#1

MeSH descriptor Leukemia, Myeloid, Acute explode all trees

#2

MeSH descriptor Leukemia, Myeloid explode all trees

#3

MeSH descriptor Acute Disease explode all trees

#4

(#2 AND #3)

#5

(acut* or akut* or agud* or aigu*)

#6

(myelo* or mielo* or nonlympho* or granulocytic*)

#7

leukem* or leukaem* or leuc*

#8

(#5 AND #6 AND #7)

#9

(aml*)

#10

(#1 OR #4 OR #8 OR #9)

#11

MeSH descriptor Cytarabine explode all trees

#12

cytarabin* or citarabin*

#13

arabino* or arabitin*

#14

aracytine* or aracytidin*

#15

(ara* NEAR/1 cytin*) or (ara* NEAR/1 cytidin*) or (ara* NEAR/1 cytosin*)

#16

cytonal* or cytosar* or cytozar* or depocyt* or cytarbel* or cytarabinum* or alexan* or arabin* or ara cell* or aracytin* or erpalfa* or udicil* or tarabin*

#17

(#11 OR #12 OR #13 OR #14 OR #15 OR #16)

#18

(#10 AND #17)

ID

Search

#1

MeSH descriptor Myelodysplastic Syndromes explode all trees

#2

(myeloplasti* or myelodysplasti* or dysmyelopoietic* or mielodispl*sic*)

#3

(myelodysplasi*)

#4

(mds)

#5

MeSH descriptor Preleukemia explode all trees

#6

(preleuka*)

#7

(#1 OR #2 OR #3 OR #4 OR #5 OR #6)

#8

MeSH descriptor Cytarabine explode all trees

#9

(cytarabin* or citarabin*)

#10

(arabino* or arabitin*)

#11

(aracytine* or aracytidin*)

#12

(ara* NEAR/1 cytin* ) or (arabino* NEAR/1 cytin* ) or (ara* NEAR/1 cytidin* ) or (arabino* NEAR/1 cytidin* )

#13

(ara* NEAR/1 cytosin*) or (arabino* NEAR/1 cytosin*)

#14

(cytidine* or cytine*)

#15

(ara‐c or arac or arafcyt)

#16

(cytonal* or cytosar* or cytozar* or depocyt* or cytarbel* or cytarabinum*)

#17

(alexan* or arabin* or ara cell* or aracytin* or cytarbel* or erpalfa* or udicil* or tarabin* or cytosar* or cytozar*)

#18

(#8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 OR #17)

#19

(#7 AND #18)

1

exp LEUKEMIA, MYELOID, ACUTE/

2

LEUKEMIA, MYELOID/

3

ACUTE DISEASE/

4

2 and 3

5

(acut$ or akut$ or agud$ or aigu$).tw,kf,ot.

6

((myelo$ or mielo$ or nonlympho$ or granulocytic$) and (leuk?em$ or leuc$)).tw,kf,ot.

7

5 and 6

8

aml.tw,kf,ot.

9

1 or 4 or 7 or 8

10

exp CYTARABINE/

11

(cytarabin$ or citarabin$).tw,kf,ot,nm.

12

(arabino$ or arabitin$).tw,kf,ot.

13

(aracytine$ or aracytidin$).tw,kf,ot,nm.

14

((ara$ or arabino$) adj1 (cytin$ or cytidin$ or cytosin$)).tw,kf,ot.

15

(cytidine$ or cytine$).tw,kf,ot.

16

(ara‐c or arac or arafcyt).tw,kf,ot.

17

(cytonal$ or cytosar$ or cytozar$ or depocyt$ or cytarbel$ or cytarabinum$).tw,kf,ot.

18

(alexan$ or arabin$ or ara cell$ or aracytin$ or cytarbel$ or erpalfa$ or udicil$ or tarabin$ or cytosar$ or cytozar$).tw,kf,ot.

19

or/10‐18

20

randomized controlled trial.pt.

21

controlled clinical trial.pt.

22

randomized.ab.

23

placebo.ab.

24

clinical trials as topic.sh.

25

randomly.ab.

26

trial.ti.

27

or/20‐26

28

humans.sh.

29

27 and 28

30

9 and 19 and 29

#

Searches

1

exp MYELODYSPLASTIC SYNDROMES/

2

(myeloplasti$ or myelodysplasti$ or dysmyelopoietic$ or mielodispl?sic$).tw,kf,ot.

3

myelodysplasi$.tw,kf,ot.

4

mds.tw,kf,ot.

5

PRELEUKEMIA/

6

preleuka?m$.tw,kf,ot.

7

or/1‐6

8

exp CYTARABINE/

9

(cytarabin$ or citarabin$).tw,kf,ot,nm.

10

(arabino$ or arabitin$).tw,kf,ot.

11

(aracytine$ or aracytidin$).tw,kf,ot,nm.

12

((ara$ or arabino$) adj1 (cytin$ or cytidin$ or cytosin$)).tw,kf,ot.

13

(cytidine$ or cytine$).tw,kf,ot.

14

(ara‐c or arac or arafcyt).tw,kf,ot.

15

(cytonal$ or cytosar$ or cytozar$ or depocyt$ or cytarbel$ or cytarabinum$).tw,kf,ot.

16

(alexan$ or arabin$ or ara cell$ or aracytin$ or cytarbel$ or erpalfa$ or udicil$ or tarabin$ or cytosar$ or cytozar$).tw,kf,ot.

17

or/8‐16

18

randomized controlled trial.pt.

19

controlled clinical trial.pt.

20

randomized.ab.

21

placebo.ab.

22

drug therapy.fs.

23

randomly.ab.

24

trial.ab.

25

groups.ab.

26

or/18‐25

27

humans.sh.

28

26 and 27

29

7 and 17 and 28

30

7 and 17