⊝⊝⊝
VERY LOW 2 3

Comparison: treadmill desk combined with counselling versus sit‐desk

Mean difference in time spent sitting at work, short‐term follow‐up (up to 3 months)

The mean difference in time spent sitting at work (short‐term follow‐up) was 342 minutes

MD 29 minutes lower
(55 lower to 2 lower)

31
(1 RCT)

⊕⊕⊝⊝
LOW 2 4

Mean difference in time in sitting bouts lasting 30 minutes or more, short‐term follow‐up — not reported

Comparison: cycling desk + information and counselling versus sit‐desk + information and counselling

Mean difference in time spent in inactive sitting at work, medium‐term follow‐up (from 3 to 12 months)

The mean difference in time spent in inactive sitting at work (medium‐term follow‐up) was 413 minutes

MD 12 minutes lower
(24 lower to 1 higher)

54
(1 RCT)

⊕⊕⊝⊝
LOW 2 5

*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: Confidence interval; RR: Risk ratio; OR: Odds ratio; RCT: randomised controlled trial CBA: controlled before‐and‐after study; MD: mean difference

GRADE Working Group grades of evidence
High certainty: We are very confident that the true effect lies close to that of the estimate of the effect
Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect
Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

1 Of the six RCTs, five were at high risk of bias. The non‐randomised controlled before‐and‐after study/studies were also at high risk of bias; downgraded one level

2 Imprecision with wide confidence intervals, small sample size; downgraded one level

3 Unconcealed allocation, unblinded outcome assessment and attrition bias; downgraded two levels

4 Unblinded outcome assessment; downgraded one level

5 Unblinded outcome assessment and attrition bias; downgraded one level

Figuras y tablas -
Summary of findings for the main comparison. Alternative desks and workstations compared to sit‐desks for reducing sitting at work
Summary of findings 2. Workplace policy changes compared to no intervention or alternate intervention for reducing sitting at work

Workplace policy changes compared to no intervention for reducing sitting at work

Patient or population: employees who sit at work
Setting: workplace
Intervention: policy changes
Comparison: no intervention

Outcomes

Anticipated absolute effects* (95% CI)

№ of participants
(studies)

Certainty of the evidence
(GRADE)

Comments

Risk with no intervention

Risk with Policy changes

Comparision: walking strategies versus no intervention

Mean difference in time spent sitting at work, short‐term follow‐up

The mean difference in time spent sitting at work (short‐term follow‐up) was 344 minutes

MD 15 minutes lower
(50 lower to 19 higher)

179
(1 RCT)

⊕⊕⊝⊝
LOW 1 2

Mean difference in time in sitting bouts lasting 30 minutes or more, short‐term follow‐up — not reported

Comparision: short break versus long break

Mean difference in time spent sitting at work, short‐term follow‐up

The mean difference in time spent sitting at work (short term follow‐up) was 131 minutes

MD 40 minutes lower
(66 lower to 15 lower)

49
(1 RCT)

⊕⊕⊝⊝
LOW 2 3

Mean difference in time in sitting bouts lasting 30 minutes or more, short‐term follow‐up — not reported

*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: Confidence interval; RR: Risk ratio; OR: Odds ratio; RCT: randomised controlled trial; MD: mean difference

GRADE Working Group grades of evidence
High certainty: We are very confident that the true effect lies close to that of the estimate of the effect
Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect
Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

1 Risk of bias high due to unblinded outcome assessment and lack of allocation concealment; downgraded with one level

2 Imprecision with wide confidence intervals; downgraded with one level

3 Unconcealed allocation and attrition bias

Figuras y tablas -
Summary of findings 2. Workplace policy changes compared to no intervention or alternate intervention for reducing sitting at work
Summary of findings 3. Information, feedback, and/or counselling compared to information only or no intervention for reducing sitting at work

Information and counselling compared to information only or no intervention for reducing sitting at work

Patient or population: employees who sit at work
Setting: workplace
Intervention: information and counselling
Comparison: information only or no intervention

Outcomes

Anticipated absolute effects* (95% CI)

№ of participants
(studies)

Certainty of the evidence
(GRADE)

Comments

Risk with information only or no intervention

Risk with Information and counselling

Information, feedback and counselling versus no intervention

Mean difference in time spent sitting at work, short‐term follow‐up — information and feedback versus no intervention

The mean difference in time spent sitting at work (short‐term follow‐up) was 550 minutes

MD 19 minutes lower
(57 lower to 19 higher)

63
(2 RCTs)

⊕⊕⊝⊝
LOW 1 2

Mean difference in time spent sitting at work, medium‐term follow‐up — counselling versus no intervention

The mean difference in time spent sitting at work (medium‐term follow‐up) was 462 minutes

MD 28 minutes lower
(51 lower to 5 lower)

747
(2 RCTs)

⊕⊕⊝⊝
LOW 1 3

Mean difference in time in sitting bouts lasting 30 minutes or more, short‐term follow‐up ‐ not reported

Prompts combined with information versus information alone

Mean difference in time spent sitting at work, short‐term follow‐up

The mean difference in time spent sitting at work (short‐term follow‐up) was 349 minutes

MD 10 minutes lower
(45 lower to 24 higher)

75
(2 RCTs)

⊕⊕⊝⊝
LOW 1 2

Mean difference in time in sitting bouts lasting 30 minutes or more, short‐term follow‐up

The mean difference in time in sitting bouts lasting 30 minutes or more (short‐term follow‐up) was 286 minutes

MD 74 minutes lower
(124 lower to 24 lower)

28
(1 RCT)

⊕⊕⊝⊝
LOW 1 4

Mindfulness training versus no intervention

Mean difference in time spent sitting at work, medium‐term follow‐up

The mean difference in time spent sitting at work (medium‐term follow‐up) was 316 minutes

MD 23 minutes lower
(63 lower to 17 higher)

257
(1 RCT)

⊕⊕⊝⊝
LOW 1 6

Mean difference in time in sitting bouts lasting 30 minutes or more, medium‐term follow‐up — not reported

*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: Confidence interval; RR: Risk ratio; OR: Odds ratio; RCT: randomised controlled trial; MD: mean difference

GRADE Working Group grades of evidence
High certainty: We are very confident that the true effect lies close to that of the estimate of the effect
Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect
Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

1 Imprecision with wide confidence intervals, small sample size; downgraded with one level

2 Unblinded outcome assessment and attrition bas

3 Risk of bias, allocation not concealed, lack of blinding, high attrition rate; downgraded with one level

4 Lack of blinding of participants and selective reporting

5 Lack of blinding of participants and attrition bias

6 Risk of bias high due to unconcealed allocation and unblinded outcome assessment; downgraded with one level

7 Lack of blinding of participants

Figuras y tablas -
Summary of findings 3. Information, feedback, and/or counselling compared to information only or no intervention for reducing sitting at work
Summary of findings 4. Multi‐component intervention compared to no intervention for reducing sitting at work

Multi‐component intervention compared to no intervention for reducing sitting at work

Patient or population: employees who sit at work
Setting: workplace
Intervention: multi‐component intervention
Comparison: no intervention

Outcomes

Anticipated absolute effects* (95% CI)

№ of participants
(studies)

Certainty of the evidence
(GRADE)

Comments

Risk with no intervention

Risk with Multi‐component intervention

Mean difference in time spent sitting at work, short‐term follow‐up

See comment

see comment

573
(3 RCTs)

⊕⊝⊝⊝
VERY LOW 1 2 3

Not pooled

Mean difference in time in sitting bouts lasting 30 minutes or more, short‐term follow‐up

See comment

See comment

518
(2 RCTs)

⊕⊝⊝⊝
VERY LOW 1 2 3

Not pooled

*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).

CI: Confidence interval; RR: Risk ratio; OR: Odds ratio; RCT: randomised controlled trial

GRADE Working Group grades of evidence
High certainty: We are very confident that the true effect lies close to that of the estimate of the effect
Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect
Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

1 Unconcealed allocation and unblinded outcome assessment

2 Imprecision with wide confidence interval, small sample size

3 Not pooled due to high heterogeneity

3 Small sample size

Figuras y tablas -
Summary of findings 4. Multi‐component intervention compared to no intervention for reducing sitting at work
Comparison 1. Sit‐stand desk with or without information and counselling versus sit‐desk

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work follow‐up short‐term Show forest plot

10

323

Mean Difference (Random, 95% CI)

‐100.16 [‐115.83, ‐84.48]

1.1 Sit‐stand desk only

5

145

Mean Difference (Random, 95% CI)

‐96.72 [‐126.05, ‐67.39]

1.2 Sit‐stand desk + information and counselling

6

178

Mean Difference (Random, 95% CI)

‐104.38 [‐122.81, ‐85.96]

2 Mean difference in time spent sitting at work, follow‐up short‐term ‐ sensitivity analysis Show forest plot

10

323

Mean Difference (Random, 95% CI)

‐100.16 [‐115.83, ‐84.48]

2.1 Randomised control trials

4

132

Mean Difference (Random, 95% CI)

‐105.19 [‐128.13, ‐82.24]

2.2 Cross‐over RCT

2

70

Mean Difference (Random, 95% CI)

‐99.11 [‐112.82, ‐85.41]

2.3 Control before after studies

4

121

Mean Difference (Random, 95% CI)

‐92.80 [‐133.13, ‐52.47]

3 Mean difference in time spent sitting at work. follow‐up medium‐term (CBA) Show forest plot

2

60

Mean Difference (Fixed, 95% CI)

‐57.08 [‐98.76, ‐15.41]

4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term (CBA) Show forest plot

2

74

Mean Difference (Fixed, 95% CI)

‐52.57 [‐78.79, ‐26.35]

4.1 Sit‐stand desk only

1

20

Mean Difference (Fixed, 95% CI)

‐13.00 [‐70.80, 40.80]

4.2 Sit‐stand desk + information and counselling

2

54

Mean Difference (Fixed, 95% CI)

‐63.22 [‐92.92, ‐33.51]

5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term Show forest plot

2

56

Mean Difference (Fixed, 95% CI)

‐81.67 [‐123.99, ‐39.36]

6 Mean difference in time spent standing at work, follow‐up short‐term Show forest plot

9

295

Mean Difference (Fixed, 95% CI)

89.38 [76.44, 102.32]

6.1 Sit‐stand desk only

4

117

Mean Difference (Fixed, 95% CI)

75.78 [57.56, 94.01]

6.2 Sit‐stand desk + information and counselling

6

178

Mean Difference (Fixed, 95% CI)

103.20 [84.83, 121.58]

7 Mean difference in time spent standing at work, follow‐up short‐term (RCT only) Show forest plot

4

132

Mean Difference (Fixed, 95% CI)

98.65 [74.94, 122.36]

8 Mean difference in time spent stepping at work follow‐up short‐term Show forest plot

8

270

Mean Difference (Random, 95% CI)

‐0.52 [‐3.88, 2.85]

9 Mean difference in time spent standng at work, follow‐up medium‐term (CBA) Show forest plot

2

60

Mean Difference (IV, Fixed, 95% CI)

53.36 [16.59, 90.14]

10 Work performance (1‐10 scale), follow‐up short‐term (CBA) Show forest plot

3

109

Mean Difference (Fixed, 95% CI)

0.35 [‐0.10, 0.79]

10.1 Sit‐stand desk only

2

52

Mean Difference (Fixed, 95% CI)

0.82 [0.00, 1.63]

10.2 Sit‐stand desk + information and counselling

2

57

Mean Difference (Fixed, 95% CI)

0.15 [‐0.38, 0.68]

11 Proportion with ≥ 1 sick days in the last three months (CBA) Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

12 Proportion with ≥ 1 sick days in the last month (CBA) Show forest plot

2

78

Risk Ratio (M‐H, Fixed, 95% CI)

0.77 [0.49, 1.21]

12.1 Sit‐stand desk only

1

20

Risk Ratio (M‐H, Fixed, 95% CI)

0.94 [0.42, 2.13]

12.2 Sit‐stand desk + information and counselling

2

58

Risk Ratio (M‐H, Fixed, 95% CI)

0.72 [0.41, 1.24]

13 Mean difference in musculoskeletal symptoms, follow‐up short‐term Show forest plot

1

46

Mean Difference (Fixed, 95% CI)

‐0.51 [‐1.03, ‐0.00]

14 Mean difference in musculoskeletal symptoms, follow‐up Medium‐term Show forest plot

1

45

Mean Difference (Fixed, 95% CI)

‐0.54 [‐0.89, ‐0.19]

Figuras y tablas -
Comparison 1. Sit‐stand desk with or without information and counselling versus sit‐desk
Comparison 2. Standing desk versus sit‐stand desk

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

2 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Figuras y tablas -
Comparison 2. Standing desk versus sit‐stand desk
Comparison 3. Active workstation versus sit desk

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

1.1 Treadmill desk plus counselling versus sit desk

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

2 Mean difference in time spent in inactive sitting at work, follow‐up medium term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

2.1 Cycling desk + information and counselling versus information and counselling only

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

Figuras y tablas -
Comparison 3. Active workstation versus sit desk
Comparison 4. Walking strategies versus no intervention

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short term Show forest plot

1

179

Mean Difference (Fixed, 95% CI)

‐15.49 [‐49.65, 18.67]

1.1 Route versus no intervention

1

90

Mean Difference (Fixed, 95% CI)

‐16.0 [‐64.98, 32.98]

1.2 Incidental versus no intervention

1

89

Mean Difference (Fixed, 95% CI)

‐15.0 [‐62.66, 32.66]

2 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

1

264

Mean Difference (IV, Fixed, 95% CI)

‐16.50 [‐60.55, 27.55]

3 Percentage of lost work productivity (WLQ Index Score) follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Figuras y tablas -
Comparison 4. Walking strategies versus no intervention
Comparison 5. Short break versus long break

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Figuras y tablas -
Comparison 5. Short break versus long break
Comparison 6. Information, feedback and/or reminder versus information only or no intervention

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short term Show forest plot

2

63

Mean Difference (IV, Fixed, 95% CI)

‐19.23 [‐57.05, 18.58]

1.1 Information and feedback versus no intervention

2

63

Mean Difference (IV, Fixed, 95% CI)

‐19.23 [‐57.05, 18.58]

2 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

2

747

Mean Difference (Fixed, 95% CI)

‐28.38 [‐51.49, ‐5.26]

2.1 Counselling versus no intervention

2

747

Mean Difference (Fixed, 95% CI)

‐28.38 [‐51.49, ‐5.26]

3 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Subtotals only

3.1 Information and feedback versus no intervention

1

37

Mean Difference (Fixed, 95% CI)

‐16.40 [‐96.85, 64.06]

4 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Subtotals only

4.1 Counselling versus no intervention

1

416

Mean Difference (Fixed, 95% CI)

‐20.0 [‐85.00, 45.00]

5 Mean difference in time spent standing at work follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Subtotals only

5.1 Information and feedback

1

93

Mean Difference (Fixed, 95% CI)

10.24 [‐17.17, 37.65]

6 Work engagement (0‐6 scale), follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Subtotals only

6.1 Counseling versus no intervention

1

224

Mean Difference (Fixed, 95% CI)

0.1 [‐0.10, 0.30]

Figuras y tablas -
Comparison 6. Information, feedback and/or reminder versus information only or no intervention
Comparison 7. Prompts plus information versus information alone

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short term Show forest plot

2

75

Mean Difference (IV, Fixed, 95% CI)

‐10.48 [‐44.88, 23.92]

2 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

1

34

Mean Difference (Fixed, 95% CI)

‐54.92 [‐95.82, ‐14.02]

3 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

1

28

Mean Difference (Fixed, 95% CI)

‐73.92 [‐123.78, ‐24.06]

5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

6 Mean difference in time spent standing at work follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

7 Mean difference in energy expenditure, follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Figuras y tablas -
Comparison 7. Prompts plus information versus information alone
Comparison 8. Computer prompts to step versus computer prompts to stand

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

2 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

3 Mean difference in time spent standing at work, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

4 Mean difference in time spent stepping at work, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

Figuras y tablas -
Comparison 8. Computer prompts to step versus computer prompts to stand
Comparison 9. High personalised or contextualised information versus less personalised or contextualised information

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Figuras y tablas -
Comparison 9. High personalised or contextualised information versus less personalised or contextualised information
Comparison 10. Mindfulness training versus no intervention

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

1

257

Mean Difference (Fixed, 95% CI)

‐22.69 [‐62.55, 17.17]

2 Work engagement (0‐6 scale), follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Figuras y tablas -
Comparison 10. Mindfulness training versus no intervention
Comparison 11. Activity tracker combined with organisational support versus organisational support only

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

2 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

3 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up medium‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

5 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

6 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

7 Mean difference in time spent standing at work follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

8 Mean difference in time spent stepping at work, follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

9 Mean difference in time spent standing at work follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

10 Mean difference in time spent stepping at work, follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Figuras y tablas -
Comparison 11. Activity tracker combined with organisational support versus organisational support only
Comparison 12. Multi‐component intervention versus no intervention

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mean difference in time spent sitting at work, follow‐up short‐term Show forest plot

3

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

2 Mean difference in time spent sitting at work, follow‐up medium‐term Show forest plot

2

562

Mean Difference (IV, Fixed, 95% CI)

‐45.60 [‐62.54, ‐28.66]

3 Mean difference in number of sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

4 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up short‐term Show forest plot

2

Mean Difference (Fixed, 95% CI)

Totals not selected

5 Mean difference in time in sitting bouts lasting 30 minutes or more, follow‐up medium‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

6 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up short‐term Show forest plot

2

227

Mean Difference (Fixed, 95% CI)

‐72.73 [‐91.87, ‐53.59]

7 Mean difference in total time spent sitting (including sitting at and outside work), follow‐up medium‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

8 Mean difference in time spent standing at work follow‐up short‐term Show forest plot

2

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

9 Mean difference in time spent stepping at work follow‐up short‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

10 Mean difference in time spent standing at work follow‐up medium‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

11 Mean difference in time spent stepping at work follow‐up medium‐term Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

12 Work engagement (0‐6 scale), follow‐up short‐term Show forest plot

1

Mean Difference (Fixed, 95% CI)

0.0 [‐0.14, 0.14]

12.1 Environmental interventions only

1

Mean Difference (Fixed, 95% CI)

0.1 [‐0.10, 0.30]

12.2 Environmental interventions + counselling

1

Mean Difference (Fixed, 95% CI)

‐0.1 [‐0.30, 0.10]

13 Mean difference in musculoskeletal symptoms all sites (score 0–6) at short‐term follow‐up Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Figuras y tablas -
Comparison 12. Multi‐component intervention versus no intervention