Appendix 1. MEDLINE (OVID) search strategy

1. exp Taste disorders/  

2. Taste perception/                               

3. (ageusia$ or hypogeusia$ or dysgeusia$ or parageusia$).mp.                             

4. (taste adj3 (distort$ or dysfunction$ or disorder$ or alter$ or change$ or abnormal$ or blind$)).mp.                             

5. (gustatory adj3 (perception$ or sensitive$ or distort$)).mp.                            

6. or/1‐5

The above subject search was linked to the Cochrane Highly Sensitive Search Strategy (CHSSS) for identifying randomised trials in MEDLINE: sensitivity maximising version (2008 revision) as referenced in Chapter 6.4.11.1 and detailed in box 6.4.c of the Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011] (Higgins 2011).

1. randomized controlled trial.pt.
2. controlled clinical trial.pt.
3. randomized.ab.
4. placebo.ab.
5. drug therapy.fs.
6. randomly.ab.
7. trial.ab.
8. groups.ab.
9. or/1‐8
10. exp animals/ not humans.sh.
11. 9 not 10

Appendix 2. Cochrane Oral Health Group Trials Register Search Strategy

#1 ((ageusi* or hypogeusi* or dysgeusi* or parageusi*):ti,ab) AND (INREGISTER)
#2 ((taste and (distort* or dysfunction* or disorder* or alter* or change* or abnormal* or blind*)):ti,ab) AND (INREGISTER)
#3 ((gustatory and (perception* or sensitiv* or distort*)):ti,ab) AND (INREGISTER)
#4 (#1 or #2 or #3) AND (INREGISTER)

Appendix 3. Cochrane Central Register of Controlled Trials (CENTRAL) Search Strategy

#1 [mh "Taste disorders"]
#2 [mh ^"Taste perception"]
#3 (ageusi* or hypogeusi* or dysgeusi* or parageusi*)
#4 (taste near/3 (distort* or dysfunction* or disorder* or alter* or change* or abnormal* or blind*))
#5 (gustatory near/3 (perception* or sensitiv* or distort*))
#6 #1 or #2 or #3 or #4 or #5

Appendix 4. EMBASE (OVID) Search Strategy

1. Taste disorder/
2. (ageusi$ or hypogeusi$ or dysgeusi$ or parageusi$).mp.
3. (taste adj3 (distort$ or dysfunction$ or disorder$ or alter$ or change$ or abnormal$ or blind$)).mp.
4. (gustatory adj3 (perception$ or sensitiv$ or distort$)).mp.
5. or/1‐4

The above subject search was linked to the Cochrane Oral Health Group filter for identifying RCTs in EMBASE via OVID:

1. random$.ti,ab.
2. factorial$.ti,ab.
3. (cross‐over$ or cross‐over$ or cross‐over$).ti,ab.
4. placebo$.ti,ab.
5. (doubl$ adj blind$).ti,ab.
6. (singl$ adj blind$).ti,ab.
7. assign$.ti,ab.
8. allocat$.ti,ab.
9. volunteer$.ti,ab.
10. CROSS‐OVER PROCEDURE.sh.
11. DOUBLE‐BLIND PROCEDURE.sh.
12. RANDOMIZED CONTROLLED TRIAL.sh.
13. SINGLE BLIND PROCEDURE.sh.
14. or/1‐13
15. (exp animal/ or animal.hw. or nonhuman/) not (exp human/ or human cell/ or (human or humans).ti.)
16. 14 NOT 15

Appendix 5. CINAHL (EBSCO) Search Strategy

S1 (MH "Taste disorders+")
S2 TI ( (ageusi* or hypogeusi* or dysgeusi* or parageusi*) ) OR AB ( (ageusi* or hypogeusi* or dysgeusi* or parageusi*))
S3 TI ( (taste N3 (distort* or dysfunction* or disorder* or alter* or change* or abnormal* or blind*)) ) OR AB ( (taste N3 (distort* or dysfunction* or disorder* or alter* or change* or abnormal* or blind*)))
S4 TI ( (gustatory N3 (perception* or sensitiv* or distort*)) ) OR AB ( (gustatory N3 (perception* or sensitiv* or distort*)))
S5 S1 or S2 or S3 or S4

The above subject search was linked to the Cochrane Oral Health Group filter for identifying RCTs in CINAHL via EBSCO:

S1 MH Random Assignment or MH Single‐blind Studies or MH Double‐blind Studies or MH Triple‐blind Studies or MH Cross‐over design or MH Factorial Design
S2 TI ("multicentre study" or "multicenter study" or "multi‐centre study" or "multi‐center study") or AB ("multicentre study" or "multicenter study" or "multi‐centre study" or "multi‐center study") or SU ("multicentre study" or "multicenter study" or "multi‐centre study" or "multi‐center study")
S3 TI random* or AB random*
S4 AB "latin square" or TI "latin square"
S5 TI (crossover or cross‐over) or AB (crossover or cross‐over) or SU (crossover or cross‐over)
S6 MH Placebos
S7 AB (singl* or doubl* or trebl* or tripl*) or TI (singl* or doubl* or trebl* or tripl*)
S8 TI blind* or AB mask* or AB blind* or TI mask*
S9 S7 and S8
S10 TI Placebo* or AB Placebo* or SU Placebo*
S11 MH Clinical Trials
S12 TI (Clinical AND Trial) or AB (Clinical AND Trial) or SU (Clinical AND Trial)
S13 S1 or S2 or S3 or S4 or S5 or S6 or S9 or S10 or S11 or S12

Appendix 6. AMED (OVID) Search Strategy

1. Taste disorders/
2. (ageusi$ or hypogeusi$ or dysgeusi$ or parageusi$).mp.
3. (taste adj3 (distort$ or dysfunction$ or disorder$ or alter$ or change$ or abnormal$ or blind$)).mp.
4. (gustatory adj3 (perception$ or sensitiv$ or distort$)).mp.
5. or/1‐4

Appendix 7. US National Institutes of Health Trials Registry Search Strategy

Condition = Taste disorder
Condition = Taste disturbance

Appendix 8. metaRegister of Controlled Trials Search Strategy

taste AND disorder
taste AND disturbance

Appendix 9. WHO International Clinical Trials Registry Search Strategy

taste disorder
taste disturbance

Appendix 10. International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) Clinical Trials Portal Search Strategy

taste disorder
taste disturbance

Appendix 11. International Association of Dental Research (IADR) Conference Abstracts

taste disorder

dysgeusia

Appendix 12. Association for the Research in Otolaryngology Conference Proceedings

taste disorder

dysgeusia