Immune therapies for women with history of failed implantation undergoing IVF treatment
Appendices
Appendix 1. CENTRAL
Database: EBM Reviews ‐ Cochrane Central Register of Controlled Trials <2nd Quarter 2010>
Search strategy:
1 (fail$ adj2 implant$).tw.
2 exp Embryo Implantation/
3 (implant$ adj2 dysfunction$).tw.
4 (Embryo$ adj2 Implant$).tw.
5 (pregnanc$ adj2 fail$).tw.
6 or/1‐5
7 exp immunotherapy/ or exp immunosuppression/
8 (immunotherap$ or immunosuppression).tw.
9 immunoglobulin$.tw.
10 exp Immunoglobulins/
11 (IVI g or IVIg).tw.
12 intralipid$.tw.
13 (immune adj2 therap$).tw.
14 exp Prednisone/
15 Prednisone.tw.
16 corticosteroid$.tw.
17 or/7‐16
18 6 and 17
Appendix 2. MEDLINE
Database: Ovid MEDLINE®, Ovid MEDLINE® In‐Process
Search strategy:
1 (fail$ adj2 implant$).tw.
2 exp Embryo Implantation/
3 (implant$ adj2 dysfunction$).tw.
4 (Embryo$ adj2 Implant$).tw.
5 (pregnanc$ adj2 fail$).tw.
6 or/1‐5
7 exp immunotherapy/ or exp immunosuppression/
8 (immunotherap$ or immunosuppression).tw.
9 immunoglobulin$.tw.
10 exp Immunoglobulins/
11 (IVI g or IVIg).tw.
12 intralipid$.tw.
13 (immune adj2 therap$).tw.
14 exp Prednisone/
15 Prednisone.tw.
16 corticosteroid$.tw.
17 or/7‐16
18 randomized controlled trial.pt.
19 controlled clinical trial.pt.
20 randomized.ab.
21 placebo.tw.
22 clinical trials as topic.sh.
23 randomly.ab.
24 trial.ti.
25 (crossover or cross‐over or cross over).tw.
26 or/18‐25
27 exp animals/ not humans.sh.
28 26 not 27
29 6 and 17 and 28
Appendix 3. EMBASE
Database: EMBASE <1980 to 2010 Week 28>
Search strategy:
1 exp nidation/
2 nidation.tw.
3 (fail$ adj2 implant$).tw.
4 (implant$ adj2 dysfunction$).tw.
5 (Embryo$ adj2 Implant$).tw.
6 (pregnanc$ adj2 fail$).tw.
7 or/1‐6
8 exp immunotherapy/
9 (immunotherap$ or immunosuppression).tw.
10 immunoglobulin$.tw.
11 exp immunoglobulin/
12 (IVI g or IVIg).tw.
13 intralipid$.tw.
14 (immune adj2 therap$).tw.
15 exp prednisone/
16 Prednisone.tw.
17 corticosteroid$.tw.
18 exp corticosteroid therapy/
19 or/8‐18
20 7 and 19
21 Clinical Trial/
22 Randomized Controlled Trial/
23 exp randomization/
24 Single Blind Procedure/
25 Double Blind Procedure/
26 Crossover Procedure/
27 Placebo/
28 Randomi?ed controlled trial$.tw.
29 Rct.tw.
30 random allocation.tw.
31 randomly allocated.tw.
32 allocated randomly.tw.
33 (allocated adj2 random).tw.
34 Single blind$.tw.
35 Double blind$.tw.
36 ((treble or triple) adj blind$).tw.
37 placebo$.tw.
38 prospective study/
39 or/21‐38
40 case study/
41 case report.tw.
42 abstract report/ or letter/
43 or/40‐42
44 39 not 43
45 20 and 44
46 (2009$ or 2010$).em.
47 45 and 46
Appendix 4. PsycINFO
Database: PsycINFO <1806 to July Week 2 2010>
Search strategy:
1 (fail$ adj2 implant$).tw.
2 (implant$ adj2 dysfunction$).tw.
3 (Embryo$ adj2 Implant$).tw.
4 (pregnanc$ adj2 fail$).tw.
5 or/1‐4
6 exp immunotherapy/
7 exp Immunodepression/
8 (immunotherap$ or immunosuppression).tw.
9 immunoglobulin$.tw.
10 exp Immunoglobulins/
11 (IVI g or IVIg).tw.
12 intralipid$.tw.
13 (immune adj2 therap$).tw.
14 exp Corticosteroids/
15 Prednisone.tw.
16 corticosteroid$.tw.
17 or/6‐16
18 5 and 17
Appendix 5. Menstrual Disorders and Subfertility Group (MDSG)
KH1670 Menstrual Disorders and Subfertility Group Database. We will use use the following subject headings and keywords.
Keywords CONTAINS "failed implantation" or "implantation failure" or "Pregnancy loss" or "failure rate" or Title CONTAINS"failed implantation" or "implantation failure" or "Pregnancy loss" or "failure rate"
AND
Keywords CONTAINS "immunoglobulins" or "immunosuppressants" or "Immunosuppression" or "immunotherapy" or "immunological" or "immune response" or "immune system effects" or "prednisolone" or "*Prednisone" or "corticosteriods" or "corticosteroids" or Title CONTAINS"immunoglobulins" or "immunosuppressants" or "Immunosuppression" or "immunotherapy" or "immunological" or "immune response" or "immune system effects" or "prednisolone" or "*Prednisone" or "corticosteriods" or "corticosteroids"
Appendix 6. CINAHL
"IVF" (all text) AND "immunotherapy" (all text)
Appendix 7. PubMed
MeSH major "Fertilization in vitro" AND MeSH "immunotherapy"
