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比较家庭或寄养家庭护理与机构长期护理对功能障碍的老年人的影响

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Referencias

References to studies included in this review

Braun 1987 {published data only}

Braun KL, Rose CL. Geriatric patient outcomes and costs in three settings: nursing home, foster family, and own home. Journal of the American Geriatrics Society 1987;35(5):387‐97. CENTRAL

Braun 1991 {published data only}

Braun KL, Rose CL, Finch MD. Patient characteristics and outcomes in institutional and community long term care. Gerontologist 1991;31(5):648‐56. CENTRAL

Challis 1991 {published data only}

Challis D, Darton R, Johnson L, et al. An evaluation of an alternative to long stay hospital care for frail elderly patients: II Costs and effectiveness. Age and Ageing 1991;20(4):245‐54. CENTRAL

Chuang 2005 {published data only}

Chuang KY, Wu SC, Yeh MC, et al. Exploring the associations between long term care and mortality rates among stroke patients. Journal of Nursing Research 2005;13(1):66‐73. CENTRAL

Condelius 2010 {published data only}

Condelius A, Hallberg IR, Jakobsson U. Medical healthcare utilization as related to long term care at home or in special accomodation. Archives of Gerontology and Geriatrics 2010;51(2):250‐6. CENTRAL

Mitchell 1978 {published data only}

Mitchell JB. Patient outcomes in alternative long term care settings. Medical Care 1978;16(6):439‐52. CENTRAL

Oktay 1987 {published data only}

Oktay JS, Volland PJ. Foster home care for the frail elderly as an alternative to nursing home care: an experimental evaluation. American Journal of Public Health 1987;77(12):1505‐10. CENTRAL

Sherwood 1986 {published data only}

Sherwood S, Morris JN, Ruchlin HS. Alternative paths to long term care: nursing home, geriatric day hospital, senior centre, and domiciliary care options. American Journal of Public Health 1986;76(1):38‐44. CENTRAL

Wilson 2005 {published data only}

Wilson D, Truman C. Comparing the health service utilization of long term care residents, home care recipients, and the well elderly. Canadian Journal of Nursing Research 2005;37(4):138‐54. CENTRAL

Wysocki 2014 {published data only}

Wysocki A, Kane RL, Dowd B, Golberstein E, Lum T, Shippee T. Hospitalization of elderly Medicaid long‐term care users who transition from nursing homes. Journal of the American Geriatrics Society 2014;62(1):71‐8. CENTRAL

References to studies excluded from this review

Anstey 2007 {published data only}

Anstey KJ, Von Sanden C, Sargent‐Cox K, Luszcz M. Prevalence and risk factors for depression in a longitudinal, population based study including individuals in the community and residential care. American Journal of Psychiatry 2007;15:497‐505. CENTRAL

Beerens 2014 {published data only}

Beerens HC, Sutcliffe C, Renom‐Guiteras A, Soto ME, Suhonen R, Zabalegui A, et al. RightTimePlaceCare Consortium. Quality of life and Quality of care for people with dementia receiving long term institutional care or professional home care: the European RightTimePlaceCare Study. Journal of the American Medical Directors Association 2014;15:54‐61. CENTRAL

Boggatz 2009 {published data only}

Boggatz T, Farid T, Mohammedin A, Dassen T. Factors related to the acceptance of home care and nursing homes among older Egyptians: a cross‐sectional study. International Journal of Nursing Studies 2009;46:1585‐94. CENTRAL

Bowling 1991 {published data only}

Bowling A, Formby J, Grant K, Ebrahim S. A randomised controlled trial of nursing home and long term stay geriatric ward care for elderly people. Age and Aging 1991;20:316‐24. CENTRAL

Boyle 2004 {published data only}

Boyle G. Facilitating choice and control for older people in long term care. Health and Social Care in the Community 2004;12:212‐20. CENTRAL

Brajkovic 2009 {published data only}

Brajkovic L, Godan A, Godan L. Quality of life after stroke in old age: comparison of persons living in nursing home and those living in their own home. Croatian Medical Journal 2009;50:182‐8. CENTRAL

Brennan 2003 {published data only}

Brennan J, Johansen A, Butler J, Stone M, Richmond P, Jones S, et al. Place of residence and risk of fracture in older people: a population‐based study of over 65‐year‐olds in Cardiff. Osteoporosis International 2003;14:515‐9. CENTRAL

Chappell 2004 {published data only}

Chappell NL, Dlitt BH, Hollander MJ, Miller JA, McWilliam C. Comparative costs of home care and residential care. Gerontologist 2004;44:389‐400. CENTRAL

Davis 2005 {published data only}

Davis LA, Hoppes S, Chesbro SR. Cognitive‐communicative and independent living skills assessment in individuals with dementia ‐ a pilot study of environmental impact. Topics in Geriatric Rehabilitation 2005;21:136‐43. CENTRAL

Hasson 2011 {published data only}

Hasson H, Arnetz JE. Care recipients and family members perceptions of quality of older people care: a comparison of home based care and nursing homes. Journal of Clinical Nursing 2011;20:1423‐35. CENTRAL

Hollander 2007 {published data only}

Hollander MJ, Chappell NL. A comparative analysis of costs to government for home care and long‐term residential care services, standardized for client care needs. Canadian Journal on Aging 2007;26:149‐61. CENTRAL

Hughes 1988 {published data only}

Hughes SL, Conrad KJ, Manheim LM, Edelman PL. Impact of long‐term home care on mortality, functional status, and unmet needs. Health Services Research 1988;23:269‐94. CENTRAL

Kane 1991 {published data only}

Kane RA, Kane RL, Illston LH, Nyman JA, Finch MD. Adult foster care for the elderly in Oregon: a mainstream alternative to nursing homes?. American Journal of Public Health 1991;81:1113‐20. CENTRAL

Karakaya 2009 {published data only}

Karakaya MG, Bilgin SC, Ekici G, Kose N, Otman AS. Functional mobility, depressive symptoms, level of independence, and quality of life of the elderly living at home and in the nursing home. Journal of the American Medical Directors Association 2009;10:662‐6. CENTRAL

Kelley‐Gillespie 2011 {published data only}

Kelley‐Gillespie N. A secondary analysis of perceptions of quality of life of older adults residing in a nursing home and assisted living setting using an integrated conceptual model of measurement. Applied Research Quality Life 2012;7:137‐54. CENTRAL

Kuo 2010 {published data only}

Kuo YC, Lan CF, Chen LK, Lan VM. A secondary analysis of perceptions of quality of life of older adults residing in a nursing home and assisted living setting using an integrated conceptual model of measurement. Applied Research in Quality of Life 2010;7:159‐63. CENTRAL

Lane 2004 {published data only}

Lane CJ, Bronskill SE, Sykora K, Dhalla IA, Anderson GM, Mamdani MM, et al. Potentially inappropriate prescribing in Ontario community‐dwelling older adults and nursing home residents. Journal of the American Geriatrics Society 2004;52:861‐6. CENTRAL

Marek 2012 {published data only}

Marek KD, Stetzer F, Adams SJ, Popejoy LL, Rantz M. Aging in place versus nursing home care: comparison of costs to Medicare and Medicaid. Research in Gerontological Nursing 2012;5:123‐9. CENTRAL

Nikmat 2013 {published data only}

Nikmat AW, Hawthorne G, Al‐Mashoor SH. The comparison of quality of life among people with mild dementia in nursing home and home care: a preliminary report. Dementia 2015;14:114‐25. CENTRAL

Page 2009 {published data only}

Page C, Conner T, Prokhorov A, Fang Y, Post L. The effect of care setting on elder abuse: results from a Michigan survey. Journal of Elder Abuse & Neglect 2009;21:239‐52. CENTRAL

Powers 1985 {published data only}

Powers JS, Burger C. Home health care vs nursing home care for the elderly. Journal of the Tennessee Medical Association 1995;78:227‐30. CENTRAL

Skellie 1982 {published data only}

Skellie FA, Mobley GM, Coan RE. Cost‐effectiveness of community‐based long‐term care: current findings of Georgia's alternative health services project. American Journal of Public Health 1982;72:353‐8. CENTRAL

Wilson 2007 {published data only}

Wilson RS, McCann JJ, Li Y, Aggarwal NT, Gilley DW, Evans DA. Nursing home placement, day care use, and cognitive decline in Alzheimer's disease. American Journal of Psychiatry 2007;164:910‐5. CENTRAL

Craig 2008

Craig P, Diepp P, Macintyre S, Michie S, Nazareth I, Petticrew M. Developing and evaluating complex interventions: the new Medical Research Council guidance. BMJ 2008;337:a1655.

EPOC 2013

Effective Practice, Organisation of Care (EPOC). Data collection form. EPOC Resources for review authors. Oslo: Norwegian Knowledge Centre for the Health Services. 2013 Available from epoc.cochrane.org/epoc‐specific‐resources‐review‐authors.

EPOC 2013a

Effective Practice, Organisation of Care (EPOC). EPOC worksheets for preparing a Summary of Findings (SoF) table using GRADE. EPOC Resources for review authors. 2013. Available from epoc.cochrane.org/epoc‐specific‐resources‐review‐authors.

EPOC 2015

Effective Practice, Organisation of Care (EPOC). Suggested risk of bias criteria for EPOC reviews. EPOC Resources for review authors. Oslo: Norwegian Knowledge Centre for the Health Services, 2015. Available from epoc.cochrane.org/epoc‐specific‐resources‐review‐authors.

EPOC 2016

Effective Practice, Organisation of Care (EPOC). What study designs should be included in an EPOC review? EPOC Resources for review authors. 2016. Available from epoc.cochrane.org/epoc‐specific‐resources‐review‐authors.

Higgins 2011

Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0. (updated March 2011). The Cochrane Collaboration, 2011. Available from cochrane‐handbook.org.

Iwarsson 2007

Iwarsson S1, Wahl HW, Nygren C, Oswald F, Sixsmith A, Sixsmith J, et al. Importance of the home environment for healthy aging: conceptual and methodological background of the European ENABLE–AGE Project. Gerentologist 2007;47(1):78‐84.

Katz 1963

Katz S, Ford AB, Moskowitz RW, Jackson BA, Jaffe MW. Studies of illness in the aged: the index of ADL: a standardized measure of biological and psychosocial function. JAMA 1963;185(12):914‐9.

Mahoney 1965

Mahoney FI, Barthel D. Functional evaluation: the Barthel Index. Maryland State Medical Journal 1965;14:56‐61.

Morrison 2012

Morrison A, Polisena J, Husereau D, Moulton K, Clark M, Fiander M, et al. The effect of English‐language restriction on systematic review‐based meta‐analyses: a systematic review of empirical studies. International Journal of Technology Assessment in Health Care 2012;28(2):138‐144. [DOI: 10.1017/S0266462312000086]

Mueller 2007

Mueller PS, Montori VM, Bassler D, Koenig BA, Guyatt GH. Ethical issues in stopping randomized trials early because of apparent benefit. Annals of Internal Medicine 2007;146(12):878‐881. [DOI: 10.7326/0003‐4819‐146‐12‐200706190‐00009]

WHOQOL Group 1995

The WHOQOL Group. The World Health Organization quality of life assessment (WHOQOL): position paper from the World Health Organization. Social Science & Medicine 1995;41(10):1403‐9.

References to other published versions of this review

Mottram 2002

Mottram P, Pitkala K, Lees C. Institutional versus at‐home long term care for functionally dependent older people. Cochrane Database of Systematic Reviews 2002, Issue 1. [DOI: 10.1002/14651858.CD003542]

Young 2012

Young C, van de Glind EMM, Quinn TJ, Hooft L, Legg LA, van Munster BC, et al. At‐home versus institutional long‐term‐care for chronic functionally dependent older people. Cochrane Database of Systematic Reviews 2012, Issue 6. [DOI: 10.1002/14651858.CD009844]

Characteristics of studies

Characteristics of included studies [ordered by study ID]

Braun 1987

Methods

Study design: nested case‐control study

Participants

Participants: N = 98 (Control N = 49; Intervention: N = 49)

Mean age: Control: 79.9 years, Intervention: 81.6 years

Gender: Control: 57% female, intervention: 80% female

Setting: Hawaii

Interventions

Type of intervention: care in participant's own home

Description of the intervention: participants receiving care in their own home from the Nursing Home Without Walls Program. Nursing Home Without Walls (NHWW) provides an array of services including case management, skilled nursing, personal care, adult day health, home delivered meals, nutritional counselling, transportation, respite, emergency alarms, moving assistance, rehabilitation, home maintenance, environmental modifications, homemakers

Control: nursing home care

Outcomes

Happiness at 3 months; physical function at 3 months (ADL)

Notes

Study supported by the Hawaii Department of Social Services and Housing; and the Henry J Kaiser Foundation (California, USA)

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

Non‐randomised trial. Notes from text: since agency procedures did not permit random assignment to placement settings, sample groups were selected. Intermediate Care Facility patients ≥ 55 years of age who staying in one of the three settings for 3 months were considered. They were then matched on ADL, mobility and orientation scores.

Allocation concealment (selection bias)

High risk

No allocation concealment used

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

It is unclear if the staff delivering care or the participants were aware of the study.

Blinding of outcome assessment (detection bias)
Objective

Low risk

N/A ‐ no objective outcomes

Blinding of outcome assessment (detection bias)
Subjective

Unclear risk

Data obtained from self‐report surveys

Incomplete outcome data (attrition bias)
All outcomes

Low risk

Follow‐up rate was either 100% or 88% for all outcomes

Selective reporting (reporting bias)

Low risk

All outcomes reported

Baseline measures

Unclear risk

The participants in each group were matched based on ADL, mobility and orientation. Across groups, age, ADL and mobility are similar

Free of contamination

Low risk

No crossover

Other bias

High risk

Possible reverse causality

Braun 1991

Methods

Study design: non‐randomised trial

Participants

Participants: N = 352 (Control: 131; Intervention: 221 [foster care N = 138, home care N = 83])

Mean age: Control: 79.85 years, Intervention: 78.83 years

Gender: Control: 62% female, Intervention: 63% female.

Setting: Hawaii

Interventions

Type of intervention: foster home care or care at home

Description of the intervention: care provided in a foster home setting with comprehensive Intermediate Care Facility home services.

Control: nursing home care

Outcomes

Mortality at 6 months, change in ADL at 6 months using Katz Index of ADLs

Notes

Baseline imbalances include reduced prevalence of dementia in those allocated to care in community.

Note: patients received foster care or care in their own home. Care in their own home was provided by Nursing Without Walls. Case managers arrange a package of services for the family, most commonly personal care, chore service, meals, home modifications, and transportation. In all, the study involved 131 patients in 10 nursing homes, 138 patients in 98 foster homes, and 83 patients in their own homes, for a total of 352 patients. In this case the intervention arm data combined both foster and home care, with most data coming from foster care and thus, we could not include the results for analysis in the comparison of home care with nursing care.

Study supported by the Hawaii Department of Social Services and Housing; and the Henry J Kaiser Foundation (California, USA)

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

This is not a randomised trial. As described, the study uses a 2‐step Heckman procedure to further control for selection bias before comparing outcomes of 352 patients in nursing homes and community care.

Allocation concealment (selection bias)

High risk

No allocation concealment used

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Participants had to provide informed consent, so they were likely unblinded. Unclear if personnel were aware of study

Blinding of outcome assessment (detection bias)
Objective

Low risk

Data obtained from medical records

Blinding of outcome assessment (detection bias)
Subjective

Unclear risk

Data obtained from self‐report survey

Unclear if the personnel were aware of the study purpose or if this was similar to routinely collected data. All data were collected by 2 hospital staff members (one fluent in Japanese) within a few days of admission to the long‐term care setting by observing and interviewing patients, reviewing charts, and discussing patient physical function with formal and informal caregivers.

Incomplete outcome data (attrition bias)
All outcomes

Unclear risk

For mortality this would be low as data is available for all participants; however, it would be high for physical function.

Timing of and reason for discharge were available for all 352 members of the sample. Six‐month ADL and mobility scores were available for the 220 patients still in placement at the end of 6 months: 54 (65%) in Nursing Home Without Walls, 80 (58%) in foster care, and 86 (65%) in nursing homes.

Selective reporting (reporting bias)

Low risk

All outcomes reported

Baseline measures

High risk

Groups differed at baseline on several factors, including ethnicity and comorbidities such as dementia, cancer and musculoskeletal diagnoses, as well as baseline levels of medications used, ADL function and mobility levels.

Free of contamination

Low risk

No crossover

Other bias

High risk

Possibility of reverse casualty

Challis 1991

Methods

Study design: non‐randomised trial

Participants

Participants: N = 214 (Control: 113; Intervention: 101)

Mean age: Control: 81 years; Control: 80 years

Gender: Control: 65% female; Intervention: 64% female

Setting: UK

Interventions

Type of intervention: care in own home

Description of the intervention: people receiving care in their own home from the Darlington Care Project. Darlington Care Project: case management service, which could include any number of medical services based on client needs (speech therapy, stoma care, catheter care, change of dressing). Personal care (bathing, dressing, toileting, feeding, hand/nail care), physical care, (assist with walking, lifting/transferring). Social and recreational activities and therapeutic exercises

Control: long‐stay care wards

Outcomes

Mortality at 6 and 12 months, subjective well‐being at 6 months

Notes

Increased social disturbance in participants allocated to nursing home care, increased length of stay for control patients

No information about funding sources.

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

Non‐randomised trial. The study compared individual cases receiving services from the project group with a similar group of patients in LTC in adjacent health districts. Groups were not randomly allocated to receive a particular intervention.

Allocation concealment (selection bias)

High risk

No allocation to conceal

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Personnel and participants in the home care group were likely unblinded as part of the Darlington Care Project.

Blinding of outcome assessment (detection bias)
Objective

Low risk

Data obtained from medical records

Blinding of outcome assessment (detection bias)
Subjective

Unclear risk

Data obtained from self‐report surveys

Incomplete outcome data (attrition bias)
All outcomes

Unclear risk

100% of data participant data available on mortality; however, likely high risk for quality of life with less than 60% of cases providing data

Selective reporting (reporting bias)

Low risk

All outcomes reported

Baseline measures

Unclear risk

Age and disability appear similar at baseline; however, there may be difference in social disturbance and length of stay indicating a possible selection effect

Free of contamination

Low risk

No crossover

Other bias

High risk

Potential for baseline confounding

Chuang 2005

Methods

Study design: non‐randomised trial

Participants

Participants: N = 474 (Control: HCBC, N = 144; FC, N = 264; Intervention: N = 66)

Mean age: 71.2 years

Gender: 46% female

Participants were included if they had had a stroke

Setting: Taiwan

Interventions

Type of intervention: care in the community

Description of the intervention: people receiving care in the community. This was either respite care, day care, home maker services or care provided by a live‐in personal helper

Control: nursing home care

Outcomes

Mortality at 6 months, physical function at 6 months

Notes

This study was longitudinal and classified patients into groups depending on the type of care they had received in the previous 6 months. There were 3 categories of care: institution (INS), home‐ or community‐based care (HCBC), and family care (FC). Since family care was defined as only receiving care solely by a family member with no formal care services, this group was not included for analysis in the main comparison.

Study supported by the National Health Research Institute, Taiwan

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

Non‐randomised trial. This study used a longitudinal quasi‐experimental study design following stroke patients 6 months after discharge

Allocation concealment (selection bias)

High risk

Participants were allocated based on their self‐report of LTC received during the telephone survey

Blinding of participants and personnel (performance bias)
All outcomes

High risk

Hospitals and patients were unblinded to study. Page 67‐68: "formal approvals of the study were obtained from the hospitals. Patients and their families were given a written statements describing the purpose of the study". It is unclear if formal care providers were blinded.

Blinding of outcome assessment (detection bias)
Objective

Low risk

Data obtained from medical records

Blinding of outcome assessment (detection bias)
Subjective

Unclear risk

Data obtained from self‐report surveys

Incomplete outcome data (attrition bias)
All outcomes

Low risk

It appears that 100% of data provided for mortality

Selective reporting (reporting bias)

Low risk

All outcomes reported

Baseline measures

Unclear risk

Unclear

Free of contamination

Low risk

No crossover

Other bias

High risk

Potential for residual confounding

Condelius 2010

Methods

Study design: observational cohort study, data set

Participants

Participants: N = 694 (Control: N = 477 [special accommodation: N = 269], Intervention N = 402 [home care: N = 425])

Mean age: 80 years

Gender: 65% female

Participanst were included if they had one or more hospital admission during the year 2001, were aged 65 years or older and received long‐term care and services from the municipality

Setting: Sweden

Interventions

Type of intervention: care in own home

Description of the intervention: participants receiving at least 4 visits per month in their home from care services. Help with laundry, shopping, cleaning, and personal care. Excluded meals on wheels or transport services

Control: nursing home care

Outcomes

Hospital visits and outpatient usage at 1 year; physical function (assessed using ADL staircase); general health (assessed using a 6‐item health complaints questionnaire); mental health (assessed using the Berger scale)

Data were collected by means of a form completed by Registered Nurses, assistant officers, physiotherapists, or occupational therapists. The form comprises questions concerning demographic data, physical function, health complaints, adaptation and standard of housing and formal and informal care.

Notes

Baseline imbalances included younger age and less dependency in those living at home

Study supported by the Vardal Institute (Sweden); the Swedish Institute for Health Sciences; and the Faculty of Medicine, Unit of Caring Sciences, Lund University, Sweden

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

Not a randomised trial. Using routinely collected data within an existing data set

Allocation concealment (selection bias)

High risk

No allocation methods used.

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

Unclear if consent was obtained for this study. Since this is just an analysis of an existing data set, it is unlikely that participants are aware of this study.

Blinding of outcome assessment (detection bias)
Objective

Unclear risk

Data from medical records. Data were collected as part of another national study on ageing ‐ unlikely data collection team were aware of this study aim

Blinding of outcome assessment (detection bias)
Subjective

Unclear risk

Data obtained from self‐report surveys

Incomplete outcome data (attrition bias)
All outcomes

Low risk

All outcomes reported

Selective reporting (reporting bias)

Low risk

All outcomes of interest were reported.

Baseline measures

High risk

Participant characteristics differed between groups. Participants that received care at home were younger, lived with someone, less dependent and less depressed mood.

Free of contamination

Low risk

No crossover

Other bias

High risk

Possibility of reverse causality

Mitchell 1978

Methods

Study design: non‐randomised trial

Participants

Participants N =195. (Control: N = 87; Intervention: N = 108)

Mean age: 65.6 years

Gender: All patients were male

Setting: USA

Interventions

Type of intervention: care in own home

Description of the intervention: participants receiving care in their own home from a home care team including physician, nurse, dietician and social worker as a minimum. Medical care and ancillary services in participant's own home. A potential caregiver (friend, relative, or hired caretaker) must be living in the patient's home and able to assume responsibility for care.

Control: nursing home care

Outcomes

Disability at 3 months using functional status index

Notes

Partially supported by a doctoral training grant from the Department of Medicine and Surgery, Veterans Administration (USA)

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

Non‐randomised trial (page 443). As random assignment of participant could not be achieved, it was necessary to control for differences in initial health status; the VA hospitals were not chosen randomly.

Allocation concealment (selection bias)

High risk

No allocation methods used

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

Unclear. it is not reported if participants knew of the study or its aims

Blinding of outcome assessment (detection bias)
Objective

Unclear risk

N/A ‐ no objective outcomes

Blinding of outcome assessment (detection bias)
Subjective

Unclear risk

Data from self‐report survey. It is not reported if the social workers collecting the data were blinded to study aims

Incomplete outcome data (attrition bias)
All outcomes

Low risk

The total sample was 195, not one of whom was lost to follow‐up.

Selective reporting (reporting bias)

Low risk

All outcomes reported

Baseline measures

Low risk

Adjustments made, including for initial health status

Free of contamination

Low risk

No crossover

Other bias

High risk

Potential for residual confounding

Oktay 1987

Methods

Study design: randomised trial

Participants

Participants: N = 112 (Control: N = 53; Intervention: N = 59)

Meand age: Control: 69.8 years, Intervention: 70.2 years

Gender: Control 64.2% female, Intervention 64.6% female

Setting: USA

Interventions

Type of intervention: care in foster home

Description of the intervention: people living in a foster home setting. Caregivers provided the patient with meals, laundry, assistance with personal and instrumental ADLS, 24‐hour supervision and nursing tasks as needed (e.g. monitoring medication, injections and behavioural modification)

Control: nursing home care

Outcomes

all outcomes were measured at 12 months, Mortality, attitudes‐life satisfaction, attitudes‐perceived health, physical function, basic ADL and instrumental ADL, mental status

Notes

Study supported by the Robert Wood Johnson Foundation, USA

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

Unclear risk

Unclear how the random sequence was generated

Allocation concealment (selection bias)

Low risk

Random sequence was placed in sealed envelopes and opened in sequence by a blinded research assistance once a patient was deemed eligible (page 1506).

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

No blinding of participants. Unclear if personnel were aware of study aim.

Blinding of outcome assessment (detection bias)
Objective

Low risk

Data obtained from medical records

Blinding of outcome assessment (detection bias)
Subjective

Unclear risk

Data obtained from self‐report survey. It is not reported if the social workers collecting the data were blinded to study aims.

Incomplete outcome data (attrition bias)
All outcomes

High risk

22% loss to follow‐up

Selective reporting (reporting bias)

Unclear risk

All outcomes reported but no means or measures of variability reported for any outcome

Baseline measures

High risk

Groups were different at baseline on ethnicity and marital status, which could influence outcome

Free of contamination

Low risk

No crossover

Other bias

Low risk

Randomised trial. Note: only 20% of the eligible sample agreed to participate in the study

Sherwood 1986

Methods

Study design: observational cohort study

Participants

Participants: N = 98 (Control: N = 49, Intervention: N = 49)

Setting: USA

Interventions

Type of intervention: care in foster home

Description of the intervention: people living foster homes and receiving services through the Pennsylvania Domiciliary Care Programme. Foster homes provide personal care services for 1‐3 clients. Counselling, transportation, meals, recreational activities, information/referral, and monitoring services. Based on a patient assessment, the programme could provide medication monitoring, and/or arrange for various types of therapies

Control: nursing home care

Outcomes

All outcomes were measured at 9 months. Community integration and feeling of contentment; utilisation of skills for independent living

Notes

Study supported by the Department of Health and Human Services, USA

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

Non‐randomised trial

Allocation concealment (selection bias)

High risk

No allocation methods used

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

It is unclear if participants or personnel had knowledge of the study aim.

Blinding of outcome assessment (detection bias)
Objective

Unclear risk

N/A ‐ no objective outcomes

Blinding of outcome assessment (detection bias)
Subjective

Unclear risk

Data obtained from self‐report. It is unclear if the trained interviewers collecting data knew of the study aim or patient allocation. Additionally some data on services were collected by a third party.

Incomplete outcome data (attrition bias)
All outcomes

Low risk

The sample sizes at baseline and follow‐up appear similar

Selective reporting (reporting bias)

High risk

Authors selectively reported results

Baseline measures

Low risk

Simulated random group assignment computer procedure used to match groups by large number of variables

Free of contamination

Low risk

No crossover

Other bias

High risk

Baseline confounding

Wilson 2005

Methods

Study design: observational cohort study

Participants

Participants: N = 11,803 (Control: N = 4774; Intervention: N = 7029)

Mean age: Control: 83 years, Intervention: 81 years

Gender: Control 74.3% female, Intervention 76.9% female

Setting: Canada

Interventions

Type of intervention: care in own home

Description of the intervention: people living in own home receiving home care services

Control: nursing home care

Outcomes

Admission to hospital over a 2‐year period

Notes

Study supported by the Health Research Fund of the Alberta Heritage Foundation for Medical Research, Canada

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

Non‐randomised trial

Allocation concealment (selection bias)

High risk

No allocation methods used

Blinding of participants and personnel (performance bias)
All outcomes

Low risk

This study used retrospective, routinely collected data and thus participants or personnel were unaware of the study aim

Blinding of outcome assessment (detection bias)
Objective

Low risk

Data obtained from medical records

Blinding of outcome assessment (detection bias)
Subjective

Unclear risk

N/A ‐ no subjective outcomes

Incomplete outcome data (attrition bias)
All outcomes

Low risk

It would appear that all data were obtained for the cohort of interest. There was some missing data identified during the data cleaning process but was described as < 1%

Selective reporting (reporting bias)

Low risk

All outcomes of interest appear to be reported with point estimates and measures of variance

Baseline measures

High risk

Limited data provided on key baseline characteristics with no adjustment for baseline status

Free of contamination

Low risk

No crossover

Other bias

High risk

Potential multiple baseline confounders

Wysocki 2014

Methods

Study design: observational cohort study, dataset

Participants

Participants: N = 2338 (Control: N = 1169; Intervention: N = 1169)

Age: range 65‐91

Gender: Control: 75% female; Intervention: 73% female

Setting: USA

Interventions

Type of intervention: care in own home or community

Description of the intervention: home‐ and community‐based services provided by Medicaid within the first month after being discharged from a nursing home in which they had received care for at least 90 days (called transitioners)

Control: nursing home care (called stayers)

Outcomes

All outcomes were assessed at 12 months. Primary outcome: potentially preventable hospitalisations: hospitalisations with an ambulatory case‐sensitive condition

Secondary: hospitalisations of any type

Notes

The total populations included 32,504 stayers and 1,942 transitioners. The study sample used a propensity score matching method (page 73). After matching the sample this study included 1169 in each group.

Study supported by the Centers for Medicare and Medicaid Services, USA

Risk of bias

Bias

Authors' judgement

Support for judgement

Random sequence generation (selection bias)

High risk

Non‐randomised trial

Allocation concealment (selection bias)

High risk

No allocation methods used

Blinding of participants and personnel (performance bias)
All outcomes

Unclear risk

This study used data from 7 US states, routinely collected as part of an ongoing initiative to examine progress for rebalancing LTC programs ‐ it is unlikely that participants or personnel were aware of this study aim

Blinding of outcome assessment (detection bias)
Objective

Unclear risk

Data obtained from medical records

Blinding of outcome assessment (detection bias)
Subjective

Low risk

N/A ‐ no subjective outcomes

Incomplete outcome data (attrition bias)
All outcomes

Low risk

All data were available for the included sample

Selective reporting (reporting bias)

Low risk

Data were reported for all outcomes of interest with point estimates and measures of variance

Baseline measures

Low risk

Groups were matched on key criteria (age, gender, ethnicity, residence, diagnosis, ADLs and cognitive impairment) and appear similar.

Free of contamination

Low risk

No crossover

Other bias

Unclear risk

Potential multiple baseline confounders

ADL: activities of daily living; FC: family care; HCBC: home‐ or community‐based care; LTC: long‐term care; N/A: not applicable

Characteristics of excluded studies [ordered by study ID]

Study

Reason for exclusion

Anstey 2007

Does not look at enhanced domiciliary services

Beerens 2014

Cross‐sectional survey

Boggatz 2009

Looks only at barriers to acceptance of care models

Bowling 1991

Does not include enhanced home care services

Boyle 2004

Groups different at baseline

Brajkovic 2009

Cross‐sectional survey

Brennan 2003

Does not look at functionally dependent older people in the community

Chappell 2004

Only lists economic data

Davis 2005

Looks at assessment of dementia in 3 different settings

Hasson 2011

Cross‐sectional survey

Hollander 2007

No robust outcome data reported

Hughes 1988

Does not include institutional care setting

Kane 1991

Does not include stated primary or secondary outcomes

Karakaya 2009

Does not look at functionally dependent older people in the community

Kelley‐Gillespie 2011

Observational before after study with no control

Kuo 2010

Does not include stated primary or secondary outcomes

Lane 2004

Does not look at functionally dependent older people in the community

Marek 2012

Only lists economic data

Nikmat 2013

Cross‐sectional survey

Page 2009

Does not include stated primary or secondary outcomes

Powers 1985

Cost analysis study

Skellie 1982

Does not include institutional care setting

Wilson 2007

Does not fit defined interventions and outcomes

Data and analyses

Open in table viewer
Comparison 1. At‐home versus institutional long‐term care

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mortality Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

Analysis 1.1

Comparison 1 At‐home versus institutional long‐term care, Outcome 1 Mortality.

Comparison 1 At‐home versus institutional long‐term care, Outcome 1 Mortality.

2 Number of patients with a hospital admission Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

Analysis 1.2

Comparison 1 At‐home versus institutional long‐term care, Outcome 2 Number of patients with a hospital admission.

Comparison 1 At‐home versus institutional long‐term care, Outcome 2 Number of patients with a hospital admission.

Study flow diagram.
Figuras y tablas -
Figure 1

Study flow diagram.

Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
Figuras y tablas -
Figure 2

Risk of bias summary: review authors' judgements about each risk of bias item for each included study.

Comparison 1 At‐home versus institutional long‐term care, Outcome 1 Mortality.
Figuras y tablas -
Analysis 1.1

Comparison 1 At‐home versus institutional long‐term care, Outcome 1 Mortality.

Comparison 1 At‐home versus institutional long‐term care, Outcome 2 Number of patients with a hospital admission.
Figuras y tablas -
Analysis 1.2

Comparison 1 At‐home versus institutional long‐term care, Outcome 2 Number of patients with a hospital admission.

Home or foster home versus institutional long‐term care for functionally dependent older people

Patient or population: older adults with functional dependence

Settings: long‐term care

Intervention: long‐term home care

Comparison: long‐term institutional care

Outcomes

Relative effect
(95% CI)

No of participants
(studies)

Certainty of evidence
(GRADE)

Comments

Mortality (6 months)

It is uncertain whether long‐term home care compared to nursing home care decreases mortality risk

Estimates ranged from a relative increase in risk of mortality of RR 2.89 (95% CI 1.57 to 5.32) to a relative reduction in risk of RR 0.38 (95% CI 0.17 to 0.61).

314*
(2 studies)

⊕⊝⊝⊝
Very lowa,b,c

Data were not pooled due to the high degree of statistical heterogeneity for this outcome (I2 = 94%)

Physical function

(3‐6 months)

It is uncertain whether long‐term home care compared to nursing home care improves physical function

Estimates ranged from and improvement in activities of daily living of MD −0.25 points (95% CI −0.44 to −0.06) to MD −1.90 (95% CI −2.18 to −1.62)

1295*
(5 studies)

⊕⊝⊝⊝
Very lowa,b,c

3 studies reporting data used the Katz Index of ADLs or a variation of this measure

2 studies did not provide usable post or change‐score data.

1 study reported no between‐group difference in change in ADLs. 2 studies reported improvements in ADLs for participants receiving home LTC compared to nursing home LTC

Quality of life

(3‐6 months)

It is uncertain whether long‐term home care compared to nursing home care improves happiness (RR 1.97, 95% CI 1.27 to 3.04) or general satisfaction

114
(2 studies)

⊕⊝⊝⊝
Very lowa,b,c

Both studies used proxy items for this outcome.

While both variables were assessed using continuous measures, authors further dichotomised the outcome for reporting, precluding meta‐analysis.

Hospital admissions

It is uncertain whether long‐term home care compared to nursing home care decreases hospital admissions

Estimates ranged from a relative increase in risk of a hospitalisation of RR 2.75 (95% CI 2.59 to 2.92) to a relative reduction in risk of RR 0.82 (95% CI 0.72 to 0.93).

14,853 (3 studies)

⊕⊝⊝⊝
Very lowa,b,c

This outcome described the number of participants having at least one hospital admission. Data were not pooled due to the high degree of statistical heterogeneity for this outcome (I2 = 99%)

Number of adverse health outcomes

The extent to which long‐term home care was associated to more or fewer adverse health outcomes than nursing home care was not reported.

‐‐‐

‐‐‐

‐‐‐

ADL: activities of daily living; CI: confidence interval; LTC: long‐term care; RR: risk ratio.

GRADE Working Group grades of evidence
High certainty: further research is very unlikely to change our confidence in the estimate of effect.
Moderate certainty: further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low certainty: further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low certainty: we are very uncertain about the estimate.

aDowngraded due to study design.
bDowngraded due to risk of bias.
cDowngraded due to inconsistency.

* For Chuang 2005, only participants receiving institutional or home/community‐based care were included; participants receiving family care were not included.

Figuras y tablas -
Table 1. Description of long‐term home care interventions

Study

Service Location (home / community)

Type of services

Dose (how many services and their frequency of provision)

Provider

Condelius 2010

Home

Help with laundry, shopping, cleaning, and personal care. Excluded meals on wheels or transport services

≥ 4 home visits per month

Not reported

Mitchell 1978

Home

Medical care and ancillary services in participant's own home. A potential caregiver (friend, relative, or hired caretaker) must be living in the patient's home and able to assume responsibility for care.

Not reported

Home care team (physician, nurse, dietician, social worker)

Challis 1991

Home

Darlington Care Project: case management service, which could include any number of medical services based on client needs (speech therapy, stoma care, catheter care, change of dressing). Personal care (bathing, dressing, toileting, feeding, hand/nail care), physical care, (assist with walking, lifting/transferring). Social and recreational activities and therapeutic exercises

Not reported

Case manager likely a nurse? Other HCPs as needed

Wilson 2005

Home

Not reported

Not reported

Not reported

Wysocki 2014

Home or community

Not reported

Not reported

Not reported

Chuang 2005

Home or community

Not reported

Not reported

Not reported

Braun 1987

Home or community

Nursing Home Without Walls (NHWW) provides an array of services including case management, skilled nursing, personal care, adult day health, home delivered meals, nutritional counselling, transportation, respite, emergency alarms, moving assistance, rehabilitation, home maintenance, environmental modifications, homemakers

Not reported

Nurse

Sherwood 1986

Community

Counselling, transportation, meals, recreational activities, information/referral, and monitoring services. Based on a patient assessment, the programme could provide medication monitoring, and/or arrange for various types of therapies

Not reported

Social worker/nurse

Figuras y tablas -
Table 1. Description of long‐term home care interventions
Table 2. Description of long‐term geriatric foster care interventions

Study

Service Location

Type of services

Provider

Oktay 1987

Room in a foster home

Caregivers provided the patient with meals, laundry, assistance with personal and instrumental ADLS, 24‐hour supervision and nursing tasks as needed (e.g. monitoring medication, injections and behavioural modification)

Caregivers were trained by the Johns Hopkins Hospital

Sherwood 1986

Foster home care

Caregivers provided personal care services, 24‐hour supervision, and meal, laundry and household services

Caregivers were a part of a certification and monitoring programme

Braun 1987

Foster care home

Community Care Program: families provide 24‐hour supervision, room and board, homemaker services, personal care including assistance with ADLs, medication, range of motion and other exercises, and in some cases, tube feeding, dressing changes, insulin injections, catheter irrigations, transportation to medical and social outings

Families are trained and supervised by social worker/nurse teams to adopt and care for 1‐2 patients

Figuras y tablas -
Table 2. Description of long‐term geriatric foster care interventions
Table 3. Mortality: data for all included studies reporting this outcome

Study

Time‐point

Type of long‐term care

Sample size

Results

Relative effect RR (95% CI)

Home care

Nursing home

Braun 1991

6 months

Blended

352

8% (18/221)

16% (21/131)

0.51 (0.28 to 0.92)

Challis 1991

6 months

Home care

214

34% (31/101)

11% (12/113)

2.89 (1.57 to 5.32)

Chuang 2005

6 months

Home care

474

poststroke

6% (24/408)

18% (12/66)

0.38 (0.17 to 0.61)

Challis 1991

12 months

Home care

214

40% (40/101)

31% (35/113)

1.28 (0.89 to 1.84)

Oktay 1987

12 months

Foster care

112

29% (17/59)

32% (17/53)

0.90 (0.51 to 1.57)

CI: confidence interval; RR: risk ratio.

RR: risk ratio.

Figuras y tablas -
Table 3. Mortality: data for all included studies reporting this outcome
Table 4. Physical function: data for all included studies reporting this outcome

Study

Time point

Sample size

Measure

D/Ca

Results

Relative effectb (95% CI)

Home care

Nursing home

Home care

Mitchell 1978c

3 months

195

ADLd (change)

Braun 1987

3 months

98

ADLe

C

Post: 13.02

Post: 13.16

Braun 1987

3 months

98

ADL (mobility)e

C

−1.02

−1.05

Chuang 2005

6 months

210

ADLe

Sherwood 1986

9 months

98

ADL

performance assessment

?

−0.25 (−0.44 to −0.06)

Condelius 2010f

Unclear

694

ADLg

C

3.0 (1.2)

3.9 (0.4)

−0.9 (−1.02 to −0.78)

Condelius 2010f

Unclear

694

ADLh

C

1.4 (1.7)

3.4 (1.9)

−1.90 (−2.18 to −1.62)

Foster care

Oktay 1987

12 months

53

ADLd (improved/maintained)

D

79% (22/28)

60% (15/25)

0.19 (−0.07 to 0.43)

Oktay 1987

12 months

53

ADLg

(improved/maintained)

D

75% (21/28)

68% (17/25)

0.07 (−0.17 to 0.31)

Sherwood 1986

9 months

62

ADL

performance assessment

Braun 1987

Unclear

Blended

Braun 1991

6 months

352

ADLe (pre‐post)

C

Pre: 12.87

Post: 12.16

Pre: 14.43

Post: 13.78

Braun 1991

6 months

352

ADLe (change)

0.71

0.65

ADL: activities of daily living; CI: confidence interval; RR: risk ratio.

aD: dichotomous outcome; C: continuous outcome.
bFor dichotomous outcomes, the relative effect is reported as a risk ratio (RR).
cNo post‐test data provided for this study. Pre‐test Functional Status Index mean (SD): home care (HC) 8.12 (3.9), institution (hospital): 10.48 (3.3).
dADLs were assessed with theFunction Status Index (FSI). This measure evaluates people on the extent to which they can perform everyday activities and socially defined roles. The self‐care dimension was expanded to include an item (continence) not in the original FSI. Continence used in ADL‐ Katz total FSI scores ranges from a 0 to 17. Higher score worse.
eADLs assessed with theKatz Index of ADLs (Katz 1963). This measures function in eight activities: bathing, dressing, transfer, toileting, continence, feeding, ambulation, house confinement. ADL is first 6 items summed for total score (range: 6 to 18). Mobility is final 2 items summed for total score (range: 2 to 9) We are using the ADL score. Higher scores worse.
fIn this study, there were no pre‐post measures reported; it appears these data are cross‐sectional, and it is unclear at what time point they were taken.
gADL: Activities of daily living were assessed with the Instrumental Activities of Daily Living (IADL) including cooking, transportation, cleaning and shopping. The IADL sum score ranges from 0 (independent in all activities) to 6 (dependent in all activities).
hADL: Activities of daily living were assessed with thePersonal Activities of Daily Living (PADL) including bathing, dressing, going to the toilet, transferring, continence and feeding. The PADL sum score ranges from 0 (independent in all activities) to 4 (dependent in all activities).

Figuras y tablas -
Table 4. Physical function: data for all included studies reporting this outcome
Table 5. Quality of Life: data for all included studies reporting this outcome

Study

Time point

Type of long‐term care

Sample Size

Measure

D/Ca

Results

Relative effectb

(95% CI)

Favours

Home care

Nursing home

Home care

Braun 1987

3 months

Community care

132

Reported level of happinessc

D

67% (59/88)

34% (15/44)

1.97 (1.27 to 3.04)

Home care

Challis 1991

6 months

Community care

214

General satisfactiond (change)

C

0.79

0.08

Home care

Challis 1991

6 months

Community care

214

Well‐being – moraled (change)

C

0.79

0.21

Home care

Challis 1991

6 months

Community care

214

Well‐being – depressiond (change)

C

0.33

−1.05

Home care

Foster care

Oktay 1987

12 months

Foster care

53

Life satisfaction (improved/maintained)

D

46% (13/28)

72% (18/25)

RR: 0.64 (0.40 to 1.03)

Nursing

Oktay 1987

12 months

Foster care

53

Perceived health (improved/maintained)

D

68% (19/28)

84% (21/25)

RR: 0.81 (0.59 to 1.10)

Nursing

Oktay 1987

12 months

Foster care

53

Mental status (improved/maintained)

D

64% (18/28)

60% (15/25)

RR: 1.07 (0.70 to 1.64)

CI: confidence interval; RR: risk ratio.

aD: dichotomous outcome; C: continuous outcome.
bFor dichotomous outcomes, the relative effect is reported as a risk ratio (RR).
cA single item question, "Are you happy here?" with a 3 point response: 1 = rarely, 2 = sometimes, 3 = often. They report raw response data on each point and then dichotomise data as happy or not. Higher score = better.
dA single item was used but not described. Mean change score at 6 month is reported. SD were not provided. Higher scores are assumed to be better.

Figuras y tablas -
Table 5. Quality of Life: data for all included studies reporting this outcome
Table 6. Hospital admissions: data for all included studies reporting this outcome

Study

Time‐point

Type of long‐term care

Sample Size

Measure

Results

Relative effect: RR (95% CI)

Favours

Home care

Nursing

home

Wilson 2005

Observational

(data set)

Home care

11,803

Hospital admissiona

55%

(3880/7029)

20%

(958/4774)

2.75 (2.59 to 2.92)

Nursing

home?

Wilson 2005

Observational (dataset)

Home care

11,803

Emergency room visitsb

70.1%

(4992/70290

34.8%

(1662/4774)

Nursing

home?

Wysocki 2014

Observational

(dataset)

Home/community care

2338

Preventable

hospitalisationc

11.4%

(133/1169)

9.7%

(113/1169)

Nursing

home?

Wysocki 2014

Observational

(dataset)

Home/community care

2338

Any hospitalisationd

35.8%

(419/1169)

25.4%

(297/1169)

1.41

(1.25, 1.60)

Nursing

home?

Condelius 2010e

unclear

Home care

694

Hospital staysf

53.6%

(228/425)

65.4%

(176/269)

0.82

(0.72, 0.93)

Home care?

CI: confidence interval; RR: risk ratio.

aNumber admitted to hospital at least once.
bNumber of patients having ≥ 1 emergency room visits.
cNumber of patients with at least one potentially preventable hospitalisation.
dNumber of patients with at least one any type hospitalisation.
eIn this study, there were no pre‐post measures reported; it appears these data are cross‐sectional, and it is unclear at what time point they were taken.
fNumber of patients with 1 hospital stay.

Figuras y tablas -
Table 6. Hospital admissions: data for all included studies reporting this outcome
Comparison 1. At‐home versus institutional long‐term care

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Mortality Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

2 Number of patients with a hospital admission Show forest plot

3

Risk Ratio (M‐H, Fixed, 95% CI)

Totals not selected

Figuras y tablas -
Comparison 1. At‐home versus institutional long‐term care