Appendix 1. MDSG search strategy

Menstrual Disorders and Subfertility Group (MDSG) specialised register search for SFR1820 04.07.12

Keywords CONTAINS "Polycystic Ovary Syndrome"or "PCOS"or "*Ovulation Induction"or"ovulation stimulation"or "ovarian hyperstimulation"or"superovulation"or Title CONTAINS"Polycystic Ovary Syndrome"or "PCOS"or "*Ovulation Induction"or"ovulation stimulation"or "ovarian hyperstimulation"or"superovulation"

AND

Keywords CONTAINS "aromatase inhibition"or"aromatase inhibitor" or "aromatase P450" or "Anastrozole" or "letozole" or "letrozole" or "Exemestane" or "arimidex" or Title CONTAINS  "aromatase inhibition"or"aromatase inhibitor" or "aromatase P450" or "Anastrozole" or "letozole" or "letrozole" or "Exemestane" or "arimidex"

Appendix 2. CENTRAL search strategy

Database: EBM Reviews ‐ Cochrane Central Register of Controlled Trials <June 2012>
Search Strategy:

1 exp Polycystic Ovary Syndrome/
2 Polycystic Ovar$.tw.
3 PCOS.tw.
4 PCOD.tw.
5 stein leventh$.tw.
6 (ovar$ adj2 sclerocystic).tw.
7 (ovar$ adj2 degeneration).tw.
8 PCO.tw.
9 exp ovulation induction/ or exp superovulation/
10 (ovulat$ adj2 induc$).tw.
11 superovulation.tw.
12 (ovari$ adj2 hyperstimulat$).tw.
13 (ovari$ adj2 stimulat$).tw.
14 or/1‐13
15 exp aromatase inhibitors/ or exp aminoglutethimide/ or exp fadrozole/
16 aromatase inhibitor$.tw.
17 aminoglutethimide.tw.
18 Anastrozole.tw.
19 Arimidex.tw.
20 Letrozole.tw.
21 Femara.tw.
22 Exemestane.tw.
23 Aromasin.tw.
24 Vorozole.tw.
25 Rivizor.tw.
26 Formestane.tw.
27 Lentaron.tw.
28 Fadrozole.tw.
29 Afema.tw.
30 or/15‐29
31 14 and 30

Appendix 3. MEDLINE search strategy

Database: Ovid MEDLINE(R) In‐Process & Other Non‐Indexed Citations, Ovid MEDLINE(R) Daily and Ovid MEDLINE(R) <1946 to Present>
Search Strategy:

1 exp Polycystic Ovary Syndrome/
2 Polycystic Ovar$.tw.
3 PCOS.tw.
4 PCOD.tw.
5 stein leventh$.tw.
6 (ovar$ adj2 sclerocystic).tw.
7 (ovar$ adj2 degeneration).tw.
8 PCO.tw.
9 exp ovulation induction/ or exp superovulation/
10 (ovulat$ adj2 induc$).tw.
11 superovulation.tw.
12 (ovari$ adj2 hyperstimulat$).tw.
13 (ovari$ adj2 stimulat$).tw.
14 or/1‐13
15 exp aromatase inhibitors/ or exp aminoglutethimide/ or exp fadrozole/
16 aromatase inhibitor$.tw.
17 aminoglutethimide.tw.
18 Anastrozole.tw.
19 Arimidex.tw.
20 Letrozole.tw.
21 Femara.tw.
22 Exemestane.tw.
23 Aromasin.tw.
24 Vorozole.tw.
25 Rivizor.tw.
26 Formestane.tw.
27 Lentaron.tw.
28 Fadrozole.tw.
29 Afema.tw.
30 or/15‐29
31 14 and 30
32 randomized controlled trial.pt.
33 controlled clinical trial.pt.
34 randomized.ab.
35 placebo.tw.
36 clinical trials as topic.sh.
37 randomly.ab.
38 trial.ti.
39 (crossover or cross‐over or cross over).tw.
40 or/32‐39
41 exp animals/ not humans.sh.
42 40 not 41
43 31 and 42

Appendix 4. EMBASE search strategy

Database: Embase <1980 to 2012 Week 26>
Search Strategy:

1 exp ovary polycystic disease/
2 Polycystic Ovar$.tw.
3 PCOS.tw.
4 PCOD.tw.
5 stein leventh$.tw.
6 (ovar$ adj2 sclerocystic).tw.
7 (ovar$ adj2 degeneration).tw.
8 PCO.tw.
9 exp ovulation induction/
10 (ovulat$ adj2 induc$).tw.
11 (ovari$ adj2 hyperstimulat$).tw.
12 superovulation.tw.
13 (ovari$ adj2 stimulat$).tw.
14 or/1‐13
15 exp aromatase inhibitor/
16 aromatase inhibitor$.tw.
17 aminoglutethimide.tw.
18 Anastrozole.tw.
19 Arimidex.tw.
20 Letrozole.tw.
21 Femara.tw.
22 Exemestane.tw.
23 Aromasin.tw.
24 Vorozole.tw.
25 Rivizor.tw.
26 Formestane.tw.
27 Lentaron.tw.
28 Fadrozole.tw.
29 Afema.tw.
30 or/15‐29
31 14 and 30
32 Clinical Trial/
33 Randomized Controlled Trial/
34 exp randomization/
35 Single Blind Procedure/
36 Double Blind Procedure/
37 Crossover Procedure/
38 Placebo/
39 Randomi?ed controlled trial$.tw.
40 Rct.tw.
41 random allocation.tw.
42 randomly allocated.tw.
43 allocated randomly.tw.
44 (allocated adj2 random).tw.
45 Single blind$.tw.
46 Double blind$.tw.
47 ((treble or triple) adj blind$).tw.
48 placebo$.tw.
49 prospective study/
50 or/32‐49
51 case study/
52 case report.tw.
53 abstract report/ or letter/
54 or/51‐53
55 50 not 54
56 31 and 55

Appendix 5. PSYCINFO search strategy

Database: PsycINFO <1806 to June Week 4 2012>
Search Strategy:

1 exp Endocrine Sexual Disorders/
2 Polycystic Ovar$.tw.
3 PCOS.tw.
4 PCOD.tw.
5 or/1‐4
6 aromatase inhibitor$.tw.
7 Anastrozole.tw.
8 Arimidex.tw.
9 Letrozole.tw.
10 Femara.tw.
11 Exemestane.tw.
12 or/6‐11
13 5 and 12