Berufliche Rehabilitation um unter Arbeitnehmern mit traumatischen Verletzungen der oberen Extremität die Wiederaufnahme der Erwerbstätigkeit zu verbessern
Appendices
Appendix 1. CENTRAL search strategy and results
Database CENTRAL
Date Run: 3 September 2017 (YYC)
| ID | Search |
| #1 | MeSH descriptor: [Hand Injuries] explode all trees |
| #2 | "hand injury" or "hands injury" or "hand injur*" or "hands injur*" :ti,ab,kw (Word variations have been searched) |
| #3 | MeSH descriptor: [Tendon Injuries] explode all trees |
| #4 | "tendon injury" or "tendon injur*":ti,ab,kw (Word variations have been searched) |
| #5 | MeSH descriptor: [Forearm Injuries] explode all trees |
| #6 | "forearm injury" or "forearm injur*" or "forearms injur*":ti,ab,kw (Word variations have been searched) |
| #7 | MeSH descriptor: [Wrist Injuries] explode all trees |
| #8 | "wrist injuries" or "wrist injury" or "wrist injur*" or "wrists injur*":ti,ab,kw (Word variations have been searched) |
| #9 | MeSH descriptor: [Humeral Fractures] explode all trees |
| #10 | "humeral fracture" or "humeral fractures" or "humeral fractur*" or "humerus fracture" or "humerus fractur*" or "humeri fracture" or "humeri fractur*":ti,ab,kw (Word variations have been searched) |
| #11 | MeSH descriptor: [Shoulder Fractures] explode all trees |
| #12 | "shoulder fractur*" or "brachium fractur*" or "brachial fractur*":ti,ab,kw (Word variations have been searched) |
| #13 | MeSH descriptor: [Radius Fractures] explode all trees |
| #14 | "radius fractur*" or "radii fractur*":ti,ab,kw (Word variations have been searched) |
| #15 | MeSH descriptor: [Ulna Fractures] explode all trees |
| #16 | MeSH descriptor: [Upper Extremity] explode all trees |
| #17 | "ulna fractur*":ti,ab,kw (Word variations have been searched) |
| #18 | injur* and #16:ti,ab,kw (Word variations have been searched) |
| #19 | "upper extremity injury" or "upper extremity injur*":ti,ab,kw (Word variations have been searched) |
| #20 | MeSH descriptor: [Finger Injuries] explode all trees |
| #21 | "finger injur*" or "digit injur*":ti,ab,kw (Word variations have been searched) |
| #22 | #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 or #14 or #15 or #17 or #18 or #19 or #20 or #21 |
| #23 | MeSH descriptor: [Occupational Medicine] explode all trees |
| #24 | #23 or "occupational medicine":ti,ab,kw (Word variations have been searched) |
| #25 | MeSH descriptor: [Occupational Health] explode all trees |
| #26 | #25 or "occupational health":ti,ab,kw (Word variations have been searched) |
| #27 | MeSH descriptor: [Occupational Health Services] explode all trees |
| #28 | #27 or "occupational health service*":ti,ab,kw (Word variations have been searched) |
| #29 | MeSH descriptor: [Rehabilitation] explode all trees |
| #30 | #29 or "rehabilitation":ti,ab,kw (Word variations have been searched) |
| #31 | MeSH descriptor: [Employment] explode all trees |
| #32 | #31 or "employment":ti,ab,kw (Word variations have been searched) |
| #33 | MeSH descriptor: [Work] explode all trees |
| #34 | #33 or "working":ti,ab,kw (Word variations have been searched) |
| #35 | [Education] explode all trees |
| #36 | [Educational Status] explode all trees |
| #37 | #35 or #36 or "education":ti,ab,kw (Word variations have been searched) |
| #38 | #24 or #26 or #28 or #30 or #32 or #34 or #37 |
| #39 | [Rehabilitation, Vocational] explode all trees |
| #40 | [Counseling] explode all trees |
| #41 | [Vocational Guidance] explode all trees |
| #42 | "work rehabilitation":ti,ab,kw (Word variations have been searched) |
| #43 | vocational*:ti,ab,kw (Word variations have been searched) |
| #44 | "counseling*" or "counsell*":ti,ab,kw (Word variations have been searched) |
| #45 | "training*":ti,ab,kw (Word variations have been searched) |
| #46 | "occupational rehabilitation*":ti,ab,kw (Word variations have been searched) |
| #47 | "workplace intervention*":ti,ab,kw (Word variations have been searched) |
| #48 | "workplace accomodation*":ti,ab,kw (Word variations have been searched) |
| #49 | "workplace adjustment*":ti,ab,kw (Word variations have been searched) |
| #50 | "modified‐duty" or "modified‐duties" or "modified work*":ti,ab,kw (Word variations have been searched) |
| #51 | "case manager*":ti,ab,kw (Word variations have been searched) |
| #52 | "work reintegration*":ti,ab,kw (Word variations have been searched) |
| #53 | "work‐site‐visit*" or "work site visit":ti,ab,kw (Word variations have been searched) |
| #54 | "workplace vocational*":ti,ab,kw (Word variations have been searched) |
| #55 | #54 or "vocational workplace*":ti,ab,kw (Word variations have been searched) |
| #56 | #39 or #40 or #41 or #42 or #43 or #44 or #45 or #46 or #47 or #49 or #50 or #51 or #52 or #53 or #55 |
| #57 | MeSH descriptor: [Absenteeism] explode all trees |
| #58 | #57 or "absenteeism*":ti,ab,kw (Word variations have been searched) |
| #59 | MeSH descriptor: [Sick Leave] explode all trees |
| #60 | #59 or "sick leave*" or "sickness leave*" or "sickness absence*":ti,ab,kw (Word variations have been searched) |
| #61 | #58 or #60 |
| #62 | "return‐to‐work" or "return to work":ti,ab,kw (Word variations have been searched) |
| #63 | MeSH descriptor: [Unemployment] explode all trees |
| #64 | #63 or "unemployment" or "unemployed":ti,ab,kw (Word variations have been searched) |
| #65 | "employability" or "employable" or "employee*":ti,ab,kw (Word variations have been searched) |
| #66 | #62 or #64 or #65 |
| #67 | "disability management":ti,ab,kw (Word variations have been searched) |
| #68 | "work ability" or "work activity":ti,ab,kw (Word variations have been searched) |
| #69 | "work disability" or "work disabilities":ti,ab,kw (Word variations have been searched) |
| #70 | "work status":ti,ab,kw (Word variations have been searched) |
| #71 | "work retention" or "job retention":ti,ab,kw (Word variations have been searched) |
| #72 | "workability":ti,ab,kw (Word variations have been searched) |
| #73 | #67 or #68 or #69 or #70 or #71 or #72 |
| #74 | #38 or #56 |
| #75 | #61 or #66 or #73 |
| #76 | #22 and #74 and #75 (Trials) |
Appendix 2. MEDLINE search strategy and results
Database: MEDLINE
Date run: 30 August 2017 (YYC)
| ID | Search |
| #1 | hand injury |
| #2 | tendon injury |
| #3 | forearm injury |
| #4 | wrist injury |
| #5 | humeral fractures |
| #6 | humeri fracture |
| #7 | humeri fractures |
| #8 | shoulder fractures |
| #9 | shoulder fracture |
| #10 | brachium fracture |
| #11 | brachium fractures |
| #12 | brachial fracture |
| #13 | brachial fractures |
| #14 | radius fracture |
| #15 | radius fractures |
| #16 | radii fractures |
| #17 | radii fracture |
| #18 | ulna fracture |
| #19 | ulna fractures |
| #20 | Upper extremity injury |
| #21 | Upper extremity injuries |
| #22 | finger injury |
| #23 | fingers injury |
| #24 | fingers injuries |
| #25 | digit injury |
| #26 | digit injuries |
| #27 | #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23 OR #24 OR #25 OR#26 |
| #28 | occupational medicine |
| #29 | occupational health |
| #30 | occupational health service |
| #31 | occupational health services |
| #32 | rehabilitation |
| #33 | employment |
| #34 | work |
| #35 | education |
| #36 | education status |
| #37 | vocational rehabilitation |
| #38 | counseling |
| #39 | vocational guidance |
| #40 | work rehabilitation |
| #41 | training |
| #42 | occupational rehabilitation |
| #43 | workplace intervention |
| #44 | workplace interventions |
| #45 | workplace accommodation |
| #46 | workplace adjustment |
| #47 | modify duty |
| #48 | modify duties |
| #49 | modify work |
| #50 | modify works |
| #51 | case manager |
| #52 | case managers |
| #53 | work reintegration |
| #54 | work‐site‐visit |
| #55 | workplace vocational |
| #56 | #28 OR #29 OR #30 OR #31 OR #32 OR #33 OR #34 OR #35 OR #36 OR #37 OR #38 OR #39 OR #40 OR #41 OR #42 OR #43 OR #44 OR #45 OR #46 OR #47 OR #48 OR #49 OR #50 OR #51 OR #52 OR #53 OR #54 OR #55 |
| #57 | #27 AND #56 |
| #58 | absenteeism |
| #59 | sick leave |
| #60 | sickness leave |
| #61 | sickness absence |
| #62 | return to work |
| #63 | unemployed |
| #64 | employable |
| #65 | employee |
| #66 | disability management |
| #67 | work ability |
| #68 | work activity |
| #69 | work activities |
| #70 | work disability |
| #71 | work disabilities |
| #72 | work status |
| #73 | work retention |
| #74 | job retention |
| #75 | #58 OR #59 OR #60 OR #61 OR #62 OR #63 OR #64 OR #65 OR #66 OR #67 OR #68 OR #69 OR #70 OR #71 OR #72 OR #73 OR #74 |
| #76 | #75 AND #57 |
| #77 | Limit RCT OR Controlled clinical trial |
| #78 | Limit Human |
Appendix 3. EMBASE search strategy and results
Database: EMBASE
Date run: 3 September 2017 (YYC)
| ID | Search |
| #1 | 'hand injury'/exp OR 'hand injury' |
| #2 | 'tendon injury'/exp OR 'tendon injury' |
| #3 | 'arm injury'/exp OR 'arm injury' |
| #4 | 'wrist injury'/exp OR 'wrist injury' |
| #5 | 'humerus fracture'/exp OR 'humerus fracture' |
| #6 | 'shoulder fracture'/exp OR 'shoulder fracture' |
| #7 | 'radius fracture'/exp OR 'radius fracture' |
| #8 | 'ulna fracture'/exp OR 'ulna fracture' |
| #9 | 'hand'/exp OR hands OR hand |
| #10 | 'injury'/exp OR injur* |
| #11 | #9 AND #10 |
| #12 | 'tendon'/exp OR tendon |
| #13 | #12 AND #10 |
| #14 | arm'/exp OR arm OR arms |
| #15 | #14 AND #10 |
| #16 | 'wrist'/exp OR wrist OR wrists |
| #17 | #16 AND #10 |
| #18 | humerus'/exp OR humerus |
| #19 | fracture'/exp OR fracture |
| #20 | #18 AND #19 |
| #21 | 'shoulder'/exp OR shoulder OR shoulders |
| #22 | #21 AND #19 |
| #23 | brachium |
| #24 | brachial |
| #25 | #23 OR #24 |
| #26 | #25 AND #19 |
| #27 | radius'/exp OR radius |
| #28 | #27 AND #19 |
| #29 | ulna'/exp OR ulna |
| #30 | #29 AND #19 |
| #31 | #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #11 OR #13 OR #15 OR #17 OR #20 OR #22 OR #25 OR #26 OR #28 OR #30 |
| #32 | 'occupational medicine'/exp OR 'occupational medicine' |
| #33 | 'occupational health'/exp OR 'occupational health' |
| #34 | 'occupational health service'/exp OR 'occupational health service' |
| #35 | 'rehabilitation'/exp OR rehabilitation |
| #36 | 'employment'/exp OR employment |
| #37 | 'work'/exp OR work |
| #38 | 'education'/exp OR educat* |
| #39 | 'educational status'/exp OR 'educational status' |
| #40 | #32 OR #33 OR #34 OR #35 OR #36 OR #37 OR #38 OR #39 |
| #47 | 'disability'/exp OR disability |
| #48 | 'management'/exp OR management |
| #49 | #47 AND #48 |
| #50 | 'work'/exp OR work AND ('ability'/exp OR ability) OR workability |
| #51 | 'work'/exp OR work AND ('disability'/exp OR disability) |
| #52 | 'work'/exp OR work AND activity |
| #53 | 'work'/exp OR work AND retention OR 'job'/exp OR job AND retention |
| #54 | 'work'/exp OR work AND status |
| #55 | #47 OR #48 OR #49 OR #50 OR #51 OR #52 OR #53 OR #54 |
| #56 | #31 AND #40 AND #55 |
| #57 | #56 AND ('clinical trial'/de OR 'controlled study'/de OR 'randomized controlled trial'/de) |
| #58 | #57 AND ('clinical trial'/de OR 'controlled study'/de OR 'randomized controlled trial'/de) AND [embase]/lim NOT [medline]/lim |
| #59 | #58 AND ('clinical trial'/de OR 'controlled study'/de OR 'randomized controlled trial'/de) AND [embase]/lim NOT [medline]/lim AND [humans]/lim |
Appendix 4. CINAHL search strategy and results
Database: CINAHL
Data run: 6 September 2017 (YYC)
| ID | Search |
| S1 | hand injuries |
| S2 | hand injur* |
| S3 | hands injur* |
| S4 | tendon injuries |
| S5 | tendon injur* |
| S6 | forearm injuries |
| S7 | forearm injur* |
| S8 | forearms injur* |
| S9 | wrist injuries |
| S10 | wrists injur* |
| S11 | wrist injur* |
| S12 | humeral fractures |
| S13 | humeral fractur* |
| S14 | humerus fractur* |
| S15 | brachium fractur* |
| S16 | brachial fractur* |
| S17 | wrist fractures |
| S18 | wrists fractur* |
| S19 | radius fractures |
| S20 | ulna fractures |
| S21 | ulna fractur* |
| S22 | upper extremity |
| S23 | upper extremity injur* |
| S24 | finger injuries |
| S25 | finger injur* |
| S26 | fingers injur* |
| S27 | digit injur* |
| S28 | arm injuries |
| S29 | arms injur* |
| S30 | arm injur* |
| S31 | elbow fractures |
| S32 | elbow fractur* |
| S33 | elbows fractur* |
| S35 | elbow injuries |
| S34 | elbow injur* |
| S36 | elbows injur* |
| S37 | S1 OR ˜ S36 |
| S38 | Occupational Medicine |
| S39 | Occupational Medicine |
| S40 | Occupational Health Nursing |
| S41 | Occupational Health Nursing |
| S42 | Work Environment |
| S43 | Work Environment |
| S44 | Rehabilitation, Vocational |
| S45 | Vocational Rehabilitation |
| S46 | Occupational health |
| S47 | Occupational health |
| S48 | Occupational health services |
| S49 | Occupational health service* |
| S50 | rehabilitation |
| S51 | rehabilitation |
| S52 | Occupational rehabilitation |
| S53 | workplace rehabilitation |
| S54 | training |
| S55 | counseling |
| S56 | counseling |
| S57 | counselling |
| S58 | job accommodation |
| S59 | job accommodation |
| S60 | workplace accommodation |
| S61 | S38 OR ˜ S60 |
| S62 | S61 AND S37 |
| S63 | return to work |
| S64 | return‐to‐work |
| S65 | unemployment |
| S66 | unemployment |
| S67 | employment of disable |
| S68 | employment of disabled |
| S69 | absenteeism |
| S70 | absenteeism* |
| S71 | employability |
| S72 | employable |
| S73 | employee* |
| S74 | work ability |
| S75 | work activity |
| S76 | work disabilit* |
| S77 | sick leave |
| S78 | sick leave |
| S79 | S63 OR˜S78 |
| S80 | S79 AND S62 |
| S81 | Limit RCT |
Appendix 5. PsycINFO search strategy and results
Database: PsycINFO
Date run: 6 September 2017 (YYC)
| ID | Search |
| S1 | hand injuries |
| S2 | hand injur* |
| S3 | hands injur* |
| S4 | tendon injuries |
| S5 | tendon injur* |
| S6 | forearm injuries |
| S7 | forearm injur* |
| S8 | forearms injur* |
| S9 | wrist injuries |
| S10 | wrists injur* |
| S11 | wrist injur* |
| S12 | humeral fractures |
| S13 | humeral fractur* |
| S14 | humerus fractur* |
| S15 | brachium fractur* |
| S16 | brachial fractur* |
| S17 | wrist fractures |
| S18 | wrists fractur* |
| S19 | radius fractures |
| S20 | ulna fractures |
| S21 | ulna fractur* |
| S22 | upper extremity |
| S23 | upper extremity injur* |
| S24 | finger injuries |
| S25 | finger injur* |
| S26 | fingers injur* |
| S27 | digit injur* |
| S28 | arm injuries |
| S29 | arms injur* |
| S30 | arm injur* |
| S31 | elbow fractures |
| S32 | elbow fractur* |
| S33 | elbows fractur* |
| S35 | elbow injuries |
| S34 | elbow injur* |
| S36 | elbows injur* |
| S37 | S1 OR ˜ S36 |
| S38 | Occupational Medicine |
| S39 | Occupational Medicine |
| S40 | Occupational Health Nursing |
| S41 | Occupational Health Nursing |
| S42 | Work Environment |
| S43 | Work Environment |
| S44 | Rehabilitation, Vocational |
| S45 | Vocational Rehabilitation |
| S46 | Occupational health |
| S47 | Occupational health |
| S48 | Occupational health services |
| S49 | Occupational health service* |
| S50 | rehabilitation |
| S51 | rehabilitation |
| S52 | Occupational rehabilitation |
| S53 | workplace rehabilitation |
| S54 | training |
| S55 | counseling |
| S56 | counseling |
| S57 | counselling |
| S58 | job accommodation |
| S59 | job accommodation |
| S60 | workplace accommodation |
| S61 | S38 OR ˜ S60 |
| S62 | S61 AND S37 |
| S63 | return to work |
| S64 | return‐to‐work |
| S65 | unemployment |
| S66 | unemployment |
| S67 | employment of disable |
| S68 | employment of disabled |
| S69 | absenteeism |
| S70 | absenteeism* |
| S71 | employability |
| S72 | employable |
| S73 | employee* |
| S74 | work ability |
| S75 | work activity |
| S76 | work disabilit* |
| S77 | sick leave |
| S78 | sick leave |
| S79 | S63 OR˜S78 |
| S80 | S79 AND S62 |
| S81 | Limit RCT |
Appendix 6. Risk of bias assessment
1. Was the allocation sequence randomly generated?
Yes, low risk of bias
The investigators describe a random component in the sequence generation process such as: referring to a random number table; using a computer random number generator; coin tossing; shuffling cards or envelopes; throwing dice; drawing of lots.
No, high risk of bias
The investigators describe a non‐random component in the sequence generation process. Usually, the description would involve some systematic, non‐random approach, for example: sequence generated by odd or even date of birth; sequence generated by some rule based on date (or day) of admission; sequence generated by some rule based on hospital or clinic record number.
Unclear
Insufficient information about the sequence generation process to permit judgement of 'yes' or 'no'.
2. Was the treatment allocation adequately concealed?
Yes, low risk of bias
Participants and investigators enrolling participants could not foresee assignment because one of the following, or an equivalent method, was used to conceal allocation: central allocation (including telephone, web‐based and pharmacy‐controlled randomisation); sequentially numbered drug containers of identical appearance; sequentially numbered, opaque, sealed envelopes.
No, high risk of bias
Participants or investigators enrolling participants could possibly foresee assignments and thus introduce selection bias, such as allocation based on: using an open random allocation schedule (e.g. a list of random numbers); assignment envelopes were used without appropriate safeguards (e.g. if envelopes were unsealed or nonopaque or not sequentially numbered); alternation or rotation; date of birth; case record number; any other explicitly unconcealed procedure.
Unclear
Insufficient information to permit judgment of 'yes' or 'no'. This is usually the case if the method of concealment is not described or not described in sufficient detail to allow a definite judgment, for example if the use of assignment envelopes is described, but it remains unclear whether envelopes were sequentially numbered, opaque and sealed.
3. Blinding ‐ was knowledge of the allocated interventions adequately prevented during the study?
Yes, low risk of bias
Any one of the following.
-
No blinding, but the review authors judge that the outcome and the outcome measurement are not likely to be influenced by lack of blinding.
-
Blinding of participants and key study personnel ensured, and unlikely that the blinding could have been broken.
-
Either participants or some key study personnel were not blinded, but outcome assessment was blinded and the non‐blinding of others unlikely to introduce bias.
No, high risk of bias
Any one of the following.
-
No blinding or incomplete blinding, and the outcome or outcome measurement is likely to be influenced by lack of blinding.
-
Blinding of key study participants and personnel attempted, but likely that the blinding could have been broken.
-
Either participants or some key study personnel were not blinded, and the non‐blinding of others likely to introduce bias.
Unclear
Any one of the following.
-
Insufficient information to permit judgement of 'yes' or 'no'.
-
The study did not address this outcome.
4. Were incomplete outcome data adequately addressed?
Yes, low risk of bias
Any one of the following.
-
No missing outcome data.
-
Reasons for missing outcome data unlikely to be related to true outcome (for survival data, censoring unlikely to be introducing bias).
-
Missing outcome data balanced in numbers across intervention groups, with similar reasons for missing data across groups.
-
For dichotomous outcome data, the proportion of missing outcomes compared with observed event risk not enough to have a clinically relevant impact on the intervention effect estimate.
-
For continuous outcome data, plausible effect size (difference in means or standardised difference in means) among missing outcomes not enough to have a clinically relevant impact on observed effect size.
-
Missing data have been imputed using appropriate methods.
No, high risk of bias
Any one of the following.
-
Reason for missing outcome data likely to be related to true outcome, with either imbalance in numbers or reasons for missing data across intervention groups.
-
For dichotomous outcome data, the proportion of missing outcomes compared with observed event risk enough to induce clinically relevant bias in intervention effect estimate.
-
For continuous outcome data, plausible effect size (difference in means or standardised difference in means) among missing outcomes enough to induce clinically relevant bias in observed effect size.
-
'As‐treated' analysis done with substantial departure of the intervention received from that assigned at randomisation.
-
Potentially inappropriate application of simple imputation.
Unclear
Any one of the following.
-
Insufficient reporting of attrition/exclusions to permit judgement of 'yes' or 'no' (e.g. number randomised not stated, no reasons for missing data provided).
-
The study did not address this outcome.
5. Are reports of the study free of suggestion of selective outcome reporting?
Yes, low risk of bias
Any of the following.
-
The study protocol is available and all of the study's pre‐specified (primary and secondary) outcomes that are of interest in the review have been reported in the pre‐specified way.
-
The study protocol is not available but it is clear that the published reports include all expected outcomes, including those that were pre‐specified (convincing text of this nature may be uncommon).
No, high risk of bias
Any one of the following.
-
Not all of the study's pre‐specified primary outcomes have been reported.
-
One or more primary outcomes is reported using measurements, analysis methods or subsets of the data (e.g. subscales) that were not pre‐specified.
-
One or more reported primary outcomes were not pre‐specified (unless clear justification for their reporting is provided, such as an unexpected adverse effect).
-
One or more outcomes of interest in the review are reported incompletely so that they cannot be entered in a meta‐analysis.
-
The study report fails to include results for a key outcome that would be expected to have been reported for such a study.
Unclear
Insufficient information to permit judgement of 'yes' or 'no'. It is likely that most studies will fall into this category.
6. Other sources of potential bias
Yes, low risk of bias
The study appears to be free of other sources of bias.
No, high risk of bias
There is at least one important risk of bias. For example, the study:
-
had a potential source of bias related to the specific study design used;
-
stopped early due to some data‐dependent process (including a formal‐stopping rule);
-
had extreme baseline imbalance;
-
has been claimed to have been fraudulent;
-
had some other problem.
Unclear
There may be a risk of bias, but there is either:
-
insufficient information to assess whether an important risk of bias exists; or
-
insufficient rationale or evidence that an identified problem will introduce bias.
PRISMA study flow diagram.
